M.A. Pérez-Limiñana^*, M.M. Sánchez-Navarro, M.J. Escoto-Palacios, F. Arán-Aís, C. Orgilés-Barceló

Journal of Renewable Materials, Vol.4, No.1, pp. 3-8, 2016, DOI:10.7569/JRM.2015.634119

Abstract The tanning i ndustry generates very large quantities of industrial wastes. The advancement of European policy and legislation protecting the environment has prompted the transformation of tannery solid waste materials into valuable co-products, useful to be recycled or employed in other industries. The objective of this work is to obtain gelatine from tannery wastes, in order to reuse it as natural microencapsulating agent in the production of active materials with functional properties. Concretely, this paper focuses on the influence of the extraction temperature on gelatine properties and its microencapsulating ability. An alternative enzymatic pre-treatment to More >

Filomena Barreiro, Ana Vera Machado

Journal of Renewable Materials, Vol.4, No.1, pp. 1-1, 2016, DOI:10.7569/JRM.2016.634101

Abstract a special issue containing 12 papers is presented here.The Guest Editors of this special issue are grateful to Alessandro Gandini, co-editor in-chief of the Journal of Renewable Materials, Linda Mohr, the Journal Editors’ assistant, as well as to the entire journal team for their valuable contributions that made this excellent work possible. Last but not least, our sincere appreciation to the contributing authors for the work performed and to all the reviewers involved, for their critical and con-structive comments on the submitted manuscripts.A special acknowledgement to Martin Scrivener for his constant follow-up and support.We look More >

Mingzhi Luo^1,2, Peili Yu¹, Yang Jin³, Zhili Qian¹, Yue Wang¹, Jingjing Li¹, Peng Shang^2*, Linhong Deng^1*

Molecular & Cellular Biomechanics, Vol.13, No.2, pp. 137-157, 2016, DOI:10.3970/mcb.2016.013.155

Abstract Random positioning machine (RPM) and diamagnetic levitation are two essential ground-based methods used to stimulate the effect of microgravity in space life science research. However, the force fields generated by these two methods are fundamentally different, as RPM generates a dynamic force field acting on the surface in contact with supporting substrate, whereas diamagnetic levitation generates a static force field acting on the whole body volume of the object (e.g. cell). Surprisingly, it is hardly studied whether these two fundamentally different force fields would cause different responses in mammalian cells. Thus we exposed cultured MC3T3-E1… More >

Pranav S. Sapkal^1*, Abhaykumar M. Kuthe¹, Divya Ganapathy², Shantanu C. Mathankar³, Sudhanshu Kuthe⁴

Molecular & Cellular Biomechanics, Vol.13, No.2, pp. 115-136, 2016, DOI:10.3970/mcb.2016.013.131

Abstract Biphasic calcium phosphate scaffolds with 20/80 HA/TCP ratio were fabricated using the 3D-Bioplotting system to heal critical size defects in rabbit tibia bone. Four different architectures were printed in a layer by layer fashion with lay down patterns viz. (a) 0°– 90°, (b) 0°– 45°– 90°– 135°, (c) 0°–108°– 216° and (d) 0°– 60°– 120°. After high-temperature sintering scaffolds were coated with collagen and were further characterized by (FTIR) Fourier Transform Infrared Spectroscopy, (SEM) Scanning Electron Microscopy, (XRD) X-Ray diffraction, Porosity analysis and Mechanical testing. Scaffold samples were tested for its ability to induce cytotoxicity… More >

Mahesh B. Mawale^1,*, Abhaykumar Kuthe², Dr. Padma Pawane³, Sandeep W. Dahake², Jyotilal S²

Molecular & Cellular Biomechanics, Vol.13, No.2, pp. 105-114, 2016, DOI:10.3970/mcb.2016.013.119

Abstract Purpose: The main purpose of this study is to develop a device for the indicative measurement of intraocular pressure (IOP) of eyeball, a key cause for glaucoma. In early diagnosis and treatment of glaucoma accurate measurement of IOP is important. The methods and devices which are available for the measurement of IOP have their own limitations which cause discomfort to the patients during measurement and needs anesthesia. There is a dare need of a device for the measurement of intraocular pressure by making the contact of plunger with closed eyelid eliminating the need of anesthesia… More >

Tushar Kulkarni¹, Dr. Rashmi Uddanwadiker²

Molecular & Cellular Biomechanics, Vol.13, No.2, pp. 87-104, 2016, DOI:10.3970/mcb.2016.013.099

Abstract This paper aims to determine the force required for holding the objects by human hand. A static analysis is performed on mathematical models to obtain holding force considering lower arm as class three lever and by varying the joint angles. Three mathematical models are discussed to quantify the force required to hold any object, for different weight of the object and the joint angles. A noninvasive experimentation using surface electromyogram was performed to determine the forces required by human hand for the same objects used in the mathematical modeling. Twenty-one male subjects participated in this… More >

Arman Nayebosadri¹, Julie Y. Ji^2*

Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 57-85, 2016, DOI:10.3970/mcb.2016.013.069

Abstract The glucocorticoid receptor (GR) has multiple phosphorylation sites that can be activated by MAPKs, which have been previously shown to be activated in response to cyclic stretch in endothelial cells. It is possible therefore that physiological and/or pathological degree of cyclic stretch may also initiate phosphorylation-induced changes in GR subcellular localization as we previously showed with shear stress. However, little is known about the effects of cyclic stretch on glucocorticoid receptor (GR) activity in endothelial cells. We used control and lamin shRNA BAECs and subjected them to ligand (dexamethasone) treatment, physiological stretch (10% at 1… More >

Longling Fan^1,§, Jing Yao^2,§, Chun Yang³, Di Xu², Dalin Tang^1,4*

Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 33-55, 2016, DOI:10.3970/mcb.2016.013.044

Abstract Modeling ventricle active contraction based on in vivo data is extremely challenging because of complex ventricle geometry, dynamic heart motion and active contraction where the reference geometry (zero-stress geometry) changes constantly. A new modeling approach using different diastole and systole zero-load geometries was introduced to handle the changing zero-load geometries for more accurate stress/strain calculations. Echo image data were acquired from 5 patients with infarction (Infarct Group) and 10 without (Non-Infarcted Group). Echo-based computational two-layer left ventricle models using one zero-load geometry (1G) and two zero-load geometries (2G) were constructed. Material parameter values in Mooney-Rivlin… More >

Chunliu He¹, Jiaqiu Wang², Yuxiang Huang¹, Tongjing Zhu¹, Yuehong Miao¹, Zhiyong Li^1,2*

Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 23-36, 2016, DOI:10.3970/mcb.2016.013.027

Abstract Fibrous cap thickness (FCT) is seen as critical to plaque vulnerability. Therefore, the development of automatic algorithms for the quantification of FCT is for estimating cardiovascular risk of patients. Intravascular optical coherence tomography (IVOCT) is currently the only in vivo imaging modality with which FCT, the critical component of plaque vulnerability, can be assessed accurately. This study was aimed to discussion the correlation between the texture features of OCT images and the FCT in lipid-rich atheroma. Methods: Firstly, a full automatic segmentation algorithm based on unsupervised fuzzy c means (FCM) clustering with geometric constrains was… More >

PoojaJhunjhunwala¹, P.M. Padole², S.B. Thombre³

Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 1-21, 2016, DOI:10.3970/mcb.2016.013.001

Abstract This paper presents Computational fluid dynamic (CFD) analysis of blood flow in three different 3-D models of left coronary artery (LCA). A comparative study of flow parameters (pressure distribution, velocity distribution and wall shear stress) in each of the models is done for a non-Newtonian (Carreau) as well as the Newtonian nature of blood viscosity over a complete cardiac cycle. The difference between these two types of behavior of blood is studied for both transient and steady states of flow. Additionally, flow parameters are compared for steady and transient boundary conditions considering blood as non-Newtonian More >