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Camille Vuichoud, Kevin R. Loughlin
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 1-6, 2015
Abstract Introduction: Benign prostatic hyperplasia (BPH) is arguably the most common benign disease of mankind. As men age, the prostate inexorably grows often causing troubling symptoms causing them to seek out care. While traditionally treated by transurethral resection or open surgical removal of the hypertrophied adenoma, today the urologist has numerous medical, surgical and minimally invasive techniques available. In this supplement The Canadian Journal of Urology provides a review of the various techniques and medications available today.
Materials and methods: As an introduction to the supplement, the aim of this article is to review the epidemiology and economy… More >

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Brandon Van Asseldonk, Jack Barkin, Dean S. Elterman
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 7-17, 2015
Abstract instruction: Introduction: Benign prostatic hyperplasia (BPH) is a common disease that affects men as they age. Historically the treatment has been primarily surgical in nature, but over the past 25 years significant advances in medical therapy have been made, sparing some men from interventional procedures.
instruction: Materials and methods: This article highlights the current state-of-the-art with respect to medical therapy for lower urinary tract symptoms secondary to BPH (BPH-LUTS) including a review of landmark studies and recent areas of research in the field.
instruction: Results: Alpha blockers are considered first line when treating BPH-LUTS in men with… More >

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Aryeh Keehn, Franklin C. Lowe
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 18-23, 2015
Abstract instruction: Introduction: The use of complementary and alternative medications has become a multi-million dollar business in the United States and comprises more than half of all filled prescriptions for benign prostatic hyperplasia (BPH) in Europe. For the practicing urologist, understanding the phytotherapeutic agents available, their proposed mechanism of action, the research supporting their use, and their safety profiles has become increasingly important as more patients inquire into their use.
instruction: Materials and methods: A comprehensive literature search was conducted to identify pertinent articles pertaining to alternative and complementary treatment options for the management of BPH. Treatments demonstrating… More >

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Benjamin L. Taylor, William I. Jaffe
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 24-29, 2015
Abstract instruction: Introduction: We summarize the current guidelines, techniques, efficacy and complications associated with monopolar transurethral resection of the prostate (TURP) and transurethral incision of the prostate (TUIP) for benign prostatic hyperplasia (BPH). Patients who elect to have endoscopic surgical bladder outlet reduction are faced with an abundance of evolving treatment options. As new technology comes and goes, TURP and TUIP remain the gold standard for which new treatments are compared.
instruction: Materials and methods: A review of past and contemporary data including American and European guidelines was performed. Techniques, efficacy, durability, short term and long term complications… More >

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Rodrigo Donalisio da Silva^1,*, Luke Bidikov^1,2,*, Walker Michaels¹, Diedra Gustafson¹, Wilson R. Molina^1,2, Fernando J. Kim^1,2
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 30-44, 2015
Abstract instruction: Introduction: For decades, the monopolar transurethral resection of the prostate has been established as the minimally invasive surgical treatment for patients with benign prostatic hyperplasia (BPH). In recent years, new technologies and devices emerged to reduce the morbidity and improve outcomes for this treatment approach. Bipolar energy introduced the use of saline irrigation and laser technology increased the urological armamentarium to treat BPH. We performed a systematic review of the literature regarding bipolar technology for the treatment of BPH.
instruction: Materials and methods: A MEDLINE database search using the PRISMA methodology. Selected literature was restricted to… More >

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Côme Tholomier, Roger Valdivieso, Pierre-Alain Hueber, Kevin C. Zorn
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 45-52, 2015
Abstract instruction: Introduction: Transurethral resection of the prostate (TURP) is still considered the gold standard to treat benign prostatic hyperplasia (BPH). However, photoselective vaporization of the prostate (PVP) has gained widespread acceptance as an alternative option requiring preoperative patient selection. Four laser systems are currently in use: holmium, thulium, diode and GreenLight.
instruction: Materials and methods: The goal of this article is to review the physics and the basics behind laser prostatectomies, as well as to present the most current literature concerning the results, advantages, disadvantages and international recommendations for each vaporization procedure.
instruction: Results: Holmium laser ablation of… More >

