Open Access

EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.20, No.2, pp. 6668-6668, 2013
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LEGENDS IN UROLOGY

Imre Romics
Canadian Journal of Urology, Vol.20, No.2, pp. 6669-6671, 2013
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REVIEW

Graham Sommer¹, Donna Bouley², Harcharan Gill³, Bruce Daniel¹, Kim Butts Pauly¹, Chris Diederich⁴
Canadian Journal of Urology, Vol.20, No.2, pp. 6672-6681, 2013
Abstract Introduction: There is currently a great deal of interest in the possible use of focal therapies for prostate cancer, since such treatments offer the prospect for control or cure of the primary disease with minimal side effects. Many forms of thermal therapy have been proposed for focal ablation of prostate cancer, including laser, high intensity ultrasound and cryotherapy. This review will demonstrate the important roles that magnetic resonance imaging (MRI) guidance can offer to such focal ablation, focusing on the use of high intensity ultrasonic applicators as an example of one promising technique.
Materials and methods: Transurethral… More >

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ARTICLE

Susan S. Garfield¹, Meghan B. Gavaghan¹, Shannon O. Armstrong¹, J. Stephen Jones²
Canadian Journal of Urology, Vol.20, No.2, pp. 6682-6689, 2013
Abstract Introduction: Several studies, including the recently published phase III study by Stenzl and colleagues, have demonstrated that hexaminolevulinate hydrochloride, when used with blue light fluorescence cystoscopy, improves detection of non-muscle invasive bladder tumors compared to white light cystoscopy and transurethral resection of bladder tumors (TURB) alone.
Materials and methods: The objective of this study was to conduct a detailed assessment of the cost-effectiveness of using hexaminolevulinate hydrochloride with blue light cystoscopy as an adjunct to white light versus white light cystoscopy alone at the time of initial TURB in the United States. A probabilistic decision tree model, More >

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ARTICLE

James Lin, Michael Whalen, Dara Holder, Gregory Hruby, G. Joel DeCastro, James McKiernan
Canadian Journal of Urology, Vol.20, No.2, pp. 6690-6695, 2013
Abstract Introduction: We examined the effects of neoadjuvant chemotherapy (NC) in the treatment of muscle invasive urothelial carcinoma of the bladder in those with mixed histology (MH) versus those with pure urothelial carcinoma (UC).
Materials and methods: Between 2000 and 2012, 195 patients were identified with clinical stage T2–T4, N0–Nx, M0–Mx UCB who had either NC (± radical cystectomy) (n = 63) or radical cystectomy (RC) alone (n = 132). Tumors were classified as either pure UC or MH. Endpoints included downstaging to pT0 and overall survival. Multivariable Cox regression and the Kaplan-Meier method were used to estimate… More >

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ARTICLE

Carlos H. Martinez¹, Andrew K. Williams¹, Joseph L. Chin¹, Larry Stitt², Jonathan I. Izawa¹
Canadian Journal of Urology, Vol.20, No.2, pp. 6696-6701, 2013
Abstract Introduction: Clinical variables with more accuracy to predict biologically insignificant prostate cancer are needed. We evaluated the combination of transrectal ultrasound-guided biopsy of the prostate (TRUSBx) pathologic and radiologic findings in their ability to predict the biologic potential of each prostate cancer.
Materials and methods: A total of 1043 consecutive patients who underwent TRUSBx were reviewed. Using pathologic criteria, patients with prostate cancer (n = 529) and those treated with radical prostatectomy (RP) (n = 147) were grouped as: “insignificant” (Gleason score ≤ 6, prostate-specific antigen (PSA) density ≤ 0.15 ng/mL, tumor in ≤ 50% of any… More >

