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RESIDENT’S CORNER

Synchronous transitional cell carcinoma and metastatic hepatocellular carcinoma in the urinary bladder: a case report

Nabeel Al-Brahim¹, Salem Alowami¹, Ian Davis², Dean Daya¹

1 Departments of Pathology and Molecular Medicine, McMaster University, Henderson General Hospital, Hamilton, Ontario, Canada
2 Department of Urology, McMaster University, Henderson General Hospital, Hamilton, Ontario, Canada
Address correspondence to Dr. D. Daya, Department of Anatomical Pathology, Henderson General Hospital, 711 Concession St, Hamilton, Ontario L8V 1C3 Canada

Canadian Journal of Urology 2004, 11(6), 2463-2466.

Abstract

An 83- year-old male presented with intermittent hematuria and obstructive symptoms. A CT scan of the abdomen and pelvis showed diffuse thickening of the urinary bladder and a large 10 cm liver mass. Histopathological examination of bladder biopsy demonstrated two distinct lesions. The surface showed non-invasive urothelial carcinoma and the submucosa demonstrated metastatic hepatocellular carcinoma showing bile pigment and expressed Hep Par 1 and CD10. To the best of our knowledge, this is the first case report of synchronous transitional cell carcinoma and metastatic hepatocellular carcinoma of the urinary bladder.

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