Home / Journals / CJU / Vol.27, No.1, 2020
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    EDITORIAL

    Boosting Free Testosterone With OTC Natural Supplements: Be Careful What You Wish For

    Leonard G. Gomella
    Canadian Journal of Urology, Vol.27, No.1, pp. 10067-10067, 2020
    Abstract This article has no abstract. More >

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    LEGENDS IN UROLOGY

    LEGENDS IN UROLOGY

    Richard E. Hautmann
    Canadian Journal of Urology, Vol.27, No.1, pp. 10068-10071, 2020
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    ARTICLE

    Three-year outcomes after Aquablation therapy compared to TURP: results from a blinded randomized trial

    Peter Gilling1, Neil Barber2, Mohamed Bidair3, Paul Anderson4, Mark Sutton5, Tev Aho6, Eugene Kramolowsky7, Andrew Thomas8, Barrett Cowan9, Ronald P. Kaufman, Jr.10, Andrew Trainer11, Andrew Arther11, Gopal Badlani12, Mark Plante13, Mihir Desai14, Leo Doumanian14, Alexis E. Te15, Mark DeGuenther16, Claus Roehrborn17
    Canadian Journal of Urology, Vol.27, No.1, pp. 10072-10079, 2020
    Abstract Introduction: To compare 3-year efficacy and safety after prostate resection with Aquablation therapy or transurethral resection of the prostate (TURP) for the treatment of lower urinary tract symptoms related to benign prostate hyperplasia (BPH).
    Materials and methods: One hundred and eighty-one patients assigned to either Aquablation therapy or TURP were followed for 3 years postoperatively. Patients and follow-up assessors were blinded to treatment. Assessments included International Prostate Symptom Score (IPSS), Male Sexual Health Questionnaire (MSHQ-EjD), International Index of Erectile Function (IIEF) and uroflow.
    Results: Over 3 years of treatment, improvements in IPSS scores were statistically similar across groups.… More >

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    ARTICLE

    Assessment of high-grade prostate cancer risk using prostate cancer biomarkers

    Whitney N. Stanton1, E. David Crawford2, Paul B. Arangua3, Francisco G. La Rosa1, Adrie van Bokhoven1, M. Scott Lucia1, Wendy L. Poage4, Alan Partin5, Paul Maroni3, Priya N. Werahera1
    Canadian Journal of Urology, Vol.27, No.1, pp. 10080-10085, 2020
    Abstract Introduction: To identify patients at risk of high-grade prostate cancer using prostate cancer biomarkers.
    Materials and methods: A total of 601 men were screened for prostate cancer in 2012, 2015, and 2016 using prostate cancer biomarkers: prostate health index (phi), 4KScore, and SelectMDx. The first two are blood tests that incorporate several PSA isoforms; SelectMDx measures mRNA levels of homeobox C6 and distal-less homeobox 1 in post-digital rectal examination urine samples. The performance of each biomarker was evaluated using cut-off values based on published literature. Gleason Grade Group (GG) ≥ 2 is considered as high-grade prostate cancer.
    Results:More >

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    COMMENTARY

    Secondary screening tests for prostate cancer: is more information better? Which test is best?

    Judd W. Moul
    Canadian Journal of Urology, Vol.27, No.1, pp. 10086-10086, 2020
    Abstract This article has no abstract. More >

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    ARTICLE

    Implementing a patient safety culture survey to identify and target process improvements in academic ambulatory urology practices: a multi-institutional collaborative

    Alexander J. Skokan1, Ryan W. Dobbs1, Andrew M. Harris2, Christopher D. Tessier3, Kamran P. Sajadi3, Ruchika Talwar1, Ian Berger1, Thomas J. Guzzo1, Justin B. Ziemba1
    Canadian Journal of Urology, Vol.27, No.1, pp. 10087-10092, 2020
    Abstract Introduction: A shared professional culture focused on patient safety is critical to delivering high-quality care. There is a need for objective metrics to help identify target areas for improvement in patient safety culture. The Medical Office Survey on Patient Safety Culture (SOPS) was developed and validated by the United States Agency for Healthcare Research and Quality to measure patient safety culture in the ambulatory setting. In this study we report on safety culture and practices in six academic urology clinics utilizing this validated questionnaire.
    Materials and methods: The SOPS was administered to all staff in ambulatory urology… More >

