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  • Open Access


    Comparative transcriptome analysis provides insights into the molecular mechanism of the anti-nematode role of Arachis hypogaea (Fabales: Fabaceae) against Meloidogyne incognita (Tylenchida: Heteroderidae)


    BIOCELL, Vol.47, No.9, pp. 2101-2113, 2023, DOI:10.32604/biocell.2023.029581

    Abstract Background: Plant root-knot nematode (RKN) disease is a serious threat to agricultural production across the world. Meloidogyne incognita is the most prominent pathogen to the vegetables and cash crops cultivated. Arachis hypogaea can effectively inhibit M. incognita, but the underlying defense mechanism is still unclear. Methods: In our study, the chemotaxis and infestation of the second-stage juveniles (J2s) of M. incognita to A. hypogaea root tips were observed by the Pluronic F-127 system and stained with sodium hypochlorite acid fuchsin, respectively. The transcriptome data of A. hypogaea roots with non-infected or infected by J2s were analyzed. Results: The J2s could… More >

  • Open Access


    A Stroke-Limitation AMD Control System with Variable Gain and Limited Area for High-Rise Buildings

    Zuo-Hua Li1, Qing-Gui Wu1,*, Jun Teng1,*, Chao-Jun Chen1,2

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.1, pp. 865-884, 2024, DOI:10.32604/cmes.2023.029927

    Abstract Collisions between a moving mass and an anti-collision device increase structural responses and threaten structural safety. An active mass damper (AMD) with stroke limitations is often used to avoid collisions. However, a stroke-limited AMD control system with a fixed limited area shortens the available AMD stroke and leads to significant control power. To solve this problem, the design approach with variable gain and limited area (VGLA) is proposed in this study. First, the boundary of variable-limited areas is calculated based on the real-time status of the moving mass. The variable gain (VG) expression at the variable limited area is deduced… More >

  • Open Access


    IRS Assisted UAV Communications against Proactive Eavesdropping in Mobile Edge Computing Networks

    Ying Zhang1,*, Weiming Niu2, Leibing Yan1

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.1, pp. 885-902, 2024, DOI:10.32604/cmes.2023.029234

    Abstract In this paper, we consider mobile edge computing (MEC) networks against proactive eavesdropping. To maximize the transmission rate, IRS assisted UAV communications are applied. We take the joint design of the trajectory of UAV, the transmitting beamforming of users, and the phase shift matrix of IRS. The original problem is strong non-convex and difficult to solve. We first propose two basic modes of the proactive eavesdropper, and obtain the closed-form solution for the boundary conditions of the two modes. Then we transform the original problem into an equivalent one and propose an alternating optimization (AO) based method to obtain a… More >

  • Open Access


    First Report of a Successful Development of Yam Hybrids (Dioscorea alata L.) from Lyophilized and Long-Term Stored Pollens

    Erick Malédon1, Elie Nudol1, Christophe Perrot1, Marie-Claire Gravillon1, Ronan Rivallan2,3, Denis Cornet2, Hâna Chair2,3, Komivi Dossa1,2,3,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.10, pp. 2861-2874, 2023, DOI:10.32604/phyton.2023.042397

    Abstract Various biological constraints including erratic and asynchronous flowering between male and female plants hinder successful hybrid development and genetic gains in greater yam breeding programs. Therefore, pollen storage has gained much attention to facilitate artificial pollinations and increase the genetic gains. This 4-year study aimed at developing a practical long-term pollen storage technique for the successful development of yam hybrids. Fresh pollens were collected from two Dioscorea alata males, then lyophilized (two lyophilization treatments were applied), followed by storage at room temperature (24°C–25°C) for 12 months. Moreover, the lyophilized and stored pollens were tested for viability by crossing with four… More >

  • Open Access


    Network biology: A promising approach for drug target identification against neurodevelopmental disorders


    BIOCELL, Vol.47, No.8, pp. 1675-1687, 2023, DOI:10.32604/biocell.2023.029624

    Abstract Biological entities are involved in complicated and complex connections; hence, discovering biological information using network biology ideas is critical. In the past few years, network biology has emerged as an integrative and systems-level approach for understanding and interpreting these complex interactions. Biological network analysis is one method for reducing enormous data sets to clinically useful knowledge for disease diagnosis, prognosis, and treatment. The network of biological entities can help us predict drug targets for several diseases. The drug targets identified through the systems biology approach help in targeting the essential biological pathways that contribute to the progression and development of… More >

  • Open Access


    Immunogenic cell death-related long noncoding RNA influences immunotherapy against lung adenocarcinoma


