Open Access

EDITORIAL

Leonard G. Gomella
Canadian Journal of Urology, Vol.30, No.4, pp. 11583-11583, 2023
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BOOK REVIEW

Selcuk Sarikaya
Canadian Journal of Urology, Vol.30, No.4, pp. 11584-11584, 2023
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LEGENDS IN UROLOGY

Don Lamm
Canadian Journal of Urology, Vol.30, No.4, pp. 11585-11587, 2023
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REVIEW

Mohamed Javid¹, Madhu Reddiboina², Mahendra Bhandari³
Canadian Journal of Urology, Vol.30, No.4, pp. 11588-11598, 2023
Abstract Introduction: Artificial generative intelligence (AGI) and large language models (LLMs) have gained significant attention in healthcare and hold enormous promise for transforming every aspect of our life and urology is no exception.
Materials and methods: We conducted a comprehensive literature search of electronic databases and included articles discussing AGI and LLMs in healthcare. Additionally, we have incorporated our experiences interacting with the ChatGPT and GPT-4 in different situations with real case reports and case constructs.
Results: Our review highlights the potential applications and likely impact of these technologies in urology, for differential diagnosis, prioritizing treatment options, and facilitating… More >

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ARTICLE

Maxwell Sandberg¹, Wyatt Whitman¹, Janmejay Hingu¹, Parth Thakker¹, Anita Rong², Caleb Bercu², Jacob Greenberg³, Ronald Davis III¹, Ashok Hemal¹, Matvey Tsivian¹
Canadian Journal of Urology, Vol.30, No.4, pp. 11599-11604, 2023
Abstract Introduction: There is an ongoing debate as to the appropriate regimen of antibiotic prophylaxis with transperineal (TP) biopsy. The objective of this study was to report the rate of infection following TP biopsy at a high-volume institution and assess the impact of single dose antibiotics at the time of biopsy versus outpatient antibiotics in preventing postprocedural infections.
Materials and methods: Records of men undergoing TP prostate biopsy from 2012 to 2022 were reviewed. Patients were divided into two groups, those who received single dose intravenous (IV) antibiotics at the time of biopsy (n = 440) and those… More >

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COMMENTARY

Roderick Clark, Jay D. Raman
Canadian Journal of Urology, Vol.30, No.4, pp. 11605-11606, 2023
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ARTICLE

Codrut Radoiu¹, Julian Jeberaeel¹, Raghav Madan¹, Nitin Vaishampayan^1,2, Steve Lucas^1,3, Alaa Hamada³, Nivedita Dhar^3,4
Canadian Journal of Urology, Vol.30, No.4, pp. 11607-11612, 2023
Abstract Introduction: Chronic radiation cystitis (CRC) can develop between 6 months and 20 years after radiation therapy that presents with symptoms of urinary frequency, urgency, bladder pain, and nocturia. Amniotic membrane (AM) is known to contain pro-regenerative properties and could thereby be a potential therapeutic modality for radiation-induced tissue injury of the bladder.
Materials and methods: CRC patients recalcitrant to previous treatments received amniotic bladder therapy (ABT) comprised of intra-detrusor injections of 100 mg micronized AM (Clarix Flo) diluted in 10 mL 0.9% preservative-free sodium chloride. Clinical evaluation and questionnaires (Interstitial Cystitis Symptom Index (ICSI), Interstitial Cystitis Problem… More >

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ARTICLE

Dylan Buller¹, Brooke Harnisch¹, Vikram Lyall², Michael Goltzman¹, Evelyn Neuber³, Alison Bartolucci³, Stanton Honig^1,4
Canadian Journal of Urology, Vol.30, No.4, pp. 11613-11618, 2023
Abstract Introduction: To evaluate patient preference for sperm disposition in case of death based on demographic factors and infertility etiology.
Materials and methods: This retrospective cohort study was performed at a university hospital-affiliated fertility center. Charts of 550 men undergoing cryopreservation for assisted reproductive technologies (ART) between 2016-2019 were reviewed to create a descriptive dataset. Patients previously signed consent forms stating their preference for sperm transfer to their partner or disposal in the event of their subsequent death. Patients undergoing sperm cryopreservation for the purpose of ART were analyzed to assess associations between demographic characteristics and etiology of… More >

