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  • Open Access

    REVIEW

    Hot Wall Condensers in Domestic Refrigerators: A Review of Enhancements from Past to Present, Performance Parameters, and Future Perspectives

    Gürcan Durmaz1,*, Gökhan Gürlek2

    Frontiers in Heat and Mass Transfer, Vol.24, No.2, 2026, DOI:10.32604/fhmt.2026.075332 - 30 April 2026

    Abstract This study examines the evolution of condenser technologies in household refrigerators, focusing on the potential for improving energy efficiency with hot-wall condensers (HWCs). Factors influencing this development, including refrigerant changes, consumer expectations, global regulations, and environmental factors, are evaluated. Design features, advantages, disadvantages, limitations, and comparisons with other condenser types are presented for HWCs. The review identifies key parameters affecting HWC performance: pipe diameter and pitch, outer surface material properties, adhesive tape properties, and contact resistances. The effects of environmental factors such as ambient temperatures and heat transfer coefficients are also considered. The results indicate… More > Graphic Abstract

    Hot Wall Condensers in Domestic Refrigerators: A Review of Enhancements from Past to Present, Performance Parameters, and Future Perspectives

  • Open Access

    ARTICLE

    Evaluation of the Antifungal Activity of Aqueous Extracts of Corrigiola telephiifolia and Marrubium vulgare against Major Post-Harvest Citrus Diseases

    Hajar Zennouhi1,2, Rachid Ez-zouggari1,3, Mamadou Traoré1, Abderrahim Lazraq2, Saadia Belmalha4, Rachid Lahlali1,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.4, 2026, DOI:10.32604/phyton.2026.078088 - 28 April 2026

    Abstract Citrus fruits are highly susceptible to post-harvest diseases such as green rot (Penicillium digitatum), blue rot (P. italicum), and sour rot (Geotrichum citri-aurantii), causing significant economic losses. Due to the risks associated with synthetic fungicides and the emergence of resistant strains, natural alternatives are needed. This study evaluated the antifungal activity of aqueous extracts of Corrigiola telephiifolia and Marrubium vulgare. In vitro tests were conducted using PDA medium with extract concentrations of 12.5–100 mg/mL and in vivo assays were performed on artificially wounded oranges with the same extract concentrations. In vitro tests showed strong inhibition of mycelial growth and spore germination, with C. telephiifolia More > Graphic Abstract

    Evaluation of the Antifungal Activity of Aqueous Extracts of <i>Corrigiola telephiifolia</i> and <i>Marrubium vulgare</i> against Major Post-Harvest Citrus Diseases

  • Open Access

    ARTICLE

    Machine Learning (ML) and Molecular Dynamics–Driven Optimization of VEGFR2 Ligands against Hepatocellular Carcinoma

    Farzana Yasmeen1,#, Abdul Manan1,#,*, Wook Kim1, Sangdun Choi1,2,*

    Oncology Research, Vol.34, No.5, 2026, DOI:10.32604/or.2026.076072 - 22 April 2026

    Abstract Objectives: Vascular endothelial growth factor receptor 2 (VEGFR2) is a critical therapeutic target in hepatocellular carcinoma (HCC) due to its role in angiogenesis and tumor progression. While several inhibitors are currently used, clinical utility is often limited by resistance and adverse effects, necessitating the discovery of novel therapeutic agents. The aim of this study was to identify and characterize novel, highly effective VEGFR2 inhibitors using an integrated computational pipeline to advance the development of new HCC treatments. Methods: A comprehensive dataset from the ChEMBL database was curated and standardized for Quantitative Structure-Activity Relationship (QSAR) modeling.… More > Graphic Abstract

    Machine Learning (ML) and Molecular Dynamics–Driven Optimization of VEGFR2 Ligands against Hepatocellular Carcinoma

  • Open Access

    ARTICLE

    Genetic evidence against a causal relationship between myocardial infarction and urological malignancies

    Wei Zhang, Xixi Peng*

    Canadian Journal of Urology, Vol.33, No.2, pp. 387-401, 2026, DOI:10.32604/cju.2026.072565 - 20 April 2026

