Home / Journals / CJU / Vol.24, No.1, 2017
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  • Open AccessOpen Access

    EDITORIAL

    Prostate Cancer Statistics: Anything You Want Them To Be

    Leonard G. Gomella
    Canadian Journal of Urology, Vol.24, No.1, pp. 8603-8604, 2017
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    LEGENDS IN UROLOGY

    LEGENDS IN UROLOGY

    Isaac J. Powell
    Canadian Journal of Urology, Vol.24, No.1, pp. 8605-8608, 2017
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    REVIEW

    Stem cell therapies in post-prostatectomy erectile dysfunction: a critical review

    Naşide Mangır1, Levent Türkeri2
    Canadian Journal of Urology, Vol.24, No.1, pp. 8609-8619, 2017
    Abstract Introduction: Erectile dysfunction (ED) is still a common complication of radical prostatectomy. Current treatments of ED are mainly symptomatic. Mesenchymal stem cells (MSCs) have been widely investigated as a potential curative treatment. Although MSC therapy consistently improved erectile functions in the pre-clinical studies the initial expectations seem to be unmet. The aim of this study is to critically review the existing studies on use of stem cells in post-prostatectomy ED and understand factors that preclude clinical translation of the available evidence.
    Materials and methods: A literature search for all pre-clinical and clinical studies investigating MSCs in the… More >

  • Open AccessOpen Access

    ARTICLE

    Fluorescence in situ hybridization (FISH) in the diagnosis of bladder and upper tract urothelial carcinoma: the largest single-institution experience to date

    Leonard G. Gomella, Mark J. Mann, Ryan C. Cleary, Scott G. Hubosky, Demetrius H. Bagley, Adeep B. Thumar, Peter A. McCue, Costas D. Lallas, Edouard J. Trabulsi
    Canadian Journal of Urology, Vol.24, No.1, pp. 8620-8626, 2017
    Abstract Introduction: We evaluated the UroVysion (Abbott Molecular, IL, USA) fluorescence in situ hybridization (FISH) assay for the diagnosis of urothelial cancer in patients diagnosed with or suspected to have bladder, upper tract urothelial carcinoma (UTUC), and combined upper and lower tract urothelial carcinoma (BC).
    Materials and methods: A single institution retrospective analysis comparing sensitivity, specificity, positive predictive value, and negative predictive values for FISH and urinary cytology. FISH within 6 months of endoscopic evaluation were obtained from outpatient voided urine samples. Our institutional pathology department confirmed pathologic disease from specimens obtained during endoscopic evaluations for lower tract… More >

  • Open AccessOpen Access

    ARTICLE

    Utility of routine urinalysis and urine culture testing in an ambulatory urology clinic: a quality improvement initiative in a Veterans healthcare facility

    Kyle A. Richards1,2, Stacy Cesario1, Amy H. Lim1, Sara L. Best1,2, Susan M. Deeren1, Wade Bushman1,2, Nasia Safdar3
    Canadian Journal of Urology, Vol.24, No.1, pp. 8627-8633, 2017
    Abstract Introduction: Urinalysis (UA) and urine culture (UCx) are commonly performed tests in the urology clinic. Many of these urine studies are performed prior to the patient visit may not always be indicated, thus contributing to unintended consequences such as antibiotic use and costs without enhancing patient care. Our objective was to perform a quality improvement initiative aimed to assess the utility of routine UA/UCx.
    Materials and methods: The practice pattern at our site's Veteran Affairs (VA) urology clinic prior to 2014 was to obtain routine UA/UCx on most clinic visits prior to patient evaluation. Starting in 2014,… More >

  • Open AccessOpen Access

    ARTICLE

    Predictors of narcotic use after percutaneous nephrolithotomy

    Nazih Khater, Mohamed Keheila, Michelle Lightfoot, Jim Shen, Samuel Abourbih, Muhannad Alsyouf, Roger Li, D. Duane Baldwin
    Canadian Journal of Urology, Vol.24, No.1, pp. 8634-8640, 2017
    Abstract Introduction: Percutaneous nephrolithotomy (PCNL) is associated with significant variability in postoperative pain and subsequent narcotic use. The purpose of this study was to determine the factors associated with high narcotic use following PCNL.
    Materials and methods: A single-center retrospective review of patients undergoing initial PCNL between 2004 and 2014 was performed. Preoperative, intraoperative and postoperative factors associated with postoperative narcotic usage were analyzed. The primary outcome variable was mean narcotic usage, standardized to intravenous morphine-equivalents. Patients in the lowest 75th percentile were compared to those in the highest 25th percentile. Univariate and multivariate statistical analyses were performed, with… More >

