Home / Journals / CJU / Vol.28, No.2, 2021
Special Issues
  • Open AccessOpen Access

    EDITORIAL

    The Agony and Ecstasy of Prostate Cancer PSMA PET

    Leonard G. Gomella
    Canadian Journal of Urology, Vol.28, No.2, pp. 10574-10575, 2021
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    LEGENDS IN UROLOGY

    LEGENDS IN UROLOGY

    Fredric L. Coe
    Canadian Journal of Urology, Vol.28, No.2, pp. 10576-10579, 2021
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    EXPERT OPINION

    Is it time to offer True Minimally Invasive Treatments (TMIST) for BPH? – A review of office-based therapies and introduction of a new technology category

    Dean S. Elterman1, Kevin C. Zorn2, Bilal Chughtai3, Naeem Bhojani2
    Canadian Journal of Urology, Vol.28, No.2, pp. 10580-10583, 2021
    Abstract Introduction: The options for treating benign prostatic hyperplasia (BPH) beyond medication and traditional transurethral surgery continue to expand. Undesirable side effects of medication and surgeries have driven interest toward minimally invasive surgical therapies (MISTs), including convective water vapor ablation (Rezum) and prostatic urethral lift (UroLift). While these treatments can be performed outside of the operating room, they do require special equipment and the use of rigid cystoscopy. A new class of treatments, which utilize no special equipment beyond a flexible cystoscope, is emerging, the first of which, the temporary implantable nitinol device (iTind), is already FDA… More >

  • Open AccessOpen Access

    REVIEW

    The clinical applications of five-alpha reductase inhibitors

    Kevin R. Loughlin
    Canadian Journal of Urology, Vol.28, No.2, pp. 10584-10588, 2021
    Abstract Introduction: Five-alpha reductase (5-AR) deficiency was first identified by Imperato-McGinley and Walsh as the cause of pseudohermaphroditism in two separate studies. The discoveries led to the development of finasteride (inhibitor of type 2 isoenzyme of 5-AR) and dutasteride (inhibitor of type 1 and type 2 isoenzymes of 5-AR).
    Both drugs have been proven effective for the treatment of benign prostatic hyperplasia, improving voiding symptoms, reducing the risk of urinary retention, and decreasing the need for prostate surgery.
    Five-alpha reductase inhibitors (5-ARIs) have also been demonstrated to be chemopreventive agents, reducing the risk of prostate cancer, although the… More >

  • Open AccessOpen Access

    ARTICLE

    Male stress urinary incontinence is often underreported

    Avery R. Wolfe, Roger K. Khouri Jr., Raj R. Bhanvadia, Benjamin M. Dropkin, Gregory A. Joice, Sarah C. Sanders, Steven J. Hudak, Allen F. Morey
    Canadian Journal of Urology, Vol.28, No.2, pp. 10589-10594, 2021
    Abstract Introduction: Patient-reported pads per day use is a widely used metric in grading the severity of stress urinary incontinence and guiding surgical decision-making, particularly in mild-to-moderate cases. We sought to compare patient-reported stress urinary incontinence severity by pads per day with objective findings on standing cough test. We hypothesize that patient-reported pads per day often underestimates stress urinary incontinence severity.
    Materials and methods: We retrospectively reviewed our male stress urinary incontinence surgical database and identified 299 patients with self-reported mild-to-moderate stress urinary incontinence who were evaluated with standing cough test prior to surgical intervention between 2007 and… More >

  • Open AccessOpen Access

    COMMENTARY

    The importance of accurate and standardized incontinence assessment

    David E. Rapp, Hamza Beano
    Canadian Journal of Urology, Vol.28, No.2, pp. 10595-10595, 2021
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    ARTICLE

    Imaging urothelial bladder cancer: A VPAC PET targeted approach

    Mathew L. Thakur1,2,3,4, Sushil K. Tripathi1, Leonard G. Gomella3,4, Ebru Salmanoglu5, Sung Kim1, William K. Kelly4,6, Scott W. Keith7, Charles Intenzo1, Peter McCue8, Jean Hoffman-Censits9, Edouard J. Trabulsi3,4
    Canadian Journal of Urology, Vol.28, No.2, pp. 10596-10602, 2021
    Abstract Introduction: Accurate staging of urothelial bladder cancer (UBC) with imaging, which guides effective bladder cancer treatment, remains challenging. This investigation is to validate a hypothesis that targeting vasoactive intestinal and pituitary adenylate cyclase activating peptide (VPAC) receptors using 64Cu-TP3805 can PET image UBC efficiently.
    Materials and methods: Nineteen patients (aged 44-84 years) scheduled for radical cystectomy underwent VPAC positron emission tomography (PET) imaging prior to surgery. Sixteen had completed neoadjuvant chemotherapy before imaging. All 19 received 64Cu-TP3805 (148% ± 10% MBq) intravenously and were imaged 60 to 90 minutes later. Standard uptake value (SUV)max for malignant lesions and… More >

