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  • Open Access


    Exploring the attenuation mechanisms of Dalbergia odorifera leaves extract on cerebral ischemia-reperfusion based on weighted gene co-expression network analysis


    BIOCELL, Vol.47, No.7, pp. 1611-1622, 2023, DOI:10.32604/biocell.2023.028684

    Abstract Background: The attenuation function of Dalbergia odorifera leaves on cerebral ischemia-reperfusion (I/R) is little known. The candidate targets for the Chinese herb were extracted from brain tissues through the high-affinity chromatography. The molecular mechanism of D. odorifera leaves on cerebral I/R was investigated. Methods: Serial affinity chromatography based on D. odorifera leaves extract (DLE) affinity matrices were applied to find specific binding proteins in the brain tissues implemented on C57BL/6 mice by intraluminal middle cerebral artery occlusion for 1 h and reperfusion for 24 h. Specific binding proteins were subjected to mass-spectrometry to search for the differentially expressed proteins between… More >

  • Open Access


    The Effects of Job Insecurity, Emotional Exhaustion, and Met Expectations on Hotel Employees’ Pro-Environmental Behaviors: Test of a Serial Mediation Model

    Osman M. Karatepe1,*, Raheleh Hassannia1, Tuna Karatepe1, Constanţa Enea2, Hamed Rezapouraghdam1

    International Journal of Mental Health Promotion, Vol.25, No.2, pp. 287-307, 2023, DOI:10.32604/ijmhp.2022.025706

    Abstract There are a plethora of empirical pieces about employees’ pro-environmental behaviors. However, the extant literature has either ignored or not fully examined various factors (e.g., negative or positive non-green workplace factors) that might affect employees’ pro-environmental behaviors. Realizing these voids, the present paper proposes and tests a serial mediation model that examines the interrelationships of job insecurity, emotional exhaustion, met expectations, and proactive pro-environmental behavior. We used data gathered from hotel customer-contact employees with a time lag of one week and their direct supervisors in China. After presenting support for the psychometric properties of the measures via confirmatory analysis in… More >

  • Open Access


    Application of Time Serial Model in Water Quality Predicting

    Jiang Wu1, Jianjun Zhang1, Wenwu Tan1, Hao Lan1,*, Sirao Zhang1, Ke Xiao2, Li Wang2, Haijun Lin1, Guang Sun3, Peng Guo4

    CMC-Computers, Materials & Continua, Vol.74, No.1, pp. 67-82, 2023, DOI:10.32604/cmc.2023.030703

    Abstract Water resources are an indispensable and valuable resource for human survival and development. Water quality predicting plays an important role in the protection and development of water resources. It is difficult to predict water quality due to its random and trend changes. Therefore, a method of predicting water quality which combines Auto Regressive Integrated Moving Average (ARIMA) and clustering model was proposed in this paper. By taking the water quality monitoring data of a certain river basin as a sample, the water quality Total Phosphorus (TP) index was selected as the prediction object. Firstly, the sample data was cleaned, stationary… More >

  • Open Access


    AAP4All: An Adaptive Auto Parallelization of Serial Code for HPC Systems

    M. Usman Ashraf1,*, Fathy Alburaei Eassa2, Leon J. Osterweil3, Aiiad Ahmad Albeshri2, Abdullah Algarni2, Iqra Ilyas4

    Intelligent Automation & Soft Computing, Vol.30, No.2, pp. 615-639, 2021, DOI:10.32604/iasc.2021.019044

    Abstract High Performance Computing (HPC) technologies are emphasizing to increase the system performance across many disciplines. The primary challenge in HPC systems is how to achieve massive performance by minimum power consumption. However, the modern HPC systems are configured by adding the powerful and energy efficient multi-cores/many-cores parallel computing devices such as GPUs, MIC, and FPGA etc. Due to increasing the complexity of one chip many-cores/multi-cores systems, only well-balanced and optimized parallel programming technique is the solution to provide substantial increase in performance under power consumption limitations. Conventionally, the researchers face various barriers while parallelizing their serial code because they don’t… More >

  • Open Access


    Low Complexity Decoding Algorithm for Uplink SCMA Based on Aerial Spherical Decoding

    Xiaohong Ji1, Junjun Du1, Guoqing Jia1,*, Weidong Fang2,3

    Intelligent Automation & Soft Computing, Vol.27, No.3, pp. 737-746, 2021, DOI:10.32604/iasc.2021.013009

    Abstract As a new non-orthogonal multiple access technology for 5G massive machine type communication scenario, the sparse code multiple access (SCMA) has greatly improved the spectrum efficiency due to the high connection density. SCMA combines QAM (Quadrature Amplitude Modulation) modulation and sparse spreading into a codebook set to obtain forming gain. The user binary bit data is directly mapped into multi-dimensional codewords in the transmitter. The receiver uses the message passing algorithm (MPA) for multi-user detection to achieve efficient decoding. However, MPA is a good solution for SCMA, though its high complexity limits the application in practical systems. In order to… More >

