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Soluble intercellular adhesion molecule-1 (sICAM-1): an overview
1 Department of Food Commodities Science and Technology
2 Department of Bromatology, Medical Academy, Białystok, Poland
* Corresponding Author: Anna Witkowska
European Cytokine Network 2004, 15(2), 91-98.
Accepted 15 March 2004;
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Soluble intercellular adhesion molecule-1 (sICAM-1) represents a circulating form of ICAM-1 that is constitutively expressed or is inducible on the cell surface of different cell lines. It serves as a counter-receptor for the lymphocyte function-associated antigen (LFA-1). Interaction between ICAM-1, present on endothelial cells, and LFA-1 facilitates leukocyte adhesion and migration across the endothelium. ICAM-1 and its circulating form have been implicated in the development of any number of diseases.Keywords
sICAM-1; cancers; atherosclerosis; autoimmune diseases; nutrition
Cite This Article
APA Style
Witkowska, A.M., Borawska, M.H. (2004). Soluble intercellular adhesion molecule-1 (sICAM-1): an overview. European Cytokine Network, 15(2), 91–98.
Vancouver Style
Witkowska AM, Borawska MH. Soluble intercellular adhesion molecule-1 (sICAM-1): an overview. Eur Cytokine Network. 2004;15(2):91–98.
IEEE Style
A.M. Witkowska and M.H. Borawska, “Soluble intercellular adhesion molecule-1 (sICAM-1): an overview,” Eur. Cytokine Network, vol. 15, no. 2, pp. 91–98, 2004.
Copyright © 2004 The Author(s). Published by Tech Science Press.This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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