Home / Journals / CJU / Online First
Special Issues
Table of Content
  • Open Access

    CASE REPORT

    Unusual metastatic patterns of urologic malignancies: a case series and literature review

    Kursad Donmez1,*, Enis Mert Yorulmaz2, Enes Candemir2, Serkan Ozcan2, Osman Kose2, Sacit Nuri Gorgel2, Yigit Akin2
    Canadian Journal of Urology, DOI:10.32604/cju.2025.068294
    Abstract Background: Urologic cancers typically metastasize to common organs, while spread to sites such as the heart, hand, cranial bones, penis, or tonsil is exceedingly rare. The clinical relevance and prognostic impact of these unusual metastases remain unclear. This case series highlights six exceptional cases, providing unique insights to support awareness and management. Case Description: We retrospectively analyzed six cases of patients diagnosed with urologic cancers who developed metastases at uncommon sites. Each case was evaluated based on clinical presentation, imaging findings, histopathological confirmation, treatment course, and outcomes. Relevant literature was reviewed to contextualize findings. Among the… More >

  • Open Access

    HOW I DO IT

    Suprapubic transvesical adenoma resection of the prostate (STAR-P): step-by-step technique

    Christian Gozzi1, Bruno Bucca2,*, Orietta Dalpiaz3, Aldo Brassetti4, Luca Matteo Gobbi2, Greta Basile2, Miroslav Djordjevic5,6
    Canadian Journal of Urology, DOI:10.32604/cju.2025.068035
    Abstract Overview: Surgical management of benign prostatic hyperplasia (BPH) has evolved significantly, incorporating various minimally invasive procedures aimed at reducing morbidity and optimizing patient outcomes. Despite advancements, transurethral approaches continue to pose risks such as urethral strictures and urinary incontinence due to mechanical and thermal stress. To address these limitations, the Suprapubic Transvesical Adenoma Resection of the Prostate (STAR-P) was developed, offering a direct suprapubic route that bypasses the urethra entirely. Recent studies have validated STAR-P as both feasible and safe, emphasizing advantages such as enhanced visualization of the urinary sphincter, minimized urethral trauma, effective hemostasis,… More >

  • Open Access

    REVIEW

    Prostate specific membrane antigen (PSMA) as a biomarker in early and localized advanced prostate cancer: a narrative review

    Jonathon Carll1,2,3,*, Jacinta Bonaddio1, Dixon Woon1,4,5, Marlon Perera1,4,5,6, Nathan Lawrentschuk2,3,5,6, Thilakavathi Chengodu1,3
    Canadian Journal of Urology, DOI:10.32604/cju.2025.068908
    Abstract Prostate-specific membrane antigen (PSMA) is a surface membrane antigen that is highly overexpressed in prostate cancer, with heterogenous expression throughout the natural history of the disease. This has generated significant interest as a potential biomarker for use in early diagnosis and treatment of prostate cancer. We reviewed the literature surrounding PSMA and its current clinical applications in diagnosing and managing early prostate cancer that is confined to the prostate and local lymph nodes. A search on PubMed, Medline, and Web of Science was performed using the following keywords: “PSMA”, “Prostate Specific Membrane Antigen”, “Prostate cancer”,… More >

  • Open Access

    ARTICLE

    Endocrine stimulation in men with non-obstructive azoospermia and low serum testosterone prior to micro-TESE: hormonal response as a predictor of sperm retrieval

    Shlomi Barak1, Netanel Waldenberg1, Aharon Peretz2, Reut Bartoov1, Guy Bar1, Snir Dekalo3,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.066936
    Abstract Background: Hormonal treatment and response as a predictor of sperm retrieval prior to microdissection testicular sperm extraction (micro-TESE) are not well established in the current literature. This study aimed to investigate the hormonal response as a predictor of sperm retrieval among men with nonobstructive azoospermia (NOA). Methods: Seventy-seven consecutive patients who had testosterone levels ≤ 14 nmol/L were treated medically with an aromatase inhibitor or recombinant human chorionic gonadotropin (rec-hCG) prior to micro-TESE and were included. Thirty-four (44.2%) had unexplained NOA (UNEX), 25 (32.5%) had Klinefelter syndrome (KS), 8 (10.4%) had a history of cryptorchidism… More >

