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Search Results (19)
  • Open Access

    ARTICLE

    Longitudinal Health-Related Quality of Life Assessment in Children with Congenital Heart Disease

    Angeles Fuertes-Moure1, Michael Meyer2,3, Anna-Luisa Häcker2,3, Barbara Reiner2,3, Leon Brudy3, Sonia Pértega-Diaz4, Renate Oberhoffer2,3, Peter Ewert2, Jan Müller2,3,*

    Congenital Heart Disease, Vol.15, No.4, pp. 217-227, 2020, DOI:10.32604/CHD.2020.011771 - 07 September 2020

    Abstract Objective: Health-related quality of life (HRQoL) has become an important outcome measure for patients with congenital heart disease (CHD). The aim of this study was to evaluate the natural course of HRQoL from longitudinal assessment in children with CHD. Patients and Methods: From July 2014 to February 2020 this longitudinal study recruited 317 children with CHD (113 girls, 35.6%) aged 6 to 18 years (11.6 ± 2.9 years). HRQoL was assessed with the generic, self-reported and age-adapted KINDL® questionnaire. During a mean follow-up period of 2.2 ± 1.3 years, 195 patients had one HRQoL reassessment, 70 two,… More >

  • Open Access

    ARTICLE

    Trajectory of right ventricular indices is an early predictor of outcomes in hypoplastic left heart syndrome

    Andrew S. Kim1, Colleen M. Witzenburg2, Mark Conaway3, Jeffrey E. Vergales1, Jeffrey W. Holmes2,4, Thomas J. L’Ecuyer1, Peter N. Dean1

    Congenital Heart Disease, Vol.14, No.6, pp. 1185-1192, 2019, DOI:10.1111/chd.12834

    Abstract Background: Children with hypoplastic left heart syndrome (HLHS) have risk for mortality and/or transplantation. Previous studies have associated right ventricular (RV) indices in a single echocardiogram with survival, but none have related serial measurements to outcomes. This study sought to determine whether the trajectory of RV indices in the first year of life was associated with transplant‐free survival to stage 3 palliation (S3P).
    Methods: HLHS patients at a single center who underwent stage 1 palliation (S1P) between 2000 and 2015 were reviewed. Echocardiographic indices of RV size and function were obtained before and following S1P and stage… More >

  • Open Access

    ARTICLE

    Serial assessment of postoperative ventricular mechanics in young children with tetralogy of Fallot: Comparison of transannular patch and valve‐sparing repair

    Vidhya Annavajjhala1, Rajesh Punn1, Theresa A. Tacy1, Frank L. Hanley2, Doff B. McElhinney2

    Congenital Heart Disease, Vol.14, No.5, pp. 691-699, 2019, DOI:10.1111/chd.12772

    Abstract Background: Little is known about the early time course of biventricular function and mechanics after tetralogy of Fallot (TOF) repair. We sought to evaluate and describe the evolution of the right ventricle (RV) after TOF repair in young infants and children using conventional echocardiographic parameters and global longitudinal strain (GLS).
    Methods: A retrospective review was performed of all patients with TOF and pulmo‐ nary stenosis who underwent repair from January 2002 to September 2015 and had at least 3 serial postsurgical echocardiograms spanning from infancy to early child‐ hood (<8 years). Student’s t test was performed to… More >

  • Open Access

    ABSTRACT

    Mass Transport of LDL in Stenotic Right Coronary Arteries

    Biyue Liu1,*, Dalin Tang2

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 25-26, 2019, DOI:10.32604/mcb.2019.06825

    Abstract The blood flow and mass transport pattern of low-density lipoprotein (LDL) in a right coronary artery with two stenoses are studied. Computations were carried out under physiological conditions. Our results show a strong correlation between wall shear stress (WSS) and distribution patterns of LDL. More >

  • Open Access

    ARTICLE

    Outage Capacity Analysis for Cognitive Non-Orthogonal Multiple Access Downlink Transmissions Systems in the Presence of Channel Estimation Error

    Yinghua Zhang1,2, Yanfang Dong2, Lei Wang1, Jian Liu1,*, Yunfeng Peng1, Jim Feng3

    CMC-Computers, Materials & Continua, Vol.60, No.1, pp. 379-393, 2019, DOI:10.32604/cmc.2019.05790

