Open Access

LEGENDS IN UROLOGY

Ian M. Thompson
Canadian Journal of Urology, Vol.29, No.1, pp. 10956-10958, 2022
Abstract This article has no abstract. More >

View

32

Download

34

Open Access

BOOK REVIEW

Ashok Agarwal, Ahmad Majzoub, Sandro C Esteves
Canadian Journal of Urology, Vol.29, No.1, pp. 10959-10959, 2022
Abstract This article has no abstract. More >

View

27

Download

31

Open Access

ARTICLE

Peter J. Gilling¹, Neil Barber², Mohamed Bidair³, Paul Anderson⁴, Mark Sutton⁵, Tev Aho⁶, Eugene Kramolowsky⁷, Andrew Thomas⁸, Ronald P. Kaufman, Jr.⁹, Gopal Badlani¹⁰, Mark Plante¹¹, Mihir Desai¹², Leo Doumanian¹², Alexis E. Te¹³, Claus G Roehrborn¹⁴
Canadian Journal of Urology, Vol.29, No.1, pp. 10960-10968, 2022
Abstract Introduction: To determine if Aquablation therapy can maintain long term effectiveness in treating men with moderate to severe lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) with a baseline prostate volume between 30 and 80 mL at 5 years compared to TURP.
Materials and methods: In a double-blinded, multicenter prospective randomized controlled trial, 181 patients with moderate to severe LUTS secondary to BPH underwent TURP or Aquablation. The primary efficacy endpoint was reduction in International Prostate Symptom Score (IPSS) at 6 months. The primary safety endpoint was the occurrence of Clavien-Dindo persistent Grade 1… More >

View

31

Download

36

Open Access

ARTICLE

Paul H. Chung¹, Andrew Salib¹, Taylor Tidwell¹, Kaitlin Berry¹, Joon Yau Leong¹, Rosemary Frasso²
Canadian Journal of Urology, Vol.29, No.1, pp. 10969-10975, 2022
Abstract Introduction: Prior studies evaluating the efficacy of penile prostheses (PP) and intracavernosal injections (ICI) have focused predominantly on sexual function, not psychosocial health. We utilized the freelisting technique and the Self-Esteem and Relationship (SEAR) questionnaire to evaluate the impact of PP and ICI treatments on psychosocial functioning.
Materials and methods: IRB-approval was obtained to perform an evaluation of patients who underwent PP or ICI treatment for erectile dysfunction (ED). Using a modified freelisting approach, participants were asked to give three one-word responses to questions about sexual function and relationships. Participants also completed the SEAR questionnaire and results… More >

View

27

Download

31

Open Access

ARTICLE

Irini Youssef^1,2, Michael Poch³, Natarajan Raghunand³, Julio Pow-Sang³, Peter A. S. Johnstone³
Canadian Journal of Urology, Vol.29, No.1, pp. 10976-10978, 2022
Abstract Introduction: To evaluate the use of preoperative magnetic resonance imaging (MRI) as a predictor of positive margins after radical prostatectomy (RP). This is important as such patients may benefit from postoperative radiotherapy. With the advent of preoperative MRI, we posited that pelvimetry could predict positive margins after RP in patients with less-than ideal pelvic dimensions undergoing robotic-assisted laparoscopic surgery.
Materials and methods: After IRB approval, data from patients undergoing RP at our center between 1/1/2018 and 12/31/2019 (n = 314) who had undergone prior prostate MRI imaging (n = 102) were analyzed. All RPs were performed using… More >

View

27

Download

31

Open Access

COMMENTARY

Joseph R. Wagner
Canadian Journal of Urology, Vol.29, No.1, pp. 10979-10979, 2022
Abstract This article has no abstract. More >