  • Open Access

    REVIEW

    Progress of the pathogenesis in varicocele: a narrative review

    Liang Dong1,#, Jialu Xin1,#, Jingyi Zhang2, Zheng Liu2, Junjun Li3,*, Xujun Yu1,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.068263
    Abstract Varicocele (VC) is widely recognized as a prevalent and clinically significant cause of male infertility. However, the comprehensive pathogenic mechanisms underlying VC development and progression remain incompletely understood, creating an important knowledge gap in the field of andrology. This review establishes that VC pathogenesis centers on abnormal vascular remodeling and integrates multiple contributing elements, including anatomical abnormalities, biochemical disturbances, genetic factors, low body mass index (BMI), age, and specific sports habits, while secondary varicoceles are primarily induced by compressive pathologies. Through a systematic synthesis of current evidence and recent advances, this review aims to elucidate More >

  • Open Access

    ARTICLE

    Initial case series and perioperative outcomes of single-port robotic radical prostatectomy: the Italian experience

    Gianluca Spena1, Francesco Passaro1, Achille Aveta1, Roberto Contieri1,*, Alessandro Izzo1, Giuseppe Quarto1, Giovanni Grimaldi1, Luigi Castaldo1, Dario Franzese1, Raffaele Muscariello1, Savio Domenico Pandolfo2, Antonio Tufano3, Sisto Perdonà1
    Canadian Journal of Urology, DOI:10.32604/cju.2025.068026
    (This article belongs to the Special Issue: Prostate Cancer: Biomarkers, Diagnosis and Treatment)
    Abstract Background: The Da Vinci Single-Port Robotic System (Da Vinci-SP), introduced by Intuitive (CA, USA) in 2018 in the USA and in 2024 in Europe, integrates advanced features like a flexible camera and articulating instruments. It has garnered significant interest in urology. Our report presents the first described European series of Radical Prostatectomies using the Da Vinci SP at the leading Italian center, Istituto Nazionale Tumori di Napoli, IRCCS “G. Pascale” Foundation, detailing the technical differences and challenges faced by experienced multiport robotic surgeons. Methods: Sixteen patients have been enrolled and underwent Single-Port (SP) Robot-Assisted Radical… More >

  • Open Access

    CASE REPORT

    Robot-assisted partial nephrectomy during simultaneous extracorporeal membrane oxygenation and impella® in a candidate for left ventricular assist device as a bridge for cardiac transplant: a case report

    Francesco Cianflone1, Giuseppe Ottone Cirulli1, Alessio Villano1, Mohammad Eisa Ali1, Mirko Belliato2, Roberto Veronesi2, Germana Bichisao3, Carlo Marchetti1, Simona Secondino4, Paolo Pedrazzoli4,5, Stefano Pelenghi6, Carlo Pellegrini6,7, Andrea Ringressi1, Richard Naspro1,7,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.073002
    Abstract Background: Robot-assisted partial nephrectomy (RAPN) is standard for cT1 renal masses, but its feasibility in patients on temporary mechanical circulatory support is poorly documented. We report RAPN performed while a patient was simultaneously supported with venous-arterial extracorporeal membrane oxygenation (VA ECMO) and Impella®, as part of a staged plan for left ventricular assist device (LVAD) implantation and eventual heart transplantation. Case Presentation: A 51-year-old man presented with ST-elevation myocardial infarction complicated by cardiogenic shock requiring percutaneous coronary intervention with stenting, dual antiplatelet therapy, and combined VA ECMO–Impella® support. During workup for cardiac transplant, computed tomography (CT) staging… More >

  • Open Access

    CASE REPORT

    Penile ring strangulation injury, what to do when the bolt cutters don’t work: a case report

    Nicole Handa*, Matthew T. Hudnall, Channa Amarasekera
    Canadian Journal of Urology, DOI:10.32604/cju.2025.070415
    Abstract Background: Penile constriction rings are most used for sexual pleasure and the management of sexual dysfunction. However, they pose a risk of injury and can be challenging to remove when strangulation occurs. Case Description: We present a case of a patient with urinary retention and a strangulation injury from a penile constriction ring present for 19 h before initial presentation. Multiple attempts to remove the penile ring were unsuccessful, and ultimately, operative management was required. Conclusions: We describe an effective technique for the removal of a stainless-steel penile constriction ring using a Stryker 505 power revision More >

  • Open Access

    ARTICLE

    A nutritional-inflammatory index for early prediction of inpatient urinary tract infection risk after acute stroke in the elderly

    Shanhong Luo1, Hongjuan Xu2,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.069884
    Abstract Background: Early detection and timely treatment of urinary tract infections (UTIs) can prevent the aggravation of the inflammatory response following a stroke and enhance the recovery of neurological function. This study aimed to develop a simple scoring system by integrating nutritional and inflammatory markers to predict the occurrence of UTIs in patients with acute stroke. Methods: Reviews of 1011 patients with acute stroke were retrieved. The Geriatric Nutritional Risk Index (GNRI) and systemic inflammation response index (SIRI) were utilized to develop a composite score of nutritional-systemic inflammation response index (G-SIRI). The primary endpoint was the… More >

