Open Access

EDITORIAL

Jack Barkin
Canadian Journal of Urology, Vol.22, No.3, pp. 7767-7767, 2015
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LEGENDS IN UROLOGY

Demetrius H. Bagley
Canadian Journal of Urology, Vol.22, No.3, pp. 7768-7771, 2015
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ARTICLE

Claus G. Roehrborn¹, Daniel B. Rukstalis², Jack Barkin³, Steven N. Gange⁴, Neal D. Shore⁵, Jonathan L. Giddens⁶, Damien M. Bolton⁷, Barrett E. Cowan⁸, Anthony L. Cantwell⁹, Kevin T. McVary¹⁰, Alexis E. Te¹¹, Shahram S. Gholami¹², William G. Moseley¹³, Peter T. Chin¹⁴, William T. Dowling¹⁵, Sheldon J. Freedman¹⁶, Peter F. Incze¹⁷, K. Scott Coffield¹⁸, Fernando D. Borges¹⁹, Prem Rashid²⁰
Canadian Journal of Urology, Vol.22, No.3, pp. 7772-7782, 2015
Abstract Introduction: To report the three year results of a multi-center, randomized, patient and outcome assessor blinded trial of the Prostatic Urethral Lift (PUL) in men with bothersome lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).
Materials and methods: At 19 centers in North America and Australia, 206 subjects ≥50 years old with International Prostate Symptom Score (IPSS) ≥13, peak flow rate (Qmax) ≤12 mL/s, and prostate volume between 30cc-80cc were randomized 2:1 to the PUL procedure or sham control. PUL involved placing permanent UroLift implants into the lateral lobes of the prostate to… More >

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ARTICLE

Nazneen Fatima¹, Daniel J. Canter^2,3, Bradley C. Carthon^4,6, Omer Kucuk^4,6, Viraj A. Master^5,6, Peter T. Nieh^5,6, Kenneth Ogan^5,6, Adeboye O. Osunkoya^1,5,6
Canadian Journal of Urology, Vol.22, No.3, pp. 7783-7787, 2015
Abstract Introduction: Sarcomatoid urothelial carcinoma is a dedifferentiated biphasic tumor that exhibits morphological and/or immunohistochemical evidence of epithelial and mesenchymal differentiation. In this series, we analyzed the clinicopathologic features of this rare variant of urothelial carcinoma.
Materials and methods: A search was made through our surgical pathology files and consultation files of the senior author for cases of sarcomatoid urothelial carcinoma of the bladder from 2005-2014. All the slides were retrieved and re-reviewed, and clinical data was also obtained including follow up.
Results: Thirty-seven cases of sarcomatoid urothelial carcinoma of the bladder were identified. Mean patient age… More >

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ARTICLE

Clinton D. Bahler¹, K. Clint Cary¹, Swapnil Garg¹, Eric M. DeRoo¹, Christian H. Tabib¹, Jagan K. Kansal¹, M. Francesca Monn¹, Chandra K. Flack¹, Timothy A. Masterson¹, M. Kumar Sandrasegaran², Richard S. Foster¹, Chandru P. Sundaram¹
Canadian Journal of Urology, Vol.22, No.3, pp. 7788-7796, 2015
Abstract Introduction: To assess whether volumetric measurements can differentiate functional changes between reconstructive techniques after partial nephrectomy.
Materials and methods: One hundred and fifty-six patients undergoing partial nephrectomy for a single renal mass were retrospectively studied between 2008 and 2012. Computed tomography scans were available for volume calculations on 56 (18 non-renorrhaphy and 38 renorrhaphy). Institutional review board approval was obtained. The primary outcome was % volume loss in the operated kidney, which was calculated from three-dimensional reconstructions using a semiautomatic segmentation algorithm. Multivariable regression and propensity score analysis was performed.
Results: Volumetric analysis detected a difference… More >

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COMMENTARY

Jay D. Raman
Canadian Journal of Urology, Vol.22, No.3, pp. 7797-7797, 2015
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ARTICLE

