Open Access
REVIEW
The LIF cytokine: towards adulthood
Université de Bordeaux, CNRS-UMR-5164-CIRID, 33076 Bordeaux, France
* Corresponding Author: H. Bœuf,
European Cytokine Network 2009, 20(2), 51-62. https://doi.org/10.1684/ecn.2009.0148
Accepted 20 March 2009;
Abstract
The aim of this article is to recapitulate the key features of leukaemia inhibitory factor cytokine (LIF), to review its numerous physiological effects and to comment on the most recent data. We will also pres-ent results of transcriptome analyses, which have highlighted different categories of LIF targets, identified in murine embryonic stem (ES) cells and early derivatives. We hope to stimulate new research fields on this puz-zling cytokine, which, forty years after its discovery, has still not disclosed all its secrets.Keywords
Cite This Article
Copyright © 2009 The Author(s). Published by Tech Science Press.This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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