LINGYAN LV^1,2,#, JING ZHAO^1,2,#, XUAN WANG^1,2, LIUYAN XU^1,2, YINGYI FAN², CHUNHUI WANG³, HONGQIAO FAN^4,5,*, XIAOHUA PEI^5,*

BIOCELL, Vol.47, No.9, pp. 1977-1994, 2023, DOI:10.32604/biocell.2023.030742

Abstract Background: The development and prognosis of breast cancer are intricately linked to psychological stress. In addition, depression is the most common psychological comorbidity among breast cancer survivors, and reportedly, Fang-Xia-Dihuang decoction (FXDH) can effectively manage depression in such patients. However, its pharmacological and molecular mechanisms remain obscure. Methods: Public databases were used for obtaining active components and related targets. Main active components were further verified by ultra-high-performance liquid chromatography-high-resolution mass spectrometry (UPLC-HRMS). Protein–protein interaction and enrichment analyses were taken to predict potential hub targets and related pathways. Molecule docking was used to understand the interactions between main compounds and hub… More >

Huizhen Liu^1,2, Duanying Wan³, Meng Wang³, Zheming Zhu³, Liyun Yang^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.1, pp. 349-368, 2024, DOI:10.32604/cmes.2023.028197

Abstract Stress waves affect the stress field at the crack tip and dominate the dynamic crack propagation. Therefore, evaluating the influence of blasting stress waves on the crack propagation behavior and the mechanical characteristics of crack propagation is of great significance for engineering blasting. In this study, ANSYS/LS-DYNA was used for blasting numerical simulation, in which the propagation characteristics of blasting stress waves and stress field distribution at the crack tip were closely observed. Moreover, ABAQUS was applied for simulating the crack propagation path and calculating dynamic stress intensity factors (DSIFs). The universal function was calculated by the fractal method. The… More >

Liang Yi^1,*, Wen Gang¹, Nenggui Pan², Wangui Wang¹, Shengshuai Mo¹

FDMP-Fluid Dynamics & Materials Processing, Vol.19, No.11, pp. 2777-2790, 2023, DOI:10.32604/fdmp.2023.021907

Abstract The development of thermal stress in the exhaust manifold of a gasoline engine is considered. The problem is addresses in the frame of a combined approach where fluid and structure are coupled using the GT-POWER and STAR-CCM+ software. First, the external characteristic curve of the engine is compared with a one-dimensional simulation model, then the parameters of the model are modified until the curve matches the available experimental values. GT-POWER is then used to transfer the inlet boundary data under transient conditions to STAR-CCM+ in real-time. The temperature profiles of the inner and outer walls of the exhaust manifold are… More >

Muhammad Younis¹, Nudrat Aisha Akram^1,*, Arafat Abdel Hamed Abdel Latef^2,*, Muhammad Ashraf³

Phyton-International Journal of Experimental Botany, Vol.92, No.10, pp. 2761-2784, 2023, DOI:10.32604/phyton.2023.028801

Abstract To counteract the effects of drought stress, scientists have adopted several approaches including the use of different chemicals both inorganic and organic, which is contemplated as a highly efficient and cost-effective shot-gun approach. Ascorbic acid (AsA) is a potential organic substance, which widely occurs in plants, and is considered to be an effective antioxidant to counteract reactive oxygen species (ROS). Thus, a pot experiment was performed to assess the relative mitigating impacts of synthetic AsA and naturally occurring AsA in the form of lemon juice (LJ) and orange juice (OJ) on two cultivars of okra (Abelmoschus esculentus L.) namely Sabz… More >

Yanlei Xu, Xue Cong, Yuting Zhai, Zhiyuan Gao, Helong Yu^*

Intelligent Automation & Soft Computing, Vol.37, No.3, pp. 3019-3037, 2023, DOI:10.32604/iasc.2023.040330

