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EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.16, No.1, pp. 4445-4446, 2009
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LEGENDS IN UROLOGY

Mark S. Soloway
Canadian Journal of Urology, Vol.16, No.1, pp. 4447-4449, 2009
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IN MEMORIAM

Jack Sales, Datta Wagle
Canadian Journal of Urology, Vol.16, No.1, pp. 4450-4451, 2009
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ARTICLE

Ofer N. Gofrit, Marcelo A. Orvieto, Kevin C. Zorn, Gary D. Steinberg, Gregory P. Zagaja, Arieh L. Shalhav
Canadian Journal of Urology, Vol.16, No.1, pp. 4452-4457, 2009
Abstract Background and purpose: Single renal unit models are invaluable for studies in renal physiology, transplantation and response to ischemic injury. Glomerular filtration rate (GFR) is commonly used for evaluation of renal function. Measuring the GFR involves relatively complicated and expensive systems. In this study we determined whether serum creatinine (Scr) can predict the GFR in this model.
Materials and methods: Right laparoscopic nephrectomy was performed in 46 female pigs weighing 25 kg-30 kg. Twelve days later the left kidney was exposed to various periods of warm ischemia (30, 60, 90, and 120 minutes). Scr and GFR (using the… More >

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EDITORIAL COMMENT

James Listman
Canadian Journal of Urology, Vol.16, No.1, pp. 4457-4457, 2009
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ARTICLE

Alvaro Morales, Angela Black, Janet Clark-Pereira, Laurel Emerson
Canadian Journal of Urology, Vol.16, No.1, pp. 4458-4462, 2009
Abstract Introduction: Premature ejaculation (PE) is a common sexual dysfunction. Treatment ranges from behavior modification to systemic and topical pharmacological treatments. Results to date have been generally inconsistent and of limited effectiveness. New avenues of therapy are needed.
Aim: To investigate the effect of extracorporeal functional magnetic stimulation (FMS) as a noninvasive treatment for men with PE.
Methods: The NeoControl System for FMS was used in the study. Baseline assessment included: history and physical, medications, hormonal assessment and intravaginal ejaculatory latency time (IVELT) by stopwatch determination. Treatment involved a first phase of five biweekly sessions (primary outcome). Men who… More >

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ARTICLE

Eric C. Sayre^1,2, Peter S. Bunting^3,4, Jacek A. Kopec^2,5
Canadian Journal of Urology, Vol.16, No.1, pp. 4463-4471, 2009
Abstract Introduction: Medical chart-review and self-reported questionnaire are two common methods of determining cancer screening and symptoms. We investigate the validity of these methods and therefore of a class of clinical/epidemiological studies. We compare variables on prostate cancer, any prostate-specific antigen (PSA) test, asymptomatic screening PSA, any digital rectal exam (DRE), and urinary symptoms. We used data from a 2005 case control study of PSA and metastatic prostate cancer (MPC) (253 cases and 496 controls). Data were collected from 1999 to 2002.
Methods: We calculated kappa, percent agreement (PPA) and prevalence adjusted bias adjusted kappa (PABAK). We compared… More >

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ARTICLE

Michaël Peyromaure^1,2, Kaili Mao^1,2, Yinghao Sun^2,3, Shujie Xia⁴, Nin Jiang⁵, Shiqing Zhang⁶, Gongxian Wang⁷, Zhongmin Liu², Bernard Debré^1,2
Canadian Journal of Urology, Vol.16, No.1, pp. 4472-4477, 2009
Abstract Objective: To compare the detection and management of prostate cancer in one French and six Chinese urological institutions.
Patients and methods: All the patients subjected to prostate biopsy for suspected prostate cancer in six Chinese urological institutions and in the department of urology of the Cochin hospital, France, between January 2003 and December 2005 were included. The characteristics of patients and tumors, and the management of prostate cancer were then analyzed.
Results: In the Chinese institutions, 95.8% of patients undergoing prostate biopsy presented with urinary disorders. The rate of abnormal digital rectal examination (DRE) ranged from 29.2% to… More >

