Gabriel Matheus Da Silva Batista, Lucas Pina Rodrigues, Andrey Jorge Serra^*

BIOCELL, Vol.49, No.10, pp. 1873-1885, 2025, DOI:10.32604/biocell.2025.067186 - 22 October 2025

Abstract Adipose-derived stem cells (ADSCs) therapy has emerged as a promising strategy for treating degenerative, inflammatory, and cardiometabolic diseases. In addition to their higher bioavailability in adipose tissue, ADSCs demonstrate superior activity in producing specific immune modulators and growth factors when compared to other stem cell types. The detrimental impact of heart failure (HF)—a condition that still lacks a fully effective therapy—has driven significant interest in the therapeutic potential of ADSCs. This interest is supported by robust evidence from experimental studies employing HF animal models. Accordingly, this review aims to explore the cardioprotective mechanisms through which More >

Prasanna Kottapalle^1,*, Tan Kuan Tak², Pravin Ramdas Kshirsagar³, Gopichand Ginnela⁴, Vijaya Krishna Akula⁵

CMC-Computers, Materials & Continua, Vol.84, No.2, pp. 3857-3892, 2025, DOI:10.32604/cmc.2025.065287 - 03 July 2025

Abstract Heart failure prediction is crucial as cardiovascular diseases become the leading cause of death worldwide, exacerbated by the COVID-19 pandemic. Age, cholesterol, and blood pressure datasets are becoming inadequate because they cannot capture the complexity of emerging health indicators. These high-dimensional and heterogeneous datasets make traditional machine learning methods difficult, and Skewness and other new biomarkers and psychosocial factors bias the model’s heart health prediction across diverse patient profiles. Modern medical datasets’ complexity and high dimensionality challenge traditional prediction models like Support Vector Machines and Decision Trees. Quantum approaches include QSVM, QkNN, QDT, and others.… More >

William H. Marshall V^1,2,*, Lydia K. Wright²

Congenital Heart Disease, Vol.19, No.4, pp. 419-433, 2024, DOI:10.32604/chd.2024.056608 - 31 October 2024

Abstract Heart failure (HF) is common in patients with congenital heart disease (CHD) and there are limited medical therapies. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are a proven medical therapy in patients with acquired HF, though data are limited in patients with CHD. The aim of this review is to summarize the current evidence for use of SGLT2i in patients with CHD and identify future directions for study. In available publications, SGLT2i in patients with CHD seem to be well tolerated, with similar side effect profile to patients with acquired HF. Improvement in functional capacity and natriuretic More >

Polin Rahman¹, Ahmed Rifat¹, MD. IftehadAmjad Chy¹, Mohammad Monirujjaman Khan^1,*, Mehedi Masud², Sultan Aljahdali²

Computer Systems Science and Engineering, Vol.44, No.1, pp. 757-775, 2023, DOI:10.32604/csse.2023.021469 - 01 June 2022

Abstract Heart failure is now widely spread throughout the world. Heart disease affects approximately 48% of the population. It is too expensive and also difficult to cure the disease. This research paper represents machine learning models to predict heart failure. The fundamental concept is to compare the correctness of various Machine Learning (ML) algorithms and boost algorithms to improve models’ accuracy for prediction. Some supervised algorithms like K-Nearest Neighbor (KNN), Support Vector Machine (SVM), Decision Trees (DT), Random Forest (RF), Logistic Regression (LR) are considered to achieve the best results. Some boosting algorithms like Extreme Gradient… More >

R. Sujatha¹, Jyotir Moy Chatterjee², NZ Jhanjhi³, Thamer A. Tabbakh⁴, Zahrah A. Almusaylim^5,*

Intelligent Automation & Soft Computing, Vol.32, No.1, pp. 115-129, 2022, DOI:10.32604/iasc.2022.019133 - 26 October 2021

Abstract Heart failure (HF) is an intercontinental pandemic influencing in any event 26 million individuals globally and is expanding in commonness. HF healthiness consumptions are extensive and will increment significantly with a maturing populace. As per the World Health Organization (WHO), Cardiovascular diseases (CVDs) are the major reason for all-inclusive death, taking an expected 17.9 million lives per year. CVDs are a class of issues of the heart, blood vessels and include coronary heart sickness, cerebrovascular illness, rheumatic heart malady, and various other conditions. In the medical care industry, a lot of information is as often… More >

