Open Access

EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.22, No.5, pp. 7942-7943, 2015
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LEGENDS IN UROLOGY

Richard G. Middleton
Canadian Journal of Urology, Vol.22, No.5, pp. 7944-7946, 2015
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REVIEW

Alfredo Harb-De la Rosa, Matthew Acker, Raj A. Kumar, Murugesan Manoharan
Canadian Journal of Urology, Vol.22, No.5, pp. 7947-7951, 2015
Abstract Introduction: Bladder cancer is the sixth most common cancer in the Western world. Patients with bladder cancer require close monitoring, which may include frequent cystoscopy and urine cytology. Such monitoring results in significant health care cost. The application of epigenetics may allow for a risk adapted approach and more cost-effective method of monitoring. A number of epigenetic changes have been described for many cancer sites, including the urinary bladder. In this review, we discuss the use of epigenetics in bladder cancer and the potential diagnostic and therapeutic applications.
Materials and methods: A comprehensive search of the English… More >

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ARTICLE

Jerry G. Blaivas^1,2,3, Johnson F. Tsui^2,4, Gabriel Mekel^2,5, Matthew S. Benedon², Belinda Li⁶, Fara M. Friedman³, James M. Weinberger^2,7, Jeremy Weedon³, Jeffrey P. Weiss^2,3
Canadian Journal of Urology, Vol.22, No.5, pp. 7952-7958, 2015
Abstract Introduction: To develop and validate a lower urinary tract symptom score (LUTSS) as a measure of lower urinary tract symptom (LUTS) severity and a treatment outcome tool in adults.
Materials and methods: An expert panel was convened to develop the LUTSS questionnaire. Content validity was achieved by obtaining subject and expert feedback from two prospective drafts. Subjects were divided into three groups: normal, LUTS and overactive bladder (OAB). Questionnaire was administered on two separate occasions within 1-2 weeks. Test-retest reliability, internal consistency, discriminant validity, criterion validity and responsiveness to change were also assessed.
Results: The questionnaire contains 14… More >

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ARTICLE

Ilan J. Safr^1,2, Adam B. Shrewsberry^1,2, Isabella M. Issa³, Kenneth Ogan^1,2, Chad W. M. Ritenour^1,2, Jerry Sullivan^1,2, Muta M. Issa^1,2
Canadian Journal of Urology, Vol.22, No.5, pp. 7959-7964, 2015
Abstract Introduction: The study objective was to determine the impact of remote monitoring and supervision (RMS) in integrated endourology suites (IES) on residents achieving endoscopic training milestones.
Materials and methods: Twenty-one urology residents evaluated RMS in IES using a 25-question survey. IES provided audio-visual communication for faculty to supervise residents remotely. Questionnaire used a linear visual scale of 1-10 to assess acceptability (8 questions), impact on training (10 questions), supervision level (1 question), and pre- and post-training milestone self-assessments (6 questions). Improvements in Patient Care Milestone #7 (upper/lower tract endoscopic procedures) and Patient Care Milestone #9 (office-based procedures)… More >

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ARTICLE

Seyed Saeid Dianat¹, H. Ballentine Carter^2,4, Edward M. Schaeffer^2,4, Ulrike M. Hamper^1,2, Jonathan I. Epstein^2,3,4, Katarzyna J. Macura^1,2,4
Canadian Journal of Urology, Vol.22, No.5, pp. 7965-7972, 2015
Abstract Introduction: Purpose of this pilot study was to correlate quantitative parameters derived from the multiparametric magnetic resonance imaging (MP-MRI) of the prostate with results from MRI guided transrectal ultrasound (MRI/TRUS) fusion prostate biopsy in men with suspected prostate cancer.
Materials and methods: Thirty-nine consecutive patients who had 3.0T MP-MRI and subsequent MRI/TRUS fusion prostate biopsy were included and 73 MRI-identified targets were sampled by 177 cores. The pre-biopsy MP-MRI consisted of T2-weighted, diffusion weighted (DWI), and dynamic contrast enhanced (DCE) images. The association of quantitative MRI measurements with biopsy histopathology findings was assessed by Mann-Whitney U-test and… More >