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ARTICLE

Sagar R. Patel, Katherine A. Lowrey, Angeline Johny, Christopher P. Smith
Canadian Journal of Urology, Vol.30, No.4, pp. 11619-11623, 2023
Abstract Introduction: Prostatic urethral lifts (PUL) provide improvement in urinary symptoms for men with benign prostatic hyperplasia (BPH). The aim of this study is to determine operative factors associated with improvement in urinary symptoms after PUL in men with bothersome BPH.
Materials and methods: Men with BPH undergoing PUL at a single, tertiary center were identified from 2019 to 2022. Inclusion criteria included documented prostate volume as well as preoperative and postoperative cystoscopic images of the prostatic urethra. Multivariate regression modeling was performed to determine the predictive factors—including prostate volume, number of implants, and degree of unobstructed prostatic… More >

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ARTICLE

Jordan Sarver, Remington Farley, Shane Daugherty, Jordan Bilbrew, Joshua Palka
Canadian Journal of Urology, Vol.30, No.4, pp. 11624-11628, 2023
Abstract Introduction: Difficult and traumatic urethral catheterization is a common reason for urologic consult. Catheter insertion and management is common for patients who are managed in the hospital setting.
Materials and methods: A four-question survey was distributed across three hospitals at a single-institution.
Results: A total of 41 nursing staff responses were recorded. Forty-four percent of the nursing staff reported prior participation in a traumatic catheter insertion. Ninety percent of total responders reported a prior involvement with a difficulty catheter.
Conclusion: Patient morbidity and healthcare costs regarding traumatic and difficult catheterization is significant. Utility of protocols and education could potentially More >

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RESIDENT’S CORNER

Joaquin Fernandez-Alberti¹, Ramon Coronil², Alejandro Iotti³, Alejandro Nolazco¹, Marcelo Featherston¹
Canadian Journal of Urology, Vol.30, No.4, pp. 11629-11632, 2023
Abstract Calyceal diverticulum (CD) is a rare anatomic anomaly with an incidence of 0.2% to 0.6% in the patients undergoing renal imaging. They are considered benign lesions and malignancy is exceedingly rare. For diagnosis it is suggested to perform a multiphasic contrast-enhanced computed tomography (CT) evidencing a diverticulum of the pelvicalyceal system with thin-walled cavities communicating with the central collecting system. However, they can be usually mistaken as kidney cancers leading to unjustified nephrectomy. Here, we present a case of a 34-year-old patient who underwent surgery in 2022 due to suspected kidney cancer and histopathological analysis More >

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HOW I DO IT

Aly-Khan A. Lalani
Canadian Journal of Urology, Vol.30, No.4, pp. 11633-11638, 2023
Abstract For more than four decades, platinum-based chemotherapy regimens have served as the established standard-of-care for advanced urothelial carcinoma (aUC). However, advancements in our understanding of cancer biology and tumor microenvironment have reshaped the therapeutic landscape and prognosis of this incurable disease. Immune checkpoint inhibitors (ICIs) that target programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are firmly established tools in aUC management, leading to enhanced life span and improved quality of life for patients.
In patients who achieved stable disease or better following platinum-based chemotherapy, maintenance therapy with the PD-L1 antibody… More >

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HOW I DO IT

Bertie Zhang¹, Arinze J. Ochuba², Gregory R. Mullen³, Arun Rai³, Tareq Aro³, David M. Hoenig³, Zeph Okeke³, Jared S. Winoker^1,3
Canadian Journal of Urology, Vol.30, No.4, pp. 11639-11643, 2023
Abstract Percutaneous nephrolithotomy (PCNL) is the gold-standard treatment for large and complex renal stones. Though associated with higher stone-free rates compared to other minimally invasive stone procedures, this comes at the expense of increased morbidity including postoperative pain and discomfort. We describe our enhanced recovery after surgery (ERAS) protocol for PCNL with emphasis on the use of erector spinae plane blocks to improve patient satisfaction and reduce postoperative opioid use and bother. More >

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