Orlando J. CASTEJÓN

BIOCELL, Vol.37, No.2, pp. 29-36, 2013, DOI:10.32604/biocell.2013.37.029

Abstract The present paper shows by means of confocal laser scanning microscopy the immunoreactivity of rat cerebellar Lugaro cells for calbindin, synapsin-I, PSD-95, GluR1, CaMKII alpha, and N-cadherin. Lugaro cells were easily characterized by their location beneath Purkinje cells. Calbindin revealed immunoreactivity in the cell body, and the axonal and dendritic processes. Synapsin-I labelled the presynaptic endings on Lugaro cells. Synapsin-I and PSD-95 immunoreactivity demonstrated the localization of presynaptic and postsynaptic endings surrounding cell soma, corresponding to afferent extrinsic and intrinsic cerebellar fi bers. GluR1 immunoreactivity of the soma and cell processes indicates that Lugaro cells More >

K.N. Song¹, S. D. Hong¹

Structural Durability & Health Monitoring, Vol.9, No.2, pp. 155-165, 2013, DOI:10.32604/sdhm.2013.009.155

Abstract The IHX (Intermediate Heat Exchanger) of a VHTR (Very High Temperature Reactor) transfers 950° heat generated from the VHTR to a hydrogen production plant. The Korea Atomic Energy Research Institute (KAERI) has manufactured a lab-scale PCHE (Printed Circuit Heat Exchanger) prototype made of SUS316L under consideration as a candidate. In this study, as a part of a hightemperature structural integrity evaluation of the lab-scale PCHE prototype, a macroscopic structural behavior analysis including structural analysis modeling and a thermal/elastic structural analysis was carried out under the test conditions of a helium experimental loop (HELP) as a More >

VIVIANE DAL-SOUTO FRESCURA¹, ANDRIELLE WOUTERS KUHN¹, HAYWOOD DAIL LAUGHINGHOUSE IV², JUÇARA TEREZINHA PARANHOS¹, SOLANGE BOSIO TEDESCO¹

BIOCELL, Vol.37, No.2, pp. 23-28, 2013, DOI:10.32604/biocell.2013.37.023

Abstract Species of the genus Psychotria are used for multiple purposes in Brazilian folk medicine, either as water infusions, baths or poultices. This study was aimed to evaluate the genotoxic and antiproliferative effects of infusions of Psychotria brachypoda and P. birotula on the Allium cepa test. Exposure to distilled water was used as a negative control, while exposure to glyphosate was used as a positive control. The interaction of extracts (as a post-treatment) with the effects of glyphosate was also studied. Results showed that glyphosate and the extracts of both P. brachypoda and P. birotula reduced the mitotic index as compared… More >

MANOOCHEHR MESSRIPOUR¹, AZADEH MESRIPOUR²

BIOCELL, Vol.37, No.2, pp. 17-21, 2013, DOI:10.32604/biocell.2013.37.017

Abstract Tyrosine hydroxylase and tryptophan hydroxylase are key rate limiting enzymes in the biosynthesis of dopamine and serotonin, respectively. Since both enzymes are active in striatum, and affected by age, this study was undertaken to investigate interaction between dopamine and serotonin synthesis in brain striatal synaptosomes of aging rat. Male Wistar rats (3 and 30 month old) were killed by decapitation and brain striatal synaptosomes were prepared by discontinuous Ficoll/sucrose gradient technique. Synaptosomes were incubated in the presence of added pargiline (monoamineoxidase inhibitor), dopamine or serotonin synthesized during 25 min was measured by HPLC, employing electrochemical… More >

LOKMAN VARISLI

BIOCELL, Vol.37, No.1, pp. 11-16, 2013, DOI:10.32604/biocell.2013.37.011

Abstract The cell cycle is a conserved process from yeast to mammals and focuses on mechanisms that regulate the timing and frequency of DNA replication and cell division. The temporal and spatial expression of the genes is tightly regulated to ensure accurate replication and transmission of DNA to daughter cells during the cycle. Although the genes involved in interphase are well studied, most of the genes which are involved in mitotic events still remain unidentified. Since, the discovery of mitosis related genes is still incomplete, we performed a co-expression and gene ontology analysis for revealing… More >

