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  • Open Access

    REVIEW

    Multifunctional Carbonaceous Nanoreinforced Polymeric Nanofibers—Bridging Fundamental Aspects to Technological Resolves

    Ayesha Kausar*

    Journal of Polymer Materials, Vol.43, No.1, 2026, DOI:10.32604/jpm.2026.078233 - 03 April 2026

    Abstract Purpose of this novel review article is to unfold the current scientific worth of high performance polymer nanocomposite nanofibers, owing to growing scientific interests in this field. Accordingly, this state-of-the-art manuscript has been systematically categorized into distinct sections related to (i) fundamentals of carbonaceous nanoreinforcements, (ii) design-structure-property-performance aspects of different categories of polymer nanocomposite nanofibers (conducting polymers, thermoplastics, and thermosets with carbonaceous nanofillers (carbon nanotubes, graphene, fullerene), and then (iii) existing scientific worth (energy devices, electronics, space/defense, environmental sectors), future prospects, challenges, and conclusions. As per literature to date, polymer/carbonaceous nanocomposite nanofibers had myriad of advantageous physical… More > Graphic Abstract

    Multifunctional Carbonaceous Nanoreinforced Polymeric Nanofibers—Bridging Fundamental Aspects to Technological Resolves

  • Open Access

    ARTICLE

    Zein Membrane Barrier for Bone Guided Regeneration

    Cristiane Michele Alves de Oliveira1, Bruna Carolina Dorm1, Antonio José Felix Carvalho2, Deliane da Silva Cabral2, Flávia Aparecida Resende Nogueira1, Nádia Andrade Aleixo1, Mônica Rosas Costa Iemma1, Eliane Trovatti1,*

    Journal of Renewable Materials, Vol.14, No.3, 2026, DOI:10.32604/jrm.2025.02025-0166 - 25 March 2026

    Abstract Materials from natural sources have been studied to replace the conventional synthetic or animal-derived products as a safer alternative to be used in the healthcare field. In dentistry, guided bone regeneration (GBR) relies on barrier membranes, predominantly from animals or synthetic materials, to improve osteogenesis by avoiding undesired soft tissue cells from defect sites. In this study, membranes were prepared from zein, a corn-derived protein, using a simple extraction and casting method, followed by optional formaldehyde cross-linking to evaluate their behavior for application in GBR. The membranes were characterised by FTIR, DSC, TGA, tensile strength… More > Graphic Abstract

    Zein Membrane Barrier for Bone Guided Regeneration

  • Open Access

    REVIEW

    Recent Advances in Radiopharmaceuticals for Cancer Diagnosis and Therapy

    Ye Ri Han1,*, Sang Bong Lee2,3,*

    Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2026.075923 - 23 March 2026

    Abstract Radiopharmaceuticals deliver diagnostic or therapeutic radionuclides to disease sites with molecular precision. Over the past five years, clinical adoption has accelerated, led by U.S. Food and Drug Administration approvals of 177Lu-DOTA-TATE and 177Lu-PSMA-617 and their complementary Positron Emission Tomography agents (68Ga-DOTA-TATE, 68Ga-PSMA-11), which have established radiotheranostics as a pillar of oncology care. The new generation of agents couples optimized radionuclides (β, α, and Auger emitters) to antibodies, peptides, and small-molecule vectors that improve tumor uptake, residence time, and clearance profiles, thereby enhancing efficacy and safety. Beyond neuroendocrine tumors and prostate cancer, radiotheranostic strategies are advancing for diverse malignancies… More >

  • Open Access

    ARTICLE

    Sunitinib and Fenofibrate as Combination Therapy for MDR Glioblastoma: Insights from In Vitro and In Silico Studies

    Saad Alobid1,#, Hussam Albassam1,#, Tebyan O. Mirgany2, Faris Almutairi1, Mohammed Mufadhe Alanazi1, Ahmed H. Bakheit2, Hanadi H. Asiri2, Eram Eltahir3, Gamaleldin I. Harisa3,*

    Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2025.073371 - 23 March 2026

    Abstract Objective: Glioblastoma (GB) therapy is challenged by tumor heterogeneity and multidrug resistance (MDR), highlighting the need for effective therapies. This study aimed to explore the combined anticancer effects of Sunitinib (SNB) and Fenofibrate (FEN) on U87 cells. Methods: U87 cells were exposed to SNB, FEN, or their combination for 24 h, followed by evaluations of cell viability, migration, and clonogenic survival using MTT, scratch, and colony formation assays. Intracellular reactive oxygen species (ROS) were quantified via the 2, 7-dichlorofluorescein assay, while mitochondrial membrane potential (MMP) was assessed using JC-1 red/green fluorescence. Molecular docking was performed to… More > Graphic Abstract

    Sunitinib and Fenofibrate as Combination Therapy for MDR Glioblastoma: Insights from <i>In Vitro</i> and <i>In Silico</i> Studies

  • Open Access

    REVIEW

    Prostate specific membrane antigen (PSMA) as a biomarker in early and localized advanced prostate cancer: a narrative review

    Jonathon Carll1,2,3,*, Jacinta Bonaddio1, Dixon Woon1,4,5, Marlon Perera1,4,5,6, Nathan Lawrentschuk2,3,5,6, Thilakavathi Chengodu1,3

    Canadian Journal of Urology, Vol.33, No.1, pp. 21-34, 2026, DOI:10.32604/cju.2025.068908 - 28 February 2026