  • Open AccessOpen Access

    ARTICLE

    Profile of metabolic and infectious stone-formers in a contemporary PCNL cohort

    Benjamin J. King1, Caleb J. Seufert1, Zhamshid Okhunov2, Nazih Khater3, D. Duane Baldwin3, Peter W. Callas1, Kevan M. Sternberg1
    Canadian Journal of Urology, Vol.24, No.1, pp. 8641-8645, 2017
    Abstract Introduction: To identify factors associated with stone composition in patients undergoing percutaneous nephrolithotomy (PCNL).
    Material and methods: A retrospective analysis of patients who underwent PCNL at two academic institutions between 2002 and 2014. Stone composition, stone characteristics based on non-contrast computer tomography (NCCT), patient demographics, and the S.T.O.N.E nephrolithometry scores were compared. Stones were characterized as either infection or metabolic. Metabolic stones were classified as calcium phosphate-containing and all others.
    Results: A total of 192 renal units underwent PCNL. Retrieved stones were found to be 75% (144) metabolic and 25% (48) infection by stone analysis. Of the metabolic… More >

  • Open AccessOpen Access

    ARTICLE

    Improving prostate cancer care collaboratively – a multidisciplinary, formal, consensus-based approach

    Andrew Loblaw1,2,3, Jack Barkin4, Roger Buckley5, Hans Chung1,3, John Kell6, Rajiv Singal6, Jeff Spodek7, Danny Vesprini1,3, Stanley Flax4
    Canadian Journal of Urology, Vol.24, No.1, pp. 8646-8650, 2017
    Abstract Introduction: There are numerous standard treatment options for men diagnosed with localized prostate cancer. Multidisciplinary consultation before decision-making is a consensus- and quality-based objective in Ontario. With the goals of working together more collaboratively and to provide higher quality information for patients at the time of decision-making, a prostate cancer community partnership consensus (PCPC) panel was formed among six partnering centers in the Greater Toronto Area.
    Materials and methods: Five iterative meetings were held among 40 prostate cancer specialists (32 urologists and 8 radiation oncologists) who participate in multidisciplinary clinics. The meetings defined the goals of the… More >

  • Open AccessOpen Access

    ARTICLE

    Factors and practice patterns that affect the decision for vasoepididymostomy

    Kevin A. Ostrowski1, Nicholas N. Tadros1, A. Scott Polackwich1, R. Dale McClure2, Eugene F. Fuchs1, Jason C. Hedges1
    Canadian Journal of Urology, Vol.24, No.1, pp. 8651-8655, 2017
    Abstract Introduction: To determine the factors used to make the decision between vasovasostomy (VV) and vasoepididymostomy (VE) by leaders performing microsurgical vasectomy reversal using a questionnaire.
    Materials and methods: An online questionnaire was sent to all members of the Society for the Study of Male Reproduction (SSMR), a male reproduction subspecialty society of the AUA, using the SurveyMonkey platform.
    Results: Sixty-seven surgeons responded to the questionnaire (27% of SSMR members). Of which 72% of members performed less than 50 vasectomy reversals per year. Also, 71% of members stated that less than 20% of their vasectomy reversals are vasoepididymostomies. When… More >

  • Open AccessOpen Access

    ARTICLE

    The need for androgen deprivation therapy in patients with intermediate-risk prostate cancer treated with dose-escalated external beam radiation therapy

    Yanqun Dong1, Karen J. Ruth2, Thomas M. Churilla1, Rosalia Viterbo3, Mark L. Sobczak1, Marc C. Smaldone3, David Y.T. Chen3, Robert G. Uzzo3, Mark H. Hallman1, Eric M. Horwitz1
    Canadian Journal of Urology, Vol.24, No.1, pp. 8656-8662, 2017
    Abstract Introduction: To evaluate if androgen deprivation therapy (ADT) improves outcomes for patients with localized, intermediate-risk prostate cancer treated with definitive external beam radiation therapy (EBRT) in the dose-escalated era.
    Materials and methods: This is a retrospective study using a single institutional database. We included patients with localized, intermediate-risk prostate cancer treated with dose-escalated radiation therapy (RT) with 3D conformal radiotherapy or intensity-modulated radiotherapy (74-80 Gy in daily fraction of 1.8 Gy-2.0 Gy, or 70.2 Gy in daily fraction of 2.7 Gy) from 1992 to 2013. To further risk stratify the patients, PSA 10 ng/mL-20 ng/mL, Gleason 3+4,… More >

  • Open AccessOpen Access

    COMMENTARY

    Commentary: In search of answers regarding the benefits and harms of short term ADT for intermediate-risk prostate cancer

