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  • Open AccessOpen Access

    EDITORIAL

    What residents need

    Laurence H. Klotz
    Canadian Journal of Urology, Vol.10, No.4, pp. 1914-1914, 2003
    Abstract This article has no abstract. More >

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  • Open AccessOpen Access

    ARTICLE

    Assessing the goals of urology residency training: perceptions of practicing urologists in British Columbia

    Kevin B. Morrison, Neil J. McLean, Andrew E. MacNeily
    Canadian Journal of Urology, Vol.10, No.4, pp. 1917-1923, 2003
    Abstract Purpose: In an effort to evaluate the perceived utility of specific Royal College of Physicians and Surgeons of Canada (RCPSC) urology residency training objectives we conducted a survey of the practicing urologists of British Columbia (BC).
    Materials and methods: A two page semi-structured survey was designed. Validity was evaluated for clarity, content and ease of completion. The survey was mailed-out to all 61 practicing urologists in BC. The survey population was divided into urban, rural, and academic according to location of practice.
    Results: Survey response rate was 79% with varying subgroup rates: urban-69% (20/29), rural-94% (17/18) and academic… More >

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  • Open AccessOpen Access

    ARTICLE

    Alterations of p53 are common in early stage prostate cancer

    Sean R. Downing1,2, Pamela J. Russell1,2, Paul Jackson1,2
    Canadian Journal of Urology, Vol.10, No.4, pp. 1924-1933, 2003
    Abstract Introduction: Mutations in the p53 tumor suppressor gene are generally believed to be a late event in the progression of prostate cancer, and are associated with androgen-independence, increased angiogenesis, metastasis, recurrence, and a worse prognosis. In this review, we examine the current literature available on p53 mutations found in prostate cancer and focus on stages A (T1) and B (T2) of the disease. The alteration of genes involved in p53 regulation are also examined, as well as animal models that support an early role for p53 in the initiation and development of prostate cancer.
    Results: We report… More >

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  • Open AccessOpen Access

    ARTICLE

    Surgery versus collagen for female stress urinary incontinence: economic assessment in Ontario and Quebec

    Mark Oremus1,2, Jean-Paul Collet1,2,3, Stanley H. Shapiro1,2, John Penrod4,5, Jacques Corcos6,7
    Canadian Journal of Urology, Vol.10, No.4, pp. 1934-1944, 2003
    Abstract Introduction and objective: The purpose of this study was to evaluate the cost-effectiveness of surgery versus collagen injection to treat female stress urinary incontinence after the failure of initial surgical treatment. The analysis was conducted from the health care system perspectives of Ontario and Quebec.
    Materials and methods: A decision-tree was constructed to compare each of three surgeries (i.e., retropubic suspension, transvaginal suspension, sling procedures) with collagen. An average cost estimate was generated for each intervention, as was an incremental cost-effectiveness ratio for each surgery-collagen comparison.
    Results: In both Ontario and Quebec, the treatment with the lowest average cost… More >

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    16

  • Open AccessOpen Access

    RESIDENT’S CORNER

    A case of transitional cell carcinoma seeding of small bowel anastomosis after radical cystoprostatectomy

    Stephen A. Lazarou, Munir Jamal, Thomas Short
    Canadian Journal of Urology, Vol.10, No.4, pp. 1945-1946, 2003
    Abstract We present a case in which a man developed transitional cell carcinoma of the small bowel 6 months after having undergone a cystoprostatectomy and ileal conduit urinary diversion. More >

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  • Open AccessOpen Access

    CASE REPORT

    A case of penile melanoma illustrating the low sensitivity of frozen sections in the assessment of sentinel lymph nodes

    Sero Andonian1, Sarkis H. Meterissian1, A. Kevin Watters2, Antoine Loutfi1
    Canadian Journal of Urology, Vol.10, No.4, pp. 1947-1949, 2003
    Abstract A 75 year-old uncircumcised man presented with a 1.1 mm thick malignant melanoma on the ventral aspect of the glans penis. He underwent isosulfan blue and technetium 99m guided sentinel lymph node (SLN) biopsy and distal penectomy with 2 cm margins. This is the third reported case of penile melanoma using both markers for SLN mapping. While frozen sections and H & E stains were negative, S-100 and HMB-45 immunohistochemistry revealed micrometastasis in one of the sentinel nodes. This case illustrates that any discussion with the patient about management and prognosis should await immunohistochemistry results. More >

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  • Open AccessOpen Access

    CASE REPORT

    Primary amyloidosis of the bladder treated with partial cystectomy

    Nejd F. Alsikafi1, R. Corey O’Connor1, Ximing J. Yang2, Gary D. Steinberg1
    Canadian Journal of Urology, Vol.10, No.4, pp. 1950-1951, 2003
    Abstract A 56-year-old man presented with a 1-year history of intermittent gross, painless hematuria. Extensive evaluation revealed primary localized amyloidosis of the urinary bladder. Despite several endoscopic resections and fulgurations, the patient continued to have episodes of significant hematuria due to recurrent amyloid deposition. He was then successfully treated with partial cystectomy. At 60 months following surgery, the patient remains free of recurrent or systemic disease. More >

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