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ARTICLE

Ammar Hameed¹, Ali Thwaini^1,2, Zeeshan Aslam¹, Iqbal Shergill¹, Raed Ahmed³, Ghada Yahia³, Donald Morgan²
Canadian Journal of Urology, Vol.16, No.1, pp. 4478-4483, 2009
Abstract Objectives: To assess the relation of sex hormone levels in men, as measured by Free Androgen Index (FAI), with severity of erectile dysfunction (ED) and with their response to treatment.
Methods: We retrospectively reviewed the medical records of men who consecutively attended the urology clinic with the complaint of ED between March 2004 and October 2007. The Sexual Health Inventory for Men (SHIM) score was used as the main outcome measure in this study, and its variation was tested by certain variables using the Epi Info software.
Results: A total of 150 men were studied. The majority of… More >

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ARTICLE

David E. Rapp¹, Lambda P. Msezane¹, W. Stuart Reynolds¹, Tamara L. Lotan², Piotr Obara¹, R. Corey O’Connor³, Jerome B. Taxy², Glenn S. Gerber¹, Gregory P. Zagaja¹
Canadian Journal of Urology, Vol.16, No.1, pp. 4484-4489, 2009
Abstract Objectives: We sought to evaluate the ability of biopsy core recutting to increase cancer detection in patients with high grade prostatic intraepithelial neoplasia (HGPIN).
Methods: This prospective study encompasses all patients undergoing 12 core TRUS guided prostate biopsy between February 2004 and January 2007. In patients with HGPIN on initial biopsy, the paraffin blocks were resampled for cancer by additional deeper levels per core. Additional analysis was performed in the patients with HGPIN in order to detect whether significant differences in prebiopsy variables were associated with patients subsequently found to have benign versus carcinoma on recutting. Last,… More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Jamil Rehman¹, Bilal Chughtai², Khurshid Guru³, Ridwan Shabsigh⁴, David B. Samadi⁵
Canadian Journal of Urology, Vol.16, No.1, pp. 4490-4494, 2009
Abstract Objective: To present our technique for the management of an enlarged median lobe when the ureteral orifices are close to the bladder neck during robotic-assisted radical prostatectomy.
Materials and methods: From January 2005 to January 2007, we performed over 600 robotic assisted radical prostatectomies. We had 63 patients (10%) with enlarged median lobes. Of these patients, two (5.7%) had their ureteral orifices in close proximity to the bladder neck. An additional patient, without a median lobe, had his orifices very close to the bladder neck. To aid in the management of their median lobes, all three patients… More >

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CASE REPORT

Mohamed A. Elshaikh¹, Willie Underwood², Daniel E. Soto¹
Canadian Journal of Urology, Vol.16, No.1, pp. 4495-4497, 2009
Abstract We report a case history of a patient with Parkinson’s disease (PD) treated with androgen deprivation therapy (ADT) and external beam radiation for prostate cancer, who developed severe deterioration of his PD during ADT. More >

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CASE REPORT

Andre van der Merwe, Amir Zarrabi, Jaques Basson, Johan Stander, Chris F. Heyns
Canadian Journal of Urology, Vol.16, No.1, pp. 4498-4501, 2009
Abstract Penile cancer normally spreads in a predictable manner to the regional lymph nodes: first inguinal and then the pelvic nodes. We report a case where the patient presented synchronously with secondary skin metastases and primary high grade penile squamous carcinoma. In addition the patient also had pulmonary metastases, locoregional spread to the groin nodes, liver metastases and tumour erosion of a right sided rib. The skin metastases appeared nodular, were firm in consistency and appeared intradermal. Skin metastases have been described for a number of solid malignancies – the clinician must have an index of More >

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EDITORIAL COMMENT

Paul K. Hegarty
Canadian Journal of Urology, Vol.16, No.1, pp. 4501-4501, 2009
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CASE REPORT