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ARTICLE

Jonathan A. Wu¹, Tin C. Ngo¹, Cappy Rothman², Benjamin N. Breyer³, Michael L. Eisenberg¹
Canadian Journal of Urology, Vol.22, No.5, pp. 7973-7977, 2015
Abstract Introduction: To use Google Insights search volume and publicly available economic indicators to test the hypothesis that sperm, egg, and blood donations increase during economic downturns and to demonstrate the feasibility of using Google search volume data to predict national trends in actual sperm, egg, and blood donations rates.
Materials and methods: Cross-correlation statistical analysis comparing Google search data for terms relating to blood, egg, and sperm donations with various economic indicators including the S&P 500 closing values, gross domestic product (GDP), the U.S. Index of Leading Indicators (U.S. Leading Index), gross savings rate, mortgage interest rates,… More >

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ARTICLE

Frank T. D’Arcy¹, Nathan Lawrentschuk^1,2,3, Rustom P. Manecksha^1,4, David R. Webb¹
Canadian Journal of Urology, Vol.22, No.5, pp. 7978-7983, 2015
Abstract Introduction: Percutaneous nephrolithotomy (PCNL) was described in the 1980s and revolutionized the treatment of stone disease. The crucial component to this surgery is satisfactory track creation. We examine how the development and production in the 1980s of a single stage dilator (SSD) subsequently modified for pediatric PCNL has become the ideal access tool for mini percutaneous nephrolithotomy (mPCNL) today.
Materials and methods: The conception, production, scientific and clinical development of the original SSD is described. The pitfalls of track dilation in general according to method of dilation are also discussed and outlined.
Results: This study provides evidence clarifying More >

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ARTICLE

Adam B. Althaus, Ostap Dovirak, Peter Chang, Kimberly N. Taylor, Thomas D. O’Halloran, Andrew A. Wagner
Canadian Journal of Urology, Vol.22, No.5, pp. 7984-7989, 2015
Abstract Introduction: Continuation of antiplatelet medications through major urologic surgery may increase the risk of intraoperative and postoperative bleeding complications. However, withdrawal of antiplatelet therapy may place some patients at high risk of serious cardiovascular or cerebrovascular complications. We assess the feasibility of performing robotic partial nephrectomy (RPN) in patients maintained on aspirin or dual antiplatelet therapy with aspirin and clopidogrel.
Material and methods: Perioperative data was collected prospectively on 230 subjects undergoing RPN enrolled in an IRB approved quality of life study. We analyzed subjects who were maintained on either aspirin alone or both aspirin and clopidogrel… More >

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ARTICLE

Brenton Winship, Neal Patel, Lang Nguyen, Sean Bhalla, Alice Semerjian, Thomas Jarrett
Canadian Journal of Urology, Vol.22, No.5, pp. 7990-7994, 2015
Abstract Introduction: The development of deep venous thrombosis (DVT) or pulmonary embolism (PE) following urologic surgery is a life threatening, but largely preventable complication. Patients undergoing partial nephrectomy are at increased risk for the development of DVT or PE as they often possess multiple risk factors including malignancy, advanced age, and prolonged surgical time. This risk can be significantly reduced by administration of perioperative subcutaneous heparin (SQH), however many surgeons feel this is contraindicated due to potential blood loss and related complications.
Materials and methods: The medical records of 293 consecutive patients undergoing planned open, laparoscopic, or robotic… More >