    Abstract In this paper, we propose a downlink cognitive non-orthogonal multiple access (NOMA) network, where the secondary users (SUs) operate in underlay mode. In the network, secondary transmitter employs NOMA signaling for downlink transmission, and the primary user (PU) is interfered by the transmission from SU. The expressions for the outage probabilities are derived in closed-form for both primary and secondary users in the presence of channel estimation error. Numerical simulation results show that the channel estimation error and the inter-network interference cause degradation of the downlink outage performance. Also the power allocation and the location More >

  • Open Access

    ARTICLE

    Quantum Homomorphic Signature with Repeatable Verification

    Tao Shang1,*, Zhuang Pei2, Ranyiliu Chen3, Jianwei Liu1

    CMC-Computers, Materials & Continua, Vol.59, No.1, pp. 149-165, 2019, DOI:10.32604/cmc.2019.05360

    Abstract In January 2015, the first quantum homomorphic signature scheme was proposed creatively. However, only one verifier is allowed to verify a signature once in this scheme. In order to support repeatable verification for general scenario, we propose a new quantum homomorphic signature scheme with repeatable verification by introducing serial verification model and parallel verification model. Serial verification model solves the problem of signature verification by combining key distribution and Bell measurement. Parallel verification model solves the problem of signature duplication by logically treating one particle of an EPR pair as a quantum signature and physically More >

  • Open Access

    ARTICLE

    Serial cardiac MRIs in adult Fontan patients detect progressive hepatic enlargement and congestion

    Matthew J. Lewis1, Elizabeth Hecht2, Jonathan Ginns1, Joshua Benton2, Martin Prince2, Marlon S. Rosenbaum1

    Congenital Heart Disease, Vol.12, No.2, pp. 153-158, 2017, DOI:10.1111/chd.12422

    Abstract Background: The progression of hepatic disease in adult Fontan patients is not well understood. They reviewed the experience with serial cardiac MRIs (CMR) in adult Fontan patients to determine if hepatic anatomic markers of prolonged Fontan exposure were present and if clinical predictors of progressive hepatic congestion could be identified.
    Methods and Results: A retrospective cohort study of all adult Fontan patients who had undergone at least two CMRs was performed. Hepatic dimensions, inferior vena cava (IVC) size, right hepatic vein (RHV) size and spleen diameter were determined from images acquired at the time of clinically guided… More >

  • Open Access

    ARTICLE

    A High-order Coupled Compact Integrated RBF Approximation Based Domain Decomposition Algorithm for Second-order Differential Problems

    C.M.T. Tien1, N. Pham-Sy1, N. Mai-Duy1, C.-D. Tran1, T. Tran-Cong1

    CMES-Computer Modeling in Engineering & Sciences, Vol.104, No.4, pp. 251-304, 2015, DOI:10.3970/cmes.2015.104.251

    Abstract This paper presents a high-order coupled compact integrated RBF (CC IRBF) approximation based domain decomposition (DD) algorithm for the discretisation of second-order differential problems. Several Schwarz DD algorithms, including one-level additive/ multiplicative and two-level additive/ multiplicative/ hybrid, are employed. The CCIRBF based DD algorithms are analysed with different mesh sizes, numbers of subdomains and overlap sizes for Poisson problems. Our convergence analysis shows that the CCIRBF two-level multiplicative version is the most effective algorithm among various schemes employed here. Especially, the present CCIRBF two-level method converges quite rapidly even when the domain is divided into… More >

  • Open Access

    ARTICLE

    Patient-Specific Carotid Plaque Progression Simulation Using 3D Meshless Generalized Finite Difference Models with Fluid-Structure Interactions Based on Serial In Vivo MRI Data

    Chun Yang1,2, Dalin Tang2, Satya Atluri3

    CMES-Computer Modeling in Engineering & Sciences, Vol.72, No.1, pp. 53-78, 2011, DOI:10.3970/cmes.2011.072.053

    Abstract Previously, we introduced a computational procedure based on three-dimensional meshless generalized finite difference (MGFD) method and serial magnetic resonance imaging (MRI) data to quantify patient-specific carotid atherosclerotic plaque growth functions and simulate plaque progression. Structure-only models were used in our previous report. In this paper, fluid-stricture interaction (FSI) was added to improve on prediction accuracy. One participating patient was scanned three times (T1, T2, and T3, at intervals of about 18 months) to obtain plaque progression data. Blood flow was assumed to laminar, Newtonian, viscous and incompressible. The Navier-Stokes equations with arbitrary Lagrangian-Eulerian (ALE) formulation… More >

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