Open Access

EDITORIAL

Timothy D. Averch
Canadian Journal of Urology, Vol.20, No.3, pp. 6743-6743, 2013
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LEGENDS IN UROLOGY

George D. Webster
Canadian Journal of Urology, Vol.20, No.3, pp. 6744-6747, 2013
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REVIEW

Bradley C. Carthon^1,2, David M. Marcus^2,3, Lindsey A. Herrel⁴, Ashesh B. Jani^2,3,4, Peter J. Rossi^2,3,4, Daniel J. Canter^2,4
Canadian Journal of Urology, Vol.20, No.3, pp. 6748-6755, 2013
Abstract Introduction: Radical prostatectomy is an effective primary treatment for clinically localized prostate cancer. While many patients are cured of their disease after surgery, there are still a significant proportion of men who will develop a biochemical recurrence (BCR). In this review, we detail existing treatment algorithms for this group of patients as well as future therapies that show great promise.
Materials and methods: A review of the literature was performed, and relevant, high-impact articles were identified and reviewed focusing on the treatment of men with BCR after surgery for prostate cancer. Wherever possible, we used data from… More >

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COMMENTARY

Leonard G. Gomella
Canadian Journal of Urology, Vol.20, No.3, pp. 6755-6755, 2013
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ARTICLE

Xiaoye Zhu, Ries Kranse, Meelan Bul, Chris H. Bangma, Fritz H. Schröder, Monique J. Roobol
Canadian Journal of Urology, Vol.20, No.3, pp. 6756-6760, 2013
Abstract Introduction: To assess the extent of overestimation of the cumulative probability of death by the Kaplan-Meier method with the competing-risks regression analysis as reference approach.
Materials and methods: Data were derived from the screening arm of the Rotterdam branch of the European Randomized Study of Screening for Prostate Cancer (ERSPC). The screening arm consisted of 21210 men between the ages of 55 and 74 at study entry. Follow up concerning mortality was complete through 2008. Endpoints were 5 and 10 year cumulative probabilities of prostate cancer death and death from other causes. Relative bias was defined as… More >

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ARTICLE

Orkunt Özkaptan, Tahir Karadeniz, Vahit Guzelburc, Kayhan Yilmaz, Oğuz Yilanoğlu, Süleyman Sahin
Canadian Journal of Urology, Vol.20, No.3, pp. 6761-6767, 2013
Abstract Introduction: To determine the effects of pelvic dimensions on margin status, preoperative and postoperative estimated blood loss (EBL), operative time and transfusion rate (TR) during radical retropubic prostatectomy (RRP).
Materials and methods: Data from 94 patients with preoperative prostate MRI were analyzed. Pelvic dimensions, including interspinous distance (ISD), bony (BFW) and soft tissue (SW) pelvic width, apical prostate depth (AD), upper conjugate (UC), lower conjugate (LC) were measured by preoperative MRI. Indexes for pelvic dimensions (PDI), bony width (BWI) and soft-tissue width (SWI) were defined as ISD/AD, BFW/PD, and SW/AD, respectively. As indicators of surgical difficulty, TR… More >

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ARTICLE

Jack M. Zuckerman, Katherine Henderson, Kurt McCammon
Canadian Journal of Urology, Vol.20, No.3, pp. 6768-6772, 2013
Abstract Introduction: A potential learning curve associated with AdVance (American Medical Systems, Minnetonka, MN, USA) sling placement has not been adequately reported.
Materials and methods: Retrospective analysis of our AdVance single surgeon database. Patients with a history of a radical prostatectomy, no past radiation or prior incontinence interventions and at least 12 months of follow up were included. A learning curve was evaluated by predicting patient outcomes using their order within the surgical log. Univariate and multivariate logistic regressions were performed.
Results: Sixty patients with mean age of 65 years and an average 28.2 months of follow up were More >

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ARTICLE

Paul J. Smith, Steven J. Hudak, J. Francis Scott, Lee C. Zhao, Allen F. Morey
Canadian Journal of Urology, Vol.20, No.3, pp. 6773-6777, 2013
Abstract Introduction: To explore the association of artificial urinary sphincter (AUS) cuff sizes and placement techniques with the development of postoperative urinary retention.
Materials and methods: We analyzed the outcomes of AUS cases performed by a single surgeon at a tertiary referral center from 2007 to 2010. Outcomes relating to urinary retention and suprapubic tube placement were analyzed in three groups: those with 3.5 cm cuff placement, ≥ 4 cm cuff placement, and transcorporal cuff (TC) placement of any size.
Results: Among 139 patients who underwent AUS placement from 2007 to 2010, 117 cases met inclusion criteria – 42 More >

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ARTICLE

Steven N. Sterious¹, Jay Simhan¹, Marc C. Smaldone¹, Kevin J. Tsai¹, Daniel Canter², Edward Wameedh³, Tianyu Li⁴, James Helstrom⁵, Rosalia Viterbo¹, David Y. T. Chen¹, Richard E. Greenberg¹, Alexander Kutikov¹, Tahseen Al-Saleem³, Robert G. Uzzo
Canadian Journal of Urology, Vol.20, No.3, pp. 6778-6784, 2013
Abstract Introduction: The utility of frozen section performance during partial nephrectomy (PN) is controversial. We assessed the predictive value of frozen sections on final margin status for patients undergoing PN for localized renal tumors.
Materials and methods: We queried our prospectively maintained kidney cancer database for patients undergoing PN with localized renal tumors from 2005 to 2011. Patients were stratified based on the receipt of frozen section analysis into ‘frozen’ and ‘no frozen’ groups. Groups were compared using ANOVA, Chi-square, and Wilcoxon’s tests.
Results: A total of 537 patients (mean age 58.1 years ± 12.0 years, 64.2% male) underwent… More >