Noriko Ninomiya, Satoshi Tamada, Minoru Kato, Takeshi Yamasaki, Taro Iguchi, Tatsuya Nakatani
Canadian Journal of Urology, Vol.22, No.3, pp. 7798-7804, 2015
Abstract Introduction: We investigated therapeutic outcomes in consecutive patients with metastatic renal cell carcinoma treated with targeted anticancer agents from 2008 to 2014 in order to determine the efficacy of adverse event management for such agents and the best sequence in which to use them.
Materials and methods: We analyzed 132 consecutive patients who had taken targeted anticancer agents for metastatic renal cell carcinoma. Of these, 101 patients received therapy between 2008 and 2011 (pioneer group) and 31 patients received therapy between 2011 and 2014 (contemporary group). Patients of the contemporary group were provided with aggressive adverse… More >

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COMMENTARY

Ryuta Tanimoto
Canadian Journal of Urology, Vol.22, No.3, pp. 7805-7805, 2015
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ARTICLE

Casey A. Dauw, Gary J. Faerber, John M. Hollingsworth, III, J. Stuart Wolf, Jr.
Canadian Journal of Urology, Vol.22, No.3, pp. 7806-7810, 2015
Abstract Introduction: Ureteral obstruction due to extrinsic compression is associated with significant morbidity and mortality. Management options for this condition include renal drainage with percutaneous nephrostomy (PCN) or internal ureteral stent placement. A significant portion of patients will have disease progression leading to internal stent obstruction which is almost uniformly managed with PCN. We evaluated a novel, wire-reinforced internal ureteral stent as an alternative to PCN in those patients who fail initial internal ureteral stent placement.
Materials and methods: A retrospective chart review was performed to identify patients with extrinsic ureteral obstruction that failed conventional plastic internal… More >

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ARTICLE

Jeannine Marie Miranne¹, Aurora Dominguez², Andrew Ian Sokol¹, Robert Eric Gutman¹, Cheryl Bernadette Iglesia¹
Canadian Journal of Urology, Vol.22, No.3, pp. 7811-7816, 2015
Abstract Introduction: Our objective was to evaluate whether foley catheter guide use decreased the risk of cystotomy and urethrotomy during retropubic midurethral sling placement.
Materials and methods: This retrospective cohort study included all women undergoing retropubic synthetic midurethral sling placement at a single academic institution between January 2011 and September 2012. Patients were divided into groups based on whether or not the foley catheter guide was used during surgery. The primary outcome was the incidence of cystotomy.
Results: A total of 310 patients underwent retropubic midurethral sling placement. The foley catheter guide was used in 76/310 cases… More >

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ARTICLE

Domenic Di Rollo¹, Aza Mohammed², Alexander Rawlinson¹, Jayne Douglas-Moore³, John Beatty³
Canadian Journal of Urology, Vol.22, No.3, pp. 7817-7823, 2015
Abstract Introduction: The principles of enhanced recovery after surgery (ERAS) protocols have been developed to optimize care and facilitate recovery after major surgery. The purpose of this systematic review is to present an upto-date assessment of the perioperative cares in complex urological surgery from the available evidence and ERAS group recommendations.
Materials and methods: Systematic searches of PubMed, Embase, Cochrane library and conference abstracts and bibliographies databases.
Results: A total of six studies were identified that met the inclusion criteria. Two examined the role of ERAS in radical cystectomy, and the rest examined its role in renal surgery More >

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RESIDENT’S CORNER

Ramin Behzadigohar, Mark A. Rosenthal, Ben Tran
Canadian Journal of Urology, Vol.22, No.3, pp. 7824-7826, 2015
Abstract We report a case of an 82-year-old man with renal cell carcinoma who developed a cardiac metastasis within the interventricular septum. He had been under watchful waiting for indolent metastatic renal cell carcinoma for many years before developing symptoms consistent with heart failure. At this time, a 44 mm interventricular septal mass, consistent with a cardiac metastasis, was identified as the cause of his symptoms. Pazopanib was initiated which led to both a clinical and radiological response. More >