View

27

Download

30

Open Access

ARTICLE

Dylan M. Buller¹, Tara McLaughlin², Ilene Staff³, Kevin Pinto², Akshay Gangakhedkar², Joseph Tortora³, Guy Manetti⁴, Joseph R. Wagner²
Canadian Journal of Urology, Vol.29, No.1, pp. 10980-10985, 2022
Abstract Introduction: The current utility of MRI-fusion targeted biopsy as either an adjunct to or replacement for systematic template biopsy for the detection of clinically significant prostate cancer is disputed. The purpose of this study is to assess the current effectiveness of MRI-targeted versus systematic template prostate biopsies at two institutions and to consider possible underlying factors that could impact variability between detection rates in our patient population compared to others.
Materials and methods: A retrospective review from our prospectively maintained prostate cancer databases was conducted. Patients with prostate MRI lesions (PI-RADSv2) receiving concurrent systematic 12-core and MRI-fusion… More >

View

25

Download

30

Open Access

ARTICLE

Cédric Charrois-Durand¹, Daniel Taussky¹, Guila Delouya¹, Daniel Liberman²
Canadian Journal of Urology, Vol.29, No.1, pp. 10986-10991, 2022
Abstract Introduction: To analyze biochemical failure-free survival and erectile dysfunction (ED) in younger men treated with prostate seed brachytherapy (PB).
Materials and methods: Included were patients ≤ 55 years treated with PB. Erectile function at baseline and after treatment were assessed using the physician-reported CTCAE version 4.0. Biochemical failure (BF) was defined according to the Phoenix Consensus definition (PSA nadir + 2 ng/mL). The log-rank test (Kaplan-Meier method) and cox-regression analysis was used to calculate BF-free survival.
Results: Between July 2005 and November 2020, a total of 137 patients ≤ 55 years (range 44-55 years old) were treated with… More >

View

30

Download

37

Open Access

ARTICLE

Sijun Liu^1,2, Zongwei Wang¹, Xingbo Long³, Aaron Fleishman¹, Xiangchun Huang⁴, Qingguang Wu², Boris Gershman¹, Aria F. Olumi¹
Canadian Journal of Urology, Vol.29, No.1, pp. 10992-11002, 2022
Abstract Introduction: To determine whether marital status combined with race serve as prognostic factors for survival in localized prostate cancer.
Materials and methods: Patients with localized prostate cancer were retrospectively extracted from the Surveillance, Epidemiology, and End Results (SEER) database. Chi-square test was used to investigate the association between marital status combined with race and other variables. Gray’s test was used to compare the cumulative incidence function of different variables. Multivariable analysis was conducted to assess prognostic factors after adjusting for other variables.
Results: A total of 207,219 patients with localized prostate cancer from the SEER database from 2010… More >

View

28

Download

32

Open Access

COMMENTARY

Judd W. Moul
Canadian Journal of Urology, Vol.29, No.1, pp. 11003-11004, 2022
Abstract This article has no abstract. More >

View

25

Download

29

Open Access

ARTICLE

Michael Uy¹, Richard Di Lena¹, Jen Hoogenes^1,2, Badr Al-Harbi³, Aidan Woodward⁴, Bobby Shayegan^1,2, Edward D. Matsumoto^1,2
Canadian Journal of Urology, Vol.29, No.1, pp. 11005-11011, 2022
Abstract Introduction: The relationship between obesity and nephrolithiasis is a well-documented phenomenon. Visceral adipose tissue (VAT) has been proposed to be an accurate indicator of metabolic derangement. We present a study that investigates the relationship between computed tomography (CT) delineated VAT measurements and 24-hour urine (24 HU) profiles in the context of profound weight loss.
Materials and methods: A total of 86 patients with a history of nephrolithiasis who underwent bariatric surgery were reviewed. All patients had pre and postoperative 24 HU analysis and CT kidney and urinary bladder performed. CT-based fat delineation program, AnalyzePro, was used to… More >

View

30

Download

39

Open Access

ARTICLE

Tyler Overholt^1,2, Robert J. Evans¹, Gopal Badlani¹, Catherine A. Matthews¹, Stephen J. Walker^1,2
Canadian Journal of Urology, Vol.29, No.1, pp. 11012-11019, 2022
Abstract Introduction: To further facilitate understanding of disease pathophysiology and patient stratification in interstitial cystitis/bladder pain syndrome (IC/BPS), we utilized molecular phenotyping to compare three clinically distinct IC/BPS patient subgroups.
Materials and methods: Total RNA (miRNA and mRNA) was isolated via standard protocols from IC/BPS patient bladder biopsies and assayed on whole genome and microRNA expression arrays. Data from three patient subgroups (n = 4 per group): (1) low bladder capacity (BC; ≤ 400 cc) without Hunner’s lesion, (2) low BC with Hunner’s lesion, and (3) non-low BC (> 400 cc) were used in comparative analyses to evaluate… More >

