Open Access

EDITORIAL

Xingkang Jiang^*, Jing Tian, Yong Xu
Canadian Journal of Urology, Vol.32, No.6, pp. 539-540, 2025, DOI:10.32604/cju.2025.073363 - 30 December 2025
Abstract This article has no abstract. More >

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LEGENDS IN UROLOGY

Mahesh R. Desai
Canadian Journal of Urology, Vol.32, No.6, pp. 541-544, 2025, DOI:10.32604/cju.2025.077490 - 30 December 2025
Abstract This article has no abstract. More >

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89

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MINI REVIEW

Ankith P. Maremanda^*, Anna Faris, Benjamin N. Breyer
Canadian Journal of Urology, Vol.32, No.6, pp. 545-550, 2025, DOI:10.32604/cju.2025.064433 - 30 December 2025
Abstract We describe the history of Patient-Reported Outcome Measures (PROMs) in medicine, with a focus on the development and use of the International Index of Erectile Function (IIEF) in urologic practice. PROMs emerged in the 1970s with tools like the Sickness Impact Profile, designed to capture patients’ perspectives on how disease affects daily life. In the 1990s, PROMs entered urology with the creation of the International Prostate Symptom Score (IPSS) and the IIEF, developed in 1992 and 1997, respectively. As organizations such as the National Institutes of Health began prioritizing PROMs for evaluating sexual function, the More >

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REVIEW

John Hordines¹, Shirley Ge², Dima Raskolnikov¹, Alexander C. Small¹, Kara L. Watts^1,*
Canadian Journal of Urology, Vol.32, No.6, pp. 551-560, 2025, DOI:10.32604/cju.2025.065988 - 30 December 2025
Abstract Background: The healthcare industry contributes nearly 5% of worldwide carbon emissions. In an effort to mitigate this impact, urology practices can take steps to reduce their carbon footprints. We conducted a systematic review which aimed to summarise the current literature on the environmental impact of urologic-related care. Methods: A systematic literature review evaluating the impact of urologic procedures, telehealth and conferences/interviews was conducted on PubMed and Cochrane databases using a Boolean search strategy and the following search terms: urology, planetary health, environmental impact, carbon emissions, carbon footprint, and waste. Full-text articles published in English were… More >

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552

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ARTICLE

Taras Shatylko^1,*, Ruslan Safiullin¹, Safar Gamidov^1,2, Tatiana Ivanets¹, Ramazan Mammaev², Kanan Guluzade², Ilia Rodin³, Gennadiy Sukhikh¹
Canadian Journal of Urology, Vol.32, No.6, pp. 561-568, 2025, DOI:10.32604/cju.2025.064572 - 30 December 2025
Abstract Background: Some patients with prostate cancer have elevated gonadotropin levels. It is unknown, however, whether this condition directly influences carcinogenesis in the prostate. It is also unknown whether any specific hormone levels are useful to predict aggressive disease. The potential role of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in prostate physiology is widely discussed. The study aimed to evaluate whether patients with this endocrine pattern have different outcomes following radical prostatectomy. Methods: This was a prospective cohort study of consecutive patients undergoing robot-assisted radical prostatectomy at the Andrology and Urology Department, National Medical Research… More >

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ARTICLE

Şeref Barbaros Arik^1,2,*, İnanç Güvenç^1,2
Canadian Journal of Urology, Vol.32, No.6, pp. 569-578, 2025, DOI:10.32604/cju.2025.068094 - 30 December 2025
Abstract Objectives: Differentiating benign from malignant testicular lesions is essential to avoid unnecessary surgery and ensure timely intervention. While conventional ultrasound remains the first-line imaging method, elastography and MRI provide additional functional and structural information. This study assesses the diagnostic utility of testicular elastography and magnetic resonance imaging (MRI) in differentiating benign and malignant testicular lesions. Methods: Patients with sonographically detected testicular masses were retrospectively evaluated using elastography, scrotal MRI, and tumor markers. Quantitative and qualitative imaging findings, lesion size, and laboratory values were recorded. Statistical analyses included Fisher’s exact test, logistic regression, Receiver operating characteristic… More >

