Open Access

EDITORIAL

Gabriel P. Haas
Canadian Journal of Urology, Vol.16, No.5, pp. 4801-4801, 2009
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LEGENDS IN UROLOGY

John M. Barry
Canadian Journal of Urology, Vol.16, No.5, pp. 4802-4805, 2009
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ARTICLE

Oliver Sartor¹, Leonard G. Gomella², Paul Gagnier³, Karen Melich³, Rebekkah Dann³
Canadian Journal of Urology, Vol.16, No.5, pp. 4806-4812, 2009
Abstract Introduction: Bicalutamide blocks androgen action in men with prostate cancer but has low affinity for the androgen receptor compared to dihydrotestosterone (DHT). Dutasteride, a dual 5α-reductase inhibitor (5ARI), blocks the conversion of testosterone to DHT, reduces tumor volume and improves PSA in prostate cancer. Bicalutamide should be a more effective antiandrogen if it competes against intraprostatic testosterone, rather than DHT, for the androgen receptor. The Therapy Assessed by Rising PSA (TARP) study investigates dutasteride in combination with bicalutamide to prevent or delay disease progression in patients with castrate-refractory prostate cancer (CRPC) after initial androgen deprivation therapy.
Patients… More >

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ARTICLE

Nicolas B. Delongchamps¹, Marc Zerbib¹, Arnaud Méjean², Yannick Rouach², Bernard Debré¹, Michaël Peyromaure^1,2
Canadian Journal of Urology, Vol.16, No.5, pp. 4813-4819, 2009
Abstract Introduction: Many studies have analyzed outcomes following salvage radiation therapy (RT) after biochemical recurrence--defined as the presence of detectable serum prostate-specific antigen (PSA)--following radical prostatectomy (RP). However, the management of patients with detectable PSA following RP, which is not specific for tumor recurrence, is a matter of debate. This study aimed to evaluate oncological results of three-dimensional conformal RT (3D-CRT) in patients who had biochemical recurrence.
Materials and methods: The study included patients who underwent RP, who had a postoperative PSA level--determined between 2 and 4 months after surgery--that was greater than 0.1 ng/ml, and who subsequently… More >

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ARTICLE

Anthony T. Corcoran, Matthew H. Hayn, Erin P. Gibbons, Ryan Mori, Ronald Hrebinko, Benjamin J. Davies
Canadian Journal of Urology, Vol.16, No.5, pp. 4820-4825, 2009
Abstract Introduction: Partial nephrectomy for the management of small renal masses has become a well accepted technique. Contemporary series have shown its safety and efficacy in well selected patients. We present our experience of partial nephrectomies exclusively without hilar control or parenchymal cooling stratified into imperative and elective patients.
Methods: We retrospectively reviewed our experience in 124 patients who underwent partial nephrectomy between December 1995 and September 2003. Patients were followed with regular radiographic and laboratory studies at 6 months postsurgery and then annually. Renal function was followed by serum creatinine.
Results: Of the 124 patients, 105 were performed… More >

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ARTICLE

Danny M. Rabah, Ayman A. Adwan, Mohamed A. Seida
Canadian Journal of Urology, Vol.16, No.5, pp. 4826-4830, 2009
Abstract Background and objectives: Hydrocele caused by the division of lymphatic vessels during varicocelectomy is a common complication. Preservation of these lymphatics is the aim of many studies. We evaluated patient outcomes after laparoscopic varicocelectomy that involved intratunical methylene blue dye injection just prior to the procedure.
Materials and methods: This prospective study included all adult patients (over age 14 years) with clinically palpable varicocele who presented to our clinic between December 2005 and July 2007. Prior to laparoscopic surgery, methylene blue dye was injected in the intratunical space between the tunica albuginea and the tunica vaginalis. Laparoscopic intraperitoneal… More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Curtis Clark¹, Jason Bylund¹, Matthew Paszek¹, Chad LaGrange², Vernon M. Pais Jr³
Canadian Journal of Urology, Vol.16, No.5, pp. 4831-4835, 2009
Abstract Objectives and background: We describe a novel approach for removal of a retained, heavily encrusted ureteral stent via combined laparoscopic cystolithotomy and pyelolithotomy. Due to noncompliance, our patient with a history of nephrolithiasis returned with large proximal and distal stones 2.5 years after placement of a left ureteral stent.
Methods: Laparoscopy was performed using three 12 mm ports and two 5 mm ports. The bladder was opened in the midline and the stent divided at the ureteral orifice. The bladder stone (4.7 cm x 4 cm) was placed in a retrieval bag and the cystotomy closed with… More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