Gustavo de la Roza¹, Asghar Naqvi¹, Kimball Clark²
Canadian Journal of Urology, Vol.16, No.1, pp. 4502-4506, 2009
Abstract Gastrointestinal stromal tumors (GISTs) are a rare and heterogeneous group of spindle cell neoplasms that have also been reported outside of gastrointestinal (GI) tract. These tumors are characterized by somatic mutations of c-KIT (CD117), a proto-oncogene that encodes a receptor tyrosine kinase normally expressed in the interstitial cell of Cajal that control the GI smooth muscle peristalsis, and an exquisite sensitivity to the action of the tyrokinase inhibitor imatinib mesylate (STI571; Gleevec). We report two cases of gastrointestinal stromal tumor identifi ed on prostatic biopsies, where a primary prostatic sarcoma was considered in the differential… More >

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RESIDENT’S CORNER

Bruce L. Jacobs, Erin P. Gibbons, Bishoy A. Gayed, Joseph L. Whetstone, Ronald L. Hrebinko, Jr.
Canadian Journal of Urology, Vol.16, No.1, pp. 4507-4511, 2009
Abstract Objectives: The presentation of synchronous bilateral renal lesions is rare. We report our experience with the surgical management of these lesions in both a single and staged procedure.
Methods: We retrospectively reviewed the records of all patients with bilateral synchronous renal lesions who underwent surgical management by one surgeon between 2000-2007. We compared characteristics including pre and postoperative renal function, complication rates, and oncological outcomes between the single and staged cohorts. Data were analyzed using descriptive statistics, Student's t-test, and Fisher's exact test.
Results: A total of 26 patients (73% male, mean age 65.5 ± 12.2 years) with… More >

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RESIDENT’S CORNER

Trinity J. Bivalacqua¹, Herman S. Bagga¹, Kaustubha Patil¹, Ahmed Magheli¹, Janis M. Taube², Thomas J. Guzzo¹, Mark L. Gonzalgo¹
Canadian Journal of Urology, Vol.16, No.1, pp. 4512-4515, 2009
Abstract Carcinosarcoma (CS) of the bladder is a rare malignancy of the genitourinary tract that is highly aggressive with unfavorable prognoses. Data regarding the epidemiological and clinicopathological characteristics of CS of the urinary bladder have been limited due to the low reported incidence of the tumor. In particular, there is little evidence on recurrence patterns and surveillance after definitive surgical therapy. In this case report, we describe a urethral recurrence of CS after radical cystoprostatectomy for CS of the bladder. The goal of this case report is to review our current understanding of the pathological and More >

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RESIDENT’S CORNER

Mark Tyson¹, Margaret French^1,4, Nancy McNulty^1,3, Lori Lerner^1,2
Canadian Journal of Urology, Vol.16, No.1, pp. 4516-4518, 2009
Abstract Angiosarcomas are soft tissue malignancies of connective tissue origin with rapid hematogenous spread, but are extremely uncommon primary tumors of the bladder with approximately ten reported cases in the 20th century. We report a 59-year-old man with benign prostatic hyperplasia (BPH) and gross hematuria who underwent a bladder biopsy for a markedly thickened bladder wall on CT scan. Biopsy specimens demonstrated deep vascular malformations that were concerning for a malignancy. Intense pathological review was initially not defi nitive and transurethral resection of the prostate (TURP) was performed for his symptoms. Interestingly, surgery reversed the bladder More >

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RESIDENT’S CORNER

Anne K. Mongiu, Brain T. Helfand, Stephanie J. Kielb
Canadian Journal of Urology, Vol.16, No.1, pp. 4519-4521, 2009
Abstract Suprapubic tube placement is a common urological procedure with a low incidence of complications, including hematuria, catheter blockage, recurrent urinary tract infections, and rarely, injury to adjacent organs. Fortunately, most serious complications are discovered shortly after initial suprapubic tube placement and are readily corrected. Very few cases of delayed complications or injuries have been reported. We report a case of Foley perforation into the ileum during suprapubic tube exchange discovered more than 8 months after initial placement, and preceding numerous monthly changes that occurred without incident. While a rare complication, physicians should be conscious of More >

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CLINICAL TRIALS

Richard W. Casey¹, Jack Barkin²
Canadian Journal of Urology, Vol.16, No.1, pp. 4522-4523, 2009
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CLINICAL TRIALS

George Rodrigues, Mary J. Mackenzie, Eric Winquist
Canadian Journal of Urology, Vol.16, No.1, pp. 4524-4530, 2009
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