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RESIDENT’S CORNER

BK virus associated pronounced hemorrhagic cystoureteritis after bone marrow transplantation

Alexander C. Haab, Isabelle S. Keller, Christian Padevit, Hubert John

Department of Urology, EBU Certified Training Centre, Kantonsspital Winterthur, Switzerland
Address correspondence to Dr. Alexander C. Haab, Department of Urology, EBU Certified Training Centre, Kantonsspital Winterthur, Brauerstrasse 15, Postfach 834, 8401 Winterthur, Switzerland

Canadian Journal of Urology 2015, 22(5), 8009-8011.

Abstract

Ureteral stenosis due to reactivation of the BK virus (BKV) in a state of immunodeficiency is very rare. More common is the appearance of a hemorrhagic cystitis. This report not only shows bilateral ureteral stenosis after bone marrow transplantation, but also presents severe complications as chronic pelvic pain and impaired kidney function as well as irreparable damage to the whole urinary tract leading to nephroureterectomy, subtrigonal cystectomy and orthotopic ileal neobladder. Finally renal transplantation was required. To our knowledge this is the first case in the literature where such a severe course of BKV associated hemorrhagic cystoureteritis is described.

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