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EDITORIAL

Kevin R. Loughlin
Canadian Journal of Urology, Vol.25, No.5, pp. 9467-9468, 2018
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LEGENDS IN UROLOGY

Lawson Douglas
Canadian Journal of Urology, Vol.25, No.5, pp. 9469-9471, 2018
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BOOK REVIEW

Sam S. Chang, Michael S. Cookson
Canadian Journal of Urology, Vol.25, No.5, pp. 9472-9472, 2018
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ARTICLE

Scott G. Erpelding¹, Adam Dugan², Sudhir Isharwal³, Stephen Strup¹, Andrew James¹, Shubham Gupta¹
Canadian Journal of Urology, Vol.25, No.5, pp. 9473-9479, 2018
Abstract Introduction: We sought to elucidate outcomes and risks associated with cystectomy and urinary diversion for benign urological conditions compared to malignant conditions.
Materials and methods: We identified patients who underwent cystectomy and urinary diversion for benign and malignant diseases through the American College of Surgeons National Surgery Quality Improvement Program database for the period 2007-2015. Patients were selected for inclusion based upon their current procedure terminology and International Classification of Disease, Ninth Revision codes. Primary outcome was 30-day morbidity, including return to the operating room (OR); infectious, respiratory, and/or cardiovascular complications; readmission to the hospital; and mortality.… More >

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ARTICLE

Salvatore Siracusano¹, Tommaso Silvestri², Silvia Bassi¹, Antonio Benito Porcaro¹, Maria Angela Cerruto¹, Renato Talamini³, Walter Artibani¹
Canadian Journal of Urology, Vol.25, No.5, pp. 9480-9485, 2018
Abstract Introduction: To evaluate health-related quality of life (HRQoL) in patients with non-muscle invasive bladder cancer (NMIBC) during the induction phase of intravesical instillations with BCG or MMC.
Materials and methods: HRQoL was measured by two questionnaires from EORTC (QLQ-C30 and QLQ-BLS24), stratifying results by gender, age, and therapy at the start of the therapy (T0), at the last instillation (T1), and at 3 months after T1 (T2). The persistence of QoL-related side effects after 3 months from the end of the induction cycle was evaluated.
Results: We enrolled 108 naïve patients, and 103 patients self-completed the questionnaires. Treatment… More >

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ARTICLE

Erica L. Ditkoff¹, Marissa Theofanides², Carrie Mlynarczyk Aisen², Casey G. Kowalik³, Joshua A. Cohn³, Wilson Sui³, Matthew Rutman², Rony A. Adam⁴, Roger R. Dmochowski³, Kimberly L. Cooper²
Canadian Journal of Urology, Vol.25, No.5, pp. 9486-9496, 2018
Abstract Introduction: Evidence-based screening and treatment for bacteriuria is crucial to prevent increasing antibiotic resistance. The Infectious Disease Society of America (IDSA) previously released guidelines on the management of asymptomatic bacteriuria (ASB) and uncomplicated urinary tract infections (UTIs) in women. The study’s objective was to assess physicians’ practices in managing women with bacteriuria relative to these guideline recommendations.
Materials and methods: Cross-sectional data from physicians were collected using an anonymous questionnaire. Multivariable logistic regression analyses identified independent predictors of adherence to guidelines.
Results: Data were collected from 260 physicians. Over half of physicians surveyed were unfamiliar with IDSA guidelines… More >

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ARTICLE

Priyanka Bearelly^1,*, Claire Lis^2,*, James Trussler^2,, Mark H. Katz¹, Richard K. Babayan¹, David S. Wang¹
Canadian Journal of Urology, Vol.25, No.5, pp. 9497-9502, 2018
Abstract Introduction: This study aims to compare outcomes of percutaneous nephrolithotomy (PCNL) performed with a nephrostomy tube placed prior to surgery versus access obtained at the time of surgery.
Materials and methods: Between March 2005 and August 2014, 233 PCNLs were performed. One hundred and nine of those cases underwent placement of nephrostomy tubes at least 1 day prior to surgery (Group A), and the remaining 124 cases were performed in which access was obtained at the time of PCNL (Group B). Patient demographics, comorbidities, stone size, sepsis rates, and additional complication rates, including bleeding and inability to… More >

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ARTICLE

Charlotte K. Roberts¹, Jonathan S. Ellison², Omar Aboumarzouk¹, Mohamed Abd-Alazeez¹, Francis X. Keeley, Jr¹
Canadian Journal of Urology, Vol.25, No.5, pp. 9503-9508, 2018
Abstract Introduction: Renal duplication is a relatively common congenital abnormality of the urinary tract, but symptomatic duplex kidney is a rare presentation in adults. Traditionally, the treatment of choice for poorly functioning moiety has been heminephrectomy. There is extensive literature detailing the outcomes of minimally invasive upper pole heminephrectomy, but comparatively little published regarding lower pole resection, especially in adult patients. We present a series of 13 patients who underwent minimally invasive heminephrectomy for duplex kidney.
Materials and methods: Over a 6-year period (2011-2017), 13 patients at a single center underwent laparoscopic heminephrectomy for symptomatic duplex kidney with… More >

