Open Access

EDITORIAL

Gabriel P. Haas
Canadian Journal of Urology, Vol.14, No.3, pp. 3534-3534, 2007
Abstract This article has no abstract. More >

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REVIEW

Kavitha Ramachandran¹, Mark S. Soloway^1,2, Rakesh Singal^1,3, Murugesan Manoharan^1,2
Canadian Journal of Urology, Vol.14, No.3, pp. 3535-3541, 2007
Abstract DNA methylation and histone modifications constitute the common epigenetic modifications in vertebrate genomes. The epigenetic changes are early event in the cancer development and are reversible. Over the last decade, the field of epigenetics has made considerable progress both in the diagnosis and treatment of variety of malignancies. Novel epigenetic markers are being studied, which have the potential as sensitive diagnostic and prognostic markers. DNA methylation has been identified as a powerful diagnostic tool in classification, detection and risk assessment of cancers. As DNA methylation is reversible, inhibitors of DNA methyl transferases and histone deacteylases More >

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ARTICLE

Winson Y. Cheung¹, Alain Demers², Deloar Hossain³, Tim Owen⁴, Shahida Ahmed⁴, Piotr M. Czaykowski⁵
Canadian Journal of Urology, Vol.14, No.3, pp. 3542-3550, 2007
Abstract Objective: Testicular cancer is a highly curable malignancy of young men. Appropriate and timely management is critical to ensure optimal clinical outcomes. A 3-year population-based review of testicular cancer patients in Manitoba, Canada was undertaken to evaluate our management patterns.
Methods: Men diagnosed with testicular cancer from 1998 to 2000 were identified from the Provincial Cancer Registry. Chart review was utilized to collect information on demographic characteristics, timelines of diagnostic and staging investigations, completeness of pathology reports, management, and outcomes.
Results: Seventy-eight men were identified with 80 testicular cancers: 46 (59%) patients had 48 seminomas and 32… More >

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ARTICLE

John B. Malcolm¹, Ithaar H. Derweesh¹, Matthew C. Kincade¹, Christopher J. DiBlasio¹, Kimberly D. Lamar², Robert W. Wake¹, Anthony L. Patterson¹
Canadian Journal of Urology, Vol.14, No.3, pp. 3551-3559, 2007
Abstract Introduction: Androgen deprivation therapy (ADT) is widely utilized for treatment of localized and advanced prostate cancer (CaP). ADT is associated with increased rates of osteoporosis; however, its impact on fracture risk is not completely understood. We investigated incidence and predisposing factors for osteoporosis and fractures in a large, contemporary, single institution series of patients treated with ADT for CaP.
Methods: We retrospectively reviewed medical records of all patients who received ADT for CaP between 1/1989 and 7/2005. Primary endpoints of investigation were osteoporosis and non-pathologic fractures. Independent variables included age, race, body mass index (BMI), pretreatment… More >

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ARTICLE

Tony Y. H. Chen¹, Yves Ponsot¹, Martin Brouillette², Jean-Pierre Tétrault³, Le Mai Tu¹
Canadian Journal of Urology, Vol.14, No.3, pp. 3560-3565, 2007
Abstract Objectives: The study evaluates the effect of chronic usage, beyond the recommended maintenance schedule, on the efficacy of electromagnetic lithotripter. To our knowledge, there is no publication investigating the effect of chronic usage on the electromagnetic lithotripter, despite the maintenance schedule established by the manufacturers. Our goal is to verify if the acoustic parameters of the shock wave changed with usage, and if this change could be associated with change in clinical efficacy.
Methods: This study lasted 18 months. Every 6 months the lithotripter's efficacy was evaluated in two ways: objectively and clinically. Objective efficacy was… More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Ronald S. Boris, Sanjeev A. Kaul, Richard C. Sarle, Hans J. Stricker
Canadian Journal of Urology, Vol.14, No.3, pp. 3566-3570, 2007
Abstract Objective: To compare perioperative, functional and oncological outcomes of a single surgeon's experience with retropubic (RRP), perineal (RPP), and robotic assisted (RARP) radical prostatectomy.
Methods: Results from 150 radical prostatectomies performed by a single surgeon were compared. The groups consisted of the last 50 consecutive RRP (group 1) and RPP patients (group 2) and his first 50 RARP patients (group 3). He had significant experience in RRP and RPP and extensive training prior to performing RARP. The data was obtained from record review and patient survey. Patient demographics, operative parameters, pathological characteristics, complications, and functional outcomes… More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Christopher Nguan, Kevin Kwan, Mohammed Al Omar, Kenneth A. Beasley, Patrick P. W. Luke
Canadian Journal of Urology, Vol.14, No.3, pp. 6571-3576, 2007
Abstract Purpose: Laparoscopic pyeloplasty is a technically challenging procedure. Currently, several robotic surgical systems exist to overcome laparoscopic technical challenges confronted during pyeloplasty. We present a clinical comparison between three robotic surgical systems (Aesop, Zeus and da Vinci) in assisting laparoscopic pyeloplasty procedures.
Methods: From January 2002 to August 2005, 32 dismembered laparoscopic pyeloplasties were performed using three robotic surgical systems. The results of the initial six, five and nine laparoscopic robotic pyeloplasty procedures performed using the Aesop, Zeus and da Vinci platforms were compared. Data relating to the subsequent 12 pyeloplasties using the da Vinci system… More >

