Open Access

EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.26, No.5, pp. 9905-9905, 2019
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LEGENDS IN UROLOGY

H. Ballentine Carter
Canadian Journal of Urology, Vol.26, No.5, pp. 9906-9907, 2019
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ARTICLE

Mehrdad Alemozaffar¹, Kenneth Ogan¹, Christopher P. Filson¹, Dattatraya Patil¹, Grace Lee², Daniel J. Canter³, Gordon Hong⁴, Viraj A. Master¹
Canadian Journal of Urology, Vol.26, No.5, pp. 9908-9915, 2019
Abstract Introduction: The use of an electrocautery device (monopolar loop) for patients undergoing transurethral resection of bladder tumors (TURBT) is standard of care. The aim of this study is to establish non-inferiority of complication rates for a bipolar energy device, the PK PlasmaButton (PK Button), when compared to the monopolar loop.
Materials and methods: Seventy-eight subjects (41 monopolar loop and 37 PK Button), were enrolled in a single-center, prospective, randomized study with cystoscopically detected bladder tumors that were judged endoscopically resectable with only one trip into the operating room. Intra and postoperative data on complication rates, operative time,… More >

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ARTICLE

Anand V. Badri¹, Nikhil Waingankar², Kristin Edwards³, Alexander Kutikov¹, Rosaleen B. Parsons³, David Y. Chen¹, Marc C. Smaldone¹, Rosalia Viterbo¹, Richard E. Greenberg¹, Robert G. Uzzo¹
Canadian Journal of Urology, Vol.26, No.5, pp. 9916-9921, 2019
Abstract Introduction: Current radiographic guidelines suggest unenhanced renal lesions < 20 Hounsfield Units (HU) are overwhelmingly benign, requiring no further evaluation. We evaluate our experience with papillary renal cell carcinoma (pRCC) presenting with low pre-contrast attenuation and the relationship of attenuation with histologic pRCC subtype.
Materials and methods: We reviewed our institutional kidney cancer database for patients with pT1 or pT2 pRCC between 2003-2017. Tumors were categorized by papillary subtype by expert uropathologists. Preoperative CT images were analyzed at six regional tumor locations. Low, presumably benign, unenhanced median attenuation was defined as ≤ 20 HU. We calculated the… More >

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ARTICLE

Kassem Faraj¹, Yu-Hui H. Chang², Kyle M. Rose¹, Elizabeth B. Habermann³, David A. Etzioni⁴, Gail Blodgett¹, Erik P. Castle¹, Mitchell R. Humphreys¹, Mark D. Tyson II¹
Canadian Journal of Urology, Vol.26, No.5, pp. 9922-9930, 2019
Abstract Introduction: Mitomycin-C (MMC) and thiotepa are intravesical agents effective in reducing the recurrence of low-grade noninvasive bladder cancer when instilled perioperatively. No studies have compared these agents as a single-dose perioperative instillation. This study tests whether there is a difference in recurrence-free survival in patients with low-grade noninvasive bladder cancer who received intravesical MMC versus thiotepa.
Materials and methods: A retrospective review was performed of patients who underwent cystoscopic excision of a bladder mass identified as a small, low-grade, treatment-naïve, noninvasive, wild-type urothelial carcinoma of the bladder and who received either intravesical thiotepa (30 mg/15 cc) or… More >

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ARTICLE

Kristen E. Gurtner¹, Danica N. May¹, Jay D. Raman², Kathleen Lata-Arias¹, Daniel J. Canter¹
Canadian Journal of Urology, Vol.26, No.5, pp. 9931-9937, 2019
Abstract Introduction: There has been growing use of adrenalectomy as a potentially curative treatment option for patients with oligometastatic disease to the adrenal gland. We sought to compare the perioperative outcomes of patients undergoing isolated adrenalectomy in the setting of disseminated cancer using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database. Furthermore, we examined the impact of performing surgical sub-specialty on outcomes.
Materials and methods: Data from the ACS-NSQIP database was obtained for patients between 2011 and 2016 who underwent adrenalectomy. Patients were stratified by the presence or absence of disseminated cancer. Univariate and… More >

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ARTICLE

Facundo Davaro¹, Allison May¹, Coleman McFerrin², Syed J. Raza¹, Sameer Siddiqui¹, Zachary Hamilton¹
Canadian Journal of Urology, Vol.26, No.5, pp. 9938-9944, 2019
Abstract Introduction: To evaluate the overall survival and pathologic downstaging effect of neoadjuvant chemotherapy for upper tract urothelial cell carcinoma.
Materials and methods: The National Cancer Database (NCDB) was queried for patients with stage II-IV upper tract urothelial cell carcinoma undergoing definitive surgical resection (nephroureterectomy) from 2004-2015. Patients with metastatic disease were excluded. Cohorts were stratified by receipt of neoadjuvant chemotherapy (NAC). Kaplan-Meier analysis and Cox regression were used to evaluate overall survival. Logistic regression was used to predict the odds of pathologic downstaging to non-invasive disease (< pT2). Propensity score matched analysis was performed between groups.
Results: A… More >

