Open Access

EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.30, No.5, pp. 11644-11644, 2023
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BOOK REVIEW

Thomas J. Guzzo
Canadian Journal of Urology, Vol.30, No.5, pp. 11645-11645, 2023
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LEGENDS IN UROLOGY

Christopher Chapple
Canadian Journal of Urology, Vol.30, No.5, pp. 11646-11649, 2023
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ARTICLE

Kussil Oumedjbeur¹, Nicholas J. Corsi², David Bouhadana³, Ahmed Ibrahim⁴, David-Dan Nguyen⁵, Imad Matta⁴, Adel Arezki³, Iman Sadri³, Tawfik Elsherbini⁶, Naeem Bhojani⁴, Dean S. Elterman⁵, Bilal Chughtai⁷, Brian T. Helfand⁸, Alexander P. Glaser⁸, Vincent Misrai⁹, Steven Kaplan¹⁰, Peter Gilling¹¹, Neil Barber¹², Mihir Desai¹³, Gopal H. Badlani¹⁴, Alexis E. Te⁷, Claus G. Roehrborn¹⁵, Kevin C. Zorn⁴
Canadian Journal of Urology, Vol.30, No.5, pp. 11650-11658, 2023
Abstract Introduction: To report the 5-year efficacy and safety of Aquablation compared with transurethral resection of the prostate for the management of lower urinary tract symptoms secondary to benign prostatic hyperplasia in men with prostate volumes 50-80 mL.
Materials and methods: In a large double-blinded, multicenter, and prospective randomized controlled trial, 96 randomized men with 50-80 mL prostates who underwent Aquablation or transurethral prostate resection were prospectively identified for subgroup analysis. Follow up was performed for up to 5 years. The primary efficacy endpoint was the reduction in International Prostate Symptom Score (IPSS) at 6 months. The primary… More >

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ARTICLE

Logan G. Briggs^1,*, Nishant Uppal^2,*, Björn Langbein³, Naeem Bhojani⁴, Martin Kathrins³, Quoc-Dien Trinh³
Canadian Journal of Urology, Vol.30, No.5, pp. 11659-11667, 2023
Abstract Introduction: To characterize venture capital (VC) investments in urology in the past decade that represent promising innovations in early-stage companies.
Materials and methods: A retrospective analysis of deals made between VC investors and urologic companies from January 1, 2011, through June 28, 2021, was conducted by using a financial database (PitchBook Platform, PitchBook Data Inc). Data on urologic company and investor names; company information and funding categories (surgical device, therapeutic device, drug discovery/pharmaceutical, and health care technology companies); and deal sizes (in US dollars) and dates were abstracted and aggregated. Descriptive and linear regression analyses were conducted.
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EDITORIAL COMMENT

Leonard G. Gomella
Canadian Journal of Urology, Vol.30, No.5, pp. 11667-11667, 2023
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ARTICLE

Tobias S. Kohler¹, Sankar J. Kausik²
Canadian Journal of Urology, Vol.30, No.5, pp. 11668-11675, 2023
Abstract Introduction: This study compares subjective lower urinary tract symptoms (LUTS) to objective voiding parameters measured during the UroCuff Test, a non-invasive pressure flow study (PFS), in men presenting with LUTS attributed to benign prostatic hyperplasia (BPH).
Materials and methods: This is an expanded subpopulation analysis of a previously reported group of 50,680 men with LUTS, which depicted increased disease progression as men age. During the UroCuff Test, investigators optionally provided the International Prostate Symptom Score (IPSS). Variables were analyzed using descriptive statistics, pairwise correlation coefficients between variables and a multivariable linear regression model fit for IPSS as… More >

