Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (3,433)
  • Open Access

    ARTICLE

    Shale Fracturability Graphic Template Based on Mixed Analytic Hierar-chy Process and Mutation Theory

    Sichen Li1,2, Dehua Liu1,2,*, Liang Cheng1,2, Pan Ma1,2

    Energy Engineering, Vol.121, No.7, pp. 1921-1943, 2024, DOI:10.32604/ee.2024.049906

    Abstract Due to the depletion of conventional energy reserves, there has been a global shift towards non-conventional energy sources. Shale oil and gas have emerged as key alternatives. These resources have dense and heterogeneous reservoirs, which require hydraulic fracturing to extract. This process depends on identifying optimal fracturing layers, also known as ‘sweet spots’. However, there is currently no uniform standard for locating these sweet spots. This paper presents a new model for evaluating fracturability that aims to address the current gap in the field. The model utilizes a hierarchical analysis approach and a mutation model, More >

  • Open Access

    REVIEW

    A Review of Basic Mechanical Properties of Bamboo Scrimber Based on Small-Scale Specimens

    Xin Xue1,2,3, Haitao Li1,2,3,*, Rodolfo Lorenzo4

    Journal of Renewable Materials, Vol.12, No.4, pp. 869-894, 2024, DOI:10.32604/jrm.2024.029602

    Abstract This review summarizes the existing knowledge about the mechanical properties of bamboo scrimber (BS) in literature. According to literature reviews, the strength of BS under different load modes is affected by a series of factors, such as the type of original bamboo, growth position, resin content, treatment method and density. Therefore, different production processes can be adopted according to different requirements, and bamboo scrimbers can also be classified accordingly. In addition, this review summarizes the changes in different factors considered by scholars in the research on the mechanical properties of BS, so that readers can More > Graphic Abstract

    A Review of Basic Mechanical Properties of Bamboo Scrimber Based on Small-Scale Specimens

  • Open Access

    ARTICLE

    Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor

    Dina Polosukhina*, Harold D. Love*†, Harold L. Moses‡§¶#, Ethan Lee**††, Roy Zent†§**‡‡, Peter E. Clark*‡

    Oncology Research, Vol.25, No.9, pp. 1653-1664, 2017, DOI:10.3727/096504017X14992942781895

    Abstract Wilms tumor (WT) is the most common renal malignancy in children and the fourth most common pediatric solid malignancy in the US. Although the mechanisms underlying the WT biology are complex, these tumors most often demonstrate activation of the canonical Wnt/β-catenin pathway. We and others have shown that constitutive activation of β-catenin restricted to the renal epithelium is sufficient to induce primitive renal epithelial tumors, which resemble human WT. Here we demonstrate that pharmacologic inhibition of β-catenin gene transcription with pyrvinium inhibits tumor growth and metastatic progression in a murine model of WT. Cellular invasion More >

  • Open Access

    ARTICLE

    Targeting CD47 Enhances the Efficacy of Anti-PD-1 and CTLA-4 in an Esophageal Squamous Cell Cancer Preclinical Model

    Hua Tao, Pudong Qian, Feijiang Wang, Hongliang Yu, Yesong Guo

    Oncology Research, Vol.25, No.9, pp. 1579-1587, 2017, DOI:10.3727/096504017X14900505020895

    Abstract Esophageal squamous cell cancer is a highly aggressive cancer with a dismal 5-year survival rate. CD47 is a cell transmembrane protein that is involved in cell apoptosis, proliferation, adhesion, migration, and antigen presentation in the immune system. By interacting with signal regulatory protein-a expressed in antigenpresenting cells (APCs), CD47 acts as an antiphagocytic mechanism to inhibit APC-dependent antigen presentation. Overexpression of CD47 was found in various types of cancer. However, its role in esophageal squamous cell cancer is not yet clear. Anti-CD47 is an antagonist of CD47 signaling pathways by competing with its ligand. In… More >

  • Open Access

    ARTICLE

    Potentially Suitable Area and Change Trends of Tulipa iliensis under Climate Change

    Douwen Qin1,2, Weiqiang Liu1,2, Jiting Tian1,2, Xiuting Ju1,2,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 981-1005, 2024, DOI:10.32604/phyton.2024.049668

    Abstract Tulipa iliensis, as a wild plant resource, possesses high ornamental value and can provide abundant parental materials for tulip breeding. The objective of this research was to forecast the worldwide geographical spread of Tulipa iliensis by considering bioclimatic, soil, and topographic variables, the findings of this research can act as a benchmark for the conservation, management, and utilization of Tulipa iliensis as a wild plant resource. Research results indicate that all 12 models have an area under curve (AUC) of the receiver operating characteristic curve (ROC) values greater than 0.968 for the paleoclimatic, current, and future climate scenarios,… More >

