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The LIF cytokine: towards adulthood

Marina Trouillas, Claire Saucourt, Bertrand Guillotin, Xavier Gauthereau, Jean-Luc Taupin, Jean-François Moreau, Hélène Bœuf

Université de Bordeaux, CNRS-UMR-5164-CIRID, 33076 Bordeaux, France

* Corresponding Author: H. Bœuf, email

European Cytokine Network 2009, 20(2), 51-62. https://doi.org/10.1684/ecn.2009.0148

Abstract

The aim of this article is to recapitulate the key features of leukaemia inhibitory factor cytokine (LIF), to review its numerous physiological effects and to comment on the most recent data. We will also pres-ent results of transcriptome analyses, which have highlighted different categories of LIF targets, identified in murine embryonic stem (ES) cells and early derivatives. We hope to stimulate new research fields on this puz-zling cytokine, which, forty years after its discovery, has still not disclosed all its secrets.

Keywords

LIF, IL-6, ES cells, pleiotropy, chromatin, p531

Cite This Article

APA Style
Trouillas, M., Saucourt, C., Guillotin, B., Gauthereau, X., Taupin, J. et al. (2009). The LIF cytokine: towards adulthood. European Cytokine Network, 20(2), 51–62. https://doi.org/10.1684/ecn.2009.0148
Vancouver Style
Trouillas M, Saucourt C, Guillotin B, Gauthereau X, Taupin J, Moreau J, et al. The LIF cytokine: towards adulthood. Eur Cytokine Network. 2009;20(2):51–62. https://doi.org/10.1684/ecn.2009.0148
IEEE Style
M. Trouillas et al., “The LIF cytokine: towards adulthood,” Eur. Cytokine Network, vol. 20, no. 2, pp. 51–62, 2009. https://doi.org/10.1684/ecn.2009.0148



cc Copyright © 2009 The Author(s). Published by Tech Science Press.
This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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