L. Spencer Krane, Christel Wambi, Akshay Bhandari, Hans J. Stricker
Canadian Journal of Urology, Vol.16, No.5, pp. 4836-4840, 2009
Abstract Introduction: Posterior urethrovesical anastomotic support has been reported to improve early return of urinary continence following radical prostatectomy. We adapted this technique to evaluate enhancement of early urinary control in patients undergoing robotic radical prostatectomy.
Materials and methods: Forty-two consecutive men undergoing radical prostatectomy by a single surgeon between September and December 2007 received a posterior urethrovesical supporting stitch prior to the standard urethrovesical anastomosis (group 1). Operative data, postoperative complications, and follow up data were compared with those of the 42 consecutive men who underwent robotic radical prostatectomy by the same surgeon between March and August… More >

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EDITORIAL COMMENT

Moinzadeh Alireza
Canadian Journal of Urology, Vol.16, No.5, pp. 4841-4841, 2009
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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Jennifer Yates, George Haleblian, Barry Stein, Joseph Renzulli, Gyan Pareek
Canadian Journal of Urology, Vol.16, No.5, pp. 4842-4846, 2009
Abstract Introduction: Open pelvic lymph node dissection (PLND) remains the gold standard in patients with intermediate and high-risk prostate cancer undergoing radical retropubic prostatectomy (RRP). Recently, our institution has adopted robotic assistance for performing radical prostatectomy. We sought to determine whether robot-assisted laparoscopic PLND yields comparable numbers of lymph nodes compared to open PLND.
Methods: The medical records of patients undergoing open or robot-assisted laparoscopic radical prostatectomy (RALRP) with concurrent pelvic lymph node dissection (PLND) between 2003 and 2008 were reviewed. Demographic factors including age, PSA, and Gleason score were recorded. Pathology reports were reviewed to determine the… More >

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EDITORIAL COMMENT

Riccardo Autorino, Robert J. Stein
Canadian Journal of Urology, Vol.16, No.5, pp. 4846-4846, 2009
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CASE REPORT

Huseyin Kadikoy¹, Waqar M. Haque¹, Veli K. Topkara¹, Adam I. Frome¹, Teresa G. Hayes^1,2
Canadian Journal of Urology, Vol.16, No.5, pp. 4847-4849, 2009
Abstract Sarcomas make up 1%-2% of all malignant renal tumors in adults, and the incidence increases with advancing age. Renal sarcomas are less common, but more lethal than sarcomas of any other genitourinary site. The common clinical presentation of renal sarcomas in adults include a palpable mass, abdominal or fl ank pain, and hematuria, similar to those seen with large, rapidly growing renal cell carcinomas. Usually, radical nephrectomy remains the treatment of choice for these tumors, which exhibit an aggressive biological behavior and an unfavorable prognosis. We describe an unusual case of bilateral renal leiomyosarcoma in More >

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CASE REPORT

Kien T. Mai, Bich Nguyen
Canadian Journal of Urology, Vol.16, No.5, pp. 4850-4853, 2009
Abstract Urothelial carcinoma (UC) and prostatic adenocarcinoma (PAC) commonly occur in elderly patients and share common carcinogenic factors that could be identifi ed in the urine. The presence of one tumor is known to be associated with an increased incidence of the other. Simultaneous occurrence of PAC and UC in the prostate is not uncommon; however, urinary bladder location of both lesions has not yet been reported. Furthermore, invasion into the urinary bladder wall by a PAC can also pose a diagnostic challenge with UC and other primary urinary bladder tumors.
We report three patients presenting… More >

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CASE REPORT

Antonios Makris¹, Ruth Tabaza¹, Bernhard Brehmer¹, Katharina Lindemann-Docter², Joachim Wildberger³, Gerhard Jakse¹
Canadian Journal of Urology, Vol.16, No.5, pp. 4854-4856, 2009
Abstract A solitary fibrous tumor of the kidney is a rare neoplasm that was often misdiagnosed as hemangiopericytoma until recently. We report a case of a 35-year-old male patient with a solid, 7 cm tumor located centrally in a solitary right kidney. The patient underwent successful bench surgery and autotransplantation. More >