  • Open Access

    ARTICLE

    CD103+ Cell Growth Factor Flt3L Enhances the Efficacy of Immune Checkpoint Blockades in Murine Glioblastoma Model

    Xiaolin Miao*1, Yiqi Chen*1, Ke Hao†1, Meiqin Zheng, Bingyu Chen, Kaiqiang Li, Ying Wang, Wei Zhang§, Yu Zhang§, Xiaozhou Mou§, Shanshan Jiang, Zhen Wang‡§

    Oncology Research, Vol.26, No.2, pp. 173-182, 2018, DOI:10.3727/096504017X14841698396865

    Abstract Glioblastoma is a lethal disease featuring a high proliferation of tumor cells, excessive angiogenesis, and heavy drug resistance. The overall survival of glioblastoma patients has been dismal, even with an intensive standard of care. Recent advances in immune checkpoint blockades are changing the treatment of cancers. However, the efficacy of immune checkpoint blockades in glioblastoma is still unclear. Here we investigated the roles of CD103+ cells in regulating the effect of immune checkpoint blockades in glioblastoma mouse models. Our findings indicated that the murine glioblastoma model was not sensitive to immune checkpoint blockades. Flt3L, a growth More >

  • Open Access

    ARTICLE

    Highly Differentiated Target Detection under Extremely Low-Light Conditions Based on Improved YOLOX Model

    Haijian Shao1,2,*, Suqin Lei1, Chenxu Yan3, Xing Deng1, Yunsong Qi1

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1507-1537, 2024, DOI:10.32604/cmes.2024.050140

    Abstract This paper expounds upon a novel target detection methodology distinguished by its elevated discriminatory efficacy, specifically tailored for environments characterized by markedly low luminance levels. Conventional methodologies struggle with the challenges posed by luminosity fluctuations, especially in settings characterized by diminished radiance, further exacerbated by the utilization of suboptimal imaging instrumentation. The envisioned approach mandates a departure from the conventional YOLOX model, which exhibits inadequacies in mitigating these challenges. To enhance the efficacy of this approach in low-light conditions, the dehazing algorithm undergoes refinement, effecting a discerning regulation of the transmission rate at the pixel… More > Graphic Abstract

    Highly Differentiated Target Detection under Extremely Low-Light Conditions Based on Improved YOLOX Model

  • Open Access

    ARTICLE

    Sleep Posture Classification Using RGB and Thermal Cameras Based on Deep Learning Model

    Awais Khan1, Chomyong Kim2, Jung-Yeon Kim2, Ahsan Aziz1, Yunyoung Nam3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1729-1755, 2024, DOI:10.32604/cmes.2024.049618

    Abstract Sleep posture surveillance is crucial for patient comfort, yet current systems face difficulties in providing comprehensive studies due to the obstruction caused by blankets. Precise posture assessment remains challenging because of the complex nature of the human body and variations in sleep patterns. Consequently, this study introduces an innovative method utilizing RGB and thermal cameras for comprehensive posture classification, thereby enhancing the analysis of body position and comfort. This method begins by capturing a dataset of sleep postures in the form of videos using RGB and thermal cameras, which depict six commonly adopted postures: supine,… More > Graphic Abstract

    Sleep Posture Classification Using RGB and Thermal Cameras Based on Deep Learning Model

  • Open Access

    ARTICLE

    Predicting the Mechanical Behavior of a Bioinspired Nanocomposite through Machine Learning

    Xingzi Yang1, Wei Gao2, Xiaodu Wang1, Xiaowei Zeng1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1299-1313, 2024, DOI:10.32604/cmes.2024.049371

    Abstract The bioinspired nacre or bone structure represents a remarkable example of tough, strong, lightweight, and multifunctional structures in biological materials that can be an inspiration to design bioinspired high-performance materials. The bioinspired structure consists of hard grains and soft material interfaces. While the material interface has a very low volume percentage, its property has the ability to determine the bulk material response. Machine learning technology nowadays is widely used in material science. A machine learning model was utilized to predict the material response based on the material interface properties in a bioinspired nanocomposite. This model More >

  • Open Access

    REVIEW

    Phase-Field Simulation of Sintering Process: A Review

    Ming Xue, Min Yi*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.2, pp. 1165-1204, 2024, DOI:10.32604/cmes.2024.049367

    Abstract Sintering, a well-established technique in powder metallurgy, plays a critical role in the processing of high melting point materials. A comprehensive understanding of structural changes during the sintering process is essential for effective product assessment. The phase-field method stands out for its unique ability to simulate these structural transformations. Despite its widespread application, there is a notable absence of literature reviews focused on its usage in sintering simulations. Therefore, this paper addresses this gap by reviewing the latest advancements in phase-field sintering models, covering approaches based on energy, grand potential, and entropy increase. The characteristics More >

Displaying 1-10 on page 1 of 3433. Per Page