  • Open Access

    ARTICLE

    Nonlinear association between estimated glucose disposal rate and kidney stones: a cross-sectional study

    Zhenzhen Yang1,#, Linxin Jiang2,#, Shan Yin3,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.069717
    Abstract Objectives: Kidney stone disease is increasingly prevalent and may be linked to metabolic factors such as insulin resistance, but there is currently no direct evidence connecting estimated glucose disposal rate (eGDR) to kidney stones. This study aimed to investigate the relationship between eGDR and kidney stone prevalence. Methods: We conducted a cross-sectional analysis utilizing data from the National Health and Nutrition Examination Survey (NHANES) from 2007–2018, including 29,753 participants aged 20 years and older. Weighted multivariable logistic regression and nonlinear models were employed to assess the relationship between eGDR and self-reported kidney stone history. Results: Among… More >
    Graphic Abstract

    Nonlinear association between estimated glucose disposal rate and kidney stones: a cross-sectional study

  • Open Access

    CASE REPORT

    Transperineal approach for penetrating injury of corpus spongiosum and bulbous urethra caused by vesicourethral foreign body: a case report

    Kazuki Yanagida1,2, Daisuke Watanabe1,2,3,*, Hazuki Inoue1, Takashi Ujiie1, Akio Mizushima2,3
    Canadian Journal of Urology, DOI:10.32604/cju.2025.068677
    Abstract Background: Vesicourethral foreign bodies are frequently encountered in urological emergency departments; however, cases of penetrating injury to the corpus spongiosum penis and bulbous urethra are rare. Case Description: A 64-year-old man presented with difficulty removing a foreign body that he had inserted into his urethra for masturbation. Abdominal computed tomography (CT) revealed a rod-shaped foreign body lodged from the bulbous urethra to the posterior wall of the bladder. Cystoscopy confirmed penetration of the foreign body into the urethral sponge at the bulbous urethra. An attempt was made to remove the foreign body transurethrally, but it was… More >

  • Open Access

    ARTICLE

    Adverse histological features are more commonly observed in hypergonadotropic prostate cancer patients

    Taras Shatylko1,*, Ruslan Safiullin1, Safar Gamidov1,2, Tatiana Ivanets1, Ramazan Mammaev2, Kanan Guluzade2, Ilia Rodin3, Gennadiy Sukhikh1
    Canadian Journal of Urology, DOI:10.32604/cju.2025.064572
    Abstract Background: Some patients with prostate cancer have elevated gonadotropin levels. It is unknown, however, whether this condition directly influences carcinogenesis in the prostate. It is also unknown whether any specific hormone levels are useful to predict aggressive disease. The potential role of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in prostate physiology is widely discussed. The study aimed to evaluate whether patients with this endocrine pattern have different outcomes following radical prostatectomy. Methods: This was a prospective cohort study of consecutive patients undergoing robot-assisted radical prostatectomy at the Andrology and Urology Department, National Medical Research… More >

  • Open Access

    CASE REPORT

    Clear cell sarcoma of the kidney with inferior vena cava tumor thrombus in a pediatric patient: a case report

    Bo Yin1,#, Xingyu Long2,#, Zhi Wang1, Feng Ning1, Kan Wang2, Jun He1,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.067189
    Abstract Background: Clear cell sarcoma of the kidney (CCSK) is a rare and highly aggressive pediatric renal malignancy with a marked propensity for metastatic spread. Cases of CCSK associated with inferior vena cava (IVC) tumor thrombus (IVCTT) are exceptionally uncommon in the literature. We report a case of CCSK with IVCTT in a 15-month-old male infant. Case Description: We reported a case admitted in May 2020 for a 3-day history of fever and hematuria. Abdominal CT revealed an unevenly enhanced mass and low-density shadows within the IVC. The diagnosis of CCSK was confirmed via needle biopsy. The… More >

  • Open Access

    ARTICLE

    Evolution toward early stent removal and reduced antibiotic prophylaxis post-cystectomy

    Jessica L. Wenzel1, Wesley H. Chou1,*, Eric J. Robinson2, Solange Bassale3, Paul Jones4, Sudhir Isharwal1,3, Christopher L. Amling1,3, Kamran P. Sajadi1, Jen-Jane Liu1,3
    Canadian Journal of Urology, DOI:10.32604/cju.2025.071079
    Abstract This article has no abstract. More >