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394

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ARTICLE

Song Xu^1,2,3,4,5,*, Mengxin Lu^1,2,3,4,5, Zhonghua Yang^1,2,3,4,5, Hang Zheng^1,2,3,4,5
Canadian Journal of Urology, Vol.32, No.6, pp. 579-588, 2025, DOI:10.32604/cju.2025.063069 - 30 December 2025
Abstract Background: Many studies have evaluated the performance of fluorescence in situ hybridization (FISH) in detecting urothelial carcinoma, while few of them compared it in detecting bladder cancer (BC) vs. upper tract urothelial carcinoma (UTUC). This study aimed to determine and compare the FISH performance in detecting BC and UTUC. Methods: Data of patients with suspected urothelial carcinoma (UC) who accepted FISH from January 2021 to April 2023 were retrieved. The sensitivity and specificity of FISH in detecting BC and UTUC were determined and compared. Results: A total of 145 BC, 62 UTUC, and 170 non-UC patients were… More >

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816

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257

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ARTICLE

Joon Yau Leong¹, Tyler Gaines², Zachary J. Prebay¹, David Ebbott¹, Paul H. Chung^1,*
Canadian Journal of Urology, Vol.32, No.6, pp. 589-595, 2025, DOI:10.32604/cju.2025.064125 - 30 December 2025
Abstract Introduction: Despite the diagnostic value of intracavernosal injections (ICI) and penile Doppler ultrasound (PDUS), there remain barriers to widespread clinical adaptation of these methods. The study aimed to evaluate the practice patterns of utilization of ICI and PDUS in the assessment of erectile dysfunction (ED) and Peyronie’s disease (PD). Methods: Using the TriNetX database (Cambridge, MA, USA), adult (≥18 years) male patients with a diagnosis of ED on oral phosphodiesterase-5 (PDE5) inhibitors were identified. Current Procedural Terminology codes were utilized to identify patients who underwent further evaluation with ICI or PDUS, as well as penile… More >

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800

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243

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ARTICLE

Hasan Jhaveri^*, Mariela Martinez-Rivera, Brent Nose, Jordan Foreman, Aaron C. Lentz
Canadian Journal of Urology, Vol.32, No.6, pp. 597-603, 2025, DOI:10.32604/cju.2025.068095 - 30 December 2025
Abstract Objectives: There is limited in vivo data on the maximum safe instrument size that can be passed through an artificial urinary sphincter (AUS) cuff. While 21 French instruments are generally safe with the commonly used 4.5 cm cuff, larger instruments or smaller cuffs may require unbuckling to avoid urethral erosion. This study aimed to identify if artificial urinary sphincter cuff ‘unbuckling’ affects device longevity and risk of erosion. Methods: A retrospective study of patients at a quaternary health system who underwent unbuckling was conducted. Using the Epic Clarity database and Duke Enterprise Data Unified Content Explorer… More >

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756

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252

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ARTICLE

Abdul Baseet Arham¹, John M. Rieth², Michael A. O’Donnell^3,*
Canadian Journal of Urology, Vol.32, No.6, pp. 605-620, 2025, DOI:10.32604/cju.2025.063632 - 30 December 2025
Abstract Background: Genitourinary (GU) sarcomas are rare soft tissue malignancies, comprising around 2% of all GU cancers. Due to their rarity, limited data exist on optimal management and long-term outcomes. This study presents a 25-year single-institution experience, evaluating clinical presentation, treatment strategies, and survival outcomes, aims to identify trends over time and potential predictors of prognosis. Methods: A retrospective review was conducted of patients aged ≥18 years diagnosed with GU sarcomas at the University of Iowa Hospitals and Clinics (1998–2023). Data on tumor subtype, staging, histopathology, treatment modalities, and survival outcomes were analyzed. Kaplan-Meier analysis estimated… More >

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222

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ARTICLE

Luke Patrick O’Connor¹, Alexander Jordan Henry², Wendy Michelle Novicoff³, Marwan Ali², Adam Seth Baumgarten⁴, Nicolas Martin Ortiz^2,*
Canadian Journal of Urology, Vol.32, No.6, pp. 621-626, 2025, DOI:10.32604/cju.2025.065217 - 30 December 2025
Abstract Background: Postoperative pain management after penile prosthesis (PP) has traditionally required opioid medication. Recently, urologic prosthetic surgeons have sought to establish opioid-free protocols (OFP) and/or opioid-reduced protocols (ORP) for PP postoperative pain management. We sought to investigate the adoption patterns of OFP/ORP among surgeons who perform PP surgery and identify barriers to implementation. Methods: A 13-question confidential survey was sent to members of the Sexual Medicine Society of North America (SMSNA) and the Society of Urologic Prosthetic Surgeons (SUPS) via email. The survey was administered via Qualtrics. A t-test was used to analyze survey responses. Results:… More >

