Home / Journals / CJU / Vol.14, No.3, 2007
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  • Open AccessOpen Access

    EDITORIAL

    Prostate cancer detection: beware of the low PSA

    Gabriel P. Haas
    Canadian Journal of Urology, Vol.14, No.3, pp. 3534-3534, 2007
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    REVIEW

    The emerging role of epigenetics in urological cancers

    Kavitha Ramachandran1, Mark S. Soloway1,2, Rakesh Singal1,3, Murugesan Manoharan1,2
    Canadian Journal of Urology, Vol.14, No.3, pp. 3535-3541, 2007
    Abstract DNA methylation and histone modifications constitute the common epigenetic modifications in vertebrate genomes. The epigenetic changes are early event in the cancer development and are reversible. Over the last decade, the field of epigenetics has made considerable progress both in the diagnosis and treatment of variety of malignancies. Novel epigenetic markers are being studied, which have the potential as sensitive diagnostic and prognostic markers. DNA methylation has been identified as a powerful diagnostic tool in classification, detection and risk assessment of cancers. As DNA methylation is reversible, inhibitors of DNA methyl transferases and histone deacteylases More >

  • Open AccessOpen Access

    ARTICLE

    Appropriateness of testicular cancer management: a population-based cohort study

    Winson Y. Cheung1, Alain Demers2, Deloar Hossain3, Tim Owen4, Shahida Ahmed4, Piotr M. Czaykowski5
    Canadian Journal of Urology, Vol.14, No.3, pp. 3542-3550, 2007
    Abstract Objective: Testicular cancer is a highly curable malignancy of young men. Appropriate and timely management is critical to ensure optimal clinical outcomes. A 3-year population-based review of testicular cancer patients in Manitoba, Canada was undertaken to evaluate our management patterns.
    Methods: Men diagnosed with testicular cancer from 1998 to 2000 were identified from the Provincial Cancer Registry. Chart review was utilized to collect information on demographic characteristics, timelines of diagnostic and staging investigations, completeness of pathology reports, management, and outcomes.
    Results: Seventy-eight men were identified with 80 testicular cancers: 46 (59%) patients had 48 seminomas and 32… More >

  • Open AccessOpen Access

    ARTICLE

    Osteoporosis and fractures after androgen deprivation initiation for prostate cancer

    John B. Malcolm1, Ithaar H. Derweesh1, Matthew C. Kincade1, Christopher J. DiBlasio1, Kimberly D. Lamar2, Robert W. Wake1, Anthony L. Patterson1
    Canadian Journal of Urology, Vol.14, No.3, pp. 3551-3559, 2007
    Abstract Introduction: Androgen deprivation therapy (ADT) is widely utilized for treatment of localized and advanced prostate cancer (CaP). ADT is associated with increased rates of osteoporosis; however, its impact on fracture risk is not completely understood. We investigated incidence and predisposing factors for osteoporosis and fractures in a large, contemporary, single institution series of patients treated with ADT for CaP.
    Methods: We retrospectively reviewed medical records of all patients who received ADT for CaP between 1/1989 and 7/2005. Primary endpoints of investigation were osteoporosis and non-pathologic fractures. Independent variables included age, race, body mass index (BMI), pretreatment… More >

  • Open AccessOpen Access

    ARTICLE

    Feasibility of extended use of an electromagnetic lithotripter beyond the manufacturer’s recommended maintenance schedule

    Tony Y. H. Chen1, Yves Ponsot1, Martin Brouillette2, Jean-Pierre Tétrault3, Le Mai Tu1
    Canadian Journal of Urology, Vol.14, No.3, pp. 3560-3565, 2007
    Abstract Objectives: The study evaluates the effect of chronic usage, beyond the recommended maintenance schedule, on the efficacy of electromagnetic lithotripter. To our knowledge, there is no publication investigating the effect of chronic usage on the electromagnetic lithotripter, despite the maintenance schedule established by the manufacturers. Our goal is to verify if the acoustic parameters of the shock wave changed with usage, and if this change could be associated with change in clinical efficacy.
    Methods: This study lasted 18 months. Every 6 months the lithotripter's efficacy was evaluated in two ways: objectively and clinically. Objective efficacy was… More >

  • Open AccessOpen Access

    MINIMALLY INVASIVE AND ROBOTIC SURGERY

    Radical prostatectomy: a single surgeon comparison of retropubic, perineal, and robotic approaches

    Ronald S. Boris, Sanjeev A. Kaul, Richard C. Sarle, Hans J. Stricker
    Canadian Journal of Urology, Vol.14, No.3, pp. 3566-3570, 2007
    Abstract Objective: To compare perioperative, functional and oncological outcomes of a single surgeon's experience with retropubic (RRP), perineal (RPP), and robotic assisted (RARP) radical prostatectomy.
    Methods: Results from 150 radical prostatectomies performed by a single surgeon were compared. The groups consisted of the last 50 consecutive RRP (group 1) and RPP patients (group 2) and his first 50 RARP patients (group 3). He had significant experience in RRP and RPP and extensive training prior to performing RARP. The data was obtained from record review and patient survey. Patient demographics, operative parameters, pathological characteristics, complications, and functional outcomes… More >