  • Open Access

    MINI REVIEW

    Patient reported outcome measures: their evolution and expansion in urology

    Ankith P. Maremanda*, Anna Faris, Benjamin N. Breyer
    Canadian Journal of Urology, DOI:10.32604/cju.2025.064433
    Abstract We describe the history of Patient-Reported Outcome Measures (PROMs) in medicine, with a focus on the development and use of the International Index of Erectile Function (IIEF) in urologic practice. PROMs emerged in the 1970s with tools like the Sickness Impact Profile, designed to capture patients’ perspectives on how disease affects daily life. In the 1990s, PROMs entered urology with the creation of the International Prostate Symptom Score (IPSS) and the IIEF, developed in 1992 and 1997, respectively. As organizations such as the National Institutes of Health began prioritizing PROMs for evaluating sexual function, the More >

  • Open Access

    REVIEW

    Green is the new gold: a systematic review of the environmental impact of urological procedures, telehealth, and conferences

    John Hordines1, Shirley Ge2, Dima Raskolnikov1, Alexander C. Small1, Kara L. Watts1,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.065988
    Abstract Background: The healthcare industry contributes nearly 5% of worldwide carbon emissions. In an effort to mitigate this impact, urology practices can take steps to reduce their carbon footprints. We conducted a systematic review which aimed to summarise the current literature on the environmental impact of urologic-related care. Methods: A systematic literature review evaluating the impact of urologic procedures, telehealth and conferences/interviews was conducted on PubMed and Cochrane databases using a Boolean search strategy and the following search terms: urology, planetary health, environmental impact, carbon emissions, carbon footprint, and waste. Full-text articles published in English were… More >

  • Open Access

    CASE REPORT

    Endourological autologous bypass-ureteroplasty for anastomotic atresia in orthotopic neobladder: a novel surgical approach and case report

    Ao Li1,#, Cai Tang2,#, Xin Wei3,*, Feng Liu1,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.070366
    (This article belongs to the Special Issue: Decoding Renal Development: From Molecular Blueprints to Reconstructive Innovations)
    Abstract Background: Ureteroenteric anastomotic stricture is a common complication after ureteral diversion with radical cystectomy, which leads to hydronephrosis, infection, and chronic renal failure. Although ureteroneocystostomy is reliable, its high degree of invasion often causes great damage and postoperative complications in patients. Therefore, we offer a new endoscopic approach with relatively limited invasion for severe obstructions such as ureteroenteric anastomotic atresia. Case Description: A 65-year-old man underwent radical cystectomy and urinary diversion of orthotopic neobladder and standardized chemotherapy for high-risk non-muscle-invasive bladder cancer. Severe left hydronephrosis was then detected due to ureteroenteric anastomotic atresia. Percutaneous nephrostomy was… More >

  • Open Access

    CASE REPORT

    Double blind-ending ureter: diagnostic challenges and robotic-assisted surgical management—case report

    Marco Di Mitri1,2,*, Edoardo Collautti1,2, Cristian Bisanti3, Andrea Zulli1, Alberto Mantovani1, Annalisa Di Carmine3, Michelangelo Baldazzi4, Roberto Lo Piccolo1, Riccardo Coletta1,5, Lorenzo Masieri6, Mario Lima3
    Canadian Journal of Urology, DOI:10.32604/cju.2025.067303
    Abstract Background: Double blind-ending ureter (DBU) is an extremely rare congenital anomaly involving a duplicated ureter with no connection to the renal pelvis or bladder, making diagnosis difficult. Case Description: A 10-year-old girl presented with recurrent abdominal pain and ultrasound evidence of left hydroureteronephrosis. Magnetic resonance imaging (MRI) and three-dimensional (3D) reconstruction revealed a 30 cm blind-ending ureter. Robotic-assisted excision (Da Vinci Xi) was performed safely, preserving adjacent structures. Histology confirmed a nonfunctional ureteral remnant. Conclusions: DBU is a rare duplication variant. Advanced imaging and robotic surgery are essential for accurate diagnosis and effective, minimally invasive treatment. More >

  • Open Access

    ARTICLE

    External validation of the heidenreich criteria for patients with post-chemotherapy residual masses of non-seminomatous germ cell tumor