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    ARTICLE

    Continent cutaneous ileocecal cystoplasty in the treatment of refractory bladder neck contracture and urinary incontinence after prostate cancer treatment

    Jim K. Shen, Kevin G. Chan, Jonathan N. Warner
    Canadian Journal of Urology, Vol.27, No.1, pp. 10093-10098, 2020
    Abstract Introduction: To assess the use, complications, and outcomes of continent cutaneous ileocecal cystoplasty (CCIC) for the management of refractory bladder neck contractures and/or urinary incontinence after prostate cancer therapy.
    Materials and methods: An institutional review board approved database was reviewed for patients who underwent CCIC from January 1, 2003 to December 31, 2018. Preoperative, perioperative and postoperative factors were assessed, including complications and outcomes.
    Results: Thirteen patients were identified. Indications for CCIC included refractory bladder neck contracture (n = 3), urinary incontinence (n = 5), or both (n = 5). Median age was 69. Median follow-up was 78.1… More >

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    ARTICLE

    Hospital-specific antibiograms and antibiotic prophylaxis for prostate biopsies: a reexamination of AUA recommendations

    Mark Mann1, Brian P. Calio1, James Ryan Mark1, Raju Chelluri2, Erich Hufnagel3, Adam Reese4, Costas D. Lallas1, Edouard J. Trabulsi1, Thenappan Chandrasekar1, Patrick J. Shenot1, Ethan Halpern5, Leonard G. Gomella1
    Canadian Journal of Urology, Vol.27, No.1, pp. 10099-10104, 2020
    Abstract Introduction: To assess whether standard American Urological Association (AUA) and other recommendations for prostate biopsy prophylaxis provide sufficient coverage of common urinary organisms responsible for post biopsy infections by comparing local antibiograms in Philadelphia-area hospitals.
    Materials and methods: De-identified culture results derived from antibiograms were collected from six academic and community hospitals in the Philadelphia region. Analysis specifically focused on four major bacterial causes of urinary tract infection following prostate biopsy (Escherichia coli (E. coli), Klebsiella pneumoniae, Proteus mirabilis and Enterococcus faecalis) along with commonly recommended antibiotics including fluoroquinolones (FQ’s), trimethoprim/sulfamethoxazole, ceftriaxone, and gentamicin.
    Results: Bacterial sensitivities to… More >

  • Open AccessOpen Access

    COMMENTARY

    Considerations and alternative approaches to antibiotic prophylaxis for prostate biopsy

    Eric H. Kim, Gerald L. Andriole
    Canadian Journal of Urology, Vol.27, No.1, pp. 10105-10105, 2020
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    ARTICLE

    Mirabegron improves sleep measures, nocturia, and lower urinary tract symptoms in those with urinary symptoms associated with disordered sleep

    Robert A. Petrossian1, Danuta Dynda1, Kristin Delfino1, Ahmed El-Zawahry3, Kevin T. McVary2
    Canadian Journal of Urology, Vol.27, No.1, pp. 10106-10117, 2020
    Abstract Introduction: The role of organized sleep in overall health and quality-of-life (QoL) is critical. Nocturia necessarily disrupts the normal sleep cycle and negatively impacts one’s health, work productivity, and QoL. We investigated, for the first time in an exploratory pilot, the effectiveness of mirabegron for improving sleep disturbance and nocturia.
    Materials and methods: This was a prospective, open-label 12-week trial evaluating the efficacy of mirabegron in 34 men and women with disordered sleep and lower urinary tract symptoms (LUTS). Subjects received mirabegron 25 mg daily for 4 weeks, then increased to 50 mg. Subjects completed the Patient-Reported… More >

