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Effectiveness of manual detorsion in the treatment of testicular torsion: systematic review and meta-analysis

Sinan Kılıç*

Department of Pediatric Surgery, Faculty of Medicine, Okan University, Istanbul, 34959, Turkiye

* Corresponding Authors: Sinan Kılıç. Email: email, email

Canadian Journal of Urology 2026, 33(3), 505-514. https://doi.org/10.32604/cju.2025.072049

Abstract

Objectives: Testicular torsion is the most common surgical cause of an acute scrotum. Manuel detorsion renewed attention as a practical initial treatment, particularly in the COVID-19 pandemic. This study aims to systematically review and meta-analyze the current literature to determine whether manual detorsion offers a viable alternative to immediate surgery in improving testicular salvage rates. Methods: A systematic review and meta-analysis were conducted in accordance with PRISMA guidelines and registered with PROSPERO (CRD420251039489). Studies including ≥30 male patients comparing manual detorsion and surgical exploration were included. Searches were performed in PubMed/MEDLINE, Scopus, TR Index, and Web of Science. Risk of bias was assessed using a predefined scoring system based on methodology, sample size, and follow-up objectivity. Data were synthesized using RevMan 5.4 to calculate pooled risk ratios. Results: Eight retrospective studies involving a total of 670 patients were included. Patients were divided into a manual detorsion group (G1, n = 394) and a surgical exploration group (G2, n = 316). Success rates of manual detorsion ranged from 15% to 76%, while orchiectomy rates were lower in G1 (0% to 10.3%) compared to G2 (0% to 43.8%). The pooled success rate of manual detorsion was 75.7%. Although orchiectomy rates appeared numerically lower in the manual detorsion group (3.8% vs. 29.2%), the pooled analysis did not demonstrate a statistically significant overall difference between the two groups (risk ratio [RR] = 1.23; 95% CI: 0.82–1.84; p = 0.31). Conclusion: Manual detorsion appears time-saving and effective maneuver. To our knowledge, this is the first meta-analysis focused exclusively on manual detorsion, and it supports its consideration as an initial management strategy in selected clinical scenarios.

Graphic Abstract

Effectiveness of manual detorsion in the treatment of testicular torsion: systematic review and meta-analysis

Keywords

testicular torsion; manual detorsion; orchiopexy; testicular atrophy

Supplementary Material

Supplementary Material File

Cite This Article

APA Style
Kılıç, S. (2026). Effectiveness of manual detorsion in the treatment of testicular torsion: systematic review and meta-analysis. Canadian Journal of Urology, 33(3), 505–514. https://doi.org/10.32604/cju.2025.072049
Vancouver Style
Kılıç S. Effectiveness of manual detorsion in the treatment of testicular torsion: systematic review and meta-analysis. Can J Urology. 2026;33(3):505–514. https://doi.org/10.32604/cju.2025.072049
IEEE Style
S. Kılıç, “Effectiveness of manual detorsion in the treatment of testicular torsion: systematic review and meta-analysis,” Can. J. Urology, vol. 33, no. 3, pp. 505–514, 2026. https://doi.org/10.32604/cju.2025.072049



cc Copyright © 2026 The Author(s). Published by Tech Science Press.
This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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