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Lori B. Lerner, Archana Rajender
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 53-59, 2015
Abstract instruction: Introduction: Laser treatment of benign prostatic hyperplasia (BPH) through enucleation techniques has become increasingly more utilized in the field of urology. Laser enucleation of the prostate (LEP) is a transurethral procedure that employs several different types of lasers to dissect the adenoma from the surgical capsule in a retrograde fashion.
instruction: Materials and methods: We review basic laser physics and current laser prostate enucleation techniques. Holmium-LEP (HoLEP), Thulium-LEP (ThuLEP), Greenlight-LEP (GreenLEP) and Diode-LEP (DiLEP) applications are discussed. We summarize the current literature with respect to functional outcomes and complications.
instruction: Results: Although each laser device used for… More >

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Mark Ferretti, John Phillips
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 60-66, 2015
Abstract instruction: Introduction: Prostatectomy for benign disease, also known as a 'simple prostatectomy', is neither simple in indication nor approach. In the post-Medical Therapy of Prostatic Symptoms (MTOPS), NCT00021814 trial era, the medical management of benign prostatic hyperplasia (BPH) and consequent bladder outlet obstruction (BOO) has shifted surgical intervention to those patients who are medical-non responders, present with advanced signs of BOO and obstructive uropathy, and those with prostate gland volumes beyond the size normally approachable with standard transurethral resection of the prostate (TURP). Simple prostatectomy through an open surgical approach is associated with improvements in BOO… More >

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Daniel B. Rukstalis
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 67-74, 2015
Abstract instruction: Introduction: Benign prostatic hyperplasia (BPH) is an obligate disorder of the aging male prostate with close associations to other metabolic conditions of aging including obesity. Clinical manifestations of this chronic disorder increase as men age suggesting that a growing number of older men will require intervention for progressive voiding symptoms or bladder dysfunction.
instruction: Materials and methods: The Prostatic Urethral Lift (PUL) procedure represents a new endoscopic approach in which small permanent intraprostatic implants are positioned to correct bladder outlet obstruction without tissue destruction. An overview of the treatment modality, review of recent literature, and analysis… More >

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Charles C. Peyton, Gopal H. Badlani
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 75-81, 2015
Abstract instruction: Introduction: Elderly men with multiple comorbidities may be unfit to undergo surgical management of benign prostatic obstruction (BPO). Permanent and temporary prostatic stents have been developed as an alternative to chronic indwelling catheters in men unfit for surgery.
instruction: Materials and methods: Herein we review the past and present literature on the role and effectiveness of prostatic stents in the treatment of BPO.
instruction: Results: Permanent prostatic stents have largely been abandoned in North America due to unfavorable outcomes and improved technologies to allow for treatment of BPO. Currently, the temporary Spanner stent is the only available More >

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Shiva Madhwan Nair, Marie Adrianne Pimentel, Peter J. Gilling
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 82-87, 2015
Abstract instruction: Introduction: Lower urinary tract symptoms (LUTS) are common and are often caused by benign prostatic hyperplasia (BPH). Traditional surgical methods of open enucleation and transurethral resection of prostate (TURP) have been efficacious in alleviating these symptoms however, these are operator dependent and often come with significant side effects. In this review, we will discuss upcoming new surgical techniques in management of BPH.
instruction: Materials and methods: A systematic search of SCOPUS, MEDLINE, EMBASE and Cochrane databases were carried out using relevant key words.
instruction: Results: Intra-prostatic injections with a variety of agents have been explored as these… More >

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Daniel C. Parker¹, Jay Simhan^1,2
Canadian Journal of Urology, Vol.22, Suppl.5, pp. 88-92, 2015
Abstract instruction: Introduction: Lower urinary tract symptoms are a common complaint. Surgery to debulk hyperplastic prostate tissue is indicated for men with symptoms refractory to medical therapy, or for those who cannot tolerate first-line medications. In recent decades, new endoscopic techniques have been developed to reduce the morbidity of transurethral resection of the prostate (TURP). Nonetheless, complications are still frequently encountered in the immediate, early, and remote postoperative setting.
instruction: Materials and methods: In this review, we perform an in-depth examination of contemporary treatment strategies for long term complications of surgical outlet reduction procedures. Complications encountered in the… More >

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