Open Access

EDITORIAL

Gabriel P. Haas
Canadian Journal of Urology, Vol.15, No.5, pp. 4229-4229, 2008
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LEGENDS IN UROLOGY

Patrick C. Walsh
Canadian Journal of Urology, Vol.15, No.5, pp. 4230-4232, 2008
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ARTICLE

Andrew J. Macnab, Lynn Stothers
Canadian Journal of Urology, Vol.15, No.5, pp. 4233-4240, 2008
Abstract Introduction: Near infrared spectroscopy (NIRS) is an established technology using photons of light in the near infrared spectrum to monitor changes in tissue of naturally occurring chromophores, including oxygenated and deoxygenated hemoglobin. Technology and methodology have been validated for measurement of a range of physiologic parameters. NIRS has been applied successfully in urology research; however current instruments are designed principally for brain and muscle study.
Objective: To describe development of a NIRS instrument specifically designed for monitoring changes in chromophore concentration in the bladder detrusor in real time, to facilitate research to establish the role of this… More >

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ARTICLE

Andrew J. Macnab, Lynn Stothers
Canadian Journal of Urology, Vol.15, No.5, pp. 4241-4248, 2008
Abstract Introduction: Near infrared spectroscopy (NIRS) is a non-invasive optical technique able to monitor changes in the concentration of oxygenated and deoxygenated hemoglobin in the bladder detrusor during bladder filling and emptying.
Objective: To evaluate the ability of a new NIRS instrument and algorithm to classify male patients with LUTS as obstructed or unobstructed based on comparison with classification via conventional invasive urodynamics (UDS).
Method: Male patients with LUTS were recruited and underwent uroflow and urodynamic pressure flow studies with simultaneous transcutaneous NIRS monitoring following measurement of post residual volume (PVR) via ultrasound. Data analysis first classified each subject… More >

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ARTICLE

Christopher J. DiBlasio¹, Jessica Hammett¹, John B. Malcolm¹, Beth A. Judge², Jamie H. Womack², Matthew C. Kincade¹, Mitchell L. Ogles¹, John M. Mancini¹, Anthony L. Patterson¹, Robert W. Wake¹, Ithaar H. Derweesh¹
Canadian Journal of Urology, Vol.15, No.5, pp. 4249-4256, 2008
Abstract Objective: Androgen deprivation therapy (ADT) remains a widely utilized modality for treatment of localized and advanced prostate cancer. While ADT-induced alterations in testosterone have demonstrated impacts on quality of life, the effects on mental health remain ill-defined. We investigated the prevalence of de novo psychiatric illness and predictive factors following ADT induction for prostate cancer.
Materials and methods: We retrospectively reviewed patients receiving ADT for prostate cancer at our institution between 1/1989-7/2005, excluding men receiving only neoadjuvant ADT. Variables included age, race, body mass index, prostate-specific antigen (PSA), Gleason sum, clinical stage, ADT type (medical/surgical) and schedule… More >

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EDITORIAL COMMENT

Alvaro Morales
Canadian Journal of Urology, Vol.15, No.5, pp. 4256-4256, 2008
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ARTICLE

Kaili Mao¹, Cécile Badoual², Philippe Camparo³, Nicolas Barry Delongchamps¹, Annick Vieillefond⁴, Anh-Tuan Dinh-Xuan⁵, Michaël Peyromaure¹
Canadian Journal of Urology, Vol.15, No.5, pp. 4257-4262, 2008
Abstract Objectives: To study the prognostic value of vascular endothelial growth factor (VEGF)-A and its receptor VEGFR-1 in localized prostate cancer.
Methods: One hundred patients undergoing radical prostatectomy (RP) for clinically localized prostate cancer were prospectively included. Plasma levels of VEGF-A were measured preoperatively. After intervention, tissue microarrays were built from the RP specimens. VEGF-A and VEGFR-1 expressions in prostate cancer tissue were determined using immunochemistry. Then the associations between plasma levels of VEGF-A, VEGF-A and VEGFR-1 expressions in prostate cancer tissue, and the outcome of patients were analyzed.
Results: After a median follow-up of 22 months, 14 patients More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Jamil Rehman¹, Khurshid Guru², Bilal Chughtai³, Ridwan Shabsigh⁴, David Samadi⁵
Canadian Journal of Urology, Vol.15, No.5, pp. 4263-4265, 2008
Abstract Purpose: We present our initial experience with performing robotic-assisted prostatectomies in men with a 3-piece inflatable penile prosthesis with a pelvic reservoir.
Material and methods: Four patients underwent transperitoneal robotic-assisted radical prostatectomies with a penile prosthetic implant in place. The reservoir was left inflated for easy identification. A flaccid reservoir may be more difficult to identify, and be prone to damage. The reservoir was left attached to the abdominal wall. Dissection was performed outside the fibrous capsule of the reservoir. The tissue around the capsule of the reservoir peeled off without difficulty. Cutting current close to the… More >