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756

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254

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ARTICLE

Anushka Ghosh, Maria J. D’Amico, Yash B. Shah, Whitney R. Smith, Mihir S. Shah, Costas D. Lallas, Alana M. Murphy^*
Canadian Journal of Urology, Vol.32, No.6, pp. 627-632, 2025, DOI:10.32604/cju.2025.067575 - 30 December 2025
Abstract Background: Genitourinary syndrome of menopause (GSM) is a highly prevalent, underdiagnosed condition that can significantly impair quality of life (QoL). This study evaluates real-world treatment trends for GSM to better understand current management practices and highlight ongoing gaps in care. The background is in a different font than the rest of the abstract. Methods: We queried the TriNetX database for patients with a diagnosis of postmenopausal atrophic vaginitis (ICD N95.2) and treatment information from 2004–2024. A combination of RxNorm and International Classification of Diseases-10 (ICD) codes was used to classify disease and treatment type, including… More >

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660

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281

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ARTICLE

Maxwell Sandberg^1,*, Mark Xu¹, Randall Bissette¹, Jacob Malakismail², Niara East³, Robenson Nguyen⁴, Jackson Nowatzke¹, Robert Stratta⁵, Dean Assimos^1,6, Colin Kleinguetl¹
Canadian Journal of Urology, Vol.32, No.6, pp. 633-641, 2025, DOI:10.32604/cju.2025.069091 - 30 December 2025
Abstract Objectives: Donor-gifted nephrolithiasis—the presence of a stone in a donor kidney at the time of transplantation—is rare. Research is limited, and no consensus high-quality evidence guidelines exist, leaving selection criteria and management to individual provider discretion. We aimed to estimate the frequency and analyze patient and graft outcomes of deceased donor (DD) transplant recipients with stones in their kidneys at Wake Forest Baptist Medical Center. Methods: All DD renal transplants or patients receiving most of their care postoperatively after DD renal transplantation at our institution from 1979 to 2025 were reviewed. Stones were considered donor-gifted… More >

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735

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ARTICLE

Charles H. Schlaepfer¹, Zubin Shetty¹, Vignesh T. Packiam¹, Chad R. Tracy¹, Elizabeth B. Takacs¹, Ruslan Korets², Ryan L. Steinberg^1,*
Canadian Journal of Urology, Vol.32, No.6, pp. 643-649, 2025, DOI:10.32604/cju.2025.064818 - 30 December 2025
Abstract Introduction: Point-of-care ultrasound (POCUS) is a valuable tool for clinicians, but little data exists regarding the perceptions of ideal POCUS utilization, as compared to actual use, amongst urologists. We aim to assess how perceptions align or diverge with actual practice. Methods: An institutional review board (IRB)-approved survey was developed and disseminated by email to 6 of 8 American Urologic Association Sections, program directors via the Society of Academic Urologists, and to 2 residency programs. The primary outcome was to assess differences in current and perceived optimal use. Data was collected via the University of Iowa… More >

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805

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308

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HOW I DO IT

Yoav Avidor^#,*, Ghalib Lidawi^#, Muhammad Majdoub, Mohsin Asali, Ronen Rub
Canadian Journal of Urology, Vol.32, No.6, pp. 651-657, 2025, DOI:10.32604/cju.2025.064383 - 30 December 2025
Abstract In this paper we describe a surgical technique for achieving safe ureteral stent placement in cases of severe obstruction. Although retrograde endoscopic stenting is often the preferred method for ureteral drainage, the existing literature offers limited insight into innovative surgical methods made possible by recent technological advancements. In this report, we present a method that employs a ureteral dilator as an anchor to facilitate precise and effective stent insertion. The technique involves positioning a ureteral dilator in close contact with the tip of the obstructing stone. In this position, the dilator not only functions to More >