LUCIA PRONSATO, ANABELA LA COLLA, ANA CAROLINA RONDA, LORENA MILANESI, RICARDO BOLAND, ANDREA VASCONSUELO^*

BIOCELL, Vol.37, No.1, pp. 1-9, 2013, DOI:10.32604/biocell.2013.37.001

Abstract Cell lines with high passage numbers exhibit alterations in cell morphology and functions. In the present work, C2C12 skeletal muscle cells with either low (<20) or high (>60) passage numbers (identified as lC2C12 or h-C2C12, respectively) were used to investigate the apoptotic response to H2 O2 as a function of culture age h-C2C12. We found that older cultures (h-C2C12 group) were depleted of mitochondrial DNA (mtDNA). When we analyzed the behavior of Bad, Bax, caspase-3 and mitochondrial transmembrane potential, we observed that cells in the h-C2C12 group were resistant to H2 O2 induction of More >

R. Afshar¹, F. Berto^1,2

Structural Durability & Health Monitoring, Vol.9, No.4, pp. 349-364, 2013, DOI:10.32604/sdhm.2013.009.349

Abstract Using the finite element method, three-dimensional models of a number of periodic blunt and sharp notches subjected to tension loading are carried out. The aim of this research is to investigate the thickness effect on the location of maximum stress and notch stress intensity factor (NSIF) of corresponding blunt and sharp periodic notches respectively. With this aim, a wide range of notch geometries are examined. While for two-dimensional plates weakened by periodic notches some results are available in the literature, this paper first faces with the problem of three-dimensional cases. The total of about 100 More >

A. Likhith Reddy¹, Shirleen Charles¹, C. Bharathi Priya², G.V. Rama Rao², N. Gopalakrishnan^3,4 , A. Rama Mohan Rao³

Structural Durability & Health Monitoring, Vol.9, No.4, pp. 325-347, 2013, DOI:10.32604/sdhm.2013.009.325

Abstract Details of the investigations on an unexplored application of Electro Mechanical Impedance (EMI) technique using smart piezoelectric (PZT) sensors for damage detection of concrete shear wall structures under crack opening and closing is presented in this paper. The behavior and the ability of this method to detect damages, in a heterogeneous quasi-brittle material is studied for its effective utilization in structural health monitoring. The paper discusses the experimental investigations conducted on a concrete shear wall using PZT patches. Conductance data is acquired at different applied lateral displacements of shear wall. Damage index is calculated using More >

V. Mallardo^1,2, M.H. Aliabadi³

Structural Durability & Health Monitoring, Vol.9, No.4, pp. 287-323, 2013, DOI:10.32604/sdhm.2013.009.287

Abstract The optimum location of the sensors is a critical issue of any successful Structural Health Monitoring System. Sensor optimization problems encompass mainly three areas of interest: system identification, damage identification and impact identification. The current paper is intended as a review of the state of the art at the year 2012 and going back to 1990. The above topics have been dealt with in separate contexts so far but they contain interesting common elements to be exploited. More >

Mehdi Mohammadpour Lima^1,2, Dane Miller¹, Jeung-Hwan Doh¹

Structural Durability & Health Monitoring, Vol.9, No.4, pp. 269-285, 2013, DOI:10.32604/sdhm.2013.009.269

Abstract Iran is located in a seismic prone region with several earthquakes occurring annually causing extensive damage to structures and infrastructure. Guilan province is located in the northern part of the country, exhibiting a large population, moderate climate and extensive river system. This region experiences high humidity, several active faults and high seismic hazard potential. This highlights the importance of an active and extensive maintenance and rehabilitation program for the bridges in this region. Structural Health Monitoring (SHM) is an engineering tool used to control changing conditions of infrastructure providing useful information for management, decision making… More >