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RESIDENT’S CORNER

Primary synovial sarcoma of the kidney with unusual follow up fndings

Ricardo Pereira e Silva¹, Tito Leitão¹, Lurdes Correia², Francisco Martins¹, José Palma dos Reis¹, Tomé Lopes¹

1 Department of Urology, Centro Hospitalar Lisboa Norte, EPE – Hospital de Santa Maria, Lisbon, Portugal
2 Department of Pathology, Centro Hospitalar Lisboa Norte, EPE – Hospital de Santa Maria, Lisbon, Portugal
Address correspondence to Dr. Ricardo Manuel Pereirae Silva, Centro Hospitalar Lisboa Norte, EPE – Hospital de Santa Maria – Serviço de Urologia, Avenida Egas Moniz, 1649-035 Lisbon, Portugal

Canadian Journal of Urology 2013, 20(2), 6734-6736.

Abstract

We present a case report of a 17-year-old patient with a large renal mass that was detected on a computed tomography scan during investigation for secondary hypertension. Radical nephrectomy was performed, and the morphologic and immunocytochemical findings were compatible with a diagnosis of monophasic synovial sarcoma of the kidney. A cytogenetic search for t(X;18) translocation was performed, which was negative. The patient underwent an ifosfamide-based chemotherapy regimen. During follow-up, a positron emission tomography scan showed increased 18F-fluorodeoxyglucose metabolism at the right femur. Although cancer cells were expected in the biopsy specimen, only fibrous dysplasia of the bone was found. The patient was disease-free at his 29-month follow-up check-up.

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Keywords

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