    Abstract Background: Observational studies have suggested potential associations between myocardial infarction (MI) and cancer risk, but the causal nature of these relationships remains unclear due to confounding factors and reverse causation. We aimed to investigate the bidirectional causal relationships between MI and urinary system cancers using genetic instruments. Methods: We conducted a two-sample Mendelian randomization (MR) analysis using summary statistics from large-scale genome-wide association studies. Genetic variants associated with MI were used as instrumental variables (n = 19 SNPs for prostate cancer [PCa] and malignant neoplasm of kidney [MRN], n = 6 SNPs for bladder cancer,… More >

  • Open Access

    ARTICLE

    Mechanisms of Concrete Durability against Seawater (Case Study: Concrete as Dock)

    Niken Chatarina*, Suyadi Suyadi, Noorhidana Vera Agustriana, Chairani Zilia, Mariyanto Mariyanto

    Structural Durability & Health Monitoring, Vol.20, No.2, 2026, DOI:10.32604/sdhm.2026.067525 - 31 March 2026

    Abstract In strong aggressive areas, Indonesian standards specify a maximum penetration of 30 mm. Concrete utilizes sulfate-resistant Portland Pozzolan Cement (PPC) for a target strength of 30 MPa, with and without silica fume and plastic fiber (SR-SFF-sea and SR-N-SFF). Some samples of SR-N-SFF are immersed in the sea (SR-N-SFF-sea), while others are protected (SR-N-SFF-protected). Additionally, concrete using non-sulfate-resistant cement (NSR-sea) with a strength of 20.75 MPa was also evaluated. All samples were subjected to penetration depth testing according to the DIN EN 12390-8 standard, demonstrating that they met the penetration requirements for intense aggression. The study… More > Graphic Abstract

    Mechanisms of Concrete Durability against Seawater (Case Study: Concrete as Dock)

  • Open Access

    ARTICLE

    Eco-Friendly Combat against Prostate Cancer: Green Chemistry Approach Using Biosynthesized Nanoparticles Functionalized with Propolis for Enhanced Anticancer Activity

    Awatif Rashed Z. Almotairy1,2, Eman Fayad3, Fatimah Hadadi4, Ahmad F. Alhomodi5, Dalal Nasser Binjawhar6, Hanadi A. Katouah7, Bassma H. Elwakil8,*, Keshav Raj Paudel9,10,*, Mostafa El-Khatib11

    Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2025.070645 - 23 March 2026

    Abstract Objectives: Prostate cancer cells often develop mechanisms to evade conventional therapies. Nanomedicine offers the potential for targeted drug delivery, improved tumor accumulation, and reduced systemic toxicity. This study biosynthesizes silver nanoparticles (NPP/AgONPs) functionalized with propolis, evaluates their antibacterial efficacy against uropathogenic strains of Escherichia coli (E. coli), and assesses their cytotoxic effect on cancer cell proliferation using the PC-3, human prostate epithelial cell line. Methods: The synthesized NPP/AgONPs physiochemical parameters were characterized, followed by in vitro assays to evaluate their antibacterial activity against multiple uropathogenic E. coli strains; determining the cytotoxicity against HPrEC and PC-3 cells by measuring cytotoxicity (CC50)… More >

  • Open Access

    ARTICLE

    Molecular Fingerprinting of Three Ex-Situ Cultivated Populations of Acalypha gaumeri Pax & K. Hoffm (Female and Male) and Evaluation of Their Antifungal Activity Against Phytopathogens

    Christian Pérez-Chablé1, Daisy Pérez-Brito1,*, Anuar Magaña-Alvarez1, Jairo Cristóbal-Alejo2, Irma L. Medina-Baizabal1, Marcela Gamboa-Angulo1,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.2, 2026, DOI:10.32604/phyton.2026.072668 - 28 February 2026