    Oncology Research, Vol.31, No.5, pp. 753-767, 2023, DOI:10.32604/or.2023.029287

    Abstract Lung adenocarcinoma (LUAD) is the leading cause of cancer-related deaths, accounting for over a million deaths worldwide annually. Immunogenic cell death (ICD) elicits an adaptive immune response. However, the role of ICD-related long noncoding RNAs (lncRNAs) in LUAD is unknown. In this study, we investigated the characteristics of the tumor microenvironment in LUAD, the prognostic significance of ICD-related lncRNAs, and the half-maximal inhibitory concentration (IC50) of possible chemotherapeutic drugs. We sorted prognostic lncRNAs using univariate Cox regression and constructed a risk signature based on them. We then confirmed the model’s accuracy and generated a nomogram. Additionally, we performed immune microenvironment… More > Graphic Abstract

    Immunogenic cell death-related long noncoding RNA influences immunotherapy against lung adenocarcinoma

  • Open Access


    An Innovative Technique for Constructing Highly Non-Linear Components of Block Cipher for Data Security against Cyber Attacks

    Abid Mahboob1, Muhammad Asif2, Rana Muhammad Zulqarnain3,*, Imran Siddique4, Hijaz Ahmad5, Sameh Askar6, Giovanni Pau7

    Computer Systems Science and Engineering, Vol.47, No.2, pp. 2547-2562, 2023, DOI:10.32604/csse.2023.040855

    Abstract The rapid advancement of data in web-based communication has created one of the biggest issues concerning the security of data carried over the internet from unauthorized access. To improve data security, modern cryptosystems use substitution-boxes. Nowadays, data privacy has become a key concern for consumers who transfer sensitive data from one place to another. To address these problems, many companies rely on cryptographic techniques to secure data from illegal activities and assaults. Among these cryptographic approaches, AES is a well-known algorithm that transforms plain text into cipher text by employing substitution box (S-box). The S-box disguises the relationship between cipher… More >

  • Open Access


    Ginsenoside Rg1 protects against ischemia-induced neuron damage by regulating the rno-miRNA-27a-3p/PPARγ axis


    BIOCELL, Vol.47, No.7, pp. 1583-1594, 2023, DOI:10.32604/biocell.2023.028016

    Abstract Background: A preliminary miRNA screening showed that expression levels of rno-miRNA-27a-3p were significantly increased in the serum and brain tissues of rats undergoing cerebral ischemia. In recent years, there is evidence of the protective capacity of the saponins extracted from panax ginseng and its primary active ingredient ginsenosideRg1oncerebral ischemic injury. Methods: Fetal rat neurons (FRNs) were cultured in glucose-and-serum-free medium and exposed to hypoxia to establish a cerebral ischemia model in vitro (oxygen and glucose deprivation model, OGD). Antioxidant indexes (CAT, SOD), inflammatory markers (MPO, TNF-α and IL-6), and the expression of apoptosis and proliferation associated proteins (NF kB-p65, Caspase… More >

  • Open Access


    Antibacterial Activity and Mechanisms of Ethanol Extracts from Scutellaria baicalensis Georgi and Magnolia officinalis against Phytophthora nicotianae

    Xu Gao, Ziqi Shen, Jinliang Xu, Min Fan, Qiang Li*

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 1987-1999, 2023, DOI:10.32604/phyton.2023.027318

    Abstract Phytophthora nicotianae causes substantial economic losses in most countries where tobacco is produced. At present, the control of P. nicotianae mainly depends on chemical methods, with considerable environmental and health issues. We investigated the effects of ethanol extracts from Scutellaria baicalensis Georgi (SBG) and Magnolia officinalis (MO). On mycelial growth, sporangium formation, and zoospore release of P. nicotianae. Both extracts inhibited the growth of P. nicotianae, with mycelial growth inhibition rates of 88.92% and 93.92%, respectively, at 40 mg/mL, and EC50 values of 5.39 and 5.74 mg/mL, respectively. The underlying mechanisms were the inhibition of sporangium formation, the reduction of… More >

  • Open Access


    Insecticidal Potential of α-Pinene and β-Caryophyllene against Myzus persicae and Their Impacts on Gene Expression

    Talha Ali Chohan1,*, Tahir Ali Chohan2,*, Muhammad Zahid Mumtaz1, Muhammad Waqar Alam3, Salah ud Din4, Iqra Naseer5, Ayesha Riaz1, Tayyeba Naseem1, Areeba Iftikhar6, Dur E. Najaf Ali1, Mubashir Hassan7, Hayssam M. Ali8

    Phyton-International Journal of Experimental Botany, Vol.92, No.7, pp. 1943-1954, 2023, DOI:10.32604/phyton.2023.026945

    Abstract Myzus persicae (M. persicae) is now considered a threat to agricultural crops due to economic losses. Numerous synthetic insecticides applied every year against M. persicae, are reported to be unsafe for environment, humans, and beneficial insects. Furthermore, several species of Myzus have been found to develop resistance due to over application of these insecticides. Therefore, it is required to find some novel insecticide that would be safe for the environment as well as for humans. In the current study, two major pure constituents α-pinene and β-caryophyllene were evaluated for their insecticidal potential against M. persicae using a fumigant toxicity assay.… More >

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