Open Access

EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.24, No.1, pp. 8603-8604, 2017
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LEGENDS IN UROLOGY

Isaac J. Powell
Canadian Journal of Urology, Vol.24, No.1, pp. 8605-8608, 2017
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REVIEW

Naşide Mangır¹, Levent Türkeri²
Canadian Journal of Urology, Vol.24, No.1, pp. 8609-8619, 2017
Abstract Introduction: Erectile dysfunction (ED) is still a common complication of radical prostatectomy. Current treatments of ED are mainly symptomatic. Mesenchymal stem cells (MSCs) have been widely investigated as a potential curative treatment. Although MSC therapy consistently improved erectile functions in the pre-clinical studies the initial expectations seem to be unmet. The aim of this study is to critically review the existing studies on use of stem cells in post-prostatectomy ED and understand factors that preclude clinical translation of the available evidence.
Materials and methods: A literature search for all pre-clinical and clinical studies investigating MSCs in the… More >

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ARTICLE

Leonard G. Gomella, Mark J. Mann, Ryan C. Cleary, Scott G. Hubosky, Demetrius H. Bagley, Adeep B. Thumar, Peter A. McCue, Costas D. Lallas, Edouard J. Trabulsi
Canadian Journal of Urology, Vol.24, No.1, pp. 8620-8626, 2017
Abstract Introduction: We evaluated the UroVysion (Abbott Molecular, IL, USA) fluorescence in situ hybridization (FISH) assay for the diagnosis of urothelial cancer in patients diagnosed with or suspected to have bladder, upper tract urothelial carcinoma (UTUC), and combined upper and lower tract urothelial carcinoma (BC).
Materials and methods: A single institution retrospective analysis comparing sensitivity, specificity, positive predictive value, and negative predictive values for FISH and urinary cytology. FISH within 6 months of endoscopic evaluation were obtained from outpatient voided urine samples. Our institutional pathology department confirmed pathologic disease from specimens obtained during endoscopic evaluations for lower tract… More >

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ARTICLE

Kyle A. Richards^1,2, Stacy Cesario¹, Amy H. Lim¹, Sara L. Best^1,2, Susan M. Deeren¹, Wade Bushman^1,2, Nasia Safdar³
Canadian Journal of Urology, Vol.24, No.1, pp. 8627-8633, 2017
Abstract Introduction: Urinalysis (UA) and urine culture (UCx) are commonly performed tests in the urology clinic. Many of these urine studies are performed prior to the patient visit may not always be indicated, thus contributing to unintended consequences such as antibiotic use and costs without enhancing patient care. Our objective was to perform a quality improvement initiative aimed to assess the utility of routine UA/UCx.
Materials and methods: The practice pattern at our site's Veteran Affairs (VA) urology clinic prior to 2014 was to obtain routine UA/UCx on most clinic visits prior to patient evaluation. Starting in 2014,… More >

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ARTICLE

Nazih Khater, Mohamed Keheila, Michelle Lightfoot, Jim Shen, Samuel Abourbih, Muhannad Alsyouf, Roger Li, D. Duane Baldwin
Canadian Journal of Urology, Vol.24, No.1, pp. 8634-8640, 2017
Abstract Introduction: Percutaneous nephrolithotomy (PCNL) is associated with significant variability in postoperative pain and subsequent narcotic use. The purpose of this study was to determine the factors associated with high narcotic use following PCNL.
Materials and methods: A single-center retrospective review of patients undergoing initial PCNL between 2004 and 2014 was performed. Preoperative, intraoperative and postoperative factors associated with postoperative narcotic usage were analyzed. The primary outcome variable was mean narcotic usage, standardized to intravenous morphine-equivalents. Patients in the lowest 75th percentile were compared to those in the highest 25th percentile. Univariate and multivariate statistical analyses were performed, with… More >

