Outcomes of upper tract urothelial cancer managed non-surgically
Jamil S. Syed1, Kevin A. Nguyen1, Alfie Suarez-Sariemento1, Cynthia Leung1, Marianne Casilla-Lennon1, Jay D. Raman2, Brian Shuch1,3
Canadian Journal of Urology, Vol.26, No.2, pp. 9699-9707, 2019
Abstract Introduction: Approximately 7% of patients with localized upper tract urothelial cancer (UTUC) are treated without definitive therapy. Understanding outcomes and alternative therapy would aid in counseling older patients with comorbidities.
Materials and methods: We utilized the National Cancer Database to identify patients with localized UTUC managed non-surgically between 2004 and 2013. Patient demographics, comorbidity, tumor grade, and chemotherapy and radiation utilization were recorded. Survival analyses were performed with the Kaplan-Meier method and a Cox proportional hazard regression model.
Results: We identified 3157 (10.9%) patients with localized UTUC who did not receive definitive surgery. Median age was 79 years,… More >