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COMMENTARY

Jay D. Raman
Canadian Journal of Urology, Vol.26, No.5, pp. 9945-9945, 2019
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ARTICLE

Stephanie Rodriguez, Andrew D. Sparks, Hanbing Zhou, Richard L. Amdur, Jianqing Lin
Canadian Journal of Urology, Vol.26, No.5, pp. 9946-9951, 2019
Abstract Introduction: To evaluate the impact of prostate cancer screening guidelines on different racial and ethnic populations.
Materials and methods: Data was collected from the 2005-2015 Surveillance, Epidemiology, and End Results (SEER) program. Incidence of prostate cancer diagnosis was categorized and analyzed by stage, race/ethnicity, and age group. Appropriate univariate and multivariable statistical analyses were performed.
Results: The odds of being diagnosed with regional-stage prostate cancer in 2013-2015 were 1.3 times higher for black men, 1.3 times higher for Asian American/Pacific Islander (AAPI) men, and 1.2 times higher for white men when compared to 2005-2008. The odds of being… More >

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RESIDENT’S CORNER

Spyridon P. Basourakos¹, Lucas Dean², James Van Gurp³, Victor Reuter³, Paul Russo²
Canadian Journal of Urology, Vol.26, No.5, pp. 9952-9955, 2019
Abstract Adrenal–renal fusion is an anomaly misclassified as a renal tumor due to the absence of pathognomonic radiographic features. Herein, we report a case of a 61-year-old male who underwent a right radical nephrectomy for a presumed renal malignancy. Pathologic evaluation demonstrated a pheochromocytoma in the context of adrenal–renal fusion. Neoplastic transformation of fused adrenal tissue is rare but not unheard of and is typically adrenal cortical in origin. To our knowledge, this is the first description of a pheochromocytoma originating from an adrenal–renal fusion. The clinical presentation did not raise a high index of suspicion More >

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RESIDENT’S CORNER

Neil J. Kocher¹, Justin Loloi², Joshua Warrick³, Amy S. Burns¹, Ross M. Decter¹
Canadian Journal of Urology, Vol.26, No.5, pp. 9956-9959, 2019
Abstract Neuroendocrine tumors (NETs) are rare tumors with varying clinical presentations. We describe the case of an 11-year-old female presenting with Cushingoid features in the setting of a left-sided flank mass. Her presentation and evaluation suggested a paraneoplastic ectopic ACTH syndrome. She underwent open left radical nephrectomy and final pathology confirming a high-grade NET with nodal metastasis. Although exceedingly rare, ACTH-secreting tumors of the kidney can cause significant morbidity and mortality and so we recommend it be included in the differential diagnosis of pediatric renal masses. More >

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RESIDENT’S CORNER

Katherine Smentkowski, Douglas Kelly
Canadian Journal of Urology, Vol.26, No.5, pp. 9960-9962, 2019
Abstract Epithelioid renal angiomyolipoma is a rare malignant variant of angiomyolipoma (AML); the latter being a well-characterized, benign kidney tumor derived from various connective tissue elements. In this case report, we describe a patient with an epithelioid AML and renal vein thrombus. More >

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HOW I DO IT

Kyle W. Law¹, Dean S. Elterman², Hannes Cash³, Enrique Rijo⁴, Bilal Chughtai⁵, Vincent Misrai⁶, Kevin C. Zorn¹
Canadian Journal of Urology, Vol.26, No.5, pp. 9963-9972, 2019
Abstract For men experiencing lower urinary tract symptoms (LUTS) refractory to medical therapy, there have been numerous developments in the treatment options offered for benign prostatic hyperplasia (BPH) in the recent years. Transurethral resection of the prostate (TURP) has remained the reference standard for men with prostates sized 30 cc-80 cc, while open prostatectomy is universally guidelines-recommended in the absence of enucleation, for men with prostates larger than 80 cc-100 cc. While these techniques are effective, they have the potential for bleeding complications requiring transfusions, electrolyte abnormalities such as TURP syndrome, and often require prolonged hospitalization.… More >

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ABSTRACT

Canadian Journal of Urology, Vol.26, No.5, pp. 9973-10005, 2019
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