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ARTICLE

Benjamin J. King¹, Caleb J. Seufert¹, Zhamshid Okhunov², Nazih Khater³, D. Duane Baldwin³, Peter W. Callas¹, Kevan M. Sternberg¹
Canadian Journal of Urology, Vol.24, No.1, pp. 8641-8645, 2017
Abstract Introduction: To identify factors associated with stone composition in patients undergoing percutaneous nephrolithotomy (PCNL).
Material and methods: A retrospective analysis of patients who underwent PCNL at two academic institutions between 2002 and 2014. Stone composition, stone characteristics based on non-contrast computer tomography (NCCT), patient demographics, and the S.T.O.N.E nephrolithometry scores were compared. Stones were characterized as either infection or metabolic. Metabolic stones were classified as calcium phosphate-containing and all others.
Results: A total of 192 renal units underwent PCNL. Retrieved stones were found to be 75% (144) metabolic and 25% (48) infection by stone analysis. Of the metabolic… More >

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ARTICLE

Andrew Loblaw^1,2,3, Jack Barkin⁴, Roger Buckley⁵, Hans Chung^1,3, John Kell⁶, Rajiv Singal⁶, Jeff Spodek⁷, Danny Vesprini^1,3, Stanley Flax⁴
Canadian Journal of Urology, Vol.24, No.1, pp. 8646-8650, 2017
Abstract Introduction: There are numerous standard treatment options for men diagnosed with localized prostate cancer. Multidisciplinary consultation before decision-making is a consensus- and quality-based objective in Ontario. With the goals of working together more collaboratively and to provide higher quality information for patients at the time of decision-making, a prostate cancer community partnership consensus (PCPC) panel was formed among six partnering centers in the Greater Toronto Area.
Materials and methods: Five iterative meetings were held among 40 prostate cancer specialists (32 urologists and 8 radiation oncologists) who participate in multidisciplinary clinics. The meetings defined the goals of the… More >

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ARTICLE

Kevin A. Ostrowski¹, Nicholas N. Tadros¹, A. Scott Polackwich¹, R. Dale McClure², Eugene F. Fuchs¹, Jason C. Hedges¹
Canadian Journal of Urology, Vol.24, No.1, pp. 8651-8655, 2017
Abstract Introduction: To determine the factors used to make the decision between vasovasostomy (VV) and vasoepididymostomy (VE) by leaders performing microsurgical vasectomy reversal using a questionnaire.
Materials and methods: An online questionnaire was sent to all members of the Society for the Study of Male Reproduction (SSMR), a male reproduction subspecialty society of the AUA, using the SurveyMonkey platform.
Results: Sixty-seven surgeons responded to the questionnaire (27% of SSMR members). Of which 72% of members performed less than 50 vasectomy reversals per year. Also, 71% of members stated that less than 20% of their vasectomy reversals are vasoepididymostomies. When… More >

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ARTICLE

Yanqun Dong¹, Karen J. Ruth², Thomas M. Churilla¹, Rosalia Viterbo³, Mark L. Sobczak¹, Marc C. Smaldone³, David Y.T. Chen³, Robert G. Uzzo³, Mark H. Hallman¹, Eric M. Horwitz¹
Canadian Journal of Urology, Vol.24, No.1, pp. 8656-8662, 2017
Abstract Introduction: To evaluate if androgen deprivation therapy (ADT) improves outcomes for patients with localized, intermediate-risk prostate cancer treated with definitive external beam radiation therapy (EBRT) in the dose-escalated era.
Materials and methods: This is a retrospective study using a single institutional database. We included patients with localized, intermediate-risk prostate cancer treated with dose-escalated radiation therapy (RT) with 3D conformal radiotherapy or intensity-modulated radiotherapy (74-80 Gy in daily fraction of 1.8 Gy-2.0 Gy, or 70.2 Gy in daily fraction of 2.7 Gy) from 1992 to 2013. To further risk stratify the patients, PSA 10 ng/mL-20 ng/mL, Gleason 3+4,… More >