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    ARTICLE

    Urinary leak following partial nephrectomy: a contemporary review of 975 cases

    Charles C. Peyton1, Ali Hajiran1, Kevin Morgan2, Mounsif Azizi1, Dominic Tang1, Juan Chipollini1, Scott M. Gilbert1, Michael Poch1, Wade J. Sexton1, Philippe E. Spiess1
    Canadian Journal of Urology, Vol.27, No.1, pp. 10118-10124, 2020
    Abstract Introduction: To describe the incidence, contemporary management, risk factors and outcomes of urinary leak following open and robotic partial nephrectomy at a tertiary care, comprehensive cancer center.
    Materials and methods: We reviewed 975 patients who underwent partial nephrectomy at Moffitt Cancer Center from January 2009 to May 2017. Patient demographic, perioperative and follow-up data were recorded and compared, stratified for postoperative urine leak. Fisher’s exact and Wilcoxon sum-rank testing were performed for categorical and continuous variables as indicated.
    Results: Twenty-three of 975 (2.3%) patients experienced a urine leak after partial nephrectomy. Median nephrometry score for urine leak patients… More >

  • Open AccessOpen Access

    ARTICLE

    Injection location does not impact botulinum toxin Aeffcacy in interstitial cystitis/bladder pain syndrome patients

    Robert J. Evans1, Tyler Overholt1, Marc Colaco1, Stephen J. Walker1,2
    Canadian Journal of Urology, Vol.27, No.1, pp. 10125-10129, 2020
    Abstract Introduction: Botulinum toxin A (BTX-A) is currently used as a fourth-line therapeutic option for interstitial cystitis/bladder pain syndrome (IC/BPS) management. The purpose of this study was to determine if BTX-A injection can mitigate pain and if injection location (i.e., trigone-including versus trigone-sparing injection template) impacts treatment efficacy and/or treatment complications profile.
    Materials and methods: Female IC/BPS patients refractory to conservative management strategies were prospectively enrolled and asked to complete a baseline history and physical exam, post-void residual (PVR) urine volume determination, O’Leary Sant (OLS) questionnaire, and Pelvic Pain and Urgency/Frequency Symptom Scale (PUF) questionnaire. Participants were randomly… More >

  • Open AccessOpen Access

    ARTICLE

    Safety of retrograde pyelography for infected ureteral stones

    Joshua Palka, Zaid Farooq, Barrett G. Anderson
    Canadian Journal of Urology, Vol.27, No.1, pp. 10130-10134, 2020
    Abstract Introduction: Initial management of obstructing ureteral stones with concomitant urinary tract infection (UTI) includes prompt renal decompression and antibiotics. Some urologists theorize that performing retrograde pyelography (RGP) at the time of ureteral stent placement may cause pyelovenous backflow of bacteria thereby worsening clinical outcomes. We compared outcomes in patients with infected ureteral stones who underwent RGP versus no RGP prior to stent placement.
    Materials and methods: A retrospective chart review was conducted involving patients who presented between 2015 and 2017 with an obstructing ureteral stone and associated UTI. Computed tomography scans were evaluated for stone size and… More >

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    RESIDENT’S CORNER

    Testicular torsion in brothers

    Alexandra L. Tabakin, Nicholas J. Farber, Joseph Barone
    Canadian Journal of Urology, Vol.27, No.1, pp. 10135-10137, 2020
    Abstract Testicular torsion is a common pediatric emergency. Predisposing factors and other risk factors for testicular torsion have not been fully elucidated. This case report highlights teenage brothers who each experienced rightsided testicular torsion at nearly the same age, just 1 year apart. Because of their parents’ urgency in seeking medical attention, the affected testicles in both patients were salvaged. We also review the current literature in regards to etiology, inheritance, and patient and parental education. More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Life-threatening gross hematuria: case report of renal artery aneurysm

    Kelly R. Pekala1, Oluwaseun Orikogbo2, Liam C. Macleod1, Louis D’Agostino1
    Canadian Journal of Urology, Vol.27, No.1, pp. 10138-10141, 2020
    Abstract Renal artery aneurysms can present with gross hematuria and are potentially life-threatening in cases of rupture. We report a case of a young male with no prior genitourinary history who presents to an emergency department with sudden onset gross hematuria, clot retention, and right-sided flank pain. On evaluation, he was found to have a renal artery aneurysm bleeding into his collecting system and underwent renal artery embolization and rapid resolution of his hematuria. Renal vascular pathology should be considered in the differential diagnosis and timely diagnosis of this condition is imperative as surgical interventions have More >

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