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RESIDENT’S CORNER

Steven Kheyfets, Waleed Eisa, Heinric Williams
Canadian Journal of Urology, Vol.22, No.3, pp. 7827-7829, 2015
Abstract We present a case report of testicular seminoma with intraluminal metastasis to the ureter causing obstruction and hydronephrosis. To our knowledge, this is the fourth case to be reported in the world literature of metastatic tumor to the ureter from a primary testicular seminoma. More >

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RESIDENT’S CORNER

Dayron Rodríguez¹, Kristine M. Cornejo², Peter M. Sadow², Yahir Santiago-Lastra¹, Adam S. Feldman¹
Canadian Journal of Urology, Vol.22, No.3, pp. 7830-7833, 2015
Abstract Myopericytoma is a low grade spindle cell neoplasm largely occurring in skin. We describe the first reported case of a penile myopericytoma. Histologically, the penile tumor was composed of a perivascular proliferation of tumor cells with ovoid shaped nuclei and abundant eosinophilic cytoplasm. Immunohistochemically, the tumor was reactive for markers of smooth muscle differentiation and vascular differentiation. The tumor was noted to be negative for BRAF by immunohistochemistry and wild-type upon gene sequencing using SnaPshot. Our finding serves to expand the anatomical distribution of myopericytoma and broadens the spectrum of primary mesenchymal neoplasms that may More >

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RESIDENT’S CORNER

Andrew Cohen¹, Rodrigo Ledezma-Rojas¹, Ernest Mhoon², Gregory Zagaja¹
Canadian Journal of Urology, Vol.22, No.3, pp. 7834-7835, 2015
Abstract Bilateral bloody otorrhea is a rare complication of surgery and to our knowledge a previously unpublished event. We review the case of a 50-year-old male who underwent robotic-assisted laparoscopic radical prostatectomy (RALP) with bilateral lymphadenectomy for Gleason’s Score 4 + 4 = 8 prostate cancer. Bloody discharge from bilateral auditory canals was noted upon removal of the surgical drapes. Otolaryngologic examination revealed bilateral anterior auditory canal hematomas without any loss of hearing. Steep Trendelenburg position in combination with perioperative anticoagulants may have contributed to this complication. Given the rarity of this event no specific risk More >

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HOW I DO IT

Dean S. Elterman
Canadian Journal of Urology, Vol.22, No.3, pp. 7836-7843, 2015
Abstract The treatments for benign prostate enlargement (BPE), also known as lower urinary tract symptoms secondary to benign prostatic hypertrophy (BPH-LUTS), have evolved significantly over recent years. Where transurethral resection of the prostate (TURP) has been the gold standard surgery for enlarged prostate glands < 80 grams, newer modalities such as laser technology have proliferated with safe and efficacious results. Notably, for prostates larger than 80-100 grams, the surgical options were an open, simple prostatectomy or perhaps a staged TURP. Both of these surgeries have the potential for bleeding complications, electrolyte abnormalities, and prolonged hospital admissions.… More >

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HOW I DO IT

Ken Faber, Debra Fromer
Canadian Journal of Urology, Vol.22, No.3, pp. 7844-7846, 2015
Abstract This article details recommendations on minimizing complications in pelvic foor reconstruction using mesh. It is designed to incorporate real world experience from an expert urologist in female pelvic foor reconstruction with medical literature and prevailing theories. More >

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MEETING REVIEW

Jack Barkin
Canadian Journal of Urology, Vol.22, No.3, pp. 7847-7852, 2015
Abstract Several abstracts presented at the 2015 European Association of Urology Meeting highlighted new developments in hormone therapy for prostate cancer management. One abstract described how the luteinizing hormone-releasing hormone (LHRH)/gonadotropin-releasing hormone (GnRH) agonist leuprolide, but not the LHRH/GnRH antagonist degarelix, induced plaque instability in a mouse model. A second abstract showed that in patients with a history of severe cardiovascular disease, degarelix was associated with fewer cardiovascular events than treatment with an LHRH agonist. A third abstract showed how primary androgen-deprivation therapy was linked with increased all-cause mortality in a US registry. A fourth abstract More >

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