    Francesco Claps1,2,*, Miguel Ramírez-Backhaus1, Álvaro Gómez-Ferrer1, Juan Manuel Mascarós1, Argimiro Collado Serra1, Augusto Wong1, Ana Calatrava Fons3, Miguel Ángel Climent4, Antonio Amodeo2, Angelo Porreca5, Jose Rubio-Briones1,6
    Canadian Journal of Urology, DOI:10.32604/cju.2025.070162
    Abstract Objectives: Residual Disease after adjuvant chemotherapy for non-seminomatous germ cell tumor (NSGCT) poses a significant clinical challenge and difficulties in tailored management. This study aimed to externally validate the Heidenreich criteria among patients eligible for unilateral post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) for residual masses of NSGCT. Methods: For validation, these criteria were retrospectively applied in 23 patients undergoing PC-RPLND for residual masses of NSGCTs. In patients qualified for unilateral-modified PC-RPLND according to the Heidenreich criteria but treated with fully bilateral dissection, pathological reports were evaluated to identify teratoma or active cancer cells inside the… More >

  • Open Access

    CASE REPORT

    Management of retained bullet fragments from posterior urethra after gunshot wound: a case report

    Sarah M. Kodres–O’Brien*, Mackenzie Koellermeier, Nayan Shah, Peter Langenstroer
    Canadian Journal of Urology, DOI:10.32604/cju.2025.069550
    Abstract Background: Retained bullet fragments in the genitourinary tract following gunshot wound is rare and require removal. Case Description: We present the case of a retained bullet in the prostate following a gunshot wound to the pelvis, which was endoscopically removed. A urethral catheter and suprapubic tube were placed. The patient then had migration of a second bullet fragment into the prostatic urethra six weeks later, requiring open removal. Conclusions: This case shows that several approaches can be considered to remove retained bullet fragments from the urinary tract. Furthermore, access to the bladder via a suprapubic tube More >

  • Open Access

    ARTICLE

    Uretero-enteric strictures after cystectomy: revealing the modifiable risk factors

    Abdelkader Akkad, Franck Bruyere, Ali Bourgi*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.069546
    (This article belongs to the Special Issue: Advances in Diagnosis and Management of Bladder Cancer: From Molecular Insights to Therapeutic Innovations)
    Abstract Objectives: Uretero-enteric strictures are feared complications following cystectomy. Despite surgical advancements, particularly the rise of robot-assisted approaches, the risk factors associated with these strictures remain poorly defined. This study aimed to identify the risk factors associated with uretero-enteric anastomotic strictures after cystectomy, according to the surgical approach and type of urinary diversion (extracorporeal vs. intracorporeal). Methods: We conducted a single-center retrospective study including 340 patients who underwent cystectomy between 2016 and 2024 at Tours University Hospital. Clinical, biological, perioperative, and postoperative data were analyzed. The occurrence of a uretero-ileal anastomotic stricture was defined radiologically by… More >

  • Open Access

    CASE REPORT

    Penile shaft reconstruction after cream self-injection: a case report

    Léa Bollen1,*, Stéphane Rysselinck2, Jean-Philippe Salmin3, Gilles Dosin4
    Canadian Journal of Urology, DOI:10.32604/cju.2025.067192
    Abstract Background: Penile augmentation through injectable substances is becoming increasingly common. A growing number of aesthetic clinics are developing penile enlargement procedures using various injectable materials. Although these procedures are now performed in more controlled and medically supervised environments, their long-term outcomes remain poorly understood. The promotion of such medical treatments contributes to an increasing interest among adult males in self-injection as a method to alleviate psychological distress associated with penile size concerns. At the same time, access to injectable substances through unofficial or unregulated sources has become increasingly easy. Tor our knowledge, we report the… More >

  • Open Access

    CASE REPORT

    Case report: minimally invasive management of two major complications of colonic perforation and pseudoaneurysm formation following nephrostomy tube placement

    Marie-Lou Letouche1,2,*, Aideen Madden2,3, Mariela Corralles2,3, Steeve Doizi2,3, Olivier Traxer2,3
    Canadian Journal of Urology, DOI:10.32604/cju.2025.067253
    Abstract Background: We present a case of two major complications following insertion of a nephrostomy managed in a minimally invasive way. Our case is the first in the literature to describe this minimally invasive treatment technique for colon perforation in a completely asymptomatic patient. Case Description: A 75-year-old female patient with a history of bilateral obstructive uropathy secondary to bilateral radiation-induced ureteric strictures attended for bilateral nephrostomy placement. The patient had a history of endometrial cancer, treated previously by total hysterectomy and bilateral salpingo-oophorectomy with adjuvant chemo-radiotherapy and brachytherapy. Her recovery had been further complicated by the… More >