  • Open AccessOpen Access

    ARTICLE

    Relationship between operative duration and perioperative outcomes after radical cystectomy

    Kassem S. Faraj1, Nathanael Judge1, Gail Blodgett2, Mark D. Tyson II1
    Canadian Journal of Urology, Vol.28, No.2, pp. 10603-10609, 2021
    Abstract Introduction: Prolonged operative times have been associated with an increased risk of complications in other major abdominal surgeries. This study tests the hypothesis that longer operative times will be associated with an increased risk of perioperative complications after radical cystectomy (RC).
    Materials and methods: Adult patients who underwent RC from January 1, 2012, through December 31, 2016, were identified from the National Surgical Quality Improvement Program (NSQIP) database. A natural log transformation was used to determine cutoff points for operative times at the 33rd, 67th, and 90th percentiles: 272, 371, and 479 minutes, respectively. Cohorts were divided… More >

  • Open AccessOpen Access

    ARTICLE

    Focal bladder neck cautery associated with low rate of post-Aquablation bleeding

    Dean S. Elterman1, Susan Foller2, Burkhard Ubrig3, Alexander Kugler4, Vincent Misrai5, Angelo Porreca6, Dominik Abt7, Kevin C. Zorn8, Naeem Bhojani8, Lewis Kriteman9, Rahul Mehan10, Michael McDonald11, Steven A. Kaplan12
    Canadian Journal of Urology, Vol.28, No.2, pp. 10610-10613, 2021
    Abstract Introduction: To determine if focal bladder neck cautery is effective in reducing bleeding following prostate tissue resection for benign prostatic hyperplasia using Aquablation.
    Materials and methods: Consecutive patients from 11 countries in Asia, Europe, and North America who underwent Aquablation for symptomatic benign prostatic hyperplasia between late 2019 and January 2021 were included in the analysis. All patients received post-Aquablation non-resective focal cautery at the bladder neck.
    Results: A total of 2,089 consecutive Aquablation procedures were included. Mean prostate size was 87 cc (range 20 cc to 363 cc). Postoperative bleeding requiring transfusion occurred in 17 cases (0.8%, More >

  • Open AccessOpen Access

    ARTICLE

    Urologic emergencies before and after COVID-19: a retrospective chart review

    Zoe S. Gan, Cheyenne Williams, Olivia O. Familusi, Ayah El-Fahmawi, Rayan Kabaha, Daniel J. Lee, David I. Lee
    Canadian Journal of Urology, Vol.28, No.2, pp. 10614-10619, 2021
    Abstract Introduction: During the coronavirus disease 2019 (COVID-19) pandemic, decreased presentations for various emergent conditions have been observed. Our objective was to compare the volume of patients with urologic emergencies presenting to emergency departments (EDs) within a single health system before and after the onset of the COVID-19 pandemic. Materials and methods: A retrospective chart review was performed for 3 EDs within a single health system in the United States to identify all ED consults to urology from January 1, 2019 to May 31, 2020. For emergent consults, covariates were extracted, including demographic information, insurance status,… More >

  • Open AccessOpen Access

    ARTICLE

    Pathological characteristics of the large renal mass: potential implication for clinical role of renal biopsy

    Aeen M. Asghar1, Andrew G. McIntosh1, Zachary L. Smith2, Neil J. Kocher3, Ziho Lee1, Nimrod N. Barashi2, Tianyu Li1, Jay D. Raman3, Scott E. Eggener2, Robert G. Uzzo1, Alexander Kutikov1
    Canadian Journal of Urology, Vol.28, No.2, pp. 10620-10624, 2021
    Abstract Introduction: To assess whether patients with a large renal mass, treated by radical nephrectomy (RN), could have benefited from preoperative renal mass biopsy (RMB). The decision to perform partial nephrectomy (PN) for an organ-confined > 4 cm renal mass can be complex. Although often feasible, the oncologic safety of PN in this cohort is debated. Yet, a significant portion of large renal masses that undergo RN prove benign or indolent, indicating a potential role for RMB to guide nephron preservation.
    Materials and methods: We queried prospectively maintained databases from three institutions to identify patients who underwent RN… More >

