Open Access

CASE REPORT

Epithelioid angiomyolipoma associated with a classic angiomyolipoma

Seiichi Kato¹, Kensaku Seike¹, Takako Masue², Naoki Yamamoto³, Shinichi Maeda¹

1 Department of Urology, Toyota Memorial Hospital, Toyota, Japan
2 Department of Urology, Gifu University Hospital, Gifu, Japan
3 Department of Primary Care, Shinsei Hospital, Nagano, Japan
Address correspondence to Dr. Naoki Yamamoto, Department of Primary Care, Shinsei Hospital, 851 Obuse, Obuse-chou, Kamitakaigun, Nagano, Japan 381-0295

Canadian Journal of Urology 2009, 16(5), 4857-4859.

Abstract

We report a case of renal epithelioid angiomyolipoma that arose in association with a classic angiomyolipoma in a 54-year-old Japanese man without tuberous sclerosis. Histologically, the tumor was composed of polygonal cells exhibiting diffuse hemorrhage, multifocal necroses, and vascular invasion. Immunohistochemical staining was positive for melanoma specifi c antibody and focally positive for smooth muscle actin. On the basis of a review of the literature, we suggest that large epithelioid angiomyolipoma may have malignant potential and therefore requires close follow up.

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Keywords

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