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CASE REPORT
A case of penile melanoma illustrating the low sensitivity of frozen sections in the assessment of sentinel lymph nodes
1
Department of Surgery, Division of Surgical Oncology
2
Department of Pathology, Royal Victoria Hospital,
McGill University Health Centre, Montreal, Quebec, Canada
Address correspondence to Dr. Antoine Loutfi, Royal
Victoria Hospital, 687 Pine Avenue, Room S10.22, Montreal,
Quebec H3A 1A1 Canada
Canadian Journal of Urology 2003, 10(4), 1947-1949.
Download PDFAbstract
A 75 year-old uncircumcised man presented with a 1.1 mm thick malignant melanoma on the ventral aspect of the glans penis. He underwent isosulfan blue and technetium 99m guided sentinel lymph node (SLN) biopsy and distal penectomy with 2 cm margins. This is the third reported case of penile melanoma using both markers for SLN mapping. While frozen sections and H & E stains were negative, S-100 and HMB-45 immunohistochemistry revealed micrometastasis in one of the sentinel nodes. This case illustrates that any discussion with the patient about management and prognosis should await immunohistochemistry results.Keywords
malignant melanoma, penile, sentinel node biopsy, immunohistochemistry, sensitivity
Cite This Article
APA Style
Andonian, S., Meterissian, S.H., Watters, A.K., Loutfi, A. (2003). A case of penile melanoma illustrating the low sensitivity of frozen sections in the assessment of sentinel lymph nodes. Canadian Journal of Urology, 10(4), 1947–1949.
Vancouver Style
Andonian S, Meterissian SH, Watters AK, Loutfi A. A case of penile melanoma illustrating the low sensitivity of frozen sections in the assessment of sentinel lymph nodes. Can J Urology. 2003;10(4):1947–1949.
IEEE Style
S. Andonian, S.H. Meterissian, A.K. Watters, and A. Loutfi, “A case of penile melanoma illustrating the low sensitivity of frozen sections in the assessment of sentinel lymph nodes,” Can. J. Urology, vol. 10, no. 4, pp. 1947–1949, 2003.
Copyright © 2003 The Author(s). Published by Tech Science Press.This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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