Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (1)
  • Open Access


    A Re-Parametrization-Based Bayesian Differential Analysis Algorithm for Gene Regulatory Networks Modeled with Structural Equation Models

    Yan Li1,2, Dayou Liu1,2, Yungang Zhu1,2, Jie Liu1,2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.124, No.1, pp. 303-313, 2020, DOI:10.32604/cmes.2020.09353

    Abstract Under different conditions, gene regulatory networks (GRNs) of the same gene set could be similar but different. The differential analysis of GRNs under different conditions is important for understanding condition-specific gene regulatory relationships. In a naive approach, existing GRN inference algorithms can be used to separately estimate two GRNs under different conditions and identify the differences between them. However, in this way, the similarities between the pairwise GRNs are not taken into account. Several joint differential analysis algorithms have been proposed recently, which were proved to outperform the naive approach apparently. In this paper, we… More >

Displaying 1-10 on page 1 of 1. Per Page