Open Access

EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.21, No.3, pp. 7255-7255, 2014
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LEGENDS IN UROLOGY

Isabell Sesterhenn
Canadian Journal of Urology, Vol.21, No.3, pp. 7256-7258, 2014
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ARTICLE

Mark D. Tyson II¹, Alan H. Bryce², Thai H. Ho², Estrella M. Carballido², Erik P. Castle¹
Canadian Journal of Urology, Vol.21, No.3, pp. 7259-7265, 2014
Abstract Introduction: Few data on the perioperative outcomes of cystectomy after neoadjuvant chemotherapy (NAC) exist. In this study, we evaluated whether patients who had previously received NAC were at higher risk of developing perioperative complications.
Materials and methods: The National Surgical Quality Improvement Program (NSQIP) database was searched to identify cystectomies performed between January 1, 2005 and December 31, 2011. Of 1394 patients identified, about one-tenth (n = 122 [8.8%]) received NAC. A propensity-weighted comparative analysis of perioperative morbidity was conducted.
Results: In unadjusted comparisons, patients undergoing cystectomy after NAC were more likely to have peripheral nerve deficits (1.6%… More >

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ARTICLE

Casey Kowalik, Jason R. Gee, Andrea Sorcini, Alireza Moinzadeh, David Canes
Canadian Journal of Urology, Vol.21, No.3, pp. 7266-7270, 2014
Abstract Introduction: A single perioperative dose of intravesical chemotherapy (IVC) following transurethral resection of bladder tumors (TURBT) for non-muscle invasive bladder cancer has demonstrated a reduction in tumor recurrence. In this study, we investigate the contemporary (2010) utilization of IVC following TURBT using a prospective national database.
Materials and methods: Using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database, we identified patients with bladder cancer using ICD-9 codes. From this group, patients undergoing TURBT based on Current Procedural Terminology (CPT) codes were analyzed. We then identified those patients who underwent TURBT and also received… More >

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ARTICLE

Wassim M. Bazzi¹, Sheila Z. Dejbakhsh^2,3, Melanie Bernstein¹, Paul Russo¹
Canadian Journal of Urology, Vol.21, No.3, pp. 7271-7276, 2014
Abstract Introduction: To explore further the association of baseline health and gender with small renal mass pathology as approximately 20% of those masses are benign and women are twice as likely as men to have benign pathology.
Materials and methods: We conducted retrospective chart reviews of patients with renal masses ≤ 4 cm who underwent partial and radical nephrectomy from 1998 to 2012. Multivariable logistic regression analysis was performed to determine demographic and clinicopathologic factors associated with malignant pathology.
Results: In our cohort of 1726 patients, compared to patients with benign pathology, those with malignant pathology included a higher… More >

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ARTICLE

Zubair Cheema, Mazen Alsinnawi, Rowan G. Casey, John Corr
Canadian Journal of Urology, Vol.21, No.3, pp. 7277-7282, 2014
Abstract Introduction: Different techniques are used in open partial nephrectomy (OPN) for localized renal cancer, with variable impact on renal function. Regional renal ischemia technique by using different clamps and without the need to occlude renal vessels is gaining popularity. In our study, we present the largest international series; and the first in the United Kingdom; describing OPN using soft bowel clamp. We study the impact of this regional ischemia innovative technique on renal function, postoperative complications and oncological outcomes.
Materials and methods: We retrospectively analyzed the first 100 OPN cases done between 2001 and 2011. All available… More >

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ARTICLE

Brian J. Linder¹, Akira Kawashima², David A. Woodrum², Matthew K. Tollefson¹, R. Jeffrey Karnes¹, Brian J. Davis³, Laureano J. Rangel⁴, Bernard F. King², Lance A. Mynderse¹
Canadian Journal of Urology, Vol.21, No.3, pp. 7283-7289, 2014
Abstract Introduction: To evaluate the ability of endorectal coil (e-coil) magnetic resonance imaging (MRI) to identify early prostatic fossa recurrence after radical prostatectomy.
Materials and methods: We identified 187 patients from 2005–2011 who underwent e-coil MRI with dynamic gadolinium-contrast enhancement followed by transrectal ultrasound (TRUS) guided prostatic fossa biopsy for possible local prostate cancer recurrence. For analysis, local recurrence was defined as a negative evaluation for distant metastatic disease with a positive prostatic fossa biopsy, decreased prostate-specific antigen (PSA) following salvage radiation therapy, or increased lesion size on serial imaging.
Results: Local recurrence was identified in 132 patients, with… More >

