Open Access

ARTICLE

Perioperative stroke and myocardial infarction in urologic surgery

Da David Jiang^1,2, Kyle A. Gillis^1,2, Yiyi Chen³, Jason C. Hedges¹, Nicholas H. Chakiryan^1,2

1 Department of Urology, Oregon Health and Science University, Portland, Oregon, USA
2 O’Brien Research Group, Portland, Oregon, USA
3 Oregon Health and Science University, Knight Cancer Institute, Biostatistics Shared Resource, Portland, Oregon, USA
Address correspondence to Dr. Nicholas H Chakiryan, Department of Urology, Oregon Health & Science University, 3303 SW Bond Avenue, CH10U, Portland, Oregon 97239 USA

Canadian Journal of Urology 2021, 28(3), 10678-10684.

Abstract

Introduction: Perioperative stroke and myocardial infarction are uncommon but devastating thromboembolic complications. There is no comprehensive study detailing these complications for urologic procedures. The primary aim of this study is to determine which urologic procedures and patients carry the highest risk of perioperative stroke and myocardial infarction.
Materials and methods: The National Surgical Quality Improvement Program data set was reviewed from 2008-2017. Procedures coded under the urology specialty were included, and patients who had a perioperative stroke or myocardial infarction were identified. CPTs were stratified into clinically relevant procedure groups. Two multivariable logistic regression analyses were performed to determine preoperative and procedural risk factors for developing perioperative stroke or myocardial infarction. A multivariable logistic regression analysis was performed to determine the association between these complications and 30-day mortality.
Results: A total of 281,744 cases were included, identifying 392 strokes (0.14%) and 1,016 myocardial infarctions (0.36%). Age ≥ 70, hypertension, and disseminated cancer were the strongest preoperative risk factors for perioperative stroke or myocardial infarction. Cystectomy was the highest risk urologic procedure (stroke: OR 3.3, 95%CI 2.3-4.8; MI: OR 7.2, 95%CI 5.6-9.1). Thirty-day mortality was dramatically worse for patients who had a perioperative stroke or myocardial infarction.
Conclusions: Perioperative stroke and myocardial infarction were confirmed to be uncommon but devastating complications of urologic surgery, with incidence rates of 0.14% and 0.36%, respectively. Cystectomy was the highest-risk urologic procedure. Perioperative stroke and myocardial infarction were strongly associated with age ≥ 70, hypertension, and disseminated cancer.

---

Keywords

---