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863

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COMMUNICATION

Vinay Durbhakula^1,*, Ziv Savin¹, Einat Savin-Shalom², Stephanie L. Gold², Kavita Gupta¹, Eve Frangopoulos¹, Blair Gallante¹, William M. Atallah¹, Mantu Gupta¹
Canadian Journal of Urology, Vol.32, No.6, pp. 659-668, 2025, DOI:10.32604/cju.2025.067614 - 30 December 2025
Abstract Background: A well-established correlation exists between Inflammatory Bowel Disease (IBD) and urolithiasis. However, the influence of surgical history on the severity of urolithiasis in IBD patients remains underexplored. This study aims to investigate the association between gastrointestinal (GI) bowel resection and urolithiasis severity in patients with IBD. Methods: This retrospective cohort study analyzed 42 patients diagnosed with both IBD and urolithiasis between 2016 and 2024. Patients were categorized based on their history of bowel resection. Primary outcomes included maximal stone burden, need for urolithiasis surgery, and stone recurrence. Secondary outcomes were stone-related clinical events, multiple… More >

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893

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CASE REPORT

William Daly^*, Daniel Pelzman, P. Dafe Ogagan, Stephen V. Jackman
Canadian Journal of Urology, Vol.32, No.6, pp. 669-672, 2025, DOI:10.32604/cju.2025.063778 - 30 December 2025
Abstract Background: Minor bleeding after prostate biopsy is a relatively common complication, but clinically significant hemorrhage happens rarely. Management of prostatic artery pseudoaneurysm has not been described in the literature. Case Description: In this case, an 84-year-old man presented after prostate biopsy with rectal bleeding and required a massive transfusion. Ultimately, he was found to have a prostatic artery pseudoaneurysm, which to our knowledge is heretofore undescribed after prostate biopsy. Bleeding ultimately stopped spontaneously as the patient deferred angioembolization. He had not recurrent bleeding on follow up but is still deciding on treatment course for newly diagnosed More >

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538

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169

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CASE REPORT

Jordan L. Mendelson^1,*, Jordan Kassab¹, Phillip Westbrook¹, Katie Yang², Anthony Corcoran¹
Canadian Journal of Urology, Vol.32, No.6, pp. 673-676, 2025, DOI:10.32604/cju.2025.063770 - 30 December 2025
Abstract Stereotactic body radiotherapy (SBRT) for prostate cancer is a generally well-tolerated treatment but can rarely lead to complications such as fistula formation. We report a 69-year-old male on maintenance ibrutinib for chronic lymphocytic leukemia who developed a fistula between his bladder and vas deferens in the setting of ascending scrotal infection. Despite his prior history of SBRT, the fistula was successfully treated with minimally invasive measures. A combination of abscess debridement, urinary diversion, and broad-spectrum antibiotics helped to achieve fistula resolution. The unique presentation described herein highlights the importance of early aggressive intervention for source More >

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1101

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309

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CASE REPORT

Siddharta Saxena, Vikas Kumar Panwar,^*, Ankur Mittal, Mohammed Taher Mujahid, Mehul Agarwal, Nalin Kumar Srivastav
Canadian Journal of Urology, Vol.32, No.6, pp. 677-683, 2025, DOI:10.32604/cju.2025.063597 - 30 December 2025
Abstract Background: Injuries to the penis resulting from self-inflicted strangulation with various objects are uncommon, yet these injuries are more frequently observed in young adults. Medical literature has identified items such as hair, thread, rubber bands, metallic rings, and vacuum erection devices as tools used for this purpose. These constrictive items impede venous return from the penis, potentially leading to severe complications such as ischemia or necrosis. This case series aims to analyse the clinical presentation, management strategies, and psychological dimensions of self-inflicted penile strangulation through a case series. Case Presentation: We conducted a retrospective analysis of… More >

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1343

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CASE REPORT

Harshdeep Singh^*, Pawan Vasudeva, Thiyagarajan Kalaiselvi Aravind
Canadian Journal of Urology, Vol.32, No.6, pp. 685-689, 2025, DOI:10.32604/cju.2025.064435 - 30 December 2025
Abstract Background: Brunn’s cyst is a seldom encountered etiology in a wide spectrum of causative pathologies producing lower urinary tract symptoms (LUTS) in a young male, causing voiding symptoms, with prompt symptom resolution following surgical management. A diagnostic dilemma may arise, as other bladder neck cystic lesions differ in anatomical location, etiology, and the nature of associated LUTS. Case Description: We report a middle-aged male patient with Brunn’s cyst with a brief description of our management strategies and a review of available literature. Conclusions: Brunn’s cyst is a rare but treatable cause of bladder outlet obstruction in More >

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