  • Open Access

    ARTICLE

    Donor-gifted nephrolithiasis: case-based analysis and comparative study

    Maxwell Sandberg1,*, Mark Xu1, Randall Bissette1, Jacob Malakismail2, Niara East3, Robenson Nguyen4, Jackson Nowatzke1, Robert Stratta5, Dean Assimos1,6, Colin Kleinguetl1
    Canadian Journal of Urology, DOI:10.32604/cju.2025.069091
    Abstract Objectives: Donor-gifted nephrolithiasis—the presence of a stone in a donor kidney at the time of transplantation—is rare. Research is limited, and no consensus high-quality evidence guidelines exist, leaving selection criteria and management to individual provider discretion. We aimed to estimate the frequency and analyze patient and graft outcomes of deceased donor (DD) transplant recipients with stones in their kidneys at Wake Forest Baptist Medical Center. Methods: All DD renal transplants or patients receiving most of their care postoperatively after DD renal transplantation at our institution from 1979 to 2025 were reviewed. Stones were considered donor-gifted… More >

  • Open Access

    ARTICLE

    Treatment patterns for genitourinary syndrome of menopause: a TriNetX analysis

    Anushka Ghosh, Maria J. D’Amico, Yash B. Shah, Whitney R. Smith, Mihir S. Shah, Costas D. Lallas, Alana M. Murphy*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.067575
    Abstract Background: Genitourinary syndrome of menopause (GSM) is a highly prevalent, underdiagnosed condition that can significantly impair quality of life (QoL). This study evaluates real-world treatment trends for GSM to better understand current management practices and highlight ongoing gaps in care. The background is in a different font than the rest of the abstract. Methods: We queried the TriNetX database for patients with a diagnosis of postmenopausal atrophic vaginitis (ICD N95.2) and treatment information from 2004–2024. A combination of RxNorm and International Classification of Diseases-10 (ICD) codes was used to classify disease and treatment type, including… More >

  • Open Access

    CASE REPORT

    Pseudoaneurysm after prostate biopsy: case report

    William Daly*, Daniel Pelzman, P. Dafe Ogagan, Stephen V. Jackman
    Canadian Journal of Urology, DOI:10.32604/cju.2025.063778
    Abstract Background: Minor bleeding after prostate biopsy is a relatively common complication, but clinically significant hemorrhage happens rarely. Management of prostatic artery pseudoaneurysm has not been described in the literature. Case Description: In this case, an 84-year-old man presented after prostate biopsy with rectal bleeding and required a massive transfusion. Ultimately, he was found to have a prostatic artery pseudoaneurysm, which to our knowledge is heretofore undescribed after prostate biopsy. Bleeding ultimately stopped spontaneously as the patient deferred angioembolization. He had not recurrent bleeding on follow up but is still deciding on treatment course for newly diagnosed More >

  • Open Access

    ARTICLE

    Unbuckling: an answer to address cuff-related challenges in urethral instrumentation with an artificial urinary sphincter

    Hasan Jhaveri*, Mariela Martinez-Rivera, Brent Nose, Jordan Foreman, Aaron C. Lentz
    Canadian Journal of Urology, DOI:10.32604/cju.2025.068095
    Abstract Objectives: There is limited in vivo data on the maximum safe instrument size that can be passed through an artificial urinary sphincter (AUS) cuff. While 21 French instruments are generally safe with the commonly used 4.5 cm cuff, larger instruments or smaller cuffs may require unbuckling to avoid urethral erosion. This study aimed to identify if artificial urinary sphincter cuff ‘unbuckling’ affects device longevity and risk of erosion. Methods: A retrospective study of patients at a quaternary health system who underwent unbuckling was conducted. Using the Epic Clarity database and Duke Enterprise Data Unified Content Explorer… More >

  • Open Access

    ARTICLE

    Modern diagnostics: ultrasound elastography and magnetic resonance imaging in initial evaluation of testicular cancer

    Şeref Barbaros Arik1,2,*, İnanç Güvenç1,2
    Canadian Journal of Urology, DOI:10.32604/cju.2025.068094
    Abstract Objectives: Differentiating benign from malignant testicular lesions is essential to avoid unnecessary surgery and ensure timely intervention. While conventional ultrasound remains the first-line imaging method, elastography and MRI provide additional functional and structural information. This study assesses the diagnostic utility of testicular elastography and magnetic resonance imaging (MRI) in differentiating benign and malignant testicular lesions. Methods: Patients with sonographically detected testicular masses were retrospectively evaluated using elastography, scrotal MRI, and tumor markers. Quantitative and qualitative imaging findings, lesion size, and laboratory values were recorded. Statistical analyses included Fisher’s exact test, logistic regression, Receiver operating characteristic… More >