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COMMENTARY

Timothy N. Showalter
Canadian Journal of Urology, Vol.24, No.1, pp. 8663-8663, 2017
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ARTICLE

Allen F. Morey, Nirmish Singla, Maude Carmel, Alexandra Klein, Timothy J. Tausch, Jordan Siegel, Isamu Tachibana, Jeremy Scott
Canadian Journal of Urology, Vol.24, No.1, pp. 8664-8669, 2017
Abstract Introduction: We implemented a standardized Standing Cough Test (SCT) for assessment of men with post-prostatectomy incontinence (PPI) and stratified results according to an objective clinical grading scale in an attempt to facilitate male anti-incontinence surgical procedure selection.
Materials and methods: SCT was routinely performed during the initial outpatient consultation for PPI. Incontinence severity was recorded based on a novel Male Stress Incontinence Grading Scale (MSIGS) to stratify PPI. Each patient was assigned an incontinence grade score of 0 through 4 during the SCT. Men with mild stress urinary incontinence (SUI) (grades 0-2) were offered sling surgery while… More >

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RESIDENT’S CORNER

Raunak D. Patel, Colton Walker, Daniel J. Canter
Canadian Journal of Urology, Vol.24, No.1, pp. 8670-8672, 2017
Abstract Diffuse large B-cell lymphomas (DLBCL) are the most common lymphomas worldwide. They also appear to be the most common primary retroperitoneal lymphomas, but this presentation is relatively uncommon in the literature. Retroperitoneal masses, including lymphomas, often present with nonspecifc symptoms and laboratory values, necessitating radiographic assessment and consideration of mass biopsy prior to the initiation of treatment. Here we present a case of a primary retroperitoneal DLBCL as well as a review of the clinical presentation, imaging fndings, and differential diagnosis of such tumors. More >

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RESIDENT’S CORNER

Adam J. Rensing¹, Anand Mohapatra¹, Aaron M. Potretzke¹, Jennifer K. Sehn², Robert S. Figenshau¹
Canadian Journal of Urology, Vol.24, No.1, pp. 8673-8675, 2017
Abstract Lymphoepithelioma-like carcinoma (LELC) is a rare finding in the upper urinary tract. The presenting clinical findings mimic those of other more common upper-tract tumors, such as urothelial carcinoma. Preoperative imaging has not been shown to reliably predict the diagnosis of LELC. This tumor can be misdiagnosed as a reactive inflammatory lesion or lymphoma if the proper immunohistochemical stains for cytokeratin are not used. More >

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RESIDENT’S CORNER

Andrew A. Pridjian, Adam Sharbaugh, Amar Raval, David McGinnis
Canadian Journal of Urology, Vol.24, No.1, pp. 8676-8678, 2017
Abstract We present a rare case of fibrous pseudotumor of the tunica vaginalis. Discussion includes identification, histopathologic findings and management. Proper understanding and preoperative identification of this benign disease allows for an organ-sparing surgical approach. More >

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HOW I DO IT

Igor Sorokin¹, Murthy Chamarthy², Jeffrey A. Cadeddu^1,2
Canadian Journal of Urology, Vol.24, No.1, pp. 8679-8683, 2017
Abstract Percutaneous radiofrequency ablation has seen increased utilization secondary to the rising incidence of renal cell carcinoma. This has been shown to be an effective and durable treatment especially in the elderly comorbid patient. In this article, we describe our technique and factors related to successful outcomes. More >

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LETTER

Joan L. Robinson¹, Ann Jefferies², Thierry Lacaze³
Canadian Journal of Urology, Vol.24, No.1, pp. 8684-8687, 2017
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LETTER

Brian J. Morris¹, Jeffrey D. Klausner², John N. Krieger³, Bradley J. Willcox⁴, Pierre D. Crouse⁵, Neil Pollock⁶
Canadian Journal of Urology, Vol.24, No.1, pp. 8687-8692, 2017
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