  • Open AccessOpen Access

    MINIMALLY INVASIVE AND ROBOTIC SURGERY

    Robotic pyeloplasty: experience with three robotic platforms

    Christopher Nguan, Kevin Kwan, Mohammed Al Omar, Kenneth A. Beasley, Patrick P. W. Luke
    Canadian Journal of Urology, Vol.14, No.3, pp. 6571-3576, 2007
    Abstract Purpose: Laparoscopic pyeloplasty is a technically challenging procedure. Currently, several robotic surgical systems exist to overcome laparoscopic technical challenges confronted during pyeloplasty. We present a clinical comparison between three robotic surgical systems (Aesop, Zeus and da Vinci) in assisting laparoscopic pyeloplasty procedures.
    Methods: From January 2002 to August 2005, 32 dismembered laparoscopic pyeloplasties were performed using three robotic surgical systems. The results of the initial six, five and nine laparoscopic robotic pyeloplasty procedures performed using the Aesop, Zeus and da Vinci platforms were compared. Data relating to the subsequent 12 pyeloplasties using the da Vinci system… More >

  • Open AccessOpen Access

    CASE REPORT

    Hypercalciuria associated with pediatric prostatic calculi

    Khalid Al-Taheini1, Guido Filler2, Michael Leonard1
    Canadian Journal of Urology, Vol.14, No.3, pp. 3577-3579, 2007
    Abstract Prostatic calculi, though common in adult men, are rare in children. We report three cases of pediatric prostatic calculi seen at our clinic that were associated with hypercalciuria and elevated urinary calcium/ creatinine ratios. The patients had no symptoms from their prostatic calcification, but one patient had recurrent symptomatic renal calculi. In patients with prostatic calculi, determination of spot urine calcium/ creatinine ratios is recommended. If significant hypercalciuria is found, treatment to prevent upper urinary tract calculi may be considered. More >

  • Open AccessOpen Access

    CASE REPORT

    Non-interventional management of obstructive acute renal-failure in hormone-naïve prostate cancer

    Mayank Mohan Agarwal, Shrawan K. Singh, Naveen C. Acharya, Uttam K. Mete, Arup K. Mandal
    Canadian Journal of Urology, Vol.14, No.3, pp. 3580-3582, 2007
    Abstract Advanced carcinoma prostate (CaP) commonly presents as bilateral ureteric obstruction. The management often requires androgen ablation along with temporary urinary diversion (percutaneous nephrostomy or ureteric catheterization) which is not infrequently associated with complications. Two patients of hormone-naïve CaP presented to our emergency department with oliguric renal failure due to bilateral ureteric obstruction and were treated with dialysis, ketoconazole (for androgen ablation) and corticosteroids; urinary diversion was not feasible in either at the time of presentation. Brisk diuresis occurred within 48 hours obviating the need of urinary diversion. Follow-up of these cases is presented and justification More >

  • Open AccessOpen Access

    CASE REPORT

    A solitary fibrous tumor of the kidney in a 26-year-old man

    Constantinos Constantinidis1, Georgios Koutalellis1, Georgios Liapis2, Constantinos Stravodimos1, Paraskevi Alexandrou2, Ioannis Adamakis1
    Canadian Journal of Urology, Vol.14, No.3, pp. 3583-3587, 2007
    Abstract Background: Solitary fibrous tumors (SFTs) are rare spindle cell neoplasms that typically arise in the pleura. There are several reports of cases that arose from a variety of sites. SFT of the kidney is rare and, to our knowledge, only 25 cases have been published in the literature to date. SFTs in the kidney have similar morphologic and immunologic features and biologic behaviors as SFTs found elsewhere. In general, patients with SFTs of the kidney have a favorable prognosis.
    Case: We report a case of SFT of the right kidney in a 26-year-old man. The tumor… More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Intrarenal pseudoaneurysm presenting with microscopic hematuria and right flank pain

    Lori M. Dulabon1, Amar Singh1, Frank Vogel2, Alireza Moinzadeh1
    Canadian Journal of Urology, Vol.14, No.3, pp. 3588-3591, 2007
    Abstract We report a case of a 19-year-old female who presented with right flank pain and microscopic hematuria.Three years earlier, she sustained a stab wound to the right flank and was managed conservatively. After being diagnosed with an enhancing renal mass using computed tomography (CT) scan, duplex ultrasound and angiography were performed revealing an intrarenal pseudoaneurysm. Endovascular coils were successfully employed to selectively embolize the pseudoaneurysm. More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Cystogram may be unreliable in cases of gunshot wounds to the bladder: a case report

    Carmin M. Kalorin, Farzeen Firoozi, Elise De, Carl Rosati
    Canadian Journal of Urology, Vol.14, No.3, pp. 3592-3594, 2007
    Abstract Introduction: Gunshot wounds to the bladder are not uncommon; however it is unusual that a bullet come to rest within the urinary bladder. Properly performed plain film cystography is trusted as a highly sensitive tool for identifying significant bladder injuries due to both blunt and penetrating trauma. Several reports suggest that cystography may be less sensitive in cases of gunshot wounds to the bladder.
    Methods: We report our recent experience with a gunshot wound to the bladder and review the use of cystography in the diagnosis of bladder injury in this setting.
    Results: Anecdotal case reports suggest More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Seminal vesicle calculus after transurethral resection of ejaculatory duct

    B. A. Vellayappan, H. Y. Tiong, W. J. Chua, D. T. Consigliere
    Canadian Journal of Urology, Vol.14, No.3, pp. 3595-3597, 2007
    Abstract We report a case of symptomatic seminal vesicle calculus following transurethral resection of ejaculatory duct. A 37-year-old male, who had previously undergone transurethral resection of ejaculatory duct, presented with perineal discomfort and graveluria. Computed tomography revealed a calculus situated within a dilated left seminal vesicle. The patient was treated with cystoscopy and litholapaxy of the seminal vesicle calculus. Although rare, our case demonstrates that seminal vesicle calculi formation can occur following treatment of ejaculatory duct obstruction, possibly secondary to urinary reflux and stasis. More >

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