  • Open Access

    Gastrointestinal resection is associated with urolithiasis severity among inflammatory bowel disease patients

    Vinay Durbhakula1,*, Ziv Savin1, Einat Savin-Shalom2, Stephanie L. Gold2, Kavita Gupta1, Eve Frangopoulos1, Blair Gallante1, William M. Atallah1, Mantu Gupta1
    Canadian Journal of Urology, DOI:10.32604/cju.2025.067614
    Abstract Background: A well-established correlation exists between Inflammatory Bowel Disease (IBD) and urolithiasis. However, the influence of surgical history on the severity of urolithiasis in IBD patients remains underexplored. This study aims to investigate the association between gastrointestinal (GI) bowel resection and urolithiasis severity in patients with IBD. Methods: This retrospective cohort study analyzed 42 patients diagnosed with both IBD and urolithiasis between 2016 and 2024. Patients were categorized based on their history of bowel resection. Primary outcomes included maximal stone burden, need for urolithiasis surgery, and stone recurrence. Secondary outcomes were stone-related clinical events, multiple… More >

  • Open Access

    CASE REPORT

    Feasibility of water vapor thermal therapy for treating lower urinary tract symptoms in men with localized prostate cancer on active surveillance: a case series

    Mustufa Babar1,*, Farooz Babar2, Noah Hawks-Ladds3, Justin Loloi4, Michael Ciatto5
    Canadian Journal of Urology, DOI:10.32604/cju.2025.066654
    Abstract Background: Prostate cancer is a common malignancy, with many men on active surveillance for localized, low-risk disease also experiencing lower urinary tract symptoms (LUTS) from benign prostatic hyperplasia (BPH). Water Vapor Thermal Therapy (WVTT) is a minimally invasive BPH treatment, but its safety and efficacy in this setting are unclear. Case Description: We report three men with localized PCa on active surveillance who underwent WVTT for LUTS. Conclusions: WVTT appears safe and potentially effective in treating LUTS, especially in those with lower-risk disease and smaller prostate volumes. Further research is needed to confirm safety, efficacy, and More >

  • Open Access

    HOW I DO IT

    Stenting severely obstructed ureters: a useful method for a common challenge

    Yoav Avidor#,*, Ghalib Lidawi#, Muhammad Majdoub, Mohsin Asali, Ronen Rub
    Canadian Journal of Urology, DOI:10.32604/cju.2025.064383
    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Low utilization of intracavernosal injection and penile Doppler ultrasound in the evaluation of erectile dysfunction and Peyronie’s disease

    Joon Yau Leong1, Tyler Gaines2, Zachary J. Prebay1, David Ebbott1, Paul H. Chung1,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.064125
    Abstract Introduction: Despite the diagnostic value of intracavernosal injections (ICI) and penile Doppler ultrasound (PDUS), there remain barriers to widespread clinical adaptation of these methods. The study aimed to evaluate the practice patterns of utilization of ICI and PDUS in the assessment of erectile dysfunction (ED) and Peyronie’s disease (PD). Methods: Using the TriNetX database (Cambridge, MA, USA), adult (≥18 years) male patients with a diagnosis of ED on oral phosphodiesterase-5 (PDE5) inhibitors were identified. Current Procedural Terminology codes were utilized to identify patients who underwent further evaluation with ICI or PDUS, as well as penile… More >

  • Open Access

    ARTICLE

    Current and perceived optimal use of point-of-care ultrasound in urology

    Charles H. Schlaepfer1, Zubin Shetty1, Vignesh T. Packiam1, Chad R. Tracy1, Elizabeth B. Takacs1, Ruslan Korets2, Ryan L. Steinberg1,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.064818
    Abstract Introduction: Point-of-care ultrasound (POCUS) is a valuable tool for clinicians, but little data exists regarding the perceptions of ideal POCUS utilization, as compared to actual use, amongst urologists. We aim to assess how perceptions align or diverge with actual practice. Methods: An institutional review board (IRB)-approved survey was developed and disseminated by email to 6 of 8 American Urologic Association Sections, program directors via the Society of Academic Urologists, and to 2 residency programs. The primary outcome was to assess differences in current and perceived optimal use. Data was collected via the University of Iowa… More >