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ARTICLE

Kenneth M. Kernen¹, Shalina Omar², Bradley Goodnight², Paul Skodny³, Stuart Bruce³, Tiffany M. Yu²
Canadian Journal of Urology, Vol.30, No.5, pp. 11676-11685, 2023
Abstract Introduction: To evaluate the safety and efficacy of the temporarily implanted nitinol device (iTind) versus prostatic urethral lift (PUL) for minimally invasive surgical treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia in a matching-adjusted indirect comparison (MAIC).
Materials and methods: Seven clinical trials were identified via a systematic literature review. Individual patient data from iTind trials and aggregated data from PUL trials were used in the MAIC. Safety and efficacy outcomes at 12 months post-treatment were compared between the adjusted iTind population and the pooled PUL population.
Results: iTind patients were significantly less likely than… More >

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ARTICLE

Arjun Pon Avudaiappan¹, Pushan Prabhakar¹, Hariharan Ganapathi², Nathan VanderVeer-Harris³, Jorge Caso^1,3, Rohan Garje¹, Murugesan Manoharan^1,3
Canadian Journal of Urology, Vol.30, No.5, pp. 11686-11691, 2023
Abstract Introduction: Radical cystectomy (RC) is an effective curative treatment option for muscle-invasive bladder cancer (MIBC). However, chemoradiation (CRT) is an evolving bladder preservation protocol alternative to RC. With the increase in life expectancy, it is essential to understand the survival outcomes among octogenarians treated with RC and CRT. In this study, we use the National Cancer Database (NCDB) to compare the survival outcomes between RC and CRT in octogenarians.
Materials and methods: We collected the data of patients treated for bladder cancer between 2004 to 2018 from the NCDB. Our primary analytic cohort included patients with MIBC… More >

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ARTICLE

Christopher J. Staniorski¹, Mitchell B. Alameddine¹, Shyam Patnaik¹, Michelle J. Semins²
Canadian Journal of Urology, Vol.30, No.5, pp. 11692-11697, 2023
Abstract Introduction: Proper antegrade access for percutaneous nephrolithotomy (PCNL) is essential for success but can be challenging. Previous work evaluating access obtained by interventional radiology (IR), largely in the emergent setting, has shown high rates of additional access at the time of PCNL. We hypothesize that efforts to improve pre-procedural communication between urology and IR can impact the utility of the access for subsequent PCNL.
Material and methods: We conducted a retrospective review of patients undergoing PCNL at a single hospital from January 2011 to December 2022. Adult patients undergoing PCNL with established preoperative access were included.
Results: A… More >

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ARTICLE

Lauren S. Faber, Tania Lyons, Michael S. Davis
Canadian Journal of Urology, Vol.30, No.5, pp. 11698-11702, 2023
Abstract Introduction: The United Network for Organ Sharing (UNOS) is tasked with ensuring fair and equitable access to organs for patients seeking transplant. Despite UNOS’ position statement clearly stating that prisoner status should not preclude transplant evaluation, prisoners continue to face significant barriers. The goal of this survey was to discover how many American transplant centers are willing to evaluate, list, and transplant prisoners.
Materials and methods: All adult kidney transplant centers listed as active on the UNOS website were contacted to participate in a survey asking if they were willing to evaluate, list, and transplant prisoners, and… More >

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ARTICLE

Stephanie Jensen^*, Akin S. Amasyali^*, Mohamed Keheila, Ashley Feldkamp, Jonathan Maldonado, Hillary J. Wagner, D. Duane Baldwin, Andrea Staack
Canadian Journal of Urology, Vol.30, No.5, pp. 11703-11707, 2023
Abstract Introduction: Liposomal bupivacaine (LB) is a depot formulation of bupivacaine, which releases the drug over 72 hours to prolong local pain control. This retrospective study compares the effect of using LB versus plain bupivacaine on postoperative pain control, length of hospital stay and cost among patients undergoing vaginal reconstructive surgery.
Materials and methods: Patients who underwent vaginal reconstructive surgery with levatorplasty and received an injection of 20 cc of either plain bupivacaine or LB for pudendal nerve block were included. The primary outcomes included postoperative narcotic use and subjective pain score. The secondary outcome was postoperative length… More >

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