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PEDIATRIC UROLOGY

Maria Voznesensky¹, Christopher Mutter², Matthew Hayn¹, Thomas Kinkead¹, Brian Jumper¹
Canadian Journal of Urology, Vol.22, No.5, pp. 7995-7999, 2015
Abstract Introduction: Circumcision is the most commonly performed surgical procedures in male children. Maine is one of 18 states in the United States which does not pay for neonatal circumcisions.
The aim of this study was to perform outcomes and cost analysis of a sutureless circumcision technique versus circumcision using sutures. Specifically, we evaluated Dermaflex (2-octyl cyanoacrylate, 2-OCA) surgical glue circumcision as a cost effective, faster, and safe alternative to traditional suture circumcision.
Materials and methods: Our study was a nonrandomized series. We collected the operative details prospectively, abstracted clinical outcomes retrospectively, and performed data analysis retrospectively. One… More >

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RESIDENT’S CORNER

John M. Lacy¹, Raevti Bole², Lauren Hendrix¹, Stephen Strup³
Canadian Journal of Urology, Vol.22, No.5, pp. 8000-8002, 2015
Abstract Giant benign prostatic hyperplasia is a rare pathology of the prostate gland. Here we report the successful removal of the ninth largest prostate ever reported. This 65-year-old patient presented with acute urinary retention secondary to a bulky left prostatic mass identified on pelvic magnetic resonance imaging (MRI). His preoperative prostate-specific antigen (PSA) value was 44 ng/mL; preoperative biopsies were negative for malignancy. Open radical retropubic prostatectomy was performed and the resulting prostatic mass was measured at 13.5 cm x 11.5 cm x 5.2 cm, weighing 708 g including the prostate. The patient tolerated the procedure More >

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RESIDENT’S CORNER

Kellen Choi¹, Nathan Hale¹, Daniel Olsen², Samuel Deem¹
Canadian Journal of Urology, Vol.22, No.5, pp. 8003-8005, 2015
Abstract Warty carcinoma variant of squamous cell carcinoma of the penis is a rare condition, making up 7% to 10% of all penilecarcinomas.Wepresentacaseofwartycarcinoma variant of squamous cell carcinoma of the penis in a 43-year-old Caucasian. The tumor presented in a locally invasive manner, requiring a total penectomy. The primary lesion measured over 15 cm x 16 cm, covering the entire perineum. The clinical features, diagnosis, surgical treatment and pathology are reviewed. In light of the locally invasive nature of warty carcinoma of the penis and high recurrence rate, early diagnosis and aggressive treatment is necessary for More >

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RESIDENT’S CORNER

Jason Frankel, Gregory Murphy, Peter Haddock, Max Jackson, Anoop Meraney
Canadian Journal of Urology, Vol.22, No.5, pp. 8006-8008, 2015
Abstract A 46-year-old male with a history of hypertension presented with symptoms of persistent abdominal fullness and a non-pulsatile abdominal mass. Subsequent computed tomographic angiography studies revealed the presence multiple large renal aneurysms from the segmental branches of the renal artery and an enlarged hydronephrotic kidney with minimal parenchyma. The renal deterioration appeared to be as a result of an obstruction caused by the large intra-renal aneurysms at the level of the renal calyces. Since the right kidney had no function, an open radical nephrectomy was subsequently performed without complications at 3 months follow up. More >

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RESIDENT’S CORNER

Alexander C. Haab, Isabelle S. Keller, Christian Padevit, Hubert John
Canadian Journal of Urology, Vol.22, No.5, pp. 8009-8011, 2015
Abstract Ureteral stenosis due to reactivation of the BK virus (BKV) in a state of immunodeficiency is very rare. More common is the appearance of a hemorrhagic cystitis. This report not only shows bilateral ureteral stenosis after bone marrow transplantation, but also presents severe complications as chronic pelvic pain and impaired kidney function as well as irreparable damage to the whole urinary tract leading to nephroureterectomy, subtrigonal cystectomy and orthotopic ileal neobladder. Finally renal transplantation was required. To our knowledge this is the first case in the literature where such a severe course of BKV associated More >

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ABSTRACT

Canadian Journal of Urology, Vol.22, No.5, pp. 8012-8041, 2015
Abstract This article has no abstract. More >

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