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ARTICLE

Yun-Sok Ha^1,2, Dong Il Kang³, Jeong Hyun Kim⁴, Jae Young Joung⁵, Jihyeong Yu⁶, Jaspreet S. Parihar¹, Amirali Hassanzadeh Salmasi¹, Shigeo Horie⁷, Wun-Jae Kim⁸, Isaac Yi Kim¹
Canadian Journal of Urology, Vol.21, No.3, pp. 7290-7297, 2014
Abstract Introduction: Positive surgical margin (PSM) has classically been associated with biochemical recurrence (BCR) following radical prostatectomy (RP) and immediate adjuvant radiotherapy has been advocated based on two large randomized prospective clinical studies. However, a significant percentage of patients with PSM never experience BCR. This study evaluated factors potentially affecting risk of BCR among the patients with PSM after robot-assisted radical prostatectomy (RARP).
Materials and methods: From a prospectively maintained database, 699 patients with localized prostate cancer who underwent a RARP without any adjuvant therapy were identified. Median follow up was 46.0 months. To determine the pathologic and… More >

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COMMENTARY

Leonard G. Gomella
Canadian Journal of Urology, Vol.21, No.3, pp. 7298-7298, 2014
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ARTICLE

Rachael Sussman¹, Ilene Staff², Joseph Tortora², Alison Champagne², Anoop Meraney², Stuart S. Kesler³, Joseph R. Wagner³
Canadian Journal of Urology, Vol.21, No.3, pp. 7299-7304, 2014
Abstract Introduction: We assessed whether, in comparison to immediate surgery, a time delay in performing radical prostatectomy (RP) in patients electing to undergo a period of active surveillance (AS) of low grade prostate cancer, is associated with adverse pathologic features, biochemical recurrence and the ability to perform effective nerve sparing surgery.
Materials and methods: From our RP database of 2769 patients, we identified 41 men under AS who subsequently underwent RP. This study group was compared to control group A (164 patients who chose RP rather than AS), matched for prostate-specific antigen (PSA) and initial diagnostic biopsy characteristics.… More >

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ARTICLE

Fernando J. Kim^1,2, Priya N. Werahera³, David E. Sehrt¹, Diedra Gustafson¹, Rodrigo D. Silva¹, Wilson R. Molina¹
Canadian Journal of Urology, Vol.21, No.3, pp. 7305-7311, 2014
Abstract Introduction: Our safety net hospital offers minimally invasive, traditional open and perineal radical prostatectomies, as well as radiation therapy and medical oncological services when appropriate. Historically, only few African American and Hispanic patients elected surgical procedures due to unknown reasons. Interestingly, after initiation of the prostate cryoablation program (Whole Gland) in 2003 at Denver Health Medical Center (DHMC) we noticed a trend towards cryotherapy in these specific patient populations for the treatment of localized prostate cancer. We analyzed the profile of ethnic minority men evaluated for localized prostate cancer and evaluated the associated factors in the… More >

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ARTICLE

Ashok Verma¹, Jennifer St. Onge², Kam Dhillon³, Anita Chorneyko³
Canadian Journal of Urology, Vol.21, No.3, pp. 7312-7321, 2014
Abstract Introduction: Prostate-specific antigen (PSA) and the digital rectal exam (DRE) have moderate sensitivity but low specificity for cancer diagnosis, potentially causing unnecessary treatment complications with prostate biopsy. Transrectal ultrasound (TRUS) to evaluate prostate size and calculate PSA density can improve the specificity of PSA in predicting cancer. We evaluated the sensitivity and specificity of different pre-biopsy tests to detect prostate cancer.
Materials and methods: Pre-biopsy data were collected from 521 men referred for biopsy from January–December 2011 and cancer aggressiveness data from 96 men who had radical prostatectomy. Model predictors included total PSA, DRE, the ratio of… More >

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ARTICLE

Husein AlEnezi¹, Ahmed M. Isa², Basim Abu-Rafea², Khaled Madbouly³, Saleh Binsaleh¹
Canadian Journal of Urology, Vol.21, No.3, pp. 7322-7325, 2014
Abstract Introduction: A decline in semen quality in men with increasing percentage of male factor abnormalities in infertile couples has been reported. The pattern of abnormalities differs from one part of the world to another, and it is probably multifactorial. Our objectives were to review the pattern of semen fluid abnormalities in Saudi male partners of infertile couples, to establish prevalence and help future identification of responsible etiologies and possible treatments.
Materials and methods: A retrospective study of semen analysis results of male partners of infertile couples examined in a dedicated infertility clinic, King Khalid University Hospital, Riyadh,… More >

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RESIDENT’S CORNER

Parth K. Modi¹, Amirali Hassanzadeh Salmasi¹, Mark A. Perlmutter²
Canadian Journal of Urology, Vol.21, No.3, pp. 7326-7329, 2014
Abstract We present a case of an 83-year-old woman with multiple sclerosis and chronic indwelling urethral catheter who was found to have a ureteral injury after inadvertent placement of a foley catheter into the proximal right ureter. Cystoscopy and retrograde ureteral stenting was attempted, but unsuccessful. The patient ultimately underwent successful antegrade ureteral stenting and nephrostomy placement. We review the limited literature on the topic of aberrant foley catheter placement into the ureter. More >

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