    Timothy N. Showalter
    Canadian Journal of Urology, Vol.24, No.1, pp. 8663-8663, 2017
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    ARTICLE

    Standing cough test for evaluation of post-prostatectomy incontinence: a pilot study

    Allen F. Morey, Nirmish Singla, Maude Carmel, Alexandra Klein, Timothy J. Tausch, Jordan Siegel, Isamu Tachibana, Jeremy Scott
    Canadian Journal of Urology, Vol.24, No.1, pp. 8664-8669, 2017
    Abstract Introduction: We implemented a standardized Standing Cough Test (SCT) for assessment of men with post-prostatectomy incontinence (PPI) and stratified results according to an objective clinical grading scale in an attempt to facilitate male anti-incontinence surgical procedure selection.
    Materials and methods: SCT was routinely performed during the initial outpatient consultation for PPI. Incontinence severity was recorded based on a novel Male Stress Incontinence Grading Scale (MSIGS) to stratify PPI. Each patient was assigned an incontinence grade score of 0 through 4 during the SCT. Men with mild stress urinary incontinence (SUI) (grades 0-2) were offered sling surgery while… More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Acase report of a renal diffuse B-cell lymphoma

    Raunak D. Patel, Colton Walker, Daniel J. Canter
    Canadian Journal of Urology, Vol.24, No.1, pp. 8670-8672, 2017
    Abstract Diffuse large B-cell lymphomas (DLBCL) are the most common lymphomas worldwide. They also appear to be the most common primary retroperitoneal lymphomas, but this presentation is relatively uncommon in the literature. Retroperitoneal masses, including lymphomas, often present with nonspecifc symptoms and laboratory values, necessitating radiographic assessment and consideration of mass biopsy prior to the initiation of treatment. Here we present a case of a primary retroperitoneal DLBCL as well as a review of the clinical presentation, imaging fndings, and differential diagnosis of such tumors. More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Lymphoepithelioma-like carcinoma of the ureter: a rare presentation, synchronous with conventional urothelial carcinoma

    Adam J. Rensing1, Anand Mohapatra1, Aaron M. Potretzke1, Jennifer K. Sehn2, Robert S. Figenshau1
    Canadian Journal of Urology, Vol.24, No.1, pp. 8673-8675, 2017
    Abstract Lymphoepithelioma-like carcinoma (LELC) is a rare finding in the upper urinary tract. The presenting clinical findings mimic those of other more common upper-tract tumors, such as urothelial carcinoma. Preoperative imaging has not been shown to reliably predict the diagnosis of LELC. This tumor can be misdiagnosed as a reactive inflammatory lesion or lymphoma if the proper immunohistochemical stains for cytokeratin are not used. More >

  • Open AccessOpen Access

    RESIDENT’S CORNER

    Paratesticular fibrous pseudotumor

    Andrew A. Pridjian, Adam Sharbaugh, Amar Raval, David McGinnis
    Canadian Journal of Urology, Vol.24, No.1, pp. 8676-8678, 2017
    Abstract We present a rare case of fibrous pseudotumor of the tunica vaginalis. Discussion includes identification, histopathologic findings and management. Proper understanding and preoperative identification of this benign disease allows for an organ-sparing surgical approach. More >

  • Open AccessOpen Access

    HOW I DO IT

    How I do it: percutaneous radiofrequency ablation (RFA)

    Igor Sorokin1, Murthy Chamarthy2, Jeffrey A. Cadeddu1,2
    Canadian Journal of Urology, Vol.24, No.1, pp. 8679-8683, 2017
    Abstract Percutaneous radiofrequency ablation has seen increased utilization secondary to the rising incidence of renal cell carcinoma. This has been shown to be an effective and durable treatment especially in the elderly comorbid patient. In this article, we describe our technique and factors related to successful outcomes. More >

  • Open AccessOpen Access

    LETTER

    Letter to the Editor – Re: Canadian Pediatrics Society position statement on newborn circumcision: a risk-benefit analysis revisited

    Joan L. Robinson1, Ann Jefferies2, Thierry Lacaze3
    Canadian Journal of Urology, Vol.24, No.1, pp. 8684-8687, 2017
    Abstract This article has no abstract. More >

  • Open AccessOpen Access

    LETTER

    Reply by Authors – Re: Canadian Pediatrics Society position statement on newborn circumcision: a risk-benefit analysis revisited

    Brian J. Morris1, Jeffrey D. Klausner2, John N. Krieger3, Bradley J. Willcox4, Pierre D. Crouse5, Neil Pollock6
    Canadian Journal of Urology, Vol.24, No.1, pp. 8687-8692, 2017
    Abstract This article has no abstract. More >

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