Influence of statin use on clinicopathological characteristics of localized prostate cancer and outcomes obtained after radical prostatectomy: a single center study
Susanna Cattarino1, Thomas Seisen1,2, Sarah J. Drouin1,
Raphaële Renard-Penna1, Priscilla Leon1,2, Eva Comperat3,
Pierre Mozer1, Olivier Cussenot1,2, Morgan Rouprêt1,2
Canadian Journal of Urology, Vol.22, No.2, pp. 7703-7708, 2015
Abstract Introduction: To assess the impact of statin use on biochemical recurrence (BCR) of prostate cancer after radical prostatectomy (RP).
Materials and methods: Data from all men treated with robot-assisted laparoscopic RP (RALRP) for localized prostate cancer between 2009 and 2014 at our institution were prospectively collected: age, body mass index (BMI), statin-use status, preoperative prostate-specific antigen (PSA) level, clinical T stage, biopsy Gleason score (bGS), D'Amico risk group, pathological T stage, specimen Gleason score (sGS), multifocality, perineural invasion, positive surgical margins and time to BCR. Univariate and multivariate analysis were performed to test associations between statin… More >