Open Access

RESIDENT’S CORNER

Chronic lymphocytic leukemia/small lymphocytic lymphoma presenting as acute renal failure

Zachary Snow¹, Lauren S. Jones², Javier Piraino¹, Matthew Sterling¹

1 Main Line Health, Bryn Mawr, Pennsylvania, USA
2 Philadelphia College of Osteopathic Medicine, Philadelphia, Pennsylvania, USA
Address correspondence to Dr. Zachary Snow, Bryn Mawr Hospital, Main Line Health, 130 S. Bryn Mawr Avenue, Office 452, Bryn Mawr, PA 19010 USA

Canadian Journal of Urology 2022, 29(1), 11036-11039.

Abstract

Lymphoma of the urinary bladder is quite rare, accounting for a small percentage of all bladder neoplasms. Here we discuss the case of a 68-year-old male patient who initially presented with acute renal failure and severe bilateral hydronephrosis on ultrasound. Cross-sectional imaging further revealed a diffusely thickened bladder wall with extensive retroperitoneal and mesenteric lymphadenopathy. Bladder biopsies ultimately led to a diagnosis of stage IV chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). This is a rare instance of upper tract dilatation being the first sign of a widely disseminated hematologic malignancy.

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