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EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.18, No.5, pp. 5860-5860, 2011
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LEGENDS IN UROLOGY

Arthur Smith
Canadian Journal of Urology, Vol.18, No.5, pp. 5861-5863, 2011
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BOOK REVIEW

Pamela Ellsworth
Canadian Journal of Urology, Vol.18, No.5, pp. 5864-5864, 2011
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REVIEW

Bob Djavan¹, Kathleen Nelson², Amir Kazzazi¹, Aron Bruhn¹, Helen Sadri¹, Alejandro Gomez-Pinillos³, Anna C. Ferrari³
Canadian Journal of Urology, Vol.18, No.5, pp. 5865-5874, 2011
Abstract Prostate cancer is a complex disease, and treatment selection is informed by numerous variables depending on the stage of disease. Moreover, patient expectations and the impact of treatment-related adverse events may infl uence treatment choices. Available treatment options over the course of the disease have included surgery, radiation therapy, hormonal therapy, immunotherapy, and chemotherapy. This complexity requires an understanding of a wide range of treatment options and the support of a multidisciplinary team that involves urologists, radiation oncologists, diagnostic radiologists, pathologists, and medical oncologists. Collaboration among these physicians allows for a comprehensive treatment strategy that… More >

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REVIEW

Leonard G. Gomella¹, Xiaolong S. Liu¹, Edouard J. Trabulsi¹, Wm. Kevin Kelly², Ronald Myers², Timothy Showalter³, Adam Dicker³, Richard Wender⁴
Canadian Journal of Urology, Vol.18, No.5, pp. 5875-5883, 2011
Abstract Introduction: Prostate cancer presents a global public health dilemma. While screening with prostate specific antigen (PSA) has led to more men diagnosed with prostate cancer than in previous years, the potential for negative effects from over-diagnosis and treatment cannot be ignored.
Materials and methods: We reviewed Medline for recent articles that discuss clinical trials, evidence based recommendations and guidelines from major medical organizations in the United States and worldwide concerning prostate cancer screening.
Results: Results from the European Randomized Screening for Prostate Cancer (ERSPC), the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, and Göteborg Swedish trials… More >

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EDITOR’S NOTE

Leonard G. Gomella
Canadian Journal of Urology, Vol.18, No.5, pp. 5883-5883, 2011
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ARTICLE

Giovanny Vivas-Acevedo¹, Ricardo Lozano-Hernandez¹, Maria I. Camejo²
Canadian Journal of Urology, Vol.18, No.5, pp. 5884-5889, 2011
Abstract Introduction: Varicocele has been associated with decreased semen quality. However, little is known about the effect of varicocele on the function of the accessory sex glands. The purpose of this study was to evaluate the relationship among varicocele, seminal parameters, and biochemical markers of accessory sex glands: neutral alpha-glucosidase (NAG, epididymis), fructose (seminal vesicles), prostatic acid phosphatase (PAP), and zinc (prostate).
Materials and methods: A clinical study was conducted in 190 men with varicocele and 100 normozoospermic men as the control group. Semen analysis, hypo-osmotic swelling test (HOST), polymorphonuclear (PMN) cell count, fructose, zinc, PAP, and NAG… More >

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ARTICLE

Gina M. Badalato, Gregory Hruby, Mani Razmjoo, James M. McKiernan
Canadian Journal of Urology, Vol.18, No.5, pp. 5890-5895, 2011
Abstract Introduction: This study aimed to evaluate cancer-specific outcomes among patients who received perioperative mitomycin C (MMC) prior to induction BCG compared to those who received induction BCG alone.
Materials and methods: Between January 2000 and August 2010, 260 patients were identified who underwent a course of induction BCG with or without concomitant perioperative MMC. Specifically, patients who received 40 mg MMC following transurethral resection of all visible tumors, followed by an induction course of BCG, were compared to a similar cohort receiving induction BCG alone. The primary endpoints were overall survival and recurrence-free survival (RFS).
Results: A total… More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Jay D. Raman^1,3, Benjamin Smith², Jamie Messer¹, Thomas J. Rohner¹, Lewis E. Harpster¹, Carl T. Reese¹
Canadian Journal of Urology, Vol.18, No.5, pp. 5896-5902, 2011
Abstract Introduction: To evaluate preoperative parameters of patients undergoing partial nephrectomy to determine variables that impact selection of operative approach.
Materials and methods: The charts of 229 consecutive patients undergoing partial nephrectomy were reviewed. Clinical data points and associated axial imaging were evaluated to determine factors which contributed to selection of an open (versus laparoscopic) operation.
Results: A total of 140 men and 89 women with a mean age of 57 years, body mass index (BMI) of 31, and glomerular filtration rate (GFR) of 82 mL/min/1.73 m² were included. Twenty-three percent of patients had prior abdominal surgery and 7% had… More >

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MINIMALLY INVASIVE AND ROBOTIC SURGERY