Abstract To solve inefficient water stress classification of spinach seedlings under complex background, this study proposed an automatic classification method for the water stress level of spinach seedlings based on the N-MobileNetXt (NCAM+MobileNetXt) network. Firstly, this study reconstructed the Sandglass Block to effectively increase the model accuracy; secondly, this study introduced the group convolution module and a two-dimensional adaptive average pool, which can significantly compress the model parameters and enhance the model robustness separately; finally, this study innovatively proposed the Normalization-based Channel Attention Module (NCAM) to enhance the image features obviously. The experimental results showed that the classification accuracy of N-MobileNetXt… More >

Jinyu Gu¹, Jinping Qu¹, Yingjun Wang^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09161

Abstract In the topology optimization problem of mechanical structures, the optimization objectives are mainly focused on the compliance minimization, displacement minimization, stress minimization, and so on. However, in practical engineering, these kinds of optimization objectives do not meet all the requirements. Some structures, such as wind turbine blades and engine blades of aircrafts, are required to maintain a superior aerodynamic shape under external loads. This puts a higher requirement on the local deformation homogenization of the structure. Therefore, we proposed a topology optimization method for the minimization of local relative displacement differences considering stress constraints. First, we present a specific topology… More >

Xiaojun Zhang¹, Jun Li^1,2,*, Wei Lian², Gonghui Liu¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.26, No.1, pp. 1-1, 2023, DOI:10.32604/icces.2023.010343

Abstract In recent years, shale gas development in Fengnan 4 well area of Xinjiang Oilfield is dominated by platform wells. In contrast to conventional fracturing development, the zipper fracturing is primarily used in this block. In this paper, the finite element model of platform well fracturing is established by establishing the mathematical model of multi-cluster fractures interacting with each other, considering the condition of multi-well and multi-fracture. The sequential fracturing of platform wells and the zipper fracturing (well alternating fracturing, fracturing stage alternating fracturing) are simulated in this paper, and the variation law of induced stress and horizontal principal s are… More >

Shuaiqi Fan^1,*, Chenwen Tian², Yunpeng Liu², Ziguang Chen²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09286

Abstract The peridynamic stress-assisted corrosion model is used to study the stability of the corrosion front of metallic materials under tensile mechanical load. The results show that the solution diffusion trends to smooth the corrosion front, while stress corrosion roughens the corrosion front and leads to higher stress concentrations. Compared to the initial concave profile, the initial convex profile helps to reduce the stressassisted corrosion rate and reduces the role of stress in stress-assisted corrosion. The critical stress of stress-assisted corrosion is introduced in the research, below which the roughness of the corrosion front gradually decreases, meaning that the corrosion front… More >

Liuyu Yang¹, Peng Jiang¹, Tiejun Wang^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.3, pp. 1-1, 2023, DOI:10.32604/icces.2023.010538

Abstract Air Plasma Sprayed (APS) Thermal Barrier Coatings (TBCs) have been widely used in land-based gas engines for enhancing the high temperature performance due to their outstanding thermal insulation and high durability. Introducing the segment cracks into APS-TBCs to enhance its durability has been quite attractive approaches nowadays. Qualitative conclusions have been drawn to explore the mechanisms on segment crack formation in the past decades. This article acts as a quantitative study of segment crack formation and crack density regulation mechanism in APS Yttria-Stabilized Zirconia (YSZ) TBCs with experimental observations and analytical calculations. An in-situ stress measurement method is developed through… More >

Xuelian Zhang¹, Junjie Liu^1,*, Jian Li², Zhihong Liang¹, Han Jiang¹, Guozheng Kang¹, Qianhua Kan^1,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.25, No.3, pp. 1-1, 2023, DOI:10.32604/icces.2023.010142

Abstract The last decades have witnessed the real and huge potential applications of hydrogels in various areas, including biomedicine, soft robotics, and flexible electronics. The fatigue of hydrogels challenges their reliability and longevity in service, but the related works are not sufficient. In this work, stress-controlled cyclic fatigue tests of a double-network tough hydrogel, consisting of polyacrylamide and alginate polymer networks, under pure shear deformation are investigated. The effects of peak stress, loading rate, peak stress holding time, and environmental relative humidity on the fatigue of the double-network tough hydrogel are considered. The results show that with the increase in peak… More >