  • Open Access

    ARTICLE

    Implementation of opioid-reduced protocols after penile prosthesis surgery

    Luke Patrick O’Connor1, Alexander Jordan Henry2, Wendy Michelle Novicoff3, Marwan Ali2, Adam Seth Baumgarten4, Nicolas Martin Ortiz2,*
    Canadian Journal of Urology, DOI:10.32604/cju.2025.065217
    Abstract Background: Postoperative pain management after penile prosthesis (PP) has traditionally required opioid medication. Recently, urologic prosthetic surgeons have sought to establish opioid-free protocols (OFP) and/or opioid-reduced protocols (ORP) for PP postoperative pain management. We sought to investigate the adoption patterns of OFP/ORP among surgeons who perform PP surgery and identify barriers to implementation. Methods: A 13-question confidential survey was sent to members of the Sexual Medicine Society of North America (SMSNA) and the Society of Urologic Prosthetic Surgeons (SUPS) via email. The survey was administered via Qualtrics. A t-test was used to analyze survey responses. Results:More >

  • Open Access

    CASE REPORT

    Brunn’s cyst causing lower urinary tract symptoms in a young adult: A case report with brief review of literature

    Harshdeep Singh*, Pawan Vasudeva, Thiyagarajan Kalaiselvi Aravind
    Canadian Journal of Urology, DOI:10.32604/cju.2025.064435
    Abstract Background: Brunn’s cyst is a seldom encountered etiology in a wide spectrum of causative pathologies producing lower urinary tract symptoms (LUTS) in a young male, causing voiding symptoms, with prompt symptom resolution following surgical management. A diagnostic dilemma may arise, as other bladder neck cystic lesions differ in anatomical location, etiology, and the nature of associated LUTS. Case Description: We report a middle-aged male patient with Brunn’s cyst with a brief description of our management strategies and a review of available literature. Conclusions: Brunn’s cyst is a rare but treatable cause of bladder outlet obstruction in More >

  • Open Access

    ARTICLE

    Performance of fluorescence in situ hybridization in detecting lower versus upper tract urothelial carcinoma

    Song Xu1,2,3,4,5,*, Mengxin Lu1,2,3,4,5, Zhonghua Yang1,2,3,4,5, Hang Zheng1,2,3,4,5
    Canadian Journal of Urology, DOI:10.32604/cju.2025.063069
    Abstract Background: Many studies have evaluated the performance of fluorescence in situ hybridization (FISH) in detecting urothelial carcinoma, while few of them compared it in detecting bladder cancer (BC) vs. upper tract urothelial carcinoma (UTUC). This study aimed to determine and compare the FISH performance in detecting BC and UTUC. Methods: Data of patients with suspected urothelial carcinoma (UC) who accepted FISH from January 2021 to April 2023 were retrieved. The sensitivity and specificity of FISH in detecting BC and UTUC were determined and compared. Results: A total of 145 BC, 62 UTUC, and 170 non-UC patients were… More >

  • Open Access

    CASE REPORT

    Understanding self-inflicted penile strangulation: a case series analysis of clinical management and psychological considerations

    Siddharta Saxena, Vikas Kumar Panwar*, Ankur Mittal, Mohammed Taher Mujahid, Mehul Agarwal, Nalin Kumar Srivastav
    Canadian Journal of Urology, DOI:10.32604/cju.2025.063597
    Abstract Background: Injuries to the penis resulting from self-inflicted strangulation with various objects are uncommon, yet these injuries are more frequently observed in young adults. Medical literature has identified items such as hair, thread, rubber bands, metallic rings, and vacuum erection devices as tools used for this purpose. These constrictive items impede venous return from the penis, potentially leading to severe complications such as ischemia or necrosis. This case series aims to analyse the clinical presentation, management strategies, and psychological dimensions of self-inflicted penile strangulation through a case series.
    Case Presentation: We conducted a retrospective analysis of three… More >

  • Open Access

    CASE REPORT

    Successful treatment of rare vaso-vesical fistula with minimally invasive measures despite prior history of radiotherapy: a case report

    Jordan L. Mendelson1,*, Jordan Kassab1, Phillip Westbrook1, Katie Yang2, Anthony Corcoran,1
    Canadian Journal of Urology, DOI:10.32604/cju.2025.063770
    Abstract Stereotactic body radiotherapy (SBRT) for prostate cancer is a generally well-tolerated treatment but can rarely lead to complications such as fistula formation. We report a 69-year-old male on maintenance ibrutinib for chronic lymphocytic leukemia who developed a fistula between his bladder and vas deferens in the setting of ascending scrotal infection. Despite his prior history of SBRT, the fistula was successfully treated with minimally invasive measures. A combination of abscess debridement, urinary diversion, and broad-spectrum antibiotics helped to achieve fistula resolution. The unique presentation described herein highlights the importance of early aggressive intervention for source More >