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CASE REPORT

Seiichi Kato¹, Kensaku Seike¹, Takako Masue², Naoki Yamamoto³, Shinichi Maeda¹
Canadian Journal of Urology, Vol.16, No.5, pp. 4857-4859, 2009
Abstract We report a case of renal epithelioid angiomyolipoma that arose in association with a classic angiomyolipoma in a 54-year-old Japanese man without tuberous sclerosis. Histologically, the tumor was composed of polygonal cells exhibiting diffuse hemorrhage, multifocal necroses, and vascular invasion. Immunohistochemical staining was positive for melanoma specifi c antibody and focally positive for smooth muscle actin. On the basis of a review of the literature, we suggest that large epithelioid angiomyolipoma may have malignant potential and therefore requires close follow up. More >

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CASE REPORT

Altug Tuncel¹, Tezcan Sezgin¹, Nuket Uzum², Omur Ataoglu³, Ali Atan¹
Canadian Journal of Urology, Vol.16, No.5, pp. 4860-4862, 2009
Abstract A 53-year-old man presented with weakness, loss of weight, pain in upper and lower extremities, and back pain. He had an intermittent abscess like discharge from a left hemi scrotal lesion. Thoraco abdomino pelvic computerized tomography revealed diffuse, multiple and hypodense lesions in the liver parenchyma. Bone scan showed multi metastatic disease of the bone. Complete resection of the scrotal lesion was performed. In histopathological examination, apocrine adenocarcinoma was diagnosed. More >

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RESIDENT’S CORNER

Luke T. Lavallée ¹, Greg Trottier ², Greg Bailly ²
Canadian Journal of Urology, Vol.16, No.5, pp. 4863-4865, 2009
Abstract Hemorrhage from an ileal conduit is a rare and potentially life threatening event with only 17 cases reported in the medical literature. We present the unique case of an 83-year-old patient with acute stomal hemorrhage as the fi rst sign of underlying liver disease and portal hypertension. Bleeding was controlled with conservative measures including balloon tamponade, betablockade, octreotide, and suture ligation. Our review of the literature revealed multiple management options for stomal hemorrhage with most authors advocating defi nitive management via portosystemic shunt creation, either surgically, or with transjugular intrahepatic portosystemic shunt (TIPS). In all More >

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RESIDENT’S CORNER

Shahab Hillyer , Frederick A. Gulmi
Canadian Journal of Urology, Vol.16, No.5, pp. 4866-4869, 2009
Abstract Objective: Transitional cell carcinoma of the bladder is commonly treated with intravesical BCG. We report a cutaneous complication of BCG after therapy in 66-year-old male 4 years after initiating treatment.
Materials and methods: A case review including pathological slides, laboratory data, and radiographic findings.
Results: Biopsy findings showed an ill defined granulomatous process with chronic inflammation and necrosis.
Conclusion: The patient was managed on antituberculous therapy for a period of 6 months with resolution of symptoms. More >

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RESIDENT’S CORNER

Jay Heintz , Judd Chason , Andrew Kramer
Canadian Journal of Urology, Vol.16, No.5, pp. 4870-4872, 2009
Abstract Purpose: We present a case of a large, vaginal calculus which eroded into the bladder ultimately causing bilateral ureteral obstruction and acute renal failure.
Materials and methods: A 34-year-old female presented with dysuria and urinary hesitancy. The diagnosis, workup, and treatment are outlined.
Results: Consistent with radiographic findings, the stone was a primary vaginal stone which eroded into the bladder, the nidus of the stone being a vaginal foreign body. This vaginal stone, by eroding into the bladder, caused bilateral ureteral obstruction and renal failure.
Conclusion: A vaginal foreign body can grow so large that it can erode into More >

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CLINICAL TRIALS

Richard W. Casey ¹, Jack Barkin ²
Canadian Journal of Urology, Vol.16, No.5, pp. 4873-4874, 2009
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CLINICAL TRIALS

Eric Winquist , Mary J. Mackenzie , George Rodrigues
Canadian Journal of Urology, Vol.16, No.5, pp. 4875-4881, 2009
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