Open Access

RESIDENT’S CORNER

Large cell differentiation of metastatic prostate cancer after androgen deprivation therapy

Rutveej Patel¹, Izak Faiena¹, Jules Geltzeiler²

1 Division of Urology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
2 Division of Urology, Jersey Shore University Medical Center, Neptune, New Jersey, USA
Address correspondence to Dr. Rutveej Patel, 1 Robert Wood Johnson Place, MEB 584A, New Brunswick, NJ 08901 USA

Canadian Journal of Urology 2015, 22(2), 7752-7754.

Abstract

We present a case of a 75-year-old male with a history of high risk prostate cancer who underwent androgen deprivation therapy and palliative radiation treatments for his disease. Subsequently, he presented with gross hematuria and severe lower urinary tract symptoms. A palliative transurethral resection of the prostate (TURP) at that time, demonstrated large cell differentiated neuroendocrine carcinoma with metastasis to the lung. We review the limited literature on this rare form of disease and present current treatment strategies.

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