Rabindranath Bera^1,#, Yotaro Ochi^2,3, Ying-Jung Huang¹, Ming-Chung Kuo^1,4, Kenichi Yoshida⁵, Seishi Ogawa², Lee-Yung Shih^1,4,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070259 - 30 December 2025

Abstract Background: Breakpoint Cluster Region-Abelson (BCR::ABL1) fusion protein is essential in the pathogenesis of chronic myeloid leukemia (CML); however, the chronic-to-blast phase transformation remains elusive. We identified novel kinesin light chain 2 (KLC2) mutations in CML-myeloid blast phase patients. We aimed to examine the functional role of KLC2 mutations in leukemogenesis. Methods: To evaluate the biological role of KLC2 mutants (MT) in CML cells, we expressed KLC2-MT in different human CML cell lines harboring BCR::ABL1 and performed immunoblot, immunofluorescence, cell proliferation, differentiation, and apoptosis; Tyrosine kinase inhibitor (TKI)-drug activities; and clonogenic assays for in vitro functional analyses. We co-expressed KLC2-MT… More >

Chia-Hui Liu^*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-18, 2026, DOI:10.32604/cmc.2025.072887 - 09 December 2025

Abstract The Industrial Internet of Things (IIoT) has emerged as a cornerstone of Industry 4.0, enabling large-scale automation and data-driven decision-making across factories, supply chains, and critical infrastructures. However, the massive interconnection of resource-constrained devices also amplifies the risks of eavesdropping, data tampering, and device impersonation. While digital signatures are indispensable for ensuring authenticity and non-repudiation, conventional schemes such as RSA and ECC are vulnerable to quantum algorithms, jeopardizing long-term trust in IIoT deployments. This study proposes a lightweight, stateless, hash-based signature scheme that achieves post-quantum security while addressing the stringent efficiency demands of IIoT. The… More >

Mingming Huang¹, Yunfan Ye^1,*, Zhiping Cai²

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-17, 2026, DOI:10.32604/cmc.2025.072399 - 09 December 2025

Abstract As a fundamental component in computer vision, edges can be categorized into four types based on discontinuities in reflectance, illumination, surface normal, or depth. While deep CNNs have significantly advanced generic edge detection, real-time multi-class semantic edge detection under resource constraints remains challenging. To address this, we propose a lightweight framework based on PiDiNet that enables fine-grained semantic edge detection. Our model simultaneously predicts background and four edge categories from full-resolution inputs, balancing accuracy and efficiency. Key contributions include: a multi-channel output structure expanding binary edge prediction to five classes, supported by a deep supervision More >

Zhonghao Wang^1,2, Xin Liu^1,2,*, Changhua Yue³, Haiwen Yuan⁴

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-23, 2026, DOI:10.32604/cmc.2025.071813 - 09 December 2025

Abstract To address critical challenges in nighttime ship detection—high small-target missed detection (over 20%), insufficient lightweighting, and limited generalization due to scarce, low-quality datasets—this study proposes a systematic solution. First, a high-quality Night-Ships dataset is constructed via CycleGAN-based day-night transfer, combined with a dual-threshold cleaning strategy (Laplacian variance sharpness filtering and brightness-color deviation screening). Second, a Cross-stage Lightweight Fusion-You Only Look Once version 8 (CLF-YOLOv8) is proposed with key improvements: the Neck network is reconstructed by replacing Cross Stage Partial (CSP) structure with the Cross Stage Partial Multi-Scale Convolutional Block (CSP-MSCB) and integrating Bidirectional Feature Pyramid More >

Shaobo Kang, Mingzhi Yang^*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-23, 2026, DOI:10.32604/cmc.2025.071488 - 09 December 2025

Abstract Fabric defect detection plays a vital role in ensuring textile quality. However, traditional manual inspection methods are often inefficient and inaccurate. To overcome these limitations, we propose FD-YOLO, an enhanced lightweight detection model based on the YOLOv11n framework. The proposed model introduces the Bi-level Routing Attention (BRAttention) mechanism to enhance defect feature extraction, enabling more detailed feature representation. It proposes Deep Progressive Cross-Scale Fusion Neck (DPCSFNeck) to better capture small-scale defects and incorporates a Multi-Scale Dilated Residual (MSDR) module to strengthen multi-scale feature representation. Furthermore, a Shared Detail-Enhanced Lightweight Head (SDELHead) is employed to reduce More >