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CASE REPORT

Khalid Al-Taheini¹, Guido Filler², Michael Leonard¹
Canadian Journal of Urology, Vol.14, No.3, pp. 3577-3579, 2007
Abstract Prostatic calculi, though common in adult men, are rare in children. We report three cases of pediatric prostatic calculi seen at our clinic that were associated with hypercalciuria and elevated urinary calcium/ creatinine ratios. The patients had no symptoms from their prostatic calcification, but one patient had recurrent symptomatic renal calculi. In patients with prostatic calculi, determination of spot urine calcium/ creatinine ratios is recommended. If significant hypercalciuria is found, treatment to prevent upper urinary tract calculi may be considered. More >

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CASE REPORT

Mayank Mohan Agarwal, Shrawan K. Singh, Naveen C. Acharya, Uttam K. Mete, Arup K. Mandal
Canadian Journal of Urology, Vol.14, No.3, pp. 3580-3582, 2007
Abstract Advanced carcinoma prostate (CaP) commonly presents as bilateral ureteric obstruction. The management often requires androgen ablation along with temporary urinary diversion (percutaneous nephrostomy or ureteric catheterization) which is not infrequently associated with complications. Two patients of hormone-naïve CaP presented to our emergency department with oliguric renal failure due to bilateral ureteric obstruction and were treated with dialysis, ketoconazole (for androgen ablation) and corticosteroids; urinary diversion was not feasible in either at the time of presentation. Brisk diuresis occurred within 48 hours obviating the need of urinary diversion. Follow-up of these cases is presented and justification More >

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CASE REPORT

Constantinos Constantinidis¹, Georgios Koutalellis¹, Georgios Liapis², Constantinos Stravodimos¹, Paraskevi Alexandrou², Ioannis Adamakis¹
Canadian Journal of Urology, Vol.14, No.3, pp. 3583-3587, 2007
Abstract Background: Solitary fibrous tumors (SFTs) are rare spindle cell neoplasms that typically arise in the pleura. There are several reports of cases that arose from a variety of sites. SFT of the kidney is rare and, to our knowledge, only 25 cases have been published in the literature to date. SFTs in the kidney have similar morphologic and immunologic features and biologic behaviors as SFTs found elsewhere. In general, patients with SFTs of the kidney have a favorable prognosis.
Case: We report a case of SFT of the right kidney in a 26-year-old man. The tumor… More >

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RESIDENT’S CORNER

Lori M. Dulabon¹, Amar Singh¹, Frank Vogel², Alireza Moinzadeh¹
Canadian Journal of Urology, Vol.14, No.3, pp. 3588-3591, 2007
Abstract We report a case of a 19-year-old female who presented with right flank pain and microscopic hematuria.Three years earlier, she sustained a stab wound to the right flank and was managed conservatively. After being diagnosed with an enhancing renal mass using computed tomography (CT) scan, duplex ultrasound and angiography were performed revealing an intrarenal pseudoaneurysm. Endovascular coils were successfully employed to selectively embolize the pseudoaneurysm. More >

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RESIDENT’S CORNER

Carmin M. Kalorin, Farzeen Firoozi, Elise De, Carl Rosati
Canadian Journal of Urology, Vol.14, No.3, pp. 3592-3594, 2007
Abstract Introduction: Gunshot wounds to the bladder are not uncommon; however it is unusual that a bullet come to rest within the urinary bladder. Properly performed plain film cystography is trusted as a highly sensitive tool for identifying significant bladder injuries due to both blunt and penetrating trauma. Several reports suggest that cystography may be less sensitive in cases of gunshot wounds to the bladder.
Methods: We report our recent experience with a gunshot wound to the bladder and review the use of cystography in the diagnosis of bladder injury in this setting.
Results: Anecdotal case reports suggest More >

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RESIDENT’S CORNER

B. A. Vellayappan, H. Y. Tiong, W. J. Chua, D. T. Consigliere
Canadian Journal of Urology, Vol.14, No.3, pp. 3595-3597, 2007
Abstract We report a case of symptomatic seminal vesicle calculus following transurethral resection of ejaculatory duct. A 37-year-old male, who had previously undergone transurethral resection of ejaculatory duct, presented with perineal discomfort and graveluria. Computed tomography revealed a calculus situated within a dilated left seminal vesicle. The patient was treated with cystoscopy and litholapaxy of the seminal vesicle calculus. Although rare, our case demonstrates that seminal vesicle calculi formation can occur following treatment of ejaculatory duct obstruction, possibly secondary to urinary reflux and stasis. More >

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