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ARTICLE

Daniel Taussky^1,2, Felix Preisser^3,4, Pierre I. Karakiewicz^1,5, Derya Tilki^3,4, Carole Lambert^1,2, Jean-Paul Bahary^1,2, Guila Delouya^1,2, Robert Wistaff^2,6, Mikhael Laskine^2,6, Paul Van Nguyen^2,6, Madeleine Durand^2,6, Fred Saad⁵
Canadian Journal of Urology, Vol.25, No.5, pp. 9509-9515, 2018
Abstract Introduction: Conflicting data exists on the influence of metformin on prostate cancer. We investigated the importance of metformin in patients treated with radiotherapy or brachytherapy.
Materials and methods: All patients from a large institutionalized database, treated for primary localized prostate cancer with either brachytherapy or external-beam radiotherapy ± androgen deprivation therapy were identified. Groups were compared by Kaplan–Meier analyses and Cox regression models. Multivariate analysis was adjusted for CAPRA-Score, type of treatment, and age.
Results: A total of 2441 patients with complete data was identified. Among them, 382 patients (16% of total) were diabetic. Two hundred eighty-one of… More >

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ARTICLE

Rachael Sussman^1,2,*, Filipe L.F. Carvalho^1,2,*, Andrew Harbin¹, Choayi Zheng¹, John H. Lynch¹, Lambros Stamatakis², Jonathan Hwang², Stephen B. Williams³, Jim C. Hu⁴, Keith J. Kowalczyk¹
Canadian Journal of Urology, Vol.25, No.5, pp. 9516-9524, 2018
Abstract Introduction: The utility of radical prostatectomy (RP) for locally-advanced prostate cancer remains unknown. Retrospective data has shown equivalent oncologic outcomes compared to radiation therapy (RT). RP may provide local tumor control and prevent secondary interventions from local invasion, and may decrease costs.
Materials and methods: Using SEER-Medicare data from 1995-2011, we identified men with locally-advanced prostate cancer undergoing RP or RT. Rates of post-treatment diagnoses and interventions were identified using ICD-9 and CPT codes. Skeletal related events (SRE), androgen deprivation therapy (ADT) utilization, all-cause mortality, prostate cancer-specific mortality, and costs were compared.
Results: A total of 8367 men… More >

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RESIDENT’S CORNER

Jacqueline Zillioux¹, Matthew DiLizia², Basil Schaheen³, Rudolph Rustin³, Tracey L. Krupski¹
Canadian Journal of Urology, Vol.25, No.5, pp. 9525-9526, 2018
Abstract Atezolizumab is a promising immunotherapy for advanced urothelial carcinoma. Like other immune checkpoint inhibitors, it can produce rare immune-related adverse events (IRAEs). Here we present the recent case of a patient with metastatic bladder cancer who developed diarrhea and abdominal pain months after beginning atezolizumab therapy. He presented to our institution with an ileal perforation secondary to atezolizumabinduced enterocolitis. After surgical repair, the patient’s condition improved, and he was discharged. We discuss the management of atezolizumab-induced enterocolitis, including the importance of early recognition and intervention to prevent more devastating complications. More >

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RESIDENT’S CORNER

Edward J. Park¹, Arden Plumb², Ryan Powers¹, Patricia Vidal^1,3, Sarah Psutka^1,3
Canadian Journal of Urology, Vol.25, No.5, pp. 9527-9529, 2018
Abstract A 37-year-old female presented with abdominal pain. An abdominal computed tomography scan demonstrated a 10 cm x 13 cm left renal mass. An open adrenal-sparing radical nephrectomy was performed. The pathological diagnosis was epithelioid angiomyolipoma. Five-year surveillance did not demonstrate recurrence of disease. However, a 1.8 cm x 2.5 cm mass on the rectus abdominis muscle was identifed after 5 years. Biopsy of the mass demonstrated histologic findings consistent with the primary tumor. Herein, we report a case of metastatic renal epithelioid angiomyolipoma to the rectus abdominis muscle more than 5 years after resection of More >

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RESIDENT’S CORNER

Mounsif Azizi, Charles C. Peyton, Philippe E. Spiess
Canadian Journal of Urology, Vol.25, No.5, pp. 9530-9533, 2018
Abstract A 26-year-old male with a personal history of schizophrenia initially presented with a 13 cm pelvic mass corresponding to a cryptorchidic testis. The patient was treated with primary and second-line chemotherapy for metastatic germ-cell tumor followed by surgical consolidation. Final pathology revealed a primitive neuroectodermal tumor (PNET) mixed with mature teratoma. Despite multidisciplinary management, significant patient noncompliance led to inadequate follow up and treatment delays ultimately resulting in death. To our knowledge, this is the only reported case of teratoma with malignant transformation arising from an untreated congenital undescended testicle. More >

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ABSTRACT

Canadian Journal of Urology, Vol.25, No.5, pp. 9534-9567, 2018
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