    Abstract Acalypha gaumeri (Euphorbiaceae) is the only endemic species of the genus in the Yucatan Peninsula. It is dioecious and has antifungal properties against various phytopathogens. In the present study, molecular identification of A. gaumeri was performed using the rbcL region, confirming its belonging to the Acalypha genus. Its genetic diversity was evaluated using 10 SPAR markers (ISSR and DAMD) from 60 individuals collected from female and male plants of the Kiuic, Tinum and Yaxcaba ex-situ populations. The results showed a high level of genetic polymorphism (PIC = 0.980) and significant differences among the populations. Ethanol and aqueous extracts from… More >

  • Open Access

    ARTICLE

    Improved Gain Shared Knowledge Optimizer Based Reactive Power Optimization for Various Renewable Penetrated Power Grids with Static Var Generator Participation

    Xuan Ruan1, Han Yan2, Donglin Hu1, Min Zhang2, Ying Li1, Di Hai1, Bo Yang3,*

    Energy Engineering, Vol.123, No.3, 2026, DOI:10.32604/ee.2025.071166 - 27 February 2026

    Abstract An optimized volt-ampere reactive (VAR) control framework is proposed for transmission-level power systems to simultaneously mitigate voltage deviations and active-power losses through coordinated control of large-scale wind/solar farms with shunt static var generators (SVGs). The model explicitly represents reactive-power regulation characteristics of doubly-fed wind turbines and PV inverters under real-time meteorological conditions, and quantifies SVG high-speed compensation capability, enabling seamless transition from localized VAR management to a globally coordinated strategy. An enhanced adaptive gain-sharing knowledge optimizer (AGSK-SD) integrates simulated annealing and diversity maintenance to autonomously tune voltage-control actions, renewable source reactive-power set-points, and SVG output.… More >

  • Open Access

    ARTICLE

    Sodium Alginate Nanoemulsions for the Delivery of Eucalyptus staigeriana Essential Oil: Production, Characterization, and Ovicidal and Larvicidal Effects against Haemonchus contortus

    Claudia M. L. Bevilaqua1,*, José Vilemar de Araújo-Filho2, Livia F. Ximenes1, Henety N. Pinheiro1, Flávia O. M. da Silva Abreu3, Débora S. C. M. Castelo Branco4, Ana Carolina F. L. Melo4, Weibson P. P. André1, Wesley L. C. Ribeiro5, Lorena M. B. de Oliveira1

    Journal of Renewable Materials, Vol.14, No.2, 2026, DOI:10.32604/jrm.2025.02025-0138 - 25 February 2026

    Abstract Eucalyptus staigeriana essential oil (EsEO) has well-known anthelmintic activity in small ruminants. However, its volatility limits its therapeutic action. The aim of this study was to develop a water-in-oil sodium alginate-based nanoemulsion with an effective in vitro effect on the eggs and larvae of Haemonchus contortus, a gastrointestinal parasite of sheep and goats. Four oil-in-water sodium alginate-based emulsions were prepared using a high-energy method with different proportions of Tween 80, EsEO, and sodium alginate (ALG) 4%. The physical-chemical characterization included stability, particle size, zeta potential and infrared spectra. The effects of the emulsions were evaluated against H. contortus via… More > Graphic Abstract

    Sodium Alginate Nanoemulsions for the Delivery of <i>Eucalyptus staigeriana</i> Essential Oil: Production, Characterization, and Ovicidal and Larvicidal Effects against <i>Haemonchus contortus</i>

  • Open Access

    ARTICLE

    Defending against Topological Information Probing for Online Decentralized Web Services

    Xinli Hao1, Qingyuan Gong2, Yang Chen1,*

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.073155 - 12 January 2026

    Abstract Topological information is very important for understanding different types of online web services, in particular, for online social networks (OSNs). People leverage such information for various applications, such as social relationship modeling, community detection, user profiling, and user behavior prediction. However, the leak of such information will also pose severe challenges for user privacy preserving due to its usefulness in characterizing users. Large-scale web crawling-based information probing is a representative way for obtaining topological information of online web services. In this paper, we explore how to defend against topological information probing for online web services,… More >

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