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ARTICLE

Stephen Faddegon, Tom Ju, Ephrem O. Olweny, Zhuowei Liu, Woong K. Han, Gang Yin, Yung K. Tan, Jeffrey Gahan, Selahattin Bedir, Yun-Bo Ma, Samuel K. Park, Ganesh V. Raj, Jeffrey A. Cadeddu
Canadian Journal of Urology, Vol.20, No.3, pp. 6785-6789, 2013
Abstract Introduction: To compare long term glomerular filtration rate (GFR) outcomes of partial nephrectomy and radiofrequency ablation performed for renal malignancy.
Materials and methods: Renal function of 347 patients undergoing radiofrequency ablation (n = 142) or partial nephrectomy (n = 205) for renal malignancy between 1994 and 2011 were compared from a retrospective database at a single tertiary care center. Minimum 1 year of follow up was required, resulting in a mean follow up of 48.2 (SD +/- 28.2) months. Renal function was estimated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. The primary study outcome was More >

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ARTICLE

Ryan P. Kopp^1,2, Lejla Aganovic^3,4, Kerrin L. Palazzi¹, Fiona H. Cassidy^3,4, Kyoko Sakamoto^1,2, Ithaar H. Derweesh^1,2
Canadian Journal of Urology, Vol.20, No.3, pp. 6790-6797, 2013
Abstract Introduction: To further elucidate potential patterns of contrast enhancement for renal neoplasm subtypes, we investigated the utility of a contrast washout formula to differentiate renal tumor histology after multiphase computerized tomography (CT).
Materials and methods: A single-center retrospective cohort study of 163 patients with multiphase CT for renal masses obtained from October 2007 to July 2012. Pathology confirmed clear cell renal cell carcinoma (CC-RCC; n = 92), papillary (Pa-RCC; n = 43), chromophobe (Ch-RCC; n = 6), oncocytoma (OC; n = 11), or angiomyolipoma (AML; n = 11) histology. Two radiologists in consensus, blinded to histology, recorded… More >

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COMMENTARY

Daniel J. Canter
Canadian Journal of Urology, Vol.20, No.3, pp. 6798-6798, 2013
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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Federica Scavonetto¹, David R. Lamborn¹, Joan M. Mccaffrey¹, Darrell R. Schroeder², Mattew T. Gettman³, Juraj Sprung¹, Toby N. Weingarten¹
Canadian Journal of Urology, Vol.20, No.3, pp. 6799-6804, 2013
Abstract Introduction: Two prospective trials have demonstrated that prophylactic antimuscarinics following prostatectomy reduce pain from bladder spasms. Our practice adopted the routine administration of prophylactic belladonna and opium (B&O) suppositories to patients undergoing robotic-assisted laparoscopic radical prostatectomy (RALP). The aim of this study is to determine if this change in clinical practice was associated with improvement of postoperative outcomes.
Materials and methods: The medical records of 202 patients who underwent RALP surgery, either administered or not administered prophylactic B&O suppositories in the immediate postoperative period, were abstracted for duration of anesthesia recovery, pain, and analgesic use.
Results: Patient and… More >

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RESIDENT’S CORNER

Leslie Nicolay, Jordan Gitlin, Lane S. Palmer
Canadian Journal of Urology, Vol.20, No.3, pp. 6805-6807, 2013
Abstract We present the first case of torsion of an appendix testis in a cryptorchid testicle. The difficulties in history, physical examination and imaging posed by such a presentation are presented as well as management considerations. More >

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RESIDENT’S CORNER

Vladimir Ruzhynsky, Paul Whelan
Canadian Journal of Urology, Vol.20, No.3, pp. 6808-6810, 2013
Abstract Gonadotropin releasing hormone (GnRH) antagonists, such as degarelix, are emerging as an androgen deprivation therapy primary agents in a treatment of advanced prostate cancer. The role of GnRH antagonists in management of lower urinary tract symptoms associated with prostate cancer has not been clearly established. In this report, we describe the case of a patient with locally advanced prostate cancer who presented with symptoms of urinary retention and renal failure. The use of degarelix in this patient led to a rapid reduction in the prostate-specific antigen level; however, obstructive symptoms persisted despite the use of More >

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RESIDENT’S CORNER

Christopher E. Bayne¹, William A. Davis², Christopher P. Rothstein³, Jason D. Engel¹
Canadian Journal of Urology, Vol.20, No.3, pp. 6811-6814, 2013
Abstract Transrectal ultrasound guided biopsy (TRUSB) of the prostate directly contaminates the prostate with rectal flora. Patients commonly receive fluoroquinolone (FQ) antibiotics to prevent infection. Infectious complications following TRUSB are increasing. The most common offending organism is Escherichia coli (E. coli), with isolates of this bacteria showing growing resistance to FQs. We present to our knowledge the first reported case of seminal vesicle abscess formation after TRUSB. The abscess was initially not seen on computed tomography and eventually treated with percutaneous drainage by a transgluteal approach. We review literature on infectious complications following TRUSB with implications More >

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COMMENTARY

Jay D. Raman
Canadian Journal of Urology, Vol.20, No.3, pp. 6815-6815, 2013
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