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ARTICLE

Mark D. Tyson¹, Paul E. Andrews¹, David A. Etzioni², Robert G. Ferrigni¹, Mitchell R. Humphreys¹, Scott K. Swanson¹, Erik P. Castle¹
Canadian Journal of Urology, Vol.20, No.2, pp. 6702-6706, 2013
Abstract Introduction: To evaluate the influence of marriage on the survival outcomes of men diagnosed with prostate cancer.
Materials and methods: We examined 115,922 prostate cancer cases reported to the Surveillance, Epidemiology, and End Results (SEER) database between 1988 and 2003. Multivariate Cox regression techniques were used to study the relationship of marital status and prostate cancer-specific and overall mortality.
Results: Married men comprised 78% of the cohort (n = 91,490), while unmarried men (single, divorced, widowed, and separated) comprised 22% of the cohort (n = 24,432). Married men were younger (66.4 versus 67.8 years, p < 0.0001), more… More >

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ARTICLE

Tomislav P. Pejcic¹, Cane Dz. Tulic^1,2, Natasa V. Lalic³, Biljana D. Glisic³, Svetlana D. Ignjatovic^3,4, Biljana B. Markovic^2,5, Jovan B. Hadzi-Djokic⁶
Canadian Journal of Urology, Vol.20, No.2, pp. 6707-6713, 2013
Abstract Introduction: Urinary prostate-specific antigen (uPSA) can be used as an additional parameter of benign prostatic hyperplasia (BPH) progression.
Materials and methods: From January 2001 to December 2011, uPSA was determined in 265 patients with benign prostate. Based on total prostate volume (TPV), the patients with benign prostate were divided into two groups: TPV < 31 mL and TPV ≥ 31 mL. Additionally, three groups were formed according to MTOPS study criteria: non-progressive BPH group (TPV < 31 mL, PSA < 1.6 ng/mL, age < 62 yrs), intermediate group (one or two parameters {TPV, PSA, age} increased), and… More >

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ARTICLE

Brian Kunzel¹, William Small², Michael Goodman³, John Pattaras¹, Viraj Master¹, Kenneth Ogan¹
Canadian Journal of Urology, Vol.20, No.2, pp. 6714-6720, 2013
Abstract Introduction: To determine whether preoperative computed tomography (CT)-based renal parenchymal volume (RPV) measurements would be predictive of postoperative chronic kidney disease (CKD).
Materials and methods: From 2005 to 2010, 189 patients with preoperative CT imaging performed at Emory University Hospital underwent renal tumor surgery. Preoperative and postoperative renal function was determined by estimating glomerular filtration rate (GFR) using standard Cockcroft-Gault (CG) and Modification of Diet in Renal Disease (MDRD) equations. Preoperative CT-measured RPV was calculated to determine the association of predicted preserved renal parenchyma with postoperative renal function and the development of CKD (GFR < 60 mL/min/1.73 m²).
… More >

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ARTICLE

Joshua P. Holstead¹, B. Jill Williams¹, Alex Gomelsky^1,2
Canadian Journal of Urology, Vol.20, No.2, pp. 6721-6725, 2013
Abstract Introduction: Women with risk factors for surgical failure (advanced age, failed previous anti-incontinence surgery, intrinsic sphincter deficiency, and absence of urethral hypermobility) underwent acellular bovine dermis slings. We evaluate long-term outcomes and complications with this material.
Materials and methods: We retrospectively identified 41 women who completed 36-month postoperative follow-up. Preoperative evaluation included pelvic exam, SEAPI classification, and validated quality of life (QoL) questionnaires. Stress urinary incontinence (SUI) cure was defined as SEAPI (S) subset = 0 and negative cough-stress test. Perioperative data was abstracted from the hospital and office chart.
Results: The SUI cure rate was 80.5%. Most More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Wenli Zhuo, Jinqian Chai, Tingzhao Xu, Weizhen Wu, Shunliang Yang, Jianming Tan
Canadian Journal of Urology, Vol.20, No.2, pp. 6726-6729, 2013
Abstract Introduction: To report our preliminary techniques and experience with retroperitoneoscopic single-site renal pedicle lymphatic disconnection (RPSS-RPLD) in five patients with serious filarial chyluria.
Materials and methods: Between May 2010 and July 2011, five patients with serious filarial chyluria underwent RPSS-RPLD. In each patient, a 3 cm single incision was made between the 12th subcostal margin and posterior axillary line, and a homemade single multichannel port using a surgical glove and three conventional trocars was placed into the retroperitoneal space. The lymphatic disconnection procedure was similar to that of traditional open surgery.
Results: All operations were successfully completed without More >