Jiajia Liu^1,*, Junyi Lin², Wenxiang Dong², Xuan Zhao², Jianhua Liu², Huiru Li³

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-19, 2026, DOI:10.32604/cmc.2025.071397 - 09 December 2025

Abstract Single Image Super-Resolution (SISR) seeks to reconstruct high-resolution (HR) images from low-resolution (LR) inputs, thereby enhancing visual fidelity and the perception of fine details. While Transformer-based models—such as SwinIR, Restormer, and HAT—have recently achieved impressive results in super-resolution tasks by capturing global contextual information, these methods often suffer from substantial computational and memory overhead, which limits their deployment on resource-constrained edge devices. To address these challenges, we propose a novel lightweight super-resolution network, termed Binary Attention-Guided Information Distillation (BAID), which integrates frequency-aware modeling with a binary attention mechanism to significantly reduce computational complexity and parameter… More >

Baixuan Han¹, Yueping Peng^1,*, Zecong Ye², Hexiang Hao¹, Xuekai Zhang¹, Wei Tang¹, Wenchao Kang¹, Qilong Li¹

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-31, 2026, DOI:10.32604/cmc.2025.071071 - 09 December 2025

Abstract Aiming at the problem of imbalance between detection accuracy and algorithm model lightweight in UAV aerial image target detection algorithm, a lightweight multi-category abnormal behavior detection algorithm based on improved YOLOv11n is designed. By integrating multi-head grouped self-attention mechanism and Partial-Conv, a two-way feature grouping fusion module (DFPF) was designed, which carried out effective channel segmentation and fusion strategies to reduce redundant calculations and memory access. C3K2 module was improved, and then unstructured pruning and feature distillation technology were used. The algorithm model is lightweight, and the feature extraction ability for airborne visual abnormal behavior… More >

Yuang Chen^1,2, Yong Li^1,*, Fang Lin^1,2, Shuhan Lv^1,2, Jiaze Jiang^1,2

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-18, 2026, DOI:10.32604/cmc.2025.070990 - 09 December 2025

Abstract Aiming at the problem of potential information noise introduced during the generation of ghost feature maps in GhostNet, this paper proposes a novel lightweight neural network model called ResghostNet. This model constructs the Resghost Module by combining residual connections and Adaptive-SE Blocks, which enhances the quality of generated feature maps through direct propagation of original input information and selection of important channels before cheap operations. Specifically, ResghostNet introduces residual connections on the basis of the Ghost Module to optimize the information flow, and designs a weight self-attention mechanism combined with SE blocks to enhance feature More >

Wen-Tsai Sung¹, Indra Griha Tofik Isa^2,3, Sung-Jung Hsiao^4,*

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-31, 2026, DOI:10.32604/cmc.2025.070922 - 09 December 2025

Abstract Mango is a plant with high economic value in the agricultural industry; thus, it is necessary to maximize the productivity performance of the mango plant, which can be done by implementing artificial intelligence. In this study, a lightweight object detection model will be developed that can detect mango plant conditions based on disease potential, so that it becomes an early detection warning system that has an impact on increasing agricultural productivity. The proposed lightweight model integrates YOLOv7-Tiny and the proposed modules, namely the C2S module. The C2S module consists of three sub-modules such as the… More >

Le Wang¹, Bing Xu^1,*, Peng Liu², En Yuan¹

CMC-Computers, Materials & Continua, Vol.86, No.2, pp. 1-14, 2026, DOI:10.32604/cmc.2025.070794 - 09 December 2025

Abstract Deep learning has been recognized as an effective method for indoor positioning. However, most existing real-valued neural networks (RVNNs) treat the two constituent components of complex-valued channel state information (CSI) as real-valued inputs, potentially discarding useful information embedded in the original CSI. In addition, existing positioning models generally face the contradiction between computational complexity and positioning accuracy. To address these issues, we combine graph neural network (GNN) with complex-valued neural network (CVNN) to construct a lightweight indoor positioning model named CGNet. CGNet employs complex-valued convolution operation to directly process the original CSI data, fully exploiting… More >