View

29

Download

39

Open Access

ARTICLE

Daniel Cardoso, Armando Rosales, David D. Thiel, Horacio Asbun, John A. Stauffer
Canadian Journal of Urology, Vol.29, No.1, pp. 11020-11023, 2022
Abstract Introduction: Renal cell carcinoma (RCC) is the most common primary neoplasia that metastasizes to the pancreas. Pancreatic metastasis (PM) occur in asymptomatic older patients and are identified during follow up. If resectable, surgery is the treatment of choice for long term survival. Our goal is to analyze outcomes of patients with RCC-PM.
Material and methods: We reviewed all patients with metastatic RCC (mRCC) who underwent resection, from known primary RCC and RCC-PM.
Results: There were 16 patients (mean age of 67 ± 8 years, male 8 (50%), mean BMI 29 ± 5.36 kg/m2). Half of them were asymptomatic.… More >

View

28

Download

33

Open Access

MINI REVIEW

Kevin A. Diaz¹, Philippe E. Spiess^2,3,4, Andrea Necchi⁵, Roger Li², Marco Bandini⁶, Herney Andrés García-Perdomo^1,7
Canadian Journal of Urology, Vol.29, No.1, pp. 11024-11026, 2022
Abstract Research is very competitive but vital in medical training at all levels and disciplines. Given the evidence-based practice, people are reinforced to adopt a constant change attitude and critically appraise all the literature to make the best medical decisions. Nonetheless, the motivation to generate new knowledge and scientific research is relegated to small groups due to multiple factors. Such as the lack of research education from early stages in medical training, the absence of early results, and the lack of mentors willing to sponsor a person who wants to begin this way. This mini review More >

View

26

Download

33

Open Access

RESIDENT’S CORNER

M. Ryan Farrell, Lawrence T. Zhang, Alex J. Vanni
Canadian Journal of Urology, Vol.29, No.1, pp. 11027-11031, 2022
Abstract Duplicated anterior urethras are a rare congenital anomaly that is exceedingly uncommon among adult patients, as surgical correction is often completed during childhood. We present the case of a 33-year-old man with uncorrected duplicated anterior urethras and urinary retention due to severe urethral stricture disease involving both of his uncorrected duplicated anterior urethras. This report highlights an operative management strategy for reconstruction to create a single, unobstructed urethra that terminates in an orthotopic meatus. Further, we provide an overview of the anatomic variants of urethral duplication. More >

View

29

Download

29

Open Access

RESIDENT’S CORNER

Jacob R. Stephens¹, Kenneth M. Peters^1,2
Canadian Journal of Urology, Vol.29, No.1, pp. 11032-11035, 2022
Abstract Vulvodynia is a debilitating disorder which can prove extremely difficult to treat. Neuromodulation is increasingly becoming a frontline therapy in various chronic pain syndromes. We present a relatively simple surgical technique utilizing targeted neuromodulation leading to the successful treatment of vulvodynia. More >

View

28

Download

33

Open Access

RESIDENT’S CORNER

Zachary Snow¹, Lauren S. Jones², Javier Piraino¹, Matthew Sterling¹
Canadian Journal of Urology, Vol.29, No.1, pp. 11036-11039, 2022
Abstract Lymphoma of the urinary bladder is quite rare, accounting for a small percentage of all bladder neoplasms. Here we discuss the case of a 68-year-old male patient who initially presented with acute renal failure and severe bilateral hydronephrosis on ultrasound. Cross-sectional imaging further revealed a diffusely thickened bladder wall with extensive retroperitoneal and mesenteric lymphadenopathy. Bladder biopsies ultimately led to a diagnosis of stage IV chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). This is a rare instance of upper tract dilatation being the first sign of a widely disseminated hematologic malignancy. More >

View

30

Download

34