  • Open AccessOpen Access

    ARTICLE

    Virtue male sling outcomes and application to a contemporary nomogram

    David Abramowitz1, Andre-Philippe Sam2, Mark Pachorek3, Jim Shen1, Nora Ruel4, Jonathan N. Warner1
    Canadian Journal of Urology, Vol.28, No.2, pp. 10625-10630, 2021
    Abstract Introduction: To report outcomes of our Virtue male sling series and evaluate predictors of surgical success and failure. We also retrofit the Male Stress Incontinence Grading Scale (MSIGS) refined nomogram, including the standing cough test (SCT), to assess its application to our cohort.
    Materials and methods: A retrospective review was completed at a single institution over a 4-year period of all Virtue male slings implanted for stress urinary incontinence (SUI). Patient demographics including pad usage per day (PPD) and MSIGS were obtained on all patients after their bladders were filled cystoscopically. Failure was defined as >1 PPD… More >

  • Open AccessOpen Access

    COMMENTARY

    Virtue male sling – Is it really an adjustable sling?

    Jack M. Zuckerman
    Canadian Journal of Urology, Vol.28, No.2, pp. 10631-10631, 2021
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    ARTICLE

    Family history in patients who would have been candidates for active surveillance

    Mohammed Shahait1,3, Daniel Lee1,2, Jessica L. Kim1, Suzy Na1, David I. Lee1
    Canadian Journal of Urology, Vol.28, No.2, pp. 10632-10637, 2021
    Abstract Introduction: It is unknown whether a family history of prostate cancer confers additional risk among men who are candidates for active surveillance (AS).
    Materials and methods: Using a prospectively maintained database of men who underwent radical prostatectomy (RP) (2010-2018), candidates for AS were identified according to the expanded criteria. Pathological upgrading was defined as a pathologic Gleason score (pGS) of 3+4 or higher for patients with a biopsy GS of 3+3 and a pGS of 4+3 or higher for patients with a biopsy GS of 3+4. Major upgrading was defined as a pGS of 4+4 or higher.… More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Transurethral resection of prostatic abscess

    Mark G. Biebel1, Wesley R. Pate1, Toby C. Chai1
    Canadian Journal of Urology, Vol.28, No.2, pp. 10638-10642, 2021
    Abstract Prostateabscess(PA)isanuncommonprostaticinfection, with risk factors including indwelling catheters, acute or chronic prostatitis, bladder outlet obstruction, voiding dysfunction, recent urologic instrumentation (especially transrectalprostatebiopsy),chronickidneydisease(CKD), diabetes mellitus (DM), human immunodefciency virus (HIV), intravenous drug use (IVDU), and hepatitis C. Treatment of PA consists of antibiotics and abscess drainage via transurethral resection (TUR) or image-guided transrectal or transperineal drainage. Numerous studies have demonstrated that TUR of PA has a higher success rate and shorter hospital length of stay when compared to image-guided drainage. Despite this, TUR of PA is a relatively uncommon surgery with few useful recommendations on how to… More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Oncogene targeted therapy for metastatic primary scrotal melanoma

    Blair Stocks1, Hunter Fuentes1, Zachary McDowell1, Michael Brooks1,2, Jeffrey A. Jones1,2
    Canadian Journal of Urology, Vol.28, No.2, pp. 10643-10647, 2021
    Abstract Primary scrotal melanoma represents the rarest genitourinary malignancy. We describe the 25th reported case. The 79-year-old patient presented with a rapidly enlarging right cutaneous scrotal mass which after local excision demonstrated pT4b nodular malignant melanoma (BRAF V600E mutation positive). The patient underwent wide local excision of his hemiscrotum and inguinal lymph node dissection demonstrating nodes positive for melanoma (pN2b). Postoperatively, the patient developed a left sided malignant pleural effusion (M1b). Per American Joint Commission Cancer staging, BRAF mutant targeted therapy (dabrafenib) was initiated. This case documents the first instance in which metastatic scrotal melanoma will More >

  • Open AccessOpen Access

    HOW I DO IT

    How I Do It: The pudendal nerve block for pediatric ambulatory urologic surgery

    Blair Stocks1, Hunter Fuentes1, Zachary McDowell1, Michael Brooks1,2, Jeffrey A. Jones1,2
    Canadian Journal of Urology, Vol.28, No.2, pp. 10648-10651, 2021
    Abstract Regional analgesia is an important adjunct for perioperative pain management in the setting of pediatric penile surgeries. Caudal epidural analgesia (CEA) is the most common analgesic technique performed, but it has limitations and associated morbidity. The pudendal nerve block (PNB) is an effective alternative to CEA with a lower risk profile; in prior examination of the approach, PNB has been demonstrated to have similar postoperative pain control outcomes. We describe our technique and highlight observations made as we have transitioned from CEA to PNB for many patients. More >

Per Page:

Share Link