Special Issues
Table of Content

From Mechanisms to Models: Data-Driven Innovation in Urological Disease Research

Submission Deadline: 30 April 2026 (closed) View: 609 Submit to Special Issue

Guest Editor(s)

Prof. Dr. Qiang Wei

Email: weiqiang339@126.com

Affiliation: Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Homepage:

Research Interests: urologic diseases, multi-omics, artificial intelligence, precision medicine

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Prof. Dehong Cao

Email: caodehong@scu.edu.cn

Affiliation: Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Homepage:

Research Interests: prostatic disorders, disease diagnosis, prediction model, machine learning, artificial intelligence

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Summary

Big data analytics is reshaping clinical urology, offering transformative tools to improve diagnostic accuracy, guide therapeutic decisions, and optimize patient outcomes. The integration of diverse, large-scale datasets—including genomics, medical imaging, electronic health records, and real-world clinical data—is unlocking new avenues for precision diagnosis, risk stratification, and individualized treatment in both benign and malignant urological diseases.


This Special Issue aims to highlight clinically oriented research that bridges advanced data science approaches with tangible applications in urological practice. We particularly welcome studies that incorporate artificial intelligence, machine learning, or predictive modeling with strong clinical validation—such as integration with surgical outcomes, pathology results, or treatment response data. Emphasis will be placed on work that demonstrates clear translational relevance and supports evidence-based decision-making in urology.


Topics of interest include, but are not limited to:
- Real-world data analysis to improve diagnostic or treatment outcomes in urology
- Multi-omics integration in prostate, bladder, kidney, or benign urological conditions
- Predictive modeling of treatment response or postoperative complications
- Precision medicine and individualized therapy supported by clinical datasets
- AI-assisted clinical decision-making in surgical and medical urology
- Biomarker discovery supported by large-scale data and clinical validation
- Outcome-based research using large-scale registries or hospital databases
- Risk stratification tools for urologic cancers and BPH in routine practice


By promoting research that translates data-driven insights into clinical utility, this Special Issue seeks to support innovations that are not only scientifically sound but also immediately relevant to patient care in urology.


Keywords

big data analytics, urological diseases, precision medicine, multi-omics integration, machine learning, personalized treatment, biomarker discovery

Published Papers


  • Open Access

    ARTICLE

    Unraveling the bidirectional association between mental disorders and prostatitis: insights from a genetic perspective

    Guancan Liang, Jian Pan, Ruixiang Dai, Ziyi Lin, Xunbao Wang, Teng Hou, Zhicheng Luo, Xiaoming Wang
    Canadian Journal of Urology, Vol.33, No.3, pp. 563-571, 2026, DOI:10.32604/cju.2026.074252
    (This article belongs to the Special Issue: From Mechanisms to Models: Data-Driven Innovation in Urological Disease Research)
    Abstract Background: The causal link between mental illness and prostatitis remains inconclusive, largely due to heterogeneity and potential confounders. This study explored the causal link between mental illness and prostatitis in men using Mendelian randomization (MR), and offered recommendations for enhancing future research. Methods: Publicly accessible genome-wide association study (GWAS) data were accessed via the IEU OpenGWAS platform and FinnGen database for this research. The inverse variance weighted (IVW) approach served as the primary Mendelian randomization analysis, while MR-Egger, weighted median, weighted mode, and simple mode methods were additionally applied to evaluate potential relationships between prostatitis… More >

  • Open Access

    REVIEW

    Modified versus traditional Devine procedure for pediatric concealed penis: a systematic review and meta-analysis#

    Jinwei Mao, Jie Deng, Xiqi Peng, Xunbao Wang, Song Wu
    Canadian Journal of Urology, Vol.33, No.3, pp. 657-673, 2026, DOI:10.32604/cju.2025.072113
    (This article belongs to the Special Issue: From Mechanisms to Models: Data-Driven Innovation in Urological Disease Research)
    Abstract Background: Concealed penis (CP) is a common congenital condition in pediatric urology, and surgical correction remains the mainstay of treatment. The modified Devine procedure (MDP) has been increasingly used, but its comparative safety and effectiveness relative to the traditional Devine procedure (TDP) remain unclear. This study aimed to compare the safety and effectiveness of the MDP with the TDP for the treatment of pediatric CP. Methods: This systematic review and meta-analysis was conducted in accordance with the PRISMA 2020 and AMSTAR guidelines. Prospective, retrospective, and randomized controlled studies comparing MDP and TDP for pediatric CP… More >

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