Open Access

EDITORIAL

Laurence H. Klotz
Canadian Journal of Urology, Vol.11, No.4, pp. 2312-2313, 2004
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LETTER

Kamran Darabi, Adam M. Segal, Gilberto Torres
Canadian Journal of Urology, Vol.11, No.4, pp. 2314-2314, 2004
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ARTICLE

S. Tyldesley¹, A. Coldman², T. Pickles¹
Canadian Journal of Urology, Vol.11, No.4, pp. 2316-2321, 2004
Abstract Objective: To determine whether men who relapse after neoadjuvant androgen ablation (NAA) and high-dose radiation therapy (RT) have faster PSA doubling times (PSAdt) than those who are treated with RT alone.
Materials and methods: From a prospective database of 1880 patients treated with RT for localized prostate cancer, patients were selected for further study if they had a rising PSA profile >1 ng/ml, and were treated with either no NAA, or prolonged NAA (defined as 3-12 months NAA) with a minimum 5 years follow-up. The PSAdt was calculated from the exponential line of best fit from the… More >

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ARTICLE

R. Asplund
Canadian Journal of Urology, Vol.11, No.4, pp. 2322-2326, 2004
Abstract Objective: To assess the relationship between nocturia, thirst and the perception of dryness in the eyes and mouth in a group of elderly men and women.
Materials and methods: The study comprised 6103 elderly men and women recruited by a questionnaire from a group of pensioners (n=10216; response rate 61.3%). The age of the men and the women was 73.0 (6.0) and 72.6 (6.7) years, respectively. The questionnaire included questions on their health, diseases and symptoms, drugs, sleep habits and the number of nocturnal voiding episodes.
Results: Dryness of the eyes increased from 6.5% in men without nocturnal… More >

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ARTICLE

Heather McDonald¹, Margaret Hux¹, Marc Brisson², Lisa Bernard¹, J. Curtis Nickel³
Canadian Journal of Urology, Vol.11, No.4, pp. 2327-2340, 2004
Abstract Objective: The Proscar Long-Term Efficacy and Safety Study (PLESS) and the Medical Therapy of Prostatic Symptoms (MTOPS) study provide new evidence regarding the benefits of finasteride in the treatment of benign prostatic hyperplasia (BPH). The objective of this study was to utilize data from the PLESS and MTOPS studies to assess the cost-utility of finasteride and finasteride in combination with doxazosin, compared to doxazosin alone in men with moderate to severe BPH symptoms.
Methods: A semi-Markov decision analytic model was constructed to estimate the clinical consequences, costs and cost-utility of doxazosin, finasteride, and combination therapy. Analyses were… More >

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CASE REPORT

Robert Adam¹, Sydney Katz², Ken Lee³, Michael Jewett⁴, Ronald Kodama⁵
Canadian Journal of Urology, Vol.11, No.4, pp. 2341-2343, 2004
Abstract A 24 year old uncircumcised man presented with a 1 month history of a painful, fungating lesion on his glans penis. Following biopsy, and further clinical developments, a diagnosis of Wegener’s Granulomatosis (WG) was made. The penile lesion was treated with surgical debridement, and a penile stump was salvageable. This is only the fourth case of WG initially presenting with a penile lesion to be reported in the literature. More >

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RESIDENT’S CORNER

Danny M. Rabah¹, Louis R. Bégin², Abdelrahman Zahran¹, Jacques Corcos¹
Canadian Journal of Urology, Vol.11, No.4, pp. 2344-2349, 2004
Abstract Objective: To evaluate and compare histological tissue reactions of the urinary bladder to human cadaveric fascia lata (CFX) slings and synthetic mesh.
Methods: Thirty rabbits were randomized to three groups: group A (multifilament - Surgipro Mesh®) 12 animals, group B (CFX) 12 animals, and group C (surgical controls) 6 animals. A piece of Mesh or CFX was fixed in direct contact with the anterior bladder neck wall. The control group simply underwent sham bladder manipulation. The animals were sacrificed at 6- and 12-week intervals, and their bladders were collected for histological analysis.
Results: Group A showed fibrosis within… More >

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RESIDENT’S CORNER

Jean-Baptiste Lattouf, Michael Mc Cormack, Louise Yelle, Rachid Hadjeres, Fred Saad
Canadian Journal of Urology, Vol.11, No.4, pp. 2350-2351, 2004
Abstract We present a case of a pathologic stage 1, right sided, non-seminomatous germ cell tumor recurrence in the left seminal vesicle, 20 years after initial diagnosis and treatment. The patient was treated with three salvage cycles of bleomycin, etoposide, and cisplatinum. At 24 months of follow-up after completion of chemotherapy, digital rectal and TRUS examinations revealed complete resolution of the lesion. We believe that this tumor is a late metastasis to the contralateral seminal vesicle. More >

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RESIDENT’S CORNER

Saleh Binsaleh¹, Mana Al-Assiri¹, Samuel Aronson², Andrew Steinberg¹
Canadian Journal of Urology, Vol.11, No.4, pp. 2352-2353, 2004
Abstract We report a case of septic shock complicating transrectal ultrasound guided prostate biopsy despite antibiotic prophylaxis with ciprofloxacin. Patient was recently treated with the same agent for other infectious illnesses. More >

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