  • Open Access


    Longitudinal Health-Related Quality of Life Assessment in Children with Congenital Heart Disease

    Angeles Fuertes-Moure1, Michael Meyer2,3, Anna-Luisa Häcker2,3, Barbara Reiner2,3, Leon Brudy3, Sonia Pértega-Diaz4, Renate Oberhoffer2,3, Peter Ewert2, Jan Müller2,3,*

    Congenital Heart Disease, Vol.15, No.4, pp. 217-227, 2020, DOI:10.32604/CHD.2020.011771

    Abstract Objective: Health-related quality of life (HRQoL) has become an important outcome measure for patients with congenital heart disease (CHD). The aim of this study was to evaluate the natural course of HRQoL from longitudinal assessment in children with CHD. Patients and Methods: From July 2014 to February 2020 this longitudinal study recruited 317 children with CHD (113 girls, 35.6%) aged 6 to 18 years (11.6 ± 2.9 years). HRQoL was assessed with the generic, self-reported and age-adapted KINDL® questionnaire. During a mean follow-up period of 2.2 ± 1.3 years, 195 patients had one HRQoL reassessment, 70 two, 40 three and… More >

  • Open Access


    Serial cardiac MRIs in adult Fontan patients detect progressive hepatic enlargement and congestion

    Matthew J. Lewis1, Elizabeth Hecht2, Jonathan Ginns1, Joshua Benton2, Martin Prince2, Marlon S. Rosenbaum1

    Congenital Heart Disease, Vol.12, No.2, pp. 153-158, 2017, DOI:10.1111/chd.12422

    Abstract Background: The progression of hepatic disease in adult Fontan patients is not well understood. They reviewed the experience with serial cardiac MRIs (CMR) in adult Fontan patients to determine if hepatic anatomic markers of prolonged Fontan exposure were present and if clinical predictors of progressive hepatic congestion could be identified.
    Methods and Results: A retrospective cohort study of all adult Fontan patients who had undergone at least two CMRs was performed. Hepatic dimensions, inferior vena cava (IVC) size, right hepatic vein (RHV) size and spleen diameter were determined from images acquired at the time of clinically guided CMR. Two radiologists… More >

  • Open Access


    Trajectory of right ventricular indices is an early predictor of outcomes in hypoplastic left heart syndrome

    Andrew S. Kim1, Colleen M. Witzenburg2, Mark Conaway3, Jeffrey E. Vergales1, Jeffrey W. Holmes2,4, Thomas J. L’Ecuyer1, Peter N. Dean1

    Congenital Heart Disease, Vol.14, No.6, pp. 1185-1192, 2019, DOI:10.1111/chd.12834

    Abstract Background: Children with hypoplastic left heart syndrome (HLHS) have risk for mortality and/or transplantation. Previous studies have associated right ventricular (RV) indices in a single echocardiogram with survival, but none have related serial measurements to outcomes. This study sought to determine whether the trajectory of RV indices in the first year of life was associated with transplant‐free survival to stage 3 palliation (S3P).
    Methods: HLHS patients at a single center who underwent stage 1 palliation (S1P) between 2000 and 2015 were reviewed. Echocardiographic indices of RV size and function were obtained before and following S1P and stage 2 palliation (S2P).… More >

  • Open Access


    Serial assessment of postoperative ventricular mechanics in young children with tetralogy of Fallot: Comparison of transannular patch and valve‐sparing repair

    Vidhya Annavajjhala1, Rajesh Punn1, Theresa A. Tacy1, Frank L. Hanley2, Doff B. McElhinney2

    Congenital Heart Disease, Vol.14, No.5, pp. 691-699, 2019, DOI:10.1111/chd.12772

    Abstract Background: Little is known about the early time course of biventricular function and mechanics after tetralogy of Fallot (TOF) repair. We sought to evaluate and describe the evolution of the right ventricle (RV) after TOF repair in young infants and children using conventional echocardiographic parameters and global longitudinal strain (GLS).
    Methods: A retrospective review was performed of all patients with TOF and pulmo‐ nary stenosis who underwent repair from January 2002 to September 2015 and had at least 3 serial postsurgical echocardiograms spanning from infancy to early child‐ hood (<8 years). Student’s t test was performed to compare patients who… More >

  • Open Access


    Mass Transport of LDL in Stenotic Right Coronary Arteries

    Biyue Liu1,*, Dalin Tang2

    Molecular & Cellular Biomechanics, Vol.16, Suppl.2, pp. 25-26, 2019, DOI:10.32604/mcb.2019.06825

    Abstract The blood flow and mass transport pattern of low-density lipoprotein (LDL) in a right coronary artery with two stenoses are studied. Computations were carried out under physiological conditions. Our results show a strong correlation between wall shear stress (WSS) and distribution patterns of LDL. More >

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