    Abstract Prostate-specific membrane antigen (PSMA) is a surface membrane antigen that is highly overexpressed in prostate cancer, with heterogenous expression throughout the natural history of the disease. This has generated significant interest as a potential biomarker for use in early diagnosis and treatment of prostate cancer. We reviewed the literature surrounding PSMA and its current clinical applications in diagnosing and managing early prostate cancer that is confined to the prostate and local lymph nodes. A search on PubMed, Medline, and Web of Science was performed using the following keywords: “PSMA”, “Prostate Specific Membrane Antigen”, “Prostate cancer”,… More >

  • Open Access

    ARTICLE

    Geometrically Nonlinear Analyses of Isotropic and Laminated Shells by a Hierarchical Quadrature Element Method

    Yingying Lan, Bo Liu*

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2026.075706 - 29 January 2026

    Abstract In this work, the Hierarchical Quadrature Element Method (HQEM) formulation of geometrically exact shells is proposed and applied for geometrically nonlinear analyses of both isotropic and laminated shells. The stress resultant formulation is developed within the HQEM framework, consequently significantly simplifying the computations of residual force and stiffness matrix. The present formulation inherently avoids shear and membrane locking, benefiting from its high-order approximation property. Furthermore, HQEM’s independent nodal distribution capability conveniently supports local p-refinement and flexibly facilitates mesh generation in various structural configurations through the combination of quadrilateral and triangular elements. Remarkably, in lateral buckling… More >

  • Open Access

    SHORT COMMUNICATION

    RNF213 Formed and Decorated Membrane-Based Structures in U-2 OS Cells

    TOSHIYUKI HABU*

    BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.071798 - 23 January 2026

    Abstract RING protein 213 (RNF213), the susceptibility gene for Moyamoya disease (MMD), possesses two active AAA+ ATPase (ATPases Associated with diverse cellular Activities) modules, a RING, and RNF213-ZNFX1 finger (RZ finger) domains. Several RNF213 variants have been reported in MMD patients, including the p.R4810K variant (rs112735431), which is a founder polymorphism associated with MMD in East Asia. To elucidate the function of RNF213 and its variant, we investigated the localization of RNF213 and the R4810K variant in this study. RNF213 induced circular hole structures near the nucleus, similar to lipid droplets (LDs), in U-2 OS cells. More >

  • Open Access

    ARTICLE

    Post-Norwood Extracorporeal Membrane Oxygenation—The Complex Interplay of Cardiopulmonary Bypass and Myocardial Ischemic Time

    Ryan G. McQueen1, Paulina M. Gutkin2, George M. Hoffman3, Ronald K. Woods4,*

    Congenital Heart Disease, Vol.20, No.6, pp. 683-692, 2025, DOI:10.32604/chd.2025.075838 - 10 February 2026

    Abstract Objective: The objective of this study was to understand intraoperative risk factors for post-Norwood extracorporeal membrane oxygenation (ECMO) in patients with hypoplastic left heart syndrome (HLHS). Methods: We conducted a retrospective, single-institution review of all patients with HLHS who underwent a Norwood procedure (nadir cardiopulmonary bypass temperature ≤ 22°C) over a 12-year period with quantitative and qualitative analysis. Results: Of 102 Norwood patients, 14 (13.7%) required ECMO. ECMO patients had longer median cardiopulmonary bypass (CPB) times (276 vs. 172 min, p < 0.001) and myocardial ischemic times (98.5 vs 83 min, p = 0.021). Longer CPB time was More >

  • Open Access

    ARTICLE

    Life Cycle Assessment of Solar-Assisted Post-Combustion CO2 Capture Using Hollow Fiber Membrane Contactors

    Lei Wang1, Hongyang Zhou2, Xiaofan Liu3, Junkun Mu2, Jinpeng Bi2, Youkang Jin2, Juan Ge2, Yuexia Lv2,4,*

    Frontiers in Heat and Mass Transfer, Vol.23, No.6, pp. 1811-1832, 2025, DOI:10.32604/fhmt.2025.071222 - 31 December 2025

    Abstract Membrane gas absorption and solar-assisted absorbent regeneration offer a sustainable approach to reduce the energy penalty of post-combustion CO2 capture. This study introduces a novel system integrating solar thermal energy with membrane gas absorption to capture CO2 from a 580 MWe pulverized coal power plant. The environmental impacts across six scenarios at varying solar fractions are evaluated via life cycle assessment. Results show a 7.61%–13.04% reduction in global warming potential compared to a steam-driven CO2 capture system. Electricity and steam consumption dominate the operational phase, contributing 15%–64% and 18%–61% to environmental impacts in non-TES scenarios, respectively. While More >

  • Open Access

    ARTICLE

    Performance Evaluation of Hierarchically Structured Superhydrophobic PVDF Membranes for Heavy Metals Removal via Membrane Distillation

    Pooja Yadav1,*, Ramin Farnood2, Vivek Kumar1,*

    Journal of Polymer Materials, Vol.42, No.4, pp. 1181-1197, 2025, DOI:10.32604/jpm.2025.072564 - 26 December 2025

    Abstract Heavy metal contamination in water sources is a widespread global concern, particularly in developing nations, with various treatment approaches under extensive scientific investigation. In the present study, we fabricated electrospun composite polyvinylidene fluoride (PVDF) nanofibrous membranes exhibiting hierarchical surface roughness and superhydrophobicity for the removal of heavy metal ions via vacuum membrane distillation (VMD) process. The membranes were prepared by incorporating optimized dosing of silica nanoparticles, followed by a two-step membrane modification approach. These membranes exhibited notable characteristics, including elevated water contact angle (152.8 ± 3.2°), increased liquid entry pressure (127 ± 6 kPa), and… More > Graphic Abstract

    Performance Evaluation of Hierarchically Structured Superhydrophobic PVDF Membranes for Heavy Metals Removal via Membrane Distillation

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