Barry O’Callaghan¹, Jenny Zablah¹, Joseph Vettukattil², Daniel Levi^3,4, Morris Salem⁴, Allison Cabalka⁵, Jason Anderson⁶, Makram Ebeid⁶, Ryan Alexy⁷, Gareth J. Morgan^1,*

Congenital Heart Disease, Vol.17, No.1, pp. 107-116, 2022, DOI:10.32604/CHD.2022.018590 - 26 October 2021

Abstract Objectives: To detail the US multi-institutional experience with the Occlutech^© (Occlutech International AB, Helsingborg, Sweden) atrial flow regulator (AFR) in children and adults with acquired or congenital heart disease. Background: The creation of a long-term atrial communication is desirable in several cardiovascular disease phenotypes, most notably pulmonary arterial hypertension, disorders of increased left ventricular filling and increased cavopulmonary pressures in patients with a Fontan type circulation. Methods: Patients were identified for inclusion from the AFR device manufacturer database. Data was collected using a RedCap database following IRB approval. 8 weeks of follow up data was sought for… More >

Cheryl Raskind-Hood^1,*, Kashaine A. Gray^2,3, Jayne Morgan³, Wendy M. Book^4,*

Congenital Heart Disease, Vol.16, No.4, pp. 333-355, 2021, DOI:10.32604/CHD.2021.014384 - 19 April 2021

Abstract Early intervention to prevent premature mortality is vital for adults with congenital heart defects (CHD). Anatomic complexity and comorbid conditions are thought to contribute to CHD mortality. Since hypertension (HTN) and heart failure (HF) are the comorbid conditions among the most prevalent causes of death in the United States, and commonly accompany CHD, it is crucial to evaluate whether they are reliable predictors of mortality for adults with CHD (ACHD) independent of anatomic CHD complexity. A retrospective cross-sectional analysis of ACHD, aged 18–64, with concomitant HTN and/or HF and at least one health care encounter… More >

Yuwen Chen^{1, 2, 3, *}, Xiaolin Qin^{1, 3}, Lige Zhang^{1, 3}, Bin Yi⁴

CMC-Computers, Materials & Continua, Vol.65, No.1, pp. 495-510, 2020, DOI:10.32604/cmc.2020.011278 - 23 July 2020

Abstract The occurrence of perioperative heart failure will affect the quality of medical services and threaten the safety of patients. Existing methods depend on the judgment of doctors, the results are affected by many factors such as doctors’ knowledge and experience. The accuracy is difficult to guarantee and has a serious lag. In this paper, a mixture prediction model is proposed for perioperative adverse events of heart failure, which combined with the advantages of the Deep Pyramid Convolutional Neural Networks (DPCNN) and Extreme Gradient Boosting (XGBOOST). The DPCNN was used to automatically extract features from patient’s More >

Liesbeth van Dessel¹, Béatrice Santens², Els Troost², Pieter De Meester^2,3, Leen Roggen², Filip Rega^3,4, Bart Meyns^3,4, Bjorn Cools⁵, Marc Gewillig⁵, Philip Moons^6,7,8, Lukas Meier⁹, Werner Budts^2,3, Alexander Van De Bruaene^2,3,*

Congenital Heart Disease, Vol.15, No.2, pp. 69-78, 2020, DOI:10.32604/CHD.2020.011512 - 23 June 2020

Abstract Background: Left-to-right shunt in sinus venosus septal defect (SVSD) may affect resistive (pulmonary vascular resistance–PVR) and elastic (pulmonary artery compliance-PAC) pulmonary artery properties. This study aimed at evaluating (1) impact of age, (2) pulmonary hemodynamics, and (3) outcome in a large cohort of SVSD patients. Methods: This study included 136 patients with SVSD (median age at diagnosis 14 (IQR 5–48) years, 47% male) of which 87 underwent catheterization. Pressures were measured and cardiac output was evaluated using the Fick principle at diagnosis. PVR, PAC and their product (RC time) were calculated. Results: Surgical repair was performed in… More >

Christopher R. Broda

Congenital Heart Disease, Vol.14, No.3, pp. 487-490, 2019, DOI:10.1111/chd.12748

Abstract Heart failure is an emerging issue with important implications in adult patients with congenital heart disease. Practitioners with expertise in both adult congenital heart disease and heart failure are needed to manage this growing and often complex pop‐ ulation. In the United States, the optimal training pathway to enable practitioners to best care for these patients is ill‐defined. This article explores possibilities and issues that interested trainees may encounter during their training experience. More >