Predicting lymph node invasion in patients treated with robot-assisted radical prostatectomy
Firas Abdollah1, Dane E. Klett1, Jesse D. Sammon1,
Deepansh Dalela1, Akshay Sood1, Linda Hsu1,
Mireya Diaz1, Nilesh Gupta2, James O. Peabody1,
Quoc-Dien Trinh3, Mani Menon1
Canadian Journal of Urology, Vol.23, No.1, pp. 8141-8150, 2016
Abstract Introduction: To develop a nomogram to predict lymph
node invasion (LNI) in the contemporary North American
patient treated with robot-assisted radical prostatectomy
(RARP).
Materials and methods: We included 2,007 patients
treated with RARP and pelvic lymph node dissection
(PLND) at a single institution between 2008 and 2012.
D’Amico low risk patients underwent an obturator and
hypogastric PLND, while extended PLND was reserved
for intermediate/high risk patients. Logistic regression
analysis tested the relationship between LNI and all
available predictors. Independent predictors of LNI were
used to develop a novel nomogram. Discrimination,
calibration and decision-curve analysis were used to… More >