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RESIDENT’S CORNER

Yakup Bostanci¹, Ender Ozden², Ekrem Akdeniz², Amir Kazzazi¹, Bedri Kandemir², Yarkin Kamil Yakupoglu², Bob Djavan¹
Canadian Journal of Urology, Vol.20, No.2, pp. 6730-6733, 2013
Abstract Primary testicular leiomyosarcoma is an extremely rare tumor, and, to the best of our knowledge, only 20 cases in adults have been reported in the literature to date. Herein, we present a case of a 68-year-old man who complained of left scrotal swelling for 2 months. Radiological examination revealed a left testicular tumor with no metastases to other organs. A left inguinal orchiectomy was carried out and histopathologic examination revealed an intratesticular leiomyosarcoma. The patient was treated successfully by orchiectomy and received no adjuvant therapy. During follow up until 12 months after surgery, there has More >

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RESIDENT’S CORNER

Ricardo Pereira e Silva¹, Tito Leitão¹, Lurdes Correia², Francisco Martins¹, José Palma dos Reis¹, Tomé Lopes¹
Canadian Journal of Urology, Vol.20, No.2, pp. 6734-6736, 2013
Abstract We present a case report of a 17-year-old patient with a large renal mass that was detected on a computed tomography scan during investigation for secondary hypertension. Radical nephrectomy was performed, and the morphologic and immunocytochemical findings were compatible with a diagnosis of monophasic synovial sarcoma of the kidney. A cytogenetic search for t(X;18) translocation was performed, which was negative. The patient underwent an ifosfamide-based chemotherapy regimen. During follow-up, a positron emission tomography scan showed increased 18F-fluorodeoxyglucose metabolism at the right femur. Although cancer cells were expected in the biopsy specimen, only fibrous dysplasia of More >

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RESIDENT’S CORNER

Robert M. Turner II^1,3, Jeffrey J. Tomaszewski^1,3, Janelle A. Fox^1,3, Csaba Galambos^2,3, Glenn M. Cannon Jr^1,3
Canadian Journal of Urology, Vol.20, No.2, pp. 6737-6738, 2013
Abstract A 10-year-old boy underwent a computed tomography (CT) scan for left flank pain following a fall. Imaging demonstrated a 5 cm left upper pole renal mass. Partial nephrectomy revealed metanephric adenofibroma, a benign stromal-epithelial tumor thought to represent a hyperdifferentiated, mature form of Wilms’ tumor. We briefly discuss the histopathology and management of this rare tumor. More >

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RESIDENT’S CORNER

Matthew A. Uhlman, Scott C. Pate, James A. Brown
Canadian Journal of Urology, Vol.20, No.2, pp. 6739-6741, 2013
Abstract The incidence of small renal masses (≤ 4 cm) has increased over the past three decades. Partial nephrectomy remains the standard for treatment of such lesions, but increased attention is being given to patients who may benefit from active surveillance, given the low risk of metastatic spread and traditionally slow growth rates. Patients with significant comorbidities and the elderly are often considered optimal candidates for surveillance. We present an 86-year-old female undergoing active surveillance for a 1.4 cm lesion that grew in diameter approximately 0.5 cm per year over 3 years, followed by explosive growth More >

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COMMENTARY

Jay D. Raman
Canadian Journal of Urology, Vol.20, No.2, pp. 6742-6742, 2013
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