Petar Erdeljan¹, Mrinal Dhar², Geoff Wignall³, Roman Kozak⁴, Stephen E. Pautler^1,5
Canadian Journal of Urology, Vol.18, No.5, pp. 5903-5907, 2011
Abstract Introduction: Cryoablation (CA) and radiofrequency ablation (RFA) are nephron-sparing procedures that destroy renal tissue in situ rather than by surgical removal. Both thermal ablative techniques are recommended for select patients with small renal masses and multiple comorbidities that may preclude major surgery. Unfortunately, the long-term oncologic outcomes of these procedures remain unknown.
Materials and methods: We report oncologic outcomes following CA and RFA in patients with small renal masses from a single institution over a 48-month follow-up period. A total of 30 patients underwent thermal ablation for a small renal mass: 7 received RFA and 23 underwent CA.
… More >

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RESIDENT’S CORNER

Garrett S. Korrect¹, Melissa V. Kesler², Stephen E. Strup¹
Canadian Journal of Urology, Vol.18, No.5, pp. 5908-5910, 2011
Abstract We present a case of pelvic aggressive angiomyxoma presenting as urinary retention in a male. A 46-year-old male presented with urinary retention and was found on computed tomography (CT) scan of the pelvis to have a large pelvic tumor. A transrectal ultrasound guided needle biopsy of the tumor and prostate revealed a myxoid tumor; low volume, low grade prostate cancer was also detected. The patient underwent radical prostatectomy and excision of the pelvic tumor which was diagnosed as aggressive angiomyxoma (AAM). The patient was free of recurrence after 1 year of follow up.
AAM is a More >

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RESIDENT’S CORNER

Lee A. Richter^1,2, Michael Isaacson^1,2, Mohan Verghese², Jayashree Krishnan³
Canadian Journal of Urology, Vol.18, No.5, pp. 5911-5913, 2011
Abstract Malakoplakia involving the genitourinary tract is a rare infl ammatory disorder that presents a diagnostic challenge. Renal parenchymal involvement is particularly uncommon. We report a case of bilateral renal malakoplakia that presented with acute renal failure and simulated xanthogranulomatous pyelonephritis (XGP). The etiology, clinical course, and management of malakoplakia are reviewed, emphasizing the distinct characteristics of the disease that lead to its accurate diagnosis. More >

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RESIDENT’S CORNER

Benjamin T. Ristau, Jeffrey J. Tomaszewski, Anil V. Parwani, Michael C. Ost
Canadian Journal of Urology, Vol.18, No.5, pp. 5914-5915, 2011
Abstract We present the case of a 69-year-old male with incidentally discovered capillary hemangiomas at radical prostatectomy. Hemangiomas of genitourinary origin are extremely rare, typically benign vascular tumors. This finding represents the first reported hemangioma within a radical prostatectomy specimen. More >

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RESIDENT’S CORNER

Michael Mastromichalis, Daniel Sackman, James F. Tycast, Micheal J. Chehval
Canadian Journal of Urology, Vol.18, No.5, pp. 5916-5917, 2011
Abstract Not uncommonly, hostile prison environments can lead desperate prisoners to place foreign materials into natural orifi ces in an effort to gain transfer to an outside healthcare facility. In this article, we present a case series of urethral foreign body insertion of varying burdens and durations requiring transfer to our facility for surgical management. Endoscopic retrieval was the initial management in each case; one case required conversion to open cystotomy for complete removal due the orientation, amount of inserted foreign body, and erosion into the proximal urethral and bladder urothelium. More >

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HOW I DO IT

Kevin C. Zorn, Daniel Liberman
Canadian Journal of Urology, Vol.18, No.5, pp. 5918-5926, 2011
Abstract Transurethral resection of the prostate (TURP) is the most common surgical intervention for benign prostatic hyperplasia (BPH), largely due to lower urinary tract symptoms refractory to medical therapy. TURP remains the gold standard for men with prostates sized 30g-80g, while open prostatectomy has been the preferred option for men with glands larger than 80g-100 g and those with other lower urinary tract anomalies such as large bladder stones or bladder diverticula. Unfortunately, these procedures have complications including bleeding (often requiring transfusion in 7%-13% of cases), electrolyte abnormalities (2% TURP syndrome), erectile dysfunction (6%-10%), and retrograde… More >

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CLINICAL TRIALS

George Rodrigues, Eric Winquist
Canadian Journal of Urology, Vol.18, No.5, pp. 5927-5932, 2011
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LETTER

Leonard G. Gomella¹, Timothy B. Hopkins², Harry P. Koo³
Canadian Journal of Urology, Vol.18, No.5, pp. 5933-5933, 2011
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SUPPLYMENTS

Canadian Journal of Urology, Vol.18, No.5, pp. 5934-5950, 2011
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ABSTRACT

Canadian Journal of Urology, Vol.18, No.5, pp. 5952-5986, 2011
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