Impact of active surveillance on pathology and nerve sparing status
Rachael Sussman1, Ilene Staff2, Joseph Tortora2,
Alison Champagne2, Anoop Meraney2, Stuart S. Kesler3,
Joseph R. Wagner3
Canadian Journal of Urology, Vol.21, No.3, pp. 7299-7304, 2014
Abstract Introduction: We assessed whether, in comparison to immediate surgery, a time delay in performing radical prostatectomy (RP) in patients electing to undergo a period of active surveillance (AS) of low grade prostate cancer, is associated with adverse pathologic features, biochemical recurrence and the ability to perform effective nerve sparing surgery.
Materials and methods: From our RP database of 2769 patients, we identified 41 men under AS who subsequently underwent RP. This study group was compared to control group A (164 patients who chose RP rather than AS), matched for prostate-specific antigen (PSA) and initial diagnostic biopsy characteristics.… More >