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CASE REPORT

Imre Romics¹, Eszter Székely², Attila Szendröi¹
Canadian Journal of Urology, Vol.15, No.5, pp. 4266-4268, 2008
Abstract Introduction: Signet-ring cell carcinoma of the urinary bladder can be primary — arising from the bladder wall or urachus remnants — or metastatic from tumors originating in the stomach, colon, or breast. Saphir first described primary signet-ring cell cancer of the urinary bladder in 1955. Less than 100 cases have been reported in the literature since then.
Case report: We report a case of a 45-year-old woman who was admitted with gross hematuria. Cystoscopy revealed a necrotic tumor on the left bladder wall. A transurethral biopsy showed signet-ring cell carcinoma. The bladder tumor was diagnosed as the More >

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CASE REPORT

Pankaj P. Dangle, Wenle Paul Wang, Kamal S. Pohar
Canadian Journal of Urology, Vol.15, No.5, pp. 4269-4272, 2008
Abstract Intravesical instillation of mitomycin C is a routine practice for treatment of superfi cial transitional cell carcinoma of bladder. Despite usual precautions serious side effects like fi stulation can occur with diverse presentation as illustrated by this report. The pathology demonstrates a dense necrotic and massive infl ammatory reaction in the peri vesical tissue following the extravasation of an intravesically administered chemotherapeutic agent. The severe infl ammatory tissue response and the necrotic effect associated with the extravasated chemotherapeutic agent could potentially lead to local sepsis with a subsequent fi stula formation. More >

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RESIDENT’S CORNER

Lei Chu, Marc C. Smaldone, Ronald M. Benoit
Canadian Journal of Urology, Vol.15, No.5, pp. 4273-4275, 2008
Abstract Although rarely used today for supravesical urinary diversion, ureterosigmoidostomy was commonly utilized in patients with bladder exstrophy. We report an unusual case of iliopsoas abscess developing 30 years after an ipsilateral nephrectomy in a patient with bladder exstrophy who had undergone ureterosigmoidostomy for urinary diversion more than 50 years prior. The etiology appeared to be persistent ureteral refl ux and fi stulization from a patent ureterosigmoidostomy stump. After percutaneous drainage of the abscess and intravenous antibiotic therapy, the patient was managed with complete excision of the ureterosigmoid anastomoses and creation of an ileal conduit urinary More >

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RESIDENT’S CORNER

Elizabeth T. Brown¹, Adam E. Perlmutter¹, Brock Oliverio², H. James Williams², Stanley Zaslau¹
Canadian Journal of Urology, Vol.15, No.5, pp. 4276-4278, 2008
Abstract The majority of patients with chromophobe renal cell carcinoma (CRCC) are determined to be asymptomatic, with a small minority of patients having the classic triad of fl ank pain, hematuria, and abdominal mass. This case report describes a 56-year-old man fi rst seen with hemorrhagic shock from retroperitoneal bleeding attributable to a large renal mass. An emergent exploratory laparotomy and radical nephrectomy were performed and the patient has since remained disease free at 3 year follow-up. More >

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CLINICAL TRIALS

Richard W. Casey¹, Jack Barkin²
Canadian Journal of Urology, Vol.15, No.5, pp. 4279-4283, 2008
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CLINICAL TRIALS

Eric Winquist, Mary J. Mackenzie, George Rodrigues
Canadian Journal of Urology, Vol.15, No.5, pp. 4284-4290, 2008
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ABSTRACT

Canadian Journal of Urology, Vol.15, No.5, pp. 4291-4344, 2008
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