Ishaq Al Salmi¹, Terence Menezes¹, Mohamed EL-Khodary¹, Sandra Monteiro², Ehsan A. Haider¹, Abdullah Alabousi¹

Canadian Journal of Urology, Vol.27, No.3, pp. 10220-10227, 2020

Abstract Introduction: The aim of this study was to evaluate the value of dynamic contrast enhanced (DCE) imaging in multi-parametric prostate MRI (mpMRI) for the detection and staging of prostate cancer in comparison with T2W and DWI images alone in biparametric MRI (bpMRI) in treatment-naïve patients.
Materials and methods: One hundred consecutive patients who underwent a prostate MRI at our institution from June-August 2017, as well as a systematic ultrasound-guided prostate biopsy or prostatectomy, were included. Strictly following PI-RADS v2, the MRI studies were independently interpreted by a body radiologist and a body-imaging fellow on two different occasions… More >

Ronald F. Tutrone¹, William Schiff²

Canadian Journal of Urology, Vol.27, No.3, pp. 10213-10219, 2020

Abstract Introduction: To report the early postoperative patient experience, including symptom response, catheterization, recovery and satisfaction, following treatment with two minimally invasive surgical therapies (MIST) for benign prostatic hyperplasia (BPH): mechanical disobstruction with UroLift prostatic urethral lift (PUL) and tissue ablation with steam injection (Rezum).
Materials and methods: Patient reported outcomes of 53 non-retention patients from two U.S. sites who underwent PUL (n = 30) or Rezum (n = 23) were collected within 2 months post-treatment. There were no exclusion criteria for baseline symptoms, prostate size, or BPH medical therapy. Patients completed questionnaires which assessed postoperative BPH symptoms… More >

Vipin Tyagi¹, Ajay Kumar Sharma², Mahendra Bhandari³

Canadian Journal of Urology, Vol.27, No.3, pp. 10205-10212, 2020

Abstract Introduction: The novel coronavirus disease 2019 (COVID-19) pandemic has afflicted > 3.3 million people around the world since December 2019. Though more than 1000 publications have appeared in scientific journals addressing a plethora of questions, there is a considerable hiatus in understanding the behavior and natural history of the virus and its impact on urology. Also, a modified approach is the need of the hour in taking care of patients, as urologists should safeguard their teams, families, and patients.
Material and methods: The authors have used guidelines from the USA, Canada, UK, Europe, and India for making… More >

Alan J. Wein

Canadian Journal of Urology, Vol.27, No.3, pp. 10201-10204, 2020

Abstract This article has no abstract. More >

Leonard G. Gomella

Canadian Journal of Urology, Vol.27, No.3, pp. 10199-10200, 2020

Abstract This article has no abstract. More >

Jordan L. Allen, Marcus O. Erdman, Joseph Y. Clark

Canadian Journal of Urology, Vol.27, No.4, pp. 10342-10345, 2020

Abstract Xanthogranulomatous pyelonephritis is a rare variant of pyelonephritis that often requires radical surgery. We report a case of a 51-year-old female patient who was managed with prolonged placement of nephrostomy tubes prior to surgery. This case illustrates the importance of surgical optimization of a poor operative candidate and the use of nephrostomy tubes as a temporizing management strategy. More >

Ying Yan Zhong¹, Luke McLean², Andrew Buckle^1,2, Shankar Siva², Ben Tran²

Canadian Journal of Urology, Vol.27, No.4, pp. 10339-10341, 2020

Abstract Pazopanib, a tyrosine kinase inhibitor, has been a standard first-line treatment for metastatic renal cell carcinoma (mRCC). Recent trials combining pazopanib with programmed cell death protein 1 (PD-1) inhibitors, including pembrolizumab, have shown excessive hepatotoxicity. We report a case of fatal hepatotoxicity from vanishing bile duct syndrome (VBDS) associated with pazopanib treatment, in a patient previously exposed to pembrolizumab. This is the first report of pazopanibinduced VBDS. We postulate whether prior exposure to pembrolizumab predisposed towards pazopanib-induction of VBDS, and discuss potential risks of sequential PD-1 inhibitor followed by pazopanib in mRCC, due to prolonged More >

Nathan Cheng, Gina Kirkpatrick, Debra L. Fromer

Canadian Journal of Urology, Vol.27, No.4, pp. 10336-10338, 2020

Abstract Condyloma acuminata are epidermal lesions caused by the human papillomavirus (HPV) most commonly affecting the anogenital region. Urethral involvement is uncommon, and may mimic other urethral lesions. In this case report, a 62-year-old patient presents with what was believed to be a urethral caruncle and underwent successful resection with the final pathologic diagnosis of urethral condyloma. The clinical features and diagnosis are reviewed. This condition should be considered in the differential diagnosis of females with known HPV or those who are deemed higher risk with unprotected sexual encounters. More >

Patrick J. Hensley, Amanda F. Saltzman, Ali M. Ziada

Canadian Journal of Urology, Vol.27, No.4, pp. 10329-10335, 2020

Abstract Introduction: Management of pediatric renal masses has lagged behind adult paradigms adopting minimally invasive surgery (MIS) and nephron-sparing surgery (NSS). This study investigated national practice patterns between pediatric urologists (PU) and pediatric surgeons (PS) in pediatric renal malignancy.
Materials and methods: The Pediatric National Surgical Quality Improvement Program database was queried for CPT codes for radical/partial nephrectomy from 2012-2017 performed for renal malignancy. Patients were grouped by specialty and operative approach.
Results: PU managed 175 (17%) patients while PS managed 811 (77%). PU were more likely to use MIS (14% versus 5%, p < 0.001) and NSS (33%… More >

Dean S. Elterman¹, Karl Coutinho², Judith C. Hagedorn³

Canadian Journal of Urology, Vol.27, No.4, pp. 10322-10328, 2020

Abstract Urethral stricture disease can be difficult to treat and stricture recurrence is common. The management of stricture disease has evolved and urethroplasty can achieve a high rate of lasting urethral patency. Nevertheless, endoscopic treatments still seem to have sub-optimal outcomes with high stricture recurrence rates. The Optilume drug-coated balloon represents a step forward in the endoscopic management of urethral strictures. The drug-coated balloon may offer an intermediate step prior to repeated dilations, urethrostomies, or urethroplasty. This treatment modality